This study presents the optimization and tuning of a simulation framework to improve its simulation accuracy while evaluating the energy utilization of electric buses under various mission scenarios. The simulation framework was developed using the l...
With the aim to improve technologies for EV or new energy industries and to create society with low environmental impact, Akita Prefecture has carried out the “EV Bus Technology Improvement Project”. The project developed an Akita-original electric b...
Real-time monitoring of lithium-ion capacitors (LICs) is crucial for ensuring reliability and predictive maintenance in dynamic applications such as electric transportation. However, traditional electrochemical impedance spectroscopy (EIS) techniques...
This paper investigates the design problem of an electric bus (E-bus) route with charging stations to smooth the operations between E-bus service and charging. The design variables include the locations of E-bus stops, number of charging piles at cha...
The greenhouse gases and air pollution generated by extensive energy use have exacerbated climate change. Electric-bus (e-bus) transportation systems help reduce pollution and carbon emissions. This study analyzed the minimization of construction cos...
The accelerating electrification of public transport systems has increased the need for objective and transparent decision-support tools in electric bus (e-bus) procurement. Although multi-criteria decision-making (MCDM) approaches are frequently emp...
When putting electric buses into practice in mass transit systems, the vehicle state management becomes a vital factor in the realization of a stable commercial operation. Aiming at achieving a sound bus operation, we installed a vehicle monitoring s...
This work presents a real-life demonstration of 23 heavy-duty (HD) public electric buses (e-buses) in Jaworzno, Poland, with three lengths: 8.9 m, 12 m, and 18 m. The e-bus demo is based on the development of baseline e-buses to optimize the operatio...
Green Houses Gas (GHG) emission reduction and fossil fuel economy are becoming important global issues. In Chinese cities, new commercial vehicles using diesel engines are not allow--new buses must be zero-emission electric vehicles (E-bus). A fully-...
Electric buses (E-buses) are gaining popularity in urban transportation due to their environmental benefits and operational efficiency. However, large-scale integration of E-buses and Vehicle-to-Grid (V2G) technology introduces scheduling complexitie...
The present paper proposes a new methodology to aid the electrification process of local public transport (LPT). In more detail, real drive cycles of traditional buses currently in use are evaluated together with other data to simulate the consumptio...
With the growing interest and popularity of electric vehicles (EVs), the electrification of buses has been progressing recently. To achieve the seamless operation of electric buses (e-Buses) for public transportation, some bus stations should play th...
To alleviate the problems of traffic congestion, excessive energy consumption, and the environmental pollution caused by private cars, it is essential to use public transportation (PT). However, passengers making multiple trips in a short time period...
Background/Objectives: Contrast-enhanced endobronchial ultrasound (CE-EBUS) is a minimally invasive technique that combines traditional endobronchial ultrasound (EBUS) with a contrast agent (sulfur hexafluoride), enhancing the visualization of blood...
Convex probe endobronchial ultrasound transbronchial needle aspirations (CP-EBUS-TBNAs) and radial probe endobronchial ultrasound transbronchial lung biopsies (RP-EBUS-TBLBs) can be performed under moderate sedation or general anesthesia. Moderate se...
Introduction: Large vessels are often encountered during endobronchial ultrasound (EBUS). Safety of traversing the vessels weighed against a more invasive procedure can be a dilemma. Material and methods: We describe a case series of 8 patients who...
Alzheimer’s disease (AD) is a neurodegenerative disease that affects the majority of people worldwide. To date, there is no cure for the disease, so new therapeutic targets need to be identified and studied. Acetylcholinesterase (AChE) and buty...
Alzheimer’s disease (AD) numbers among the most precipitative neurodegenerative disorders, constituting a constant subject of interest for medicinal chemistry researchers. The treatment of such disorders remains a challenge due to the complexit...
Introduction: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is the standard diagnostic method for sampling mediastinal and hilar lymph nodes. Non-diagnostic samples have led some pulmonologists to add a miniforceps biop...
Introduction: In recent years, there has been a growing development of molecularly targeted therapies for various types of solid tumors—in particular, in non-small-cell lung cancer (NSCLC). This has required the need for greater quantities of tissue...
A potential source of new inhibitors of cholinesterase enzymes are certain compounds of natural plant origin; therefore, in the study described herein we have determined the chemical composition and the acetylcholinesterase (AChE) and butyrylcholines...
Accurate localization of thoracic lymph nodes during endobronchial ultrasound (EBUS) is crucial for lung cancer staging, treatment planning, and prognostication. Artificial intelligence (AI) has the potential to support this process. Deep learning (D...
Background: Alzheimer’s disease is a serious and widespread neurodegenerative illness in the modern healthcare scenario. GSK-3β and BuChE are prominent enzymatic targets associated with Alzheimer’s disease. Co-targeting GSK3β an...
Artificial intelligence (AI) is increasingly investigated as a potential adjunct in the diagnosis and staging of lung cancer, particularly through integration with bronchoscopy and endobronchial ultrasound (EBUS). Deep learning models have been appli...
Background and Objectives: The application of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) has been markedly increased over the past decade. EBUS-TBNA is known to be a very safe and accurate procedure; however, the inc...
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a safe and accurate diagnostic procedure used for investigating mediastinal pathologies. It is usually performed using an oral approach. The nasal route has been proposed...
Mediastinal lymphadenopathy is a condition in which one or more mediastinal lymph nodes are enlarged for malignant or benign causes, generally more than 10 mm. For a long time, the only way to approach the mediastinum was surgery, while in last decad...
Introduction: The evidence for using vacuum suction during EBUS is sparse and the optimal suction pressure for obtaining adequate samples has not yet been determined. Our aim was to assess the influence of suction on the adequacy and diagnostic yield...
Clinical guidelines promote the identification of several targetable biomarkers to drive treatment decisions in advanced non-small cell lung cancer (NSCLC), but half of all patients do not have a viable biopsy. Specimens from endobronchial-ultrasound...
Background: Mediastinal staging plays a critical role in guiding treatment decisions for non-small cell lung cancer (NSCLC). While mediastinoscopy has been the gold standard for assessing mediastinal lymph node involvement, endobronchial ultrasound-g...
Background: The distinction between N2a and N2b in the lung cancer TNM 9th edition staging system has reduced the heterogeneity of prognosis using the previous staging system. Moreover, this distinction may enable new treatment approaches in non-smal...
EBUS-TBNA is the most common interventional pulmonology procedure performed globally and remains the cornerstone of the diagnosis and staging not only of lung cancer but also for other neoplastic, inflammatory, and infective pathologies of the medias...
Sarcoidosis is a multisystem granulomatous disease of unknown aetiology that frequently presents with mediastinal lymphadenopathy and often requires invasive diagnostic procedures. Endobronchial ultrasound-guided transbronchial needle aspiration (EBU...
Background: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is the standard minimally invasive technique for mediastinal lymph node sampling; however, its diagnostic performance is limited in diseases requiring preserved...
Sedation techniques in interventional flexible bronchoscopy and endobronchial ultrasound-guided transbronchial-needle aspiration (EBUS-TBNA) are inconsistent and the evidence for required general anesthesia under full anesthesiologic involvement is s...
Background: Ex vivo fluorescence laser scanning microscopes (FCMs) allow digital tissue imaging directly from fresh, unfixed specimens without the need for conventional histological slide preparation. To date, no data have been reported on the use of...
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a cornerstone in minimally invasive thoracic lymph node sampling. In lung cancer staging, precise assessment of lymph node position is crucial for clinical decision-makin...
Lung cancer is a deadly disease with a high mortality rate. Endobronchial ultrasonography (EBUS) is one of the methods for detecting pulmonary lesions. Computer-aided diagnosis of pulmonary lesions from images can help radiologists to classify lesion...
The essential oil (EO) of Salvia leucantha Cav. was isolated by steam distillation of the aerial parts collected in the South of Ecuador. Its physical properties were evaluated and the chemical composition of the oil was determined by GC-MS and GC-FI...
Since the discovery of EGFR mutations, treatment strategies have undergone major advances over the past two decades. Accordingly, molecular testing for oncogenic driver mutations is recommended at the time of diagnosis of advanced NSCLC. In addition,...
Background and Clinical Significance: Isolated mediastinal lymphadenopathy is an exceptionally rare and diagnostically challenging initial manifestation of microscopic polyangiitis (MPA), often mimicking malignancy or infection. This case highlights...
Background/Objectives: Lung cancer remains the leading cause of cancer-related mortality worldwide, with a high proportion of cases diagnosed at advanced stages. Accurate mediastinal staging is essential to guide optimal therapeutic decisions. This s...
Climate change, global warming, pollution, and energy crisis are the major growing concerns of this era, which have initiated the electrification of transport. The electrification of roadway transport has the potential to drastically reduce pollution...
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is often the only source of tumor tissue from patients with advanced, inoperable lung cancer. EBUS-TBNA aspirates are used for the diagnosis, staging, and genomic testing to...
Background/Objectives: EBUS-TBNA is a safe and minimally invasive procedure to evaluate hilar and mediastinal lymph nodes (LNs). The Franseen needle provides a transbronchial needle biopsy (TBNB). Various needle sizes are available. In the literature...
Background: The evolution of interventional pulmonology has necessitated the refinement of anesthetic techniques to ensure the safety and efficacy of procedures such as endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA), par...
Urban low-altitude bus operations require coordinated eVTOL route decisions under station time windows, dynamic passenger boarding and alighting, load-dependent energy consumption, opportunity charging, and battery safety requirements. We formulate a...
Sarcoidosis (SA) is a systemic granulomatous disorder of unknown etiology with lung and mediastinal lymph nodes (LNs) as the main location. T lymphocytes play important role in the formation of granulomas in SA, but still little is known about the ro...
This paper provides a comprehensive overview of the state-of-the-art related to the implementation of battery electric buses (BEBs) in cities. In recent years, bus operators have started focusing on the electrification of their fleet to reduce the ai...
A 54-year-old woman on dialysis due to chronic renal failure had a fever lasting 2 weeks and was referred to a hospital. Non-enhanced CT and blood tests showed no remarkable findings. She was hospitalized and received an antibacterial drug. Although...
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