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  • Review
  • Open Access
45 Citations
15,880 Views
18 Pages

Achilles Tendinopathy Pathogenesis and Management: A Narrative Review

  • Domiziano Tarantino,
  • Rosita Mottola,
  • Giuseppina Resta,
  • Rossana Gnasso,
  • Stefano Palermi,
  • Bruno Corrado,
  • Felice Sirico,
  • Carlo Ruosi and
  • Rocco Aicale

The Achilles tendon is the thickest and strongest tendon of the human body, and it is frequently injured during sports activity. The incidence of Achilles tendon pathologies has increased over recent decades, especially in the last few years, because...

(This article belongs to the Section Sport and Health)
  • Review
  • Open Access
15 Citations
10,893 Views
17 Pages

Application of Orthobiologics in Achilles Tendinopathy: A Review

  • Luciano C. Ramires,
  • Madhan Jeyaraman,
  • Sathish Muthu,
  • Navaladi Shankar A,
  • Gabriel Silva Santos,
  • Lucas Furtado da Fonseca,
  • José Fábio Lana,
  • Ramya Lakshmi Rajendran,
  • Prakash Gangadaran and
  • Alex Eickhoff
  • + 2 authors

9 March 2022

Orthobiologics are biological materials that are intended for the regeneration of bone, cartilage, and soft tissues. In this review, we discuss the application of orthobiologics in Achilles tendinopathy, more specifically. We explain the concepts and...

(This article belongs to the Section Cell Biology and Tissue Engineering)
  • Review
  • Open Access
29 Citations
16,246 Views
11 Pages

Conservative Treatment of Chronic Achilles Tendinopathy: A Systematic Review

  • Vito Pavone,
  • Andrea Vescio,
  • Giuseppe Mobilia,
  • Sara Dimartino,
  • Giovanni Di Stefano,
  • Annalisa Culmone and
  • Gianluca Testa

Achilles tendinopathy is a common musculoskeletal disorder. Athletes, runners and jumpers, and the sedentary are frequently affected. Numerous are the therapeutic choices to manage these kinds of disorders. The aim of this review is to analyze the av...

(This article belongs to the Section Functional Anatomy and Musculoskeletal System)
  • Article
  • Open Access
7 Citations
4,811 Views
10 Pages

17 May 2021

No consensus exists concerning the diagnostic role or cutoff value of the Achilles tendon thickness on ultrasonography (US) for the diagnosis of insertional Achilles tendinopathy. This study sought to assess the diagnostic utility of US measurement o...

(This article belongs to the Section Orthopedics)
  • Article
  • Open Access
6 Citations
6,772 Views
11 Pages

Effects of Achilles Tendon Moment Arm Length on Insertional Achilles Tendinopathy

  • Takuma Miyamoto,
  • Yasushi Shinohara,
  • Tomohiro Matsui,
  • Hiroaki Kurokawa,
  • Akira Taniguchi,
  • Tsukasa Kumai and
  • Yasuhito Tanaka

23 September 2020

Insertional Achilles tendinopathy (IAT) is caused by traction force of the tendon. The effectiveness of the suture bridge technique in correcting it is unknown. We examined the moment arm in patients with IAT before and after surgery using the suture...

(This article belongs to the Special Issue New Trends in Sport and Exercise Medicine)
  • Review
  • Open Access
7 Citations
17,992 Views
12 Pages

An Overview of Achilles Tendinopathy Management

  • Fabio Santacaterina,
  • Sandra Miccinilli,
  • Federica Bressi,
  • Silvia Sterzi and
  • Marco Bravi

29 September 2021

Background: Persistent tendon pain and swelling related to mechanical loading are the main signs of Achilles tendinopathy (AT). This condition is one of the most common tendinopathies of the lower limb affecting mainly athletes involved in running an...

(This article belongs to the Special Issue Feature Papers in Osteology)
  • Feature Paper
  • Review
  • Open Access
2 Citations
5,743 Views
19 Pages

27 November 2022

Achilles tendinopathy (AT) is the most common injury of the Achilles tendon and represents 55–65% of all Achilles tendon clinical diagnoses. AT is characterized by pain, swelling, and impaired performance. ATs can be divided into two types, acc...

  • Review
  • Open Access
2 Citations
2,487 Views
19 Pages

Does the Anatomical Type of the Plantaris Tendon Influence the Management of Midportion Achilles Tendinopathy?

  • Łukasz Olewnik,
  • Ingrid C. Landfald,
  • Bartosz Gonera,
  • Łukasz Gołek,
  • Aleksandra Szabert-Kajkowska,
  • Andrzej Borowski,
  • Marek Drobniewski,
  • Teresa Vázquez and
  • Kacper Ruzik

4 August 2025

Background: Midportion Achilles tendinopathy (Mid-AT) is a complex condition that may be exacerbated by anatomical variations of the plantaris tendon. Recent anatomical studies, particularly the classification proposed by Olewnik et al., have enhance...

(This article belongs to the Section Orthopedics)
  • Brief Report
  • Open Access
5 Citations
4,280 Views
7 Pages

Cadaveric and Ultrasound Validation of Percutaneous Electrolysis Approach at the Achilles Tendon as a Potential Treatment for Achilles Tendinopathy: A Pilot Study

  • Laura Calderón-Díez,
  • José Luis Sánchez-Sánchez,
  • Miguel Robles-García,
  • Pedro Belón-Pérez and
  • César Fernández-de-las-Peñas

Achilles tendon tendinopathy (AT) is a musculoskeletal condition characterized by pain in the Achilles tendon and impaired physical performance or sport activities. AT is difficult to treat, and the results are variable. Preliminary evidence suggests...

(This article belongs to the Special Issue Treatment of Foot and Ankle Injury and Public Health)
  • Review
  • Open Access
2 Citations
8,499 Views
21 Pages

Injectables in the Therapy of Mid-Portion Achilles Tendinopathy, a Descriptive Review

  • Daniela Poenaru,
  • Claudia Gabriela Potcovaru,
  • Miruna Ioana Sandulescu,
  • Mariana Constantinovici and
  • Delia Cinteza

21 May 2025

Achilles mid-portion tendinopathy is defined as a painful thickening of the tendon, identified also on different imagistic examinations, occurring in sport people as well in inactively middle-aged individuals. The chronic and/or relapsing evolution i...

(This article belongs to the Special Issue Orthopedic Disease Treatment and Management: Innovations, Challenges, and Future Directions)
  • Article
  • Open Access
9 Citations
5,377 Views
17 Pages

13 January 2025

Objectives: To determine if psychological factors, such as anxiety, depression, fear of movement and fear of rupture are associated with increased tendon-related disability, quantified by the Tendinopathy Severity Assessment-Achilles (TENDINS-A). Des...

(This article belongs to the Section Mental Health)
  • Review
  • Open Access
20 Citations
6,215 Views
16 Pages

Molecular and Structural Effects of Percutaneous Interventions in Chronic Achilles Tendinopathy

  • Christelle Darrieutort-Laffite,
  • Louis J. Soslowsky and
  • Benoit Le Goff

23 September 2020

Achilles tendinopathy (AT) is a common problem, especially in people of working age, as well as in the elderly. Although the pathogenesis of tendinopathy is better known, therapeutic management of AT remains challenging. Various percutaneous treatmen...

(This article belongs to the Special Issue Achilles Curse and Remedy: Tendon Diseases from Pathophysiology to Novel Therapeutic Approaches)
  • Article
  • Open Access
1 Citations
788 Views
13 Pages

10 February 2026

Background/Objective: Achilles tendinopathy (AT) is a disabling condition, and treatment options are limited in patients in whom corticosteroid injections are discouraged or contraindicated, including individuals with diabetes. Porcine collagen injec...

(This article belongs to the Special Issue Molecular Injection Therapy in Orthopedic and Musculoskeletal Disorders: Conservative Approaches and Innovative Treatments)
  • Article
  • Open Access
2 Citations
7,533 Views
8 Pages

Treatment of Calcific Insertional Achilles Tendinopathy: Knotless Internal Brace versus Knot-Tying Suture Bridge

  • Xiaodong Zhao,
  • Xiaolei Yang,
  • Yifan Hao,
  • Fujun Yang,
  • Zhenping Zhang,
  • Qirong Qian,
  • Peiliang Fu and
  • Qi Zhou

24 February 2023

Background: This study aimed to compare the knotless internal brace technique and the knot-tying suture bridge technique via the medial approach in the treatment of calcific Achilles tendinopathy. Methods: The clinical data of 25 cases of calcific Ac...

(This article belongs to the Special Issue Recent Advances in Orthopaedic Surgery and Pathogenesis)
  • Article
  • Open Access
16 Citations
4,439 Views
9 Pages

18 June 2021

Background: Studies have demonstrated that a sub-group of patients with medial Achilles pain exhibit Achilles tendinopathy with plantaris tendon involvement. This clinical condition is characterised by structural relationships and functional interfer...

(This article belongs to the Section Orthopedics)
  • Article
  • Open Access
3 Citations
3,333 Views
8 Pages

23 February 2023

Background and Objectives: Chronic painful midportion Achilles combined with plantaris tendinopathy can be a troublesome condition to treat. The objective was to prospectively follow patients subjected to ultrasound (US)- and color doppler (CD)-guide...

(This article belongs to the Special Issue Update on Orthopedic Surgeries of the Lower Extremity Diseases and Injuries)
  • Systematic Review
  • Open Access
35 Citations
14,031 Views
16 Pages

The Efficacy of Platelet-Rich Plasma Injection Therapy in the Treatment of Patients with Achilles Tendinopathy: A Systematic Review and Meta-Analysis

  • Djandan Tadum Arthur Vithran,
  • Wenqing Xie,
  • Michael Opoku,
  • Anko Elijah Essien,
  • Miao He and
  • Yusheng Li

28 January 2023

Background: Over the past few years, many studies have been conducted to evaluate the effectiveness of platelet-rich plasma (PRP) in treating musculoskeletal conditions. However, there is controversy about its benefits for patients with Achilles tend...

(This article belongs to the Section Orthopedics)
  • Article
  • Open Access
1,080 Views
15 Pages

10 May 2026

Background: The progression of orthopedic diseases such as rheumatism and tendinopathies can be affected by metabolic conditions. Recent research suggests that changes in nutrition may affect symptom severity and recovery in orthopedic diseases. This...

(This article belongs to the Special Issue The Role of Nutrition in Exercise and Sports—2nd Edition)
  • Systematic Review
  • Open Access
8 Citations
13,975 Views
14 Pages

Comparability of the Effectiveness of Different Types of Exercise in the Treatment of Achilles Tendinopathy: A Systematic Review

  • Aikaterini Pantelis Sivrika,
  • Eleni Papadamou,
  • George Kypraios,
  • Demetris Lamnisos,
  • George Georgoudis and
  • Dimitrios Stasinopoulos

11 August 2023

Achilles tendinopathy (AT) is a common condition both in athletes and the general population. The purpose of this study is to highlight the most effective form of exercise in managing pain-related symptoms and functional capacity as well as in a retu...

(This article belongs to the Special Issue New Advances in the Treatment of Chronic Musculoskeletal Pain)
  • Article
  • Open Access
14 Citations
10,562 Views
10 Pages

Ultrasound Imaging of the Abdominal Wall and Trunk Muscles in Patients with Achilles Tendinopathy versus Healthy Participants

  • Carlos Romero-Morales,
  • Pedro Martín-Llantino,
  • César Calvo-Lobo,
  • Marta San-Antolín,
  • Daniel López-López,
  • María Blanco-Morales and
  • David Rodríguez-Sanz

Purpose: To compare and quantify with ultrasound imaging (USI) the inter-recti distance (IRD), rectus abdominis (RA), external oblique (EO), internal oblique (IO), transversus abdominis (TrAb), and multifidus thickness and the RA and multifidus cross...

(This article belongs to the Special Issue Ultrasound Diagnosis and Guided Intervention of Musculoskeletal/Neuromuscular Pathology)
  • Article
  • Open Access
41 Citations
5,869 Views
18 Pages

Changes in Gene Expression Associated with Collagen Regeneration and Remodeling of Extracellular Matrix after Percutaneous Electrolysis on Collagenase-Induced Achilles Tendinopathy in an Experimental Animal Model: A Pilot Study

  • José Luis Sánchez-Sánchez,
  • Laura Calderón-Díez,
  • Javier Herrero-Turrión,
  • Roberto Méndez-Sánchez,
  • José L. Arias-Buría and
  • César Fernández-de-las-Peñas

15 October 2020

Percutaneous electrolysis is an emerging intervention proposed for the management of tendinopathies. Tendon pathology is characterized by a significant cell response to injury and gene expression. No study investigating changes in expression of those...

(This article belongs to the Special Issue Needling Interventions for the Management of Musculoskeletal Pain Syndromes)
  • Article
  • Open Access
23 Citations
12,067 Views
8 Pages

Ultrasonography Features of the Plantar Fascia Complex in Patients with Chronic Non-Insertional Achilles Tendinopathy: A Case-Control Study

  • Carlos Romero-Morales,
  • Pedro Javier Martín-Llantino,
  • César Calvo-Lobo,
  • Daniel López-López,
  • Rubén Sánchez-Gómez,
  • Blanca De-La-Cruz-Torres and
  • David Rodríguez-Sanz

2 May 2019

Purpose: The goal of the present study was to assess, by ultrasound imaging (USI), the thickness of the plantar fascia (PF) at the insertion of the calcaneus, mid and forefoot fascial locations, and the calcaneal fat pad (CFP) in patients with Achill...

(This article belongs to the Special Issue Sensors for Gait, Posture, and Health Monitoring)
  • Article
  • Open Access
1,806 Views
14 Pages

Background: Chronic insertional Achilles tendinopathy (CIAT) is a type of tendinopathy resistant to conventional conservative treatments. The efficacy of extracorporeal shock wave therapy (ESWT) remains controversial. This study aims to evaluate the...

  • Systematic Review
  • Open Access
1 Citations
3,378 Views
18 Pages

9 February 2026

Background: Anterior cruciate ligament (ACL) rupture, Achilles tendinopathy, and stress fracture are common sports injuries with significant long-term effects on performance and health. Despite similar exposure, injury susceptibility varies among ath...

(This article belongs to the Section Human Genomics and Genetic Diseases)
  • Case Report
  • Open Access
1 Citations
2,120 Views
17 Pages

Novel Sonoguided Digital Palpation and Hydrodissection for Sural Nerve Dysfunction Mimicking Achilles Tendinopathy in a Psoriasis Patient

  • Yonghyun Yoon,
  • King Hei Stanley Lam,
  • Howon Lee,
  • Chanwool Park,
  • Seungbeom Kim,
  • Minjae Lee,
  • Jaeyoung Lee,
  • Jihyo Hwang,
  • Hyemi Yu and
  • Kenneth Dean Reeves
  • + 4 authors

25 October 2025

Background and Clinical Significance: Psoriasis, a chronic immune-mediated inflammatory disease, can affect musculoskeletal structures, including the Achilles tendon. Achilles pain in psoriasis patients may arise from tendinitis or neuropathic pain d...

(This article belongs to the Special Issue Ultrasound Diagnosis and Guided Intervention of Musculoskeletal/Neuromuscular Pathology, Second Edition)
  • Article
  • Open Access
8 Citations
3,644 Views
13 Pages

Epigallocatechin-3-Gallate (EGCG)-Loaded Hyaluronic Acid Hydrogel Seems to Be Effective in a Rat Model of Collagenase-Induced Achilles Tendinopathy

  • Hwa Jun Kang,
  • Sivakumar Allur Subramanian,
  • Si Young Song,
  • Jihyun Hwang,
  • Collin Lee and
  • Sung Jae Kim

Tendon injuries account for 45% of musculoskeletal injuries. However, research on the occurrence and pathogenesis of tendinopathy is insufficient, and there is still much debate regarding treatment methods. It is important to understand the molecular...

(This article belongs to the Special Issue Novel Biomaterials for Tissue Engineering)
  • Article
  • Open Access
8 Citations
5,152 Views
15 Pages

31 January 2023

Background: As inter-limb asymmetries can be associated with higher injury risk, we aimed to investigate their role in Achilles tendinopathy patients. Methods: In Achilles tendinopathy patients (n = 41), we assessed inter-limb asymmetries of mechanic...

(This article belongs to the Section Sports Medicine)
  • Article
  • Open Access
2,040 Views
16 Pages

Histological Alterations and Interferon-Gamma and AKT-mTOR Expression in an Experimental Model of Achilles Tendinopathy—A Comparison of Stem Cell and Amniotic Membrane Treatment

  • Guilherme Vieira Cavalcante,
  • Rosangela Fedato,
  • Lucia de Noronha,
  • Seigo Nagashima,
  • Ana Paula Camargo Martins,
  • Márcia Olandoski,
  • Ricardo Pinho,
  • Aline Takejima,
  • Rossana Simeoni and
  • Luiz César Guarita-Souza
  • + 1 author

Achilles tendon injuries are extremely common and have a significant impact on the physical and mental health of individuals. Both conservative and surgical treatments have unsatisfactory results. The search for new therapeutic tools, using cell ther...

(This article belongs to the Section Cell Biology and Pathology)
  • Article
  • Open Access
23 Citations
5,646 Views
11 Pages

Treatment of Achilles Tendinopathy in Recreational Runners with Peritendinous Hyaluronic Acid Injections: A Viscoelastometric, Functional, and Biochemical Pilot Study

  • Marco Gervasi,
  • Elena Barbieri,
  • Italo Capparucci,
  • Giosuè Annibalini,
  • Davide Sisti,
  • Stefano Amatori,
  • Vittoria Carrabs,
  • Giacomo Valli,
  • Sabrina Donati Zeppa and
  • Piero Sestili
  • + 2 authors

31 March 2021

Background: Achilles tendinopathy (AT) affects ca. 10 million recreational runners in Europe; the practice of hyaluronic acid (HA) infiltration is being increasingly adopted. The aim of this pilot study was to monitor the effects of a three-local tim...

(This article belongs to the Special Issue Health, Quality of Life and Sport Rehabilitation)
  • Article
  • Open Access
1 Citations
733 Views

Prolotherapy for Achilles Tendinopathy

  • Hau Pham,
  • Wei Tseng,
  • Ewald R. Mendeszoon,
  • Amy Wong,
  • Rachel Hutchins,
  • Anish Amin and
  • Daniel B. Reubens

1 November 2025

Background: Prolotherapy (proliferative therapy) is a nonsurgical regenerative injection technique that introduces small amounts of hyperosmolar dextrose to the site of painful or degenerated tendons or their insertions. Under ultrasound guidance, a...

  • Article
  • Open Access
6 Citations
3,128 Views
15 Pages

Cellular and Structural Changes in Achilles and Patellar Tendinopathies: A Pilot In Vivo Study

  • Dimitrios Kouroupis,
  • Carlotta Perucca Orfei,
  • Diego Correa,
  • Giuseppe Talò,
  • Francesca Libonati,
  • Paola De Luca,
  • Vincenzo Raffo,
  • Thomas M. Best and
  • Laura de Girolamo

Tendinopathies continue to be a challenge for both patients and the medical teams providing care as no universal clinical practice guidelines have been established. In general, tendinopathies are typically characterized by prolonged, localized, activ...

(This article belongs to the Special Issue Recent Advances in Arthritis and Tendinopathy)
  • Article
  • Open Access
3 Citations
3,082 Views
10 Pages

6 April 2023

(1) Background: Achilles tendinopathy (AT) is characterized by load-induced tendon pain, stiffness, and functional impairment that may affect the tendon midportion or insertion. Platelet-rich fibrin matrix (PRFM) is a promising adjunctive therapy for...

(This article belongs to the Section Orthopedics)
  • Article
  • Open Access
29 Citations
231 Views

Surgery for Chronic Achilles Tendinopathy

  • Amol Saxena and
  • Steven Cheung

The authors reviewed 91 surgical procedures in 87 patients with chronic Achilles tendinopathy. There were 62 males and 25 females (mean age, 44.9 years). The average interval between surgery and review for the group was 4.2 years (range, 1 to 10 year...

  • Article
  • Open Access
4 Citations
647 Views

Surgical Treatment of Insertional Achilles Tendinopathy: A Systematic Review

  • Ruth Moen,
  • Jacob R. Hagenbucher and
  • Andrew B. Shinabarger

1 September 2020

Background: Insertional Achilles tendinopathy is a common complaint among patients. Oftentimes, conservative treatment is inadequate, and surgical treatment is required. However, there is no published consensus regarding surgical intervention in refe...

  • Article
  • Open Access
1 Citations
278 Views

Gouty Achilles Tendinopathy: A Case Report

  • Chandana Halaharvi,
  • Eric So,
  • Cherreen Tawancy,
  • Kurt A. Kibler and
  • Daniel Logan

Tendinopathy in the presence of gouty arthropathy is relatively common, yet the clinical suspicion for gout involvement in acute tendon pain remains low. A 49-year-old man presented with an acute, tender, erythematous mass to the right posterior heel...

  • Article
  • Open Access
1 Citations
887 Views
21 Pages

15 February 2026

Background/Objectives: Insertional Achilles tendinopathy (IAT) is frequently associated with posterior calcaneal spurs; however, the prognostic significance of spur morphology for patient-centered treatment outcomes remains unquantified. This study a...

(This article belongs to the Section Orthopedics)
  • Article
  • Open Access
17 Citations
6,656 Views
14 Pages

The Burden and Risk Factors of Patellar and Achilles Tendinopathy in Youth Basketball: A Cohort Study

  • Oluwatoyosi B. A. Owoeye,
  • Luz Palacios-Derflingher,
  • Kati Pasanen,
  • Tate HubkaRao,
  • Preston Wiley and
  • Carolyn A. Emery

This study aimed at evaluating the burden and risk factors of patellar and Achilles tendinopathy among youth basketball players. Patellar and Achilles tendinopathy were prospectively monitored in 515 eligible male and female youth basketball players...

(This article belongs to the Special Issue Injury Prevention in Sport)
  • Article
  • Open Access
3 Citations
3,094 Views
15 Pages

Sex Differences and Extracorporeal Shockwave Therapy Outcomes in Runners with Achilles or Hamstring Tendinopathy

  • Nicole B. Katz,
  • Sydney C. Karnovsky,
  • David M. Robinson,
  • Stephanie E. DeLuca,
  • Phillip H. Yun,
  • Ellen Casey,
  • Meagan M. Wasfy and
  • Adam S. Tenforde

3 December 2024

Background/Objectives: Achilles and hamstring tendinopathies are common injuries in runners, and extracorporeal shockwave therapy (ESWT) may be an effective treatment. Runners are at risk for lower extremity tendinopathies and the Male and Female Ath...

(This article belongs to the Section Clinical Rehabilitation)
  • Article
  • Open Access
1 Citations
149 Views

Tropical Achilles Tendinopathy: Sea Urchin Spine Injury

  • Roger A. Sanguino,
  • Jennifer Cheng and
  • James F. Wyss

Sea urchin spine injuries have been reported in the hand and foot, but there are no published cases in the Achilles tendon. We report an unusual case of Achilles tendinopathy secondary to sea urchin spine injury. The patient had Achilles tendon pain...

  • Feature Paper
  • Review
  • Open Access
3 Citations
12,967 Views
11 Pages

Effectiveness of Kinesiotherapy in the Treatment of Achilles Tendinopathy—A Narrative Review

  • Robert Trybulski,
  • Jarosław Muracki,
  • Mieszko Podleśny,
  • Andriy Vovkanych and
  • Adrian Kużdżał

25 July 2024

This narrative review of kinesiotherapy methods in the treatment of Achilles tendinopathy (AT) encompassed a diverse range of studies, including athletes and untrained people, healthy or injured, undergoing kinesiotherapy treatments. Most experimenta...

  • Review
  • Open Access
19 Citations
32,232 Views
14 Pages

Background: Achilles tendinopathy is a common health condition encountered in the orthopedic and sports medicine settings. Eccentric exercise is a common intervention in the management of pain and limited function for this patient population, althoug...

(This article belongs to the Special Issue Eccentric Exercise: Adaptations and Applications for Health and Performance)
  • Article
  • Open Access
2 Citations
5,135 Views
10 Pages

A New Test for Achilles Tendinopathy Based on Kager’s Fat Pad Clinical Assessment Predictive Values

  • David Rodríguez-Sanz,
  • Marta Elena Losa-Iglesias,
  • Ricardo Becerro de Bengoa-Vallejo,
  • Zacarías Sánchez-Milá,
  • Hend Adel Abdelhalim Dorgham,
  • Ahmed Ebrahim Elerian,
  • Tian Yu,
  • César Calvo-Lobo,
  • Jorge Velázquez-Saornil and
  • Eva María Martínez Jimene

9 August 2023

Background This study aimed to check the diagnostic accuracy of a new test to identify Achilles tendinopathy. Study Design: Observational study. Methods: Seventy patients recruited from a private medical centre met the diagnostic criteria for unilate...

(This article belongs to the Section Nuclear Medicine & Radiology)
  • Article
  • Open Access
4 Citations
161 Views

1 September 2018

Plantaris tendon disorders are a well-known source of midportion Achilles tendinopathy. Plantaris tendon thickening and fibrous tissue formation between the tendons are the histologic abnormalities that are typically observed. Surgical approaches (sc...

  • Article
  • Open Access
807 Views
9 Pages

Background: Treatment of chronic painful insertional Achilles tendinopathy is known to be challenging. If non-surgical treatment does not give sufficient relief of symptoms, surgery may be indicated. Treatment with ultrasound (US)- and colour Doppler...

(This article belongs to the Special Issue Innovative Therapies for Achilles Tendon Injuries)
  • Article
  • Open Access
67 Citations
60,758 Views
16 Pages

Oral Supplementation of Specific Collagen Peptides Combined with Calf-Strengthening Exercises Enhances Function and Reduces Pain in Achilles Tendinopathy Patients

  • Stephan F.E. Praet,
  • Craig R. Purdam,
  • Marijke Welvaert,
  • Nicole Vlahovich,
  • Gregg Lovell,
  • Louise M. Burke,
  • Jamie E. Gaida,
  • Silvia Manzanero,
  • David Hughes and
  • Gordon Waddington

2 January 2019

The current pilot study investigates whether oral supplementation of specific collagen peptides improves symptoms and tendon vascularisation in patients with chronic mid-portion Achilles tendinopathy in combination with structured exercise. Participa...

(This article belongs to the Special Issue Collagen and Human Health)
  • Article
  • Open Access
7 Citations
4,944 Views
10 Pages

Prevalence of Coexistent Plantaris Tendon Pathology in Patients with Mid-Portion Achilles Pathology: A Retrospective MRI Study

  • Sachin Khullar,
  • Prasanna Gamage,
  • Peter Malliaras,
  • Leesa Huguenin,
  • Ashutosh Prakash and
  • David Connell

22 May 2019

Co-existence of Plantaris tendinopathy (PT) in patients with mid-Achilles tendinopathy (Mid-AT) is of clinical significance. This study aims to describe the MRI-based pathological characteristics of co-existing PT and Mid-AT. One-hundred MRI studies...

  • Review
  • Open Access
14 Citations
8,095 Views
18 Pages

Extensive Ossification of the Achilles Tendon with and without Acute Fracture: A Scoping Review

  • Daniel Sullivan,
  • Allison Pabich,
  • Ryan Enslow,
  • Avery Roe,
  • Donald Borchert,
  • Keenan Barr,
  • Bailey Cook and
  • Amanda Brooks

6 August 2021

Extensive Ossification of the Achilles Tendon (EOAT) is an uncommon condition characterized by the presence of heterotopic ossification within the substance of the Achilles Tendon and is distinct from other tendinopathies associated with tendon miner...

(This article belongs to the Special Issue Achilles Tendon Ailments: From the Bedside to the Bench)
  • Review
  • Open Access
3 Citations
14,125 Views
15 Pages

15 October 2025

Fluoroquinolones, one of the most frequently used antibiotics, despite their wide spectrum of beneficial activity, are linked to serious adverse effects such as tendinopathies. Tendon injuries connected to the use of the group of drugs frequently aff...

(This article belongs to the Special Issue Redox Homeostasis and Oxidative Stress in Human Metabolism and Disease:2nd Edition)
  • Article
  • Open Access
5 Citations
5,325 Views
16 Pages

A Prospective Randomized Pilot Study on the Efficacy of a Dietary Supplementation Regimen of Vitamin E and Selenium for the Prevention of Fluoroquinolone-Induced Tendinopathy

  • Oana-Maria Mișcă,
  • Liviu-Coriolan Mișcă,
  • Bogdan Huzum,
  • Andreea-Adriana Neamţu,
  • Simona Cerbu,
  • Daniel-Raul Chioibaș,
  • Petrișor Zorin Crăiniceanu and
  • Andrei Gheorghe Marius Motoc

15 April 2025

Background: Fluoroquinolone-induced tendinopathy is a clinically significant adverse effect associated with this class of antibiotics, particularly affecting the Achilles tendon. Despite its growing recognition, the precise pathophysiological mechani...

(This article belongs to the Special Issue Fluoroquinolones)
  • Article
  • Open Access
30 Citations
5,128 Views
12 Pages

Treatment with Human Amniotic Suspension Allograft Improves Tendon Healing in a Rat Model of Collagenase-Induced Tendinopathy

  • Laura de Girolamo,
  • Luiz Felipe Morlin Ambra,
  • Carlotta Perucca Orfei,
  • John P. McQuilling,
  • Kelly A. Kimmerling,
  • Katie C. Mowry,
  • Kimberly A. Johnson,
  • Amy T. Phan,
  • Jessica L. Whited and
  • Andreas H. Gomoll

8 November 2019

Treatment of tendon injuries is challenging, with neither conservative nor surgical approaches providing full recovery. Placental-derived tissues represent a promising tool for the treatment of tendon injuries. In this study, human amniotic suspensio...

(This article belongs to the Special Issue Advances in Musculoskeletal Cell Therapy: Basic Science and Translational Approaches)

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