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Special Issue "Advances in Musculoskeletal Cell Therapy: Basic Science and Translational Approaches"
Deadline for manuscript submissions: 29 February 2020.
Interests: mesenchymal stem cells; cartilage; intervertebral disc; genes
Interests: mesenchymal stem cells; arthritis; exosomes; miRNA
The unstoppable progression of knowledge of the pathophysiological processes affecting bony, articular, and muscular structures allows for the continuous identification of new therapeutic targets and agents to be exploited in addressing the degenerative mechanisms affecting the musculoskeletal system.
The ultimate goal is to validate the results of in vitro studies in preclinical in vivo models, and subsequently translate the most promising therapies to clinical practice. The cutting-edge approaches are multiple, from the development of advanced in vitro models for the study of pathophysiological process to the implementation of cell-based therapies, including those that only involve cell paracrine activity or the combination of cells and scaffolds in tissue engineering approaches. In this context, progenitor cells, either stem or tissue specific, are fundamental as both actors and as in situ targets, due to their ability to promote a trophic and anti-inflammatory microenvironment.
The purpose of this Special Issue is to collect reports concerning advances in musculoskeletal cell therapy to drive researchers and clinicians towards innovative perspectives for the treatment of degenerative orthopaedic diseases.
Dr. Alessandra Colombini
Dr. Enrico Ragni
Dr. Silvia Lopa
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- stem cells
- regenerative medicine
- clinical translation
- in vitro models
- cell-free approaches