Molecular Injection Therapy in Orthopedic and Musculoskeletal Disorders: Conservative Approaches and Innovative Treatments
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Orthopedics".
Deadline for manuscript submissions: 31 January 2026 | Viewed by 1285
Special Issue Editors
Interests: molecular therapy; nucleic acids; tendinitis; statistics; analytical data management
Special Issues, Collections and Topics in MDPI journals
Interests: traumatology; articular disorders; tendinitis; rehabilitation; conservative treatment
Special Issues, Collections and Topics in MDPI journals
Interests: shoulder pathologies; injection therapy; rehabilitation; conservative approach
Special Issue Information
Dear Colleagues,
It is a great pleasure to present the following Special Issue in this journal: “Molecular Injection Therapy in Orthopedic and Musculoskeletal Disorders: Conservative Approaches and Innovative Treatments”, inside the orthopedic field. As we know, chronic pain and traumatic injuries in musculoskeletal disorders represent a significant and widespread health problem. These health difficulties affect people of all ages, negatively impacting the quality of life from a social, economic, and (not least) health point of view. In some cases, various surgical treatments are unavoidable and lead to various problems. When the clinical-surgical approach is deferrable towards physiotherapy, this has played a crucial role in improving the physio-psycho-social conditions of orthopedic patients. Nevertheless, therapies based on emerging minimally invasive approaches, including infiltrations of drugs, substances, or medical devices, are showing promising results in pain management, improving functionality, and accelerating recovery. Among these, hyaluronic acid, collagen, polynucleotides, platelet-rich plasma, and corticosteroids certainly stand out. These procedures can often be assisted by ultrasound imaging in order to increase the loco-regional positioning of the treatment. In the orthopedic field, there is already evidence that demonstrates the use of these combinations in conservative clinical decisions as a valid therapeutic alternative for musculoskeletal disorders.
This Special Issue aims to illustrate to the readers the updated evidence (also clinical experimental) and their consequent conservative clinical approach to the diagnosis and treatment of musculoskeletal disorders. This new evidence will be useful to raise awareness of the application of an appropriate conservative treatment. Original articles, systematic reviews, or meta-analyses are welcome.
We look forward to your contributions.
Dr. Niccola Funel
Prof. Dr. Paolo Domenico Parchi
Guest Editors
Dr. Andrea del Chiaro
Guest Editor Assistant
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Keywords
- injection therapy
- conservative approaches
- medical devices
- collagen
- polyribonucleotide
- plasma-rich platelets
- hyaluronic acids
- anti-inflammatory therapy
- tendinitis, osteoarthritis, musculoskeletal disorder, pain reduction
- regenerative medicine
- new clinical approaches
- physiotherapy
- comparative studies: surgery vs. conservative approaches
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