Molecular Injection Therapy in Orthopedic and Musculoskeletal Disorders: Conservative Approaches and Innovative Treatments

Dear Colleagues,

It is a great pleasure to present the following Special Issue in this journal: “Molecular Injection Therapy in Orthopedic and Musculoskeletal Disorders: Conservative Approaches and Innovative Treatments”, inside the orthopedic field. As we know, chronic pain and traumatic injuries in musculoskeletal disorders represent a significant and widespread health problem. These health difficulties affect people of all ages, negatively impacting the quality of life from a social, economic, and (not least) health point of view. In some cases, various surgical treatments are unavoidable and lead to various problems. When the clinical-surgical approach is deferrable towards physiotherapy, this has played a crucial role in improving the physio-psycho-social conditions of orthopedic patients. Nevertheless, therapies based on emerging minimally invasive approaches, including infiltrations of drugs, substances, or medical devices, are showing promising results in pain management, improving functionality, and accelerating recovery. Among these, hyaluronic acid, collagen, polynucleotides, platelet-rich plasma, and corticosteroids certainly stand out. These procedures can often be assisted by ultrasound imaging in order to increase the loco-regional positioning of the treatment. In the orthopedic field, there is already evidence that demonstrates the use of these combinations in conservative clinical decisions as a valid therapeutic alternative for musculoskeletal disorders.

This Special Issue aims to illustrate to the readers the updated evidence (also clinical experimental) and their consequent conservative clinical approach to the diagnosis and treatment of musculoskeletal disorders. This new evidence will be useful to raise awareness of the application of an appropriate conservative treatment. Original articles, systematic reviews, or meta-analyses are welcome.

We look forward to your contributions.

Dr. Niccola Funel
Prof. Dr. Paolo Domenico Parchi
Guest Editors

Dr. Andrea del Chiaro
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.