Redox Homeostasis and Oxidative Stress in Human Metabolism and Disease：2nd Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Endocrinology and Metabolism".
Deadline for manuscript submissions: 20 September 2025 | Viewed by 1198
Special Issue Editors
Interests: reactive oxygen species; oxidative stress; antioxidants; lipid peroxidation; exercise biochemistry; cryostimulation; parasitology
Special Issues, Collections and Topics in MDPI journals
Interests: reactive oxygen species; oxidative stress; antioxidants; oncology; metabolic diseases
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The finely tuned equilibrium of redox reactions forms the bedrock of many cellular functions underlying key metabolic processes and influencing the health of tissues and organs. This balance, critical for cell functionality, is frequently compromised in a myriad of diseases, including metabolic disorders, degenerative conditions and various other pathophysiological states. Perturbations in redox homeostasis often result from an imbalance between the production of reactive oxygen species (ROS) and antioxidant response mechanisms. At physiological levels, ROS serve as pivotal signaling molecules in a wide range of metabolic activities. However, excessive ROS accumulation can deleteriously perturb metabolic functions, instigating a diseased state and accelerating its progression. Furthermore, the intimate relationship between redox dynamics and human metabolism becomes even more complex when considering the influence of exogenous factors. These agents, in varied concentrations, can either maintain a redox equilibrium, thereby aiding metabolic function, or disrupt it, exacerbating oxidative stress. A deeper grasp of these multifaceted interactions is crucial not only for understanding disease etiology, but also devising innovative therapeutic interventions and preventive measures.
In this vein, this Special Issue invites submissions of original research articles that shed light on the intricate dance of redox signaling within metabolic contexts, both in health and disease. Articles highlighting the potential therapeutic strategies targeting redox imbalances in metabolic disorders are particularly encouraged. Additionally, comprehensive review articles that evaluate and dissect the current knowledge landscape pertaining to the theme are most welcome.
Prof. Dr. Alina Woźniak
Dr. Jaroslaw Nuszkiewicz
Guest Editors
Manuscript Submission Information
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Keywords
- antioxidants
- biomarkers
- cellular functions
- disease etiology
- disease progression
- metabolic disorders
- metabolic signaling
- oxidative stress
- pathophysiological states
- reactive oxygen species
- redox homeostasis
- redox signaling
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