It is widely recognized that macrophage cholesterol efflux mediated by the ATP-binding cassette transporter A1 (ABCA1) constitutes the initial and rate-limiting step of reverse cholesterol transport (RCT), displaying a negative correlation with the d...
MPEG-1 Layer 3 (MP3) is one of the most popular compression formats used for sound and especially for music. However, during the coding process, the MP3 algorithm negatively affects the spectral and dynamic characteristics of the audio file being com...
The protein kinase Mps1 (monopolar spindle 1) is an important regulator of the Spindle Assembly Checkpoint (SAC), the evolutionary conserved checkpoint system of higher organisms that monitors the proper bipolar attachment of all chromosomes to the m...
To improve motion accuracy through functional electrical stimulation (FES) of forearm muscles, feedback control laws are applied to the index finger’s metacarpophalangeal (MP) joint. This paper introduces a proxy-based super-twisting algorithm...
Background: To evaluate the clinical utility of an Artificial Intelligence (AI) radiology solution, Quantib Prostate, for prostate cancer (PCa) lesions detection on multiparametric Magnetic Resonance Images (mpMRI). Methods: Prostate mpMRI exams of 1...
Most of the ground in Japan is soft, leading to great damage in the event of liquefaction. Various ground-improvement measures are being taken to suppress such damage. However, it is difficult to carry out ground-improvement work while checking the i...
Mitogen-activated protein kinase (MAPK) signaling pathways are evolutionarily conserved in eukaryotes and modulate responses to both internal and external stimuli. Pmk1 and Mps MAPK pathways regulate stress tolerance, vegetative growth and cell wall...
This paper proposes an adaptive coordinated multi point (CoMP) scheme using pre-coding in order to improve the reliability of wireless communication systems based on orthogonal frequency division multiplexing (OFDM). In the conventional scheme, the r...
Cytoplasmic calcium ([Ca2+]cyt) is a well-characterized second messenger in eukaryotic cells. An elevation in [Ca2+]cyt levels is one of the earliest responses in plant cells after exposure to a range of environmental stimuli. Advances in understandi...
Magnaporthe oryzae (M. oryzae) is a phytopathogenic fungus that inflicts damage on vital crops, particularly rice. Its asexual reproduction leads to the generation of numerous conidia, which is a critical factor contributing to the prevalence of rice...
Diabetes mellitus (DM) is one of the major causes of death in the world. There are two types of DM—type 1 DM and type 2 DM. Type 1 DM can only be treated by insulin injection whereas type 2 DM is commonly treated using anti-hyperglycemic agents...
Increasingly sophisticated antivirus (AV) software and the growing amount and complexity of malware demand more processing power from personal computers, specifically from the central processor unit (CPU). This paper conducted performance tests with...
Photocatalysis can reduce CO2 to available energy by means of light energy, which is considered to be an effective solution to alleviate energy and environmental problems. In this paper, an MPS@Bi2WO6 composite photocatalyst was prepared by in situ h...
A novel analytical method for accurate determination of boron (B), phosphorous (P), and molybdenum (Mo) content in biosludge samples based on a relatively recent analytical technique, microwave plasma atomic emission spectrometry (MP-AES), is develop...
The first generation of near-infrared, genetically encoded calcium indicators (NIR-GECIs) was developed from bacterial phytochrome-based fluorescent proteins that utilize biliverdin (BV) as the chromophore moiety. However, NIR-GECIs have some main dr...
Alcohol-associated liver disease is a global health burden with high morbidity and mortality, and the fungal microbiome is important for its progression. In particular, Candida albicans and C. albicans-reactive T helper 17 (Th17) cells contribute to...
The subway alleviates the traffic pressure in the city but also brings the potential risk of land subsidence. The land subsidence caused by the subway is a global problem that seriously affects the safety of subway operations and surrounding building...
Inhibition of the protein kinase MPS1, a mitotic spindle-checkpoint regulator, reinforces the effects of multiple therapies against glioblastoma multiforme (GBM) in experimental settings. We analyzed MPS1 mRNA-expression in gliomas WHO grade II, III...
An evaluation was conducted of the colonization of Pseudomonas protegens MP12, a plant-growth promoting and antagonistic strain, inoculated in vine plants during a standard process of grapevine nursery propagation. Three in vivo inoculation protocols...
Osteoporosis and age-related bone loss increase bone fracture risk and impair bone healing. The need for identifying new factors to prevent or treat bone loss is critical. Previously, we reported that young MRL/MpJ mice have superior bone microarchit...
Antimitotic compounds, targeting key spindle assembly checkpoint (SAC) components (e.g., MPS1, Aurora kinase B, PLK1, KLP1, CENPE), are potential alternatives to microtubule-targeting antimitotic agents (e.g., paclitaxel) to circumvent resistance and...
Due to the limitations of satellite antenna technology, current operational microwave soil moisture (SM) data products are typically at tens of kilometers spatial resolutions. Many approaches have thus been proposed to generate finer resolution SM da...
This paper proposes an optimal strategy to parallelize the solution of large 3D magneto-quasi-static (MQS) problems, by combining the MPI and OpenMP approaches. The studied numerical problem comes from a weak-form integral formulation of a MQS proble...
Introduction: Hematopoietic stem cell transplantation (HSCT) comprises one of the two main treatment regimens for patients with mucopolysaccharidoses (MPS). There is a scarcity of literature concerning the process of growth in children with Mucopolys...
The matrix information geometric signal detection (MIGSD) method has achieved satisfactory performance in many contexts of signal processing. However, this method involves many matrix exponential, logarithmic, and inverse operations, which result in...
In the present study, an iron(II)-nanoscale organic complex (Fe-NO) was used as an enhancement factor by two different Rhodopseudomonas species of purple non-sulphur bacteria (PNSB) to produce hydrogen (H2). The Fe-NO complex was synthesised using Fe...
The paper investigates various implementations of a master–slave paradigm using the popular OpenMP API and relative performance of the former using modern multi-core workstation CPUs. It is assumed that a master partitions available input into a batc...
The aim of this review is to summarise recent scientific literature regarding the clinical use of DCE-MRI as a component of multiparametric resonance imaging of the prostate. This review presents the principles of DCE-MRI acquisition and analysis, th...
In skin lesions, the development of microbial infection affects the healing process, increasing morbidity and mortality rates in patients with severe burns, diabetic foot, and other types of skin injuries. Synoeca-MP is an antimicrobial peptide (AMP)...
Land surface models (LSMs) play a crucial role in climate prediction and carbon cycle assessment. To ensure their reliability, it is crucial to evaluate their performance in simulating key processes, such as evapotranspiration (ET) and gross primary...
Mucopolysaccharidosis type II is a lysosomal storage disorder caused by a deficiency of iduronate-2-sulfatase (IDS) and characterized by the accumulation of the primary storage substrate, glycosaminoglycans (GAGs). Understanding central nervous syste...
External Digital Elevation Models (DEMs) with different resolutions and accuracies cause different topographic residuals in differential interferograms of Multi-temporal InSAR (MTInSAR), especially for the phase-based StaMPS-PS. The PS selection and...
Rolling bearings often produce non-stationary signals that are easily obscured by noise, particularly in high-noise environments, making fault detection a challenging task. To address this challenge, a novel fault diagnosis approach based on the Kolm...
Morquio syndrome (mucopolysaccharidosis IV/MPS IV) is a genetic disorder leading to skeletal abnormalities and gait deviations. Research on the gait patterns and lower extremity physical characteristics associated with skeletal dysplasia in children...
Among C60’s diverse functionalities, its potential application in CO2 sequestration has gained increasing interest. However, the processes involved are sensitive to the molecule’s electronic structure, aspects of which remain debated and...
Wall-shear stress results from the relative motion of a fluid over a body surface as a consequence of the no-slip condition of the fluid in the vicinity of the wall. To determine the two-dimensional wall-shear stress distribution is of utter importan...
The growing adoption of supercomputers across various scientific disciplines, particularly by researchers without a background in computer science, has intensified the demand for parallel applications. These applications are typically developed using...
High-performance computing (HPC) and its supercomputers are essential for solving the most difficult issues in many scientific computing domains. The proliferation of computational resources utilized by HPC systems has resulted in an increase in the...
Due to its Lagrangian nature, Smoothed Particle Hydrodynamics (SPH) has been used to solve a variety of fluid-dynamic processes with highly nonlinear deformation such as debris flows, wave breaking and impact, multi-phase mixing processes, jet impact...
Cellulases are a class of enzymes of great industrial interest that present several strategic applications. However, the high cost of enzyme production, coupled with the instabilities and complexities of proteins required for hydrolytic processes, st...
In this paper, a new beamforming technique for planar two-dimensional arrays is proposed for optimizing the sidelobe levels (SLLs) by using recursive multibeam pattern subtraction (MPS) technique. The proposed MPS beamformer is demonstrated and its c...
Background: mpMRI assesses prostate lesions through their PI-RADS score. The primary goal of this prospective study was to demonstrate the correlation of PI-RADS v2 score and the volume of a lesion with the presence and clinical significance of prost...
The synergistic impact of microplastics (MPs) and organic pollutants remains poorly understood in the marine environment. This study aimed to assess the toxicity of polypropylene microplastics (PS) and/or di-(2-ethylhexyl) phthalate (DEHP) on marine...
Neonicotinoid resistance is increasingly prevalent in the agricultural pest Myzus persicae. Lipids play a critical role in insect defense systems, but their contribution to insect neonicotinoid resistance is disregarded. We conducted metabolomics and...
The resistance plasmid pUO-StVR2, derived from virulence plasmid pSLT, is widespread in clinical isolates of Salmonella enterica serovar Typhimurium recovered in Spain and other European countries. pUO-StVR2 carries several genes encoding a FetMP-Fls...
Parametric decay instability (PDI) generated in milliseconds is an important physical phenomenon in ionospheric heating. Usually, numerical simulations are used to study PDI mechanisms. They can intuitively investigate the generation and development...
Microplastics (MPs) have received increasing attention in the last decade and are now considered among the most concerning emerging pollutants in natural environments. Here, the current knowledge on microplastic ingestion by wild freshwater fish is r...
Compared with the finite element method (FEM), the meshfree smoothed point interpolation method (SPIM) has a more accurate stiffness and is not sensitive to mesh distortion, which has high potential in solving engineering problems. In this study, an...
24 May 2018
Solute transport modeling resolves advection, dispersion, and chemical reactions in groundwater systems with its accuracy depending on the resolution of domain at all scales, thus the computational efficiency of a simulator becomes a bottleneck for t...
While hair shafts are a common evidence type in forensic cases, they are often excluded from DNA analysis due to their limited DNA quantity and quality. Mitochondrial (mt) DNA sequencing is the method of choice when working with rootless hair shaft f...
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