Systemic Lupus Erythematosus: Current Trends and Therapeutic Innovations
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Immunology".
Deadline for manuscript submissions: 28 August 2025 | Viewed by 118
Special Issue Editor
Interests: systemic lupus erythematosus; rheumatic diseases; antiphospholipid syndrome; immune-mediated disease
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can affect any organ in the body, with the skin, joints, blood cells, kidney, lungs, heart, and central nervous system being more frequently involved. As with other autoimmune diseases, the pathogenesis of SLE relies on an anomaly in the immune system, where it is not capable of recognizing the body’s own antigens and attacks a patient’s cells.
SLE diagnosis is based on an array of clinical symptoms (e.g., arthralgia, shortness of breath, and tiredness) and signs (e.g., fever, joint edema and inflammation, and pleural effusion), and laboratory tests (blood count, renal function parameters, and proteinuria), along with non-specific and specific auto-antibodies, radiological tests, and histological exams (especially for kidney involvement). Meanwhile, other diseases should be ruled out. Diagnosis is not always straightforward, due to the diversity of clinical manifestations, which not always appear in the same way and at the same time, and sometimes it is possible after many years of follow-up.
The JCM is pleased to announce a Special Issue called “Systemic Lupus Erythematosus: Current Trends and Therapeutic Innovations”, which aims to provide an overview of current and new knowledge on the clinical features, diagnostic tools, treatment strategies (with a particular focus on new targeted therapies), biomarkers, and long-term outcomes of SLE.
Dr. Giuseppe Barilaro
Guest Editor
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Keywords
- systemic lupus erythematosus
- autoantibodies
- biomarkers
- therapeutic drugs
- lupus nephritis
- quality of life
- new treatment strategies
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