With the completion of the Human Genome Project, bioscience has entered into the era of the genome and proteome. Therefore, protein–protein interactions (PPIs) research is becoming more and more important. Life activities and the protein–protein inte...
Determining the complex relationships between diseases, polymorphisms in human genes and environmental factors is challenging. Multifactor dimensionality reduction (MDR) has been proven to be capable of effectively detecting the statistical patterns...
To address the imbalance between user evaluation noise and algorithmic autonomy in Interactive Evolutionary Design (IED), this study proposes an optimization method integrating subjective and objective weights to alleviate user fatigue and enhance ev...
Accurate tumor segmentation is important for aided diagnosis using breast ultrasound. Interactive segmentation methods can obtain highly accurate results by continuously optimizing the segmentation result via user interactions. However, traditional i...
Spatial heterogeneity patterns in cities are an essential topic in geographic research and urban planning. This paper analyzes the spatial heterogeneity of places and reflects on the urban structure in cites based on spatial interaction networks. To...
13 August 2024
This study provides additional context to the literature regarding the social inequities that impact birth outcomes in Virginia using a decision tree analysis. Chi-squared automatic interaction detection data analysis (CHAID) was performed using data...
During the process of maneuvering target tracking, the measurement may be disturbed by outliers, which leads to a decrease in the state estimation performance of the classic interacting multiple-model (IMM) filter. To solve this problem, a weighted m...
Energy intense nature of cement kiln demands optimal operation to minimize the energy requirement. Optimal control of cement kiln is achieved by proper tuning of the model predictive controller (MPC), which is addressed in this work. Genetic algorith...
Soybean hundred seed weight (HSW) is a complex quantitative trait affected by multiple genes and environmental factors. To date, a large number of quantitative trait nucleotides (QTNs) have been reported, but less information on QTN-by-environment in...
Due to the emergence of new big data technology, mobility data such as flows between origin and destination areas have increasingly become more available, cheaper, and faster. These improvements to data infrastructure have boosted spatial and tempora...
Predicting ncRNA–protein interactions (NPIs) is essential for understanding regulatory roles in cellular processes and disease mechanisms, yet experimental methods are costly and time-consuming. In this study, we propose NPI-WGNN, a novel weigh...
To reveal the regulatory effects of nitrogen and phosphorus interactions on grain-filling- and starch-synthesis-related enzymes, and grain weight of superior grains (SGs) and inferior grains (IGs) and taste quality, the japonica rice cultivar Shennon...
Correlations between exchange rates are valuable for illuminating the dynamics of international trade and the financial dynamics of countries. This paper explores the changing interactions of the US foreign exchange market based on detrended cross-co...
Proteins are vital for the significant cellular activities of living organisms. However, not all of them are essential. Identifying essential proteins through different biological experiments is relatively more laborious and time-consuming than the c...
18 August 2014
Weight gain is often associated with smoking cessation and may discourage smokers from quitting. This study estimated the weight gained one year after smoking cessation and examined the risk factors associated with weight gain in order to identify s...
Detecting high-order epistasis in genome-wide association studies (GWASs) is of importance when characterizing complex human diseases. However, the enormous numbers of possible single-nucleotide polymorphism (SNP) combinations and the diversity among...
(1) Background: Childhood rapid weight gain during development has been postulated as a predictor of obesity. The objective of this study was to investigate the effect of single nucleotide polymorphisms (SNPs) on the annual weight gain and height gro...
Considering the prerequisite need for a protected e-commerce platform, absence of haptic interaction in head-mounted displays (HMD), and exploitation of faster communication technology, this research work aims to present an amended version of the tel...
To gain insight into two different plant strategies (hyperaccumulation and phytostabilization) for managing heavy metals, we conducted a network based functional enrichment analysis. Protein-protein interactions of A. halleri root and shoot were deri...
Few-shot object detection suffers from limited annotations, redundant background interference, insufficient feature interaction, and severe sample imbalance. Existing meta-learning-based methods extract class prototypes from support images but often...
Attachment theory posits that patterns of interaction derived from the attachment system provide a starting point for understanding how people both receive and provide care. Extending this theory to human-animal interactions provides insights into ho...
The goal of the breeding process is to obtain new genotypes with traits improved over the parental forms. Parameters related to the additive effect of genes as well as their interactions (such as epistasis of gene–by–gene interaction effe...
Visual-based human interactive behavior recognition is a challenging research topic in computer vision. There exist some important problems in the current interaction recognition algorithms, such as very complex feature representation and inaccurate...
The rapid rise of obesity during the past decades has coincided with a profound shift of our living environment, including unhealthy dietary patterns, a sedentary lifestyle, and physical inactivity. Genetic predisposition to obesity may have interact...
Spatial-interaction networks are an important factor in geography that could help in the exploration of both human spatial-temporal behavior and the structure of urban areas. This paper analyzes changes in the spatio-temporal characteristics of the S...
RNA has emerged as a critical drug target, and accurate prediction of its binding affinity with small molecules is essential for the design and screening of RNA-targeted therapeutics. Although current deep learning methods have achieved progress in p...
It was reported that temperature affects the distribution of Wolbachia in the host, but only a few papers reported the effect of the interaction between high temperature and Wolbachia on the biological characteristic of the host. Here, we set four tr...
Large-scale vegetation restoration has caused complex changes in ecosystem service (i.e., ES) interactions. However, current analysis on the spatial interactions of ESs and their driving mechanisms remains deficient, limiting the adaptive management...
The combination of heavy metals and extracellular polymeric substances (EPSs) affects the distribution of heavy metals in microbial aggregates, soil, and aquatic systems. This paper aimed to explore the binding mechanisms of EPSs of different molecul...
The interplay patterns of amino acid residues are pivotal in determining the tertiary structure and flexibility of proteins, which in turn are intricately linked to their functionality and interactions with other molecules. Here, we introduce ARIP, a...
The interaction-based hazard index (HIINT), a mixtures approach to characterizing toxicologic interactions, is demonstrated and evaluated by statistically analyzing data on four regulated trihalomethanes (THMs). These THMs were the subject of a multi...
Water inrush in karst tunnels will cause casualties and economic losses. Thus, it is significant to objectively assess the water inrush risk level and adopt valid preventive measures to reduce losses from this disaster. The relationship between the f...
To scientifically enhance user perception in decision-making for designing interactive spaces in schools for children with intellectual disabilities, we propose an innovative design model that integrates the Kano model, Analytic Hierarchy Process (AH...
To examine the interactions between two binder systems—hydroxyl-terminated polybutadiene (HTPB) and hydroxyl-terminated block copolyether prepolymer (HTPE)—as well as between these binders and ammonium perchlorate (AP) at various temperat...
Maize/peanut intercropping is practiced widely to increase land productivity and considered a sustainable way for using and saving resources through peanut’s complementary N source via biological N2 fixation. Our study aims to understand how ma...
The saturated hydraulic conductivity (Ks) of soil is a key parameter governing ecohydrological processes in forest ecosystems. However, quantifying the independent contribution of dominant tree species to Ks remains challenging due to environmental c...
We report the synthesis of three (3) linear triblock terpolymers, two (2) of the ABC type and one (1) of the BAC type, where A, B and C correspond to three chemically incompatible blocks such as polystyrene (PS), poly(butadiene) of exclusively (~100%...
Aptamers offer several advantages over antibodies. However, to ensure high affinity and specificity, a better understanding of the interactions between the nucleic-acid-based aptamers and their targets is mandatory. Therefore, we investigated the inf...
Earthen dams with greater fines are more susceptible to failure from the piping. This study employed the coupled computational fluid dynamics (CFD)-discrete element method (DEM) to investigate the impact of the piping erosion process. Results display...
In the Taihang Mountain Tourism Development Plan (2020–2035), the Taihang Mountain Expressway is included in the construction of the National Tourism Scenic Road around Taihang Mountain to promote the integrated development of regional transpor...
Protein-protein interactions (PPIs) play important roles in various aspects of the structural and functional organization of cells; thus, detecting PPIs is one of the most important issues in current molecular biology. Although much effort has been d...
Glucagon-like peptide-1 receptor (GLP1R) agonists, such as semaglutide, are used for treating type 2 diabetes mellitus and promoting weight loss. This study investigates genetic and molecular mechanisms underlying GLP1R activation using a novel in si...
The band shapes and band positions of near-infrared (NIR) and Raman spectra change depending on the concentrations of specific chemical functionalities in a multicomponent system. To elucidate these effects in more detail and clarify their impact on...
The yield of flowering crops depends on multiple factors, with pollination and the availability of nutrients being particularly crucial. However, fewer studies have explored the combined effects of nutrients and insect-mediated pollination on onions...
Assessment of water resource spatial equilibrium (WRSE) is crucial for regional sustainable development, yet traditional methods always face difficulties in quantifying systemic differences and resolving their internal uncertainties. Accordingly, thi...
The seed yield of 28 bean (Phaseolus vulgaris) lines from different crosses and two check cultivars was evaluated under rainfed conditions in two sites in North-Central Mexico. The aim was to identify high-yielding lines with low genotype–envir...
Studies on the interactions between single nucleotide polymorphisms (SNPs) and macronutrient consumption on weight loss are rare and heterogeneous. This review aimed to conduct a systematic literature search to investigate genotype–diet interac...
As the core technology of artificial intelligence, salient object detection (SOD) is an important approach to improve the analysis efficiency of remote sensing images by intelligently identifying key areas in images. However, existing methods that re...
An imbalance between production and excretion of amyloid β peptide (Aβ) in the brain tissues of Alzheimer’s disease (AD) patients leads to Aβ accumulation and the formation of noxious Aβ oligomers/plaques. A promising approa...
This pilot study investigates the relationship between gesture intuitiveness and muscle network efficiency in human–machine interactions (HMIs), emphasizing objective neurophysiological measures. EMG signals from 16 muscles were analyzed to con...
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