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40,233 Results Found

  • Article
  • Open Access
11 Citations
6,323 Views
25 Pages

1 October 2015

Prior exploration is an instructional strategy that has improved performance and understanding in system-dynamics-based simulators, but only to a limited degree. This study investigates whether model transparency, that is, showing users the internal...

  • Article
  • Open Access
1 Citations
3,373 Views
16 Pages

11 September 2024

Solving problems in a technical system usually requires people to understand its functioning on different levels of abstraction (i.e., goals, functions, components, characteristics) that are connected via means–ends links. We combined this abst...

  • Article
  • Open Access
2,147 Views
15 Pages

Parasympathetic Nervous System Functioning Moderates the Associations between Callous-Unemotional Traits and Emotion Understanding Difficulties in Late Childhood

  • Sarah F. Lynch,
  • Samantha Perlstein,
  • Cora Ordway,
  • Callie Jones,
  • Hanna Lembcke,
  • Rebecca Waller and
  • Nicholas J. Wagner

2 February 2024

Background: Callous-unemotional (CU) traits are characterized by low empathy, guilt, and prosociality, putting children at risk for lifespan antisocial behavior. Elevated CU traits have been linked separately to difficulties with emotion understandin...

  • Article
  • Open Access
5 Citations
5,311 Views
18 Pages

15 February 2022

Successful applications of deep learning technologies in the natural language processing domain have improved text-based intent classifications. However, in practical spoken dialogue applications, the users’ articulation styles and background n...

  • Article
  • Open Access
8 Citations
3,809 Views
14 Pages

Data Engineering for Affective Understanding Systems

  • Nuha El-Khalili,
  • May Alnashashibi,
  • Wael Hadi,
  • Abed Alkarim Banna and
  • Ghassan Issa

18 April 2019

Affective understanding is an area of affective computing which is concerned with advancing the ability of a computer to understand the affective state of its user. This area continues to receive attention in order to improve the human-computer inter...

  • Article
  • Open Access
4 Citations
6,933 Views
10 Pages

20 October 2014

Different accounts have been given in order to face the problem of the emergence of musical consonance and dissonance. Getting a more adequate comprehension of such phenomenology may require a systemic view to integrate such multidimensionality into...

  • Perspective
  • Open Access
3 Citations
2,415 Views
11 Pages

28 September 2023

Renewable, decentralised, and citizen-centred energy paradigms have emerged as feasible and reliable alternatives to the traditional centralised fossil-based infrastructure. In this scenario, energy storage systems (ESSs) are enabling technologies to...

  • Article
  • Open Access
1,946 Views
19 Pages

23 November 2023

Symbolic semantic understanding of staff images is an important technological support to achieve “intelligent score flipping”. Due to the complex composition of staff symbols and the strong semantic correlation between symbol spaces, it i...

  • Essay
  • Open Access
4 Citations
6,735 Views
11 Pages

1 April 2015

Understanding the molecular impact of lifestyle factors has never been so important; a period in time where there are so many adults above retirement age has been previously unknown. As a species, our life expectancy is increasing yet the period of o...

  • Review
  • Open Access
24 Citations
5,453 Views
12 Pages

The Ocular Glymphatic System—Current Understanding and Future Perspectives

  • Christine Delle,
  • Xiaowei Wang and
  • Maiken Nedergaard

The ocular glymphatic system subserves the bidirectional polarized fluid transport in the optic nerve, whereby cerebrospinal fluid from the brain is directed along periarterial spaces towards the eye, and fluid from the retina is directed along periv...

  • Review
  • Open Access
48 Citations
12,794 Views
54 Pages

Computational Strategies for a System-Level Understanding of Metabolism

  • Paolo Cazzaniga,
  • Chiara Damiani,
  • Daniela Besozzi,
  • Riccardo Colombo,
  • Marco S. Nobile,
  • Daniela Gaglio,
  • Dario Pescini,
  • Sara Molinari,
  • Giancarlo Mauri and
  • Marco Vanoni
  • + 1 author

24 November 2014

Cell metabolism is the biochemical machinery that provides energy and building blocks to sustain life. Understanding its fine regulation is of pivotal relevance in several fields, from metabolic engineering applications to the treatment of metabolic...

  • Article
  • Open Access
17 Citations
3,895 Views
18 Pages

An Approach for Systems-Level Understanding of Prostate Cancer from High-Throughput Data Integration to Pathway Modeling and Simulation

  • Mohammad Mobashir,
  • S. Pauliina Turunen,
  • Mohammad Asrar Izhari,
  • Ibraheem Mohammed Ashankyty,
  • Thomas Helleday and
  • Kaisa Lehti

19 December 2022

To understand complex diseases, high-throughput data are generated at large and multiple levels. However, extracting meaningful information from large datasets for comprehensive understanding of cell phenotypes and disease pathophysiology remains a m...

  • Review
  • Open Access
5 Citations
4,942 Views
21 Pages

Current Understanding Regarding the Glioma Microenvironment and Impact of the Immune System

  • Enes Demir,
  • Deondra Montgomery,
  • Ammar Saloum,
  • Nasser Yaghi and
  • Michael Karsy

High-grade gliomas are aggressive, primary, central nervous system tumors with low survival rates due to recurrence and resistance to current therapy models. Recent studies have highlighted the importance between the interaction of glioma cancer cell...

  • Article
  • Open Access
8 Citations
2,891 Views
27 Pages

8 February 2020

The cyber processing layer of smart systems based on a cognitive dynamic system (CDS) can be a good solution for better decision making and situation understanding in non-Gaussian and nonlinear environments (NGNLE). The NGNLE situation understanding...

  • Review
  • Open Access
26 Citations
7,326 Views
22 Pages

Understanding the Current Energy Paradigm and Energy System Models for More Sustainable Energy System Development

  • Nathalie Spittler,
  • Ganna Gladkykh,
  • Arnaud Diemer and
  • Brynhildur Davidsdottir

25 April 2019

This study contributes to a better understanding of where to place different energy modelling tools and support better decision-making related to the sustainable development of energy systems. It is argued that through the connection of the energy fi...

  • Review
  • Open Access
1,547 Views
17 Pages

Hepatic Lymphatic System and Its Current Understanding in Liver-Related Pathophysiology

  • Jingjing Pang,
  • Jianan Zhao,
  • Liam Flynn,
  • Juncheng Wei,
  • Long Nguyen Hoang Do,
  • Esteban Delgado and
  • Xiaolei Liu

The hepatic lymphatic system, long underappreciated, plays a critical role in liver physiology by maintaining interstitial fluid balance, removing metabolic waste, and facilitating immune surveillance. Emerging evidence indicates that lymphatic dysfu...

  • Article
  • Open Access
39 Citations
8,092 Views
20 Pages

The adoption of the global positioning system (GPS) within the marine industry has revolutionized the marine operations by condensing the navigation of a vessel into an integrated bridge system (IBS). An IBS acts as the main command and control of a...

  • Abstract
  • Open Access
1 Citations
1,435 Views
2 Pages

Understanding the Complexity of the Food System: Differences and Commonalities between Two Optimization Models

  • Samantha N. Heerschop,
  • Renee P. M. Cardinaals,
  • Sander Biesbroek,
  • Argyris Kanellopoulos,
  • Johanna M. Geleijnse,
  • Pieter van ‘t Veer and
  • Hannah H. E. van Zanten

Background and objectives: There is a compelling need for a more sustainable food system because of climate change and contemporary Western diets, which pose a threat to human and planetary health. The food system is a social–ecological system,...

  • Article
  • Open Access
12 Citations
6,075 Views
17 Pages

A Comprehensive Analysis of Sensitivity in Simulation Models for Enhanced System Understanding and Optimisation

  • Patrik Grznár,
  • Milan Gregor,
  • Štefan Mozol,
  • Lucia Mozolová,
  • Henrich Krump,
  • Marek Mizerák and
  • Jozef Trojan

1 April 2024

This article delves into sensitivity analysis within simulation models of real systems, focusing on the impact of variability in independent input factors (x) on dependent system outputs (y). It discusses linear and nonlinear regression to analyse an...

  • Review
  • Open Access
25 Citations
6,963 Views
9 Pages

11 April 2021

This qualitative review on rotavirus infection and its complications in the central nervous system (CNS) aims to understand the gut–brain mechanisms that give rise to CNS driven symptoms such as vomiting, fever, feelings of sickness, convulsions, enc...

  • Article
  • Open Access
389 Views
23 Pages

Scene Understanding System of Underground Pipeline Corridors Under Characteristic Degradation Conditions

  • Jing Wang,
  • Ruiyao Xing,
  • Meng Zhou,
  • Jingbang Xu,
  • Xiaoping Zhang and
  • Shuang Ju

25 December 2025

Accurate scene understanding is crucial for the safe and stable operation of underground utility tunnel inspections. Addressing the characteristics of low-light environments, this paper proposes an object recognition method based on low-light enhance...

  • Article
  • Open Access
1 Citations
2,967 Views
18 Pages

Helping the sick and protecting the vulnerable has long been the credo of the health profession. In response to the coronavirus-disease-2019 (COVID-19 pandemic), hospitals and healthcare institutions have rapidly employed public health measures to mi...

  • Review
  • Open Access
211 Citations
27,629 Views
22 Pages

14 November 2019

Venoms are one of the most convergent of animal traits known, and encompass a much greater taxonomic and functional diversity than is commonly appreciated. This knowledge gap limits the potential of venom as a model trait in evolutionary biology. Her...

  • Review
  • Open Access
13 Citations
4,597 Views
23 Pages

Understanding In Vitro Tissue Culture-Induced Variation Phenomenon in Microspore System

  • Piotr Tomasz Bednarek,
  • Katarzyna Anna Pachota,
  • Wioletta Monika Dynkowska,
  • Joanna Machczyńska and
  • Renata Orłowska

In vitro tissue culture plant regeneration is a complicated process that requires stressful conditions affecting the cell functioning at multiple levels, including signaling pathways, transcriptome functioning, the interaction between cellular organe...

  • Review
  • Open Access
5 Citations
5,181 Views
15 Pages

A Switching Hybrid Dynamical System: Toward Understanding Complex Interpersonal Behavior

  • Yuji Yamamoto,
  • Akifumi Kijima,
  • Motoki Okumura,
  • Keiko Yokoyama and
  • Kazutoshi Gohara

22 December 2018

Complex human behavior, including interlimb and interpersonal coordination, has been studied from a dynamical system perspective. We review the applications of a dynamical system approach to a sporting activity, which includes continuous, discrete, a...

  • Review
  • Open Access
8 Citations
9,443 Views
14 Pages

Functional Near-Infrared Spectrometry as a Useful Diagnostic Tool for Understanding the Visual System: A Review

  • Kelly Acuña,
  • Rishav Sapahia,
  • Irene Newman Jiménez,
  • Michael Antonietti,
  • Ignacio Anzola,
  • Marvin Cruz,
  • Michael T. García,
  • Varun Krishnan,
  • Lynn A. Leveille and
  • Delia Cabrera DeBuc
  • + 3 authors

4 January 2024

This comprehensive review explores the role of Functional Near-Infrared Spectroscopy (fNIRS) in advancing our understanding of the visual system. Beginning with an introduction to fNIRS, we delve into its historical development, highlighting how this...

  • Article
  • Open Access
6 Citations
4,626 Views
21 Pages

Non-destructive testing (NDT) is a quality control measure designed to ensure the safety of products according to established variability thresholds. With the development of advanced technologies and a lack of formalised knowledge of the state-of-the...

  • Article
  • Open Access
2,784 Views
15 Pages

In this paper we apply our understanding of the radical enactivist agenda to the classic AI-hard problem of Natural Language Understanding. When Turing devised his famous test the assumption was that a computer could use language and the challenge wo...

  • Article
  • Open Access
19 Citations
7,508 Views
27 Pages

Vision-Language Models for Autonomous Driving: CLIP-Based Dynamic Scene Understanding

  • Mohammed Elhenawy,
  • Huthaifa I. Ashqar,
  • Andry Rakotonirainy,
  • Taqwa I. Alhadidi,
  • Ahmed Jaber and
  • Mohammad Abu Tami

Scene understanding is essential for enhancing driver safety, generating human-centric explanations for Automated Vehicle (AV) decisions, and leveraging Artificial Intelligence (AI) for retrospective driving video analysis. This study developed a dyn...

  • Article
  • Open Access
1 Citations
7,562 Views
12 Pages

1 December 2001

The cardinality of the class, C , of complex intelligent systems, i.e., systems of intelligent systems and their resources, is steadily increasing. Such an increase, whether designed, sometimes changes significantly and fundamentally, the structure o...

  • Review
  • Open Access
49 Citations
11,924 Views
29 Pages

Understanding the Intricate Web of Phytohormone Signalling in Modulating Root System Architecture

  • Manvi Sharma,
  • Dhriti Singh,
  • Harshita B. Saksena,
  • Mohan Sharma,
  • Archna Tiwari,
  • Prakhar Awasthi,
  • Halidev Krishna Botta,
  • Brihaspati Narayan Shukla and
  • Ashverya Laxmi

Root system architecture (RSA) is an important developmental and agronomic trait that is regulated by various physical factors such as nutrients, water, microbes, gravity, and soil compaction as well as hormone-mediated pathways. Phytohormones act as...

  • Article
  • Open Access
3 Citations
3,166 Views
29 Pages

23 March 2025

Model-Based Systems Engineering (MBSE) prioritizes system design through models rather than documents, and it is implemented with the Systems Modeling Language (SysML), which is the state-of-the-art language in academia and industry. Virtual Reality...

  • Feature Paper
  • Review
  • Open Access
2 Citations
2,812 Views
14 Pages

29 January 2024

Despite their diminutive neural systems, insects exhibit sophisticated adaptive behaviors in diverse environments. An insect receives various environmental stimuli through its sensory organs and selectively and rapidly integrates them to produce an a...

  • Article
  • Open Access
7 Citations
10,748 Views
25 Pages

Understanding chemical models can be challenging for many university students studying chemistry. This study analysed students’ understanding of molecular structures using the Lewis structure as a model, and examined what hinders their understanding....

  • Article
  • Open Access
117 Citations
48,206 Views
23 Pages

This paper summarizes current understanding of the processes that determine the dynamics of the subsea permafrost–hydrate system existing in the largest, shallowest shelf in the Arctic Ocean; the East Siberian Arctic Shelf (ESAS). We review key...

  • Article
  • Open Access
19 Citations
14,502 Views
31 Pages

Augmented Robotics Dialog System for Enhancing Human–Robot Interaction

  • Fernando Alonso-Martín,
  • Aĺvaro Castro-González,
  • Francisco Javier Fernandez de Gorostiza Luengo and
  • Miguel Ángel Salichs

3 July 2015

Augmented reality, augmented television and second screen are cutting edge technologies that provide end users extra and enhanced information related to certain events in real time. This enriched information helps users better understand such events,...

  • Article
  • Open Access
3 Citations
2,803 Views
15 Pages

A transient inline spiking system is a promising tool for evaluating the performance of a virus filter in continuous operation. For better implementation of the system, we performed a systematic analysis to understand the residence time distribution...

  • Article
  • Open Access
9 Citations
6,667 Views
23 Pages

In this work, we present a novel approach to understand the quality of public transit system in resource constrained regions using user-generated contents. With growing urban population, it is getting difficult to manage travel demand in an effective...

  • Article
  • Open Access
4 Citations
5,658 Views
11 Pages

Natural Language Understanding (NLU) systems are essential components in many industry conversational artificial intelligence applications. There are strong incentives to develop a good NLU capability in such systems, both to improve the user experie...

  • Article
  • Open Access
693 Views
19 Pages

24 November 2025

The cooperative operation of multiple Unmanned Aerial Vehicles (multi-UAV) is emerging as a pivotal trend in future complex autonomous systems. To enable accurate mission understanding and efficient collaboration among UAVs in complex, dynamic, and u...

  • Article
  • Open Access
6 Citations
5,150 Views
26 Pages

Understanding the Complexity of Water Supply System Governance: A Proposal for a Methodological Framework

  • Fernando Gumeta-Gómez,
  • Andrea Sáenz-Arroyo,
  • Gustavo Hinojosa-Arango,
  • Claudia Monzón-Alvarado,
  • Maria Azahara Mesa-Jurado and
  • Dolores Molina-Rosales

14 October 2021

The question of how the complexity of water governance may be understood beyond a heuristic concept remains unanswered. In this paper, we propose a Water Governance Complexity Framework to address the complexity of water governance. Through a literat...

  • Article
  • Open Access
5 Citations
3,348 Views
18 Pages

Understanding Hydrologic, Human, and Climate System Feedback Loops: Results of a Participatory Modeling Workshop

  • Jefferson K. Rajah,
  • Ashley E. P. Atkins,
  • Christine Tang,
  • Kathelijne Bax,
  • Brooke Wilkerson,
  • Alexander G. Fernald and
  • Saeed P. Langarudi

24 January 2024

Groundwater depletion threatens global freshwater resources, necessitating urgent water management and policies to meet current and future needs. However, existing data-intensive approaches to assessments do not fully account for the complex human, c...

  • Article
  • Open Access
2 Citations
2,728 Views
12 Pages

The Performance Management and Development System (PMDS) is an essential asset in aligning the strategic objectives of both the National and Provincial departments of health with the individual targets and Key Responsibility Areas (KRAs) of the indiv...

  • Article
  • Open Access
21 Citations
6,834 Views
21 Pages

Interactive Knowledge Co-Production and Integration for Healthy Urban Development

  • Rehana Shrestha,
  • Heike Köckler,
  • Johannes Flacke,
  • Javier Martinez and
  • Martin Van Maarseveen

26 October 2017

The transformation of cities towards healthy urban living environments for all is a challenge that needs to be addressed through collaboration of all relevant sectors in a transdisciplinary research processes. This paper reports on the design and sho...

  • Article
  • Open Access
2 Citations
4,029 Views
16 Pages

Human Resource Information Systems (HRISs) have become integral to contemporary organizational life, yet their successful adoption remains uneven and poorly understood. Existing models often focus on cognitive or technical determinants, overlooking h...

  • Article
  • Open Access
1,385 Views
27 Pages

Telemedicine in emergency contexts presents unique challenges, particularly in multilingual and low-resource settings where accurate, clinical understanding and triage decision support are critical. This paper introduces TriagE-NLU, a novel multiling...

  • Article
  • Open Access
1,199 Views
31 Pages

From Games to Understanding: Semantrix as a Testbed for Advancing Semantics in Human–Computer Interaction with Transformers

  • Javier Sevilla-Salcedo,
  • José Carlos Castillo Montoya,
  • Álvaro Castro-González and
  • Miguel A. Salichs

31 August 2025

Despite rapid progress in natural language processing, current interactive AI systems continue to struggle with interpreting ambiguous, idiomatic, and contextually rich human language, a barrier to natural human–computer interaction. Many deplo...

  • Review
  • Open Access
6 Citations
6,450 Views
26 Pages

16 October 2024

Autonomous vehicles (AVs) represent a transformative innovation in transportation, promising enhanced safety, efficiency, and sustainability. Despite these promises, achieving robustness, reliability, and adherence to ethical standards in AV systems...

  • Article
  • Open Access
17 Citations
6,980 Views
35 Pages

10 January 2023

To meet the sustainability challenges in the 21st century, students need to develop a unique human learning capacity for creativity, responsibility, adaptation, meaningfulness, and lifelong learning. Furthermore, current changes in the societal envir...

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