1,571 Results Found

Literature on the trends of health tourism development has proven that it is becoming one of the most important tourism activities. With the growing popularity of this form of tourism, the structure of the needs of tourists and spa patients is simult...

The article deals with the financing of spa undertakings through the health insurance system. The analysis is based on the financial statements of 28 spa undertakings operating in the Slovak Republic, their contracts with the individual health insura...

The present paper consists of a co-word analysis of the previous research in the medical spa field published in the Web Science Core Collection database. The study’s main purpose is to identify the past trends in the medical spa field from the touris...

Health tourism, including spa-based treatments, is an important segment of global travel, and its growth reflects increasing demand for experiences that combine physical well-being with contact with nature. Polish health spa resorts are rich in balne...

Health tourism is booming all over the world, and thermal spa tourism in Spain is a type of tourism aimed at integrating with nature, achieving sustainable development. In general, its facilities are located in areas specially protected by environmen...

Recent decades have witnessed an increased volume of studies investigating the spa tourism sector. There has, however, been an absence of studies evaluating the relationship between corporate social responsibility (CSR) and spa competitiveness, as we...

Swimming and bathing environments play a crucial role in promoting health, well-being, and social inclusion. The recreational use of water bodies for play and leisure activities presents a unique opportunity for interdisciplinary water research, enab...

Land-use change associated with scattered (isolated) housing in the countryside remains largely underestimated in conventional European land-use datasets due to spatial resolution and minimum mapping unit constraints. This study quantifies low-densit...

Background: Human SP-A1 and SP-A2, encoded by SFTPA1 and SFTPA2, and their genetic variants differentially impact alveolar macrophage (AM) functions and regulation, including the miRNome. We investigated whether miRNome differences previously observe...

This study develops the BIO-SPA Certification Model, a novel framework for evaluating the spatial organisation and biophilic design performance of spa centres within hotel and resort facilities. The research focuses on spa environments in five-star a...

Most spas are surrounded by beautiful natural environments, so these facilities contribute to sustainable economic development and their guests are national and local tourists with a high average stay. This study has the objective of analyzing the fa...

The present article includes descriptive research about how water resources in Romanian medical spas could be better promoted to increase their visibility. Romania is one of the European countries with impressive potential in terms of balneology, hav...

Spa therapy is a medical treatment based on the use of natural mineral water. In France, spa therapy is delivered in spa care facilities (SCF) involving the intervention of several actors (stakeholders). Spa doctors are key stakeholders as they presc...

Natural healing resources in the form of mineral and thermal waters and climatic conditions, together with a rich history and modern medical procedures, rank Slovakia among the important European countries in the field of spas. At the same time, spa...

This study sought to obtain conglomerates of spa-goers in Andalusia, Spain, based on a survey of 10 spas’ users. The data from 725 valid survey questionnaires were analysed using a quantitative approach. The results show that 44.6% of users are betwe...

SPAs (suppressors of phyA-105) are key modulators of photomorphogenesis that regulate diverse aspects of plant growth. While the role of SPA proteins in Arabidopsis photomorphogenesis is well-characterized, the functions of their maize (Zea mays L.)...

Water is the common thread and attraction factor of the tourism facilities called “spas”, which are part of health and beauty services. Spa use is currently experiencing a boom that reflects changes in populations, such as an increase in economic wel...

The Vâlcea Subcarpathians, known for their wealth of natural resources and their spa tradition, are distinguished by renowned spa resorts such as Băile Olănești, Călimănești, Ocnele Mari and Băile Govora. Thes...

The main objective of this research was to present Serbia as a destination for wellness and spa tourism, bearing in mind the fact that there are about 1000 springs in this area with a potential for tourism. Then again, since there are only about 40 a...

Spa tourism is considered one of the most important segments of the $639 billion wellness market. The literature refers to two types of spa tourists: wellness tourists and healthcare/medical tourists. However, virtually no studies have compared spa c...

A crucial factor in shaping the character of a spa and wellness hotel’s character is the design and functionality of the recreational area. This element is linked to other areas in the hotel, such as dining, accommodation, and conference facili...

The tourism sector has witnessed continuous development over the last few decades, overcoming various challenges and crises. This resilience underscores the remarkable diversity of managerial and entrepreneurial initiatives capable of meeting the eve...

Staphylococcus aureus bacteremia is one of the most frequent and severe bacterial infections worldwide. The increased incidence of S. aureus infections with a diverse pattern of S. aureus protein A (spa) types across different geographic regions is a...

Background: Rehabilitation-oriented therapy after a stroke must continue in various forms as a life-long effort. Aim: The study investigated the impact of spa rehabilitation on the quality of life and functional efficiency in patients after an ischem...

This paper presents a cluster analysis of 20 spa enterprises operating in Slovakia, based on key financial indicators for the years 2018 and 2023. A comparative time-based approach was adopted to capture changes in financial performance over time. Th...

There is a considerable debate in the literature regarding the real impact of tourism on the environment and human communities, specifically with respect to tourism’s openness to sustainable innovation. The way in which the different forms of t...

Spam reviews are increasingly appearing on the Internet to promote sales or defame competitors by misleading consumers with deceptive opinions. This paper proposes a co-training approach called CoSpa (Co-training for Spam review identification) to id...

Inflammation and oxidative stress plays an essential role in the pathophysiology of sepsis-associated acute kidney injury (AKI). SPA0355, a thiourea analogue, has been shown to display beneficial effects against a variety of inflammatory diseases ari...

SUPPRESSOR OF PHYA-105 (SPA) proteins bind the E3 ubiquitin ligase CONSTITUTIVELY PHOTOMORPHOGENIC 1 (COP1) and, within the COP1/SPA complex, repress light signaling in plants. For two decades, SPA proteins were regarded mainly as COP1 cofactors. Sin...

Background: Kivach Clinic has developed a special medical spa program to prevent aging-related conditions in metabolic, cardio-vascular, and neurological states. Spa programs modify diet, physical activity, and lymphatic drainage, as it deteriorates...

Natural spa springs are diffused all over the world and their use in pools is known since ancient times. This review underlines the cultural and social spa context focusing on hygiene issues, public health guidelines and emerging concerns regarding w...

This study investigates whether spa settlements can be analytically interpreted through a relational spascape framework that reveals structural and configurational patterns beyond conventional typological classifications. In the context of increasing...

COP1/SPA1 complex in Arabidopsis inhibits photomorphogenesis through the ubiquitination of multiple photo-responsive transcription factors in darkness, but such inhibiting function of COP1/SPA1 complex would be suppressed by cryptochromes in blue lig...

Bosnia and Herzegovina (B&H) possess many natural resources that can be exploited for the development of medical tourism. The offer of medical tourism in B&H is focused on spa tourism. B&H has 16 registered spa-centers offering different...

Spa tourism has undergone important changes in recent decades, actively embracing wellness and wellbeing. However, this transition is taking place in different ways in Europe, and this has led to varying perceptions of thermalism that have little to...

Background: The bacterial species S. aureus is the most common causative agent of mastitis in cows in most countries with a dairy industry. The prevalence of infection caused by S. aureus ranges from 2% to more than 50%, and it causes 10–12% of all c...

Paclitaxel (PTX) is one of the most efficient drugs for late-stage non-small cell lung cancer (NSCLC) patients. However, most patients gradually develop resistance to PTX with long-term treatments. The identification of new strategies to reverse PTX...

Given the various clinical manifestations that characterize Coronavirus Disease 2019 (COVID-19), the scientific community is constantly searching for biomarkers with prognostic value. Surfactant proteins A (SP-A) and D (SP-D) are collectins that play...

Starch and prolamin composition and content are important indexes for determining the processing and nutritional quality of wheat (Triticum aestivum L.) grains. Several transcription factors (TFs) regulate gene expression during starch and protein bi...

Erysipelothrix rhusiopathiae is a causative agent of erysipelas in animals and erysipeloid in humans. However, current information regarding E. rhusiopathiae pathogenesis remains limited. Previously, we identified two E. rhusiopathiae strains, SE38 a...

Spa therapy is known to improve quality of life and diminish pain. We assessed the efficacy (Fibromyalgia Impact Questionnaire-FIQ) and safety at 6 months of a fibromyalgia-specific therapeutic patient education (TPE) program added to fibromyalgia-sp...

The article presents the results of the analysis of the elements of business models of spa tourism enterprises in the context of the principles of sustainable development in tourism business. In the process of defining individual rules for tourist en...

Frailty is not limited to the elderly, as patients with rheumatic diseases can also experience this condition. The present scoping review aimed to investigate the possibility of using the health resort setting as an alternative location for managing...

108 isolates of Staphylococcus aureus, belonging to six large ribogroups according to the automated Ribo-Printer^® system, were studied with two highly used molecular methods for epidemiological studies, namely multi-locus sequence typing (MLST) a...

The COVID-19 pandemic has left behind mental health issues like anxiety, depression, and sleep disorders among survivors. This study assessed the efficacy of spa therapy in enhancing psychological well-being and sleep quality in individuals with chro...

Background: With limited pharmacological interventions, post-COVID-19 condition is a clinical challenge, and supplementary therapies are essential for symptom relief and enhancing quality of life (QoL). In our prospective observational study, we aime...

Consumer education, including nutrition education, understood as a process based on scientific principles, is becoming a very effective element in influencing the health of the population in the modern world. This work is based on direct research car...

Well-being tourism is a $639 billion market. Spa tourism is considered the most important segment within this market. The present study uses the Unified Theory of Acceptance and Use of Technology (UTAUT2) model to analyse tourists’ purchase int...

Co-enzyme nicotinamide adenine dinucleotide (NAD(H)) redox plays a key role in macrophage function. Surfactant protein (SP-) A modulates the functions of alveolar macrophages (AM) and ozone (O₃) exposure in the presence or absence of SP-A and reduces...

Health and spa tourism is a rapidly growing sector that merges traditional healing with modern innovations to meet increasingly diverse client needs. Understanding professionals’ perspectives is crucial for developing sustainable strategies tha...