The satellite–rocket separation shock environment involves transient structural responses during spacecraft release. Although its direct influence on the main structure of the satellite is limited, it can easily cause shock-sensitive precision...
The heat shock response is an evolutionarily conserved mechanism that protects cells or organisms from the harmful effects of various stressors such as heat, chemicals toxins, UV radiation, and oxidizing agents. The heat shock response triggers the e...
Stiffened plate structures widely used in military aircraft are frequently subjected to severe shock environments, such as those generated by gunfire or explosive blasts, which can significantly compromise the integrity and reliability of onboard equ...
An improved method based on the Hybrid Finite Element-Statistical Energy Analysis (FE-SEA) method and quasi-steady state theory is proposed to predict the response of spacecraft structure during the process of pyrotechnics separation. Firstly, the am...
The purpose of this study was to determine the effect of fatigue on impact shock wave attenuation and assess how human biomechanics relate to shock attenuation during running. In this paper, we propose a new methodology for the analysis of shock even...
Within the last two decades, there has been increasing evidence that heat-shock proteins can have a differential influence on the immune system. They can either provoke or ameliorate immune responses. This review focuses on outlining the stimulatory...
The heat shock response (HSR) is a conserved cellular mechanism critical for adaptation to environmental and physiological stressors, with broad implications for cell survival, immune responses, and cancer biology. While the HSR has been extensively...
This article explores systemic inflammatory response syndrome (SIRS), thromboinflammation, and septic shock in fetuses and neonates, offering a comprehensive examination of their pathophysiology, diagnostic criteria, and clinical implications. It ide...
In a warming world, mechanisms, such as the heat shock response, which plays a role in the recovery from or tolerance towards heat stress, are of increasing importance. Certain heat shock protein genes (hsps) have previously been shown to be highly i...
The Heat Shock Response (HSR) is a highly conserved genetic system charged with protecting the proteome in a wide range of organisms and species. Experiments since the early 1980s have elucidated key elements in these pathways and revealed a canonica...
MEMS suspended inductors are susceptible to deformation under external forces, which can lead to the degradation of their electrical properties. The mechanical response of the inductor to a shock load is usually solved by a numerical method, such as...
Underwater bottom-sitting shell structures face threats from underwater explosion shock waves. To investigate the damage characteristics and dynamic response of bottom-sitting shell structures under underwater explosion shock waves, three-dimensional...
Mitochondria are important organelles in eukaryotes and are involved in various metabolic processes. Mitochondrial proteotoxic stress triggers the mitochondrial unfolded protein response (UPRmt) to restore mitochondrial protein homeostasis and mainta...
The ability to gauge the surroundings and modulate gene expression accordingly is a crucial feature for the survival bacterial pathogens. In this respect, the heat-shock response, a universally conserved mechanism of protection, allows bacterial cell...
This paper presents a micromachined silicon resonant accelerometer based on electrostatic active damping control, which can improve the shock response performance of the accelerometer. In the accelerometer, an electrostatic active damping structure a...
Staphylococcal toxic shock syndrome (STSS) is a rare, yet potentially fatal disease caused by Staphylococcus aureus (S. aureus) enterotoxins, known as superantigens, which trigger an intense immune response. Our previous study demonstrated the protec...
Micro-electromechanical system (MEMS) suspended inductors have excellent radio-frequency (RF) performance, but poor mechanical properties. To improve their reliability, auxiliary pillars have been used. However, few studies have been carried out on t...
Repurposing approved and abandoned non-oncological drugs is an alternative developmental strategy for the identification of anticancer therapeutics that has recently attracted considerable attention. Due to the essential role of the cellular heat sho...
The Hong Kong oyster Magallana hongkongensis, previously known as Crassostrea hongkongensis, is a true oyster species native to the estuarine-coast of the Pearl River Delta in southern China. The species—with scientific, ecological, cultural, a...
Triflumizole (TFZ) toxicity must be investigated in the aquatic environment to understand the potential risks to aquatic species. Accordingly, the adverse effects of TFZ exposure in zebrafish were investigated. Results demonstrate that, after TFZ exp...
Aims: We hypothesized that critically ill patients with SARS-CoV-2 infection and insulin resistance would present a reduced Heat Shock Response (HSR), which is a pathway involved in proteostasis and anti-inflammation, subsequently leading to worse ou...
Tungsten powder/polytetrafluoroethylene (W/PTFE) composites have the potential to replace traditional metallic materials as casings for controllable power warheads. Under explosive loading, they generate high-density and relatively uniformly distribu...
Ring-stiffened cylindrical shells are widely used as load-bearing components in submarine pressure-hull sections. Existing underwater explosion studies have mainly emphasized incident-face denting or global failure, leaving unresolved how circumferen...
The heat shock protein 70 (Hsp70) family mediates responses to environmental stress in insects. The wheat midge Sitodiplosis mosellana, a worldwide pest, avoids summer and winter temperature extremes by diapause of the third-instar larvae in the soil...
Food production shocks can lead to food crises where access to appropriate quantities and quality of food become inadequate, unaffordable, or unreliable on a major scale. While the physical causes of food production shocks are well researched, the dy...
The high-frequency and high-amplitude pyroshock environment during the use of spacecraft will cause damage to the equipment. To simulate this environment, a pyroshock environment simulator based on electromagnetic excitation is presented in this work...
Shock attenuation is a significant aspect of shockproof design. The aim of this study is to explore the use of lattice structures for shock isolation applications. Five lattice structures were fabricated using photopolymer resin and subjected to quas...
In response to temperature downshift, a number of changes occur in cellular physiology such as, (i) decrease in membrane fluidity, (ii) stabilization of secondary structures of nucleic acids leading to reduced efficiency of mRNA translation and tran...
This paper uses a quantile impulse response approach to investigate the impact of oil price shocks on Chinese stock returns. This process allows us to uncover asymmetric effects of oil price shocks on stock market returns by taking into account the d...
The 70 kDa heat shock proteins play important roles in protecting organisms against environmental stresses, which are divided into stress-inducible forms (HSP70s) and heat shock cognates (HSC70s). In this study, heat shock protein 70 family was ident...
Low temperature is among the important factors affecting the distribution, survival, growth, and physiology of aquatic animals. In this study, coordinated transcriptomic responses to 10 °C acute cold stress were investigated in the gills, hearts,...
Crude oil price shocks have led to a fluctuation in commodity prices through the industrial chain and supply–demand relationships, which can substantially influence a country’s economy. In this paper, we propose a transmission model of oi...
The output of a single-degree-of-freedom (SDOF) piecewise linear system with asymmetric damping and linear stiffness excited by Dirac impulse excitation is studied. Analytical solutions of the response for piecewise linear systems are obtained by rep...
In this paper, dynamic response of composite cylindrical shells subjected to shock loading is studied analytically. The equations of motion are based on Sanders theory of thin shell. The effects of transverse shear deformation and rotatory inertia ar...
Plants are capable of responding to various environmental stresses by initiating the expression of genes that encode proteins involved in plant growth, fruit ripening, maintaining protein homeostasis, and combating heat stress (HS) by activating heat...
The Earth’s magnetospheric cusp, a region with an off-equatorial magnetic field minimum, is an important place which directly transports plasma and energy from the solar wind into the magnetosphere and ionosphere. Its magnetic topology and char...
Honey bees (Apis mellifera) are an agriculturally important pollinator species that live in easily managed social groups (i.e., colonies). Unfortunately, annual losses of honey bee colonies in many parts of the world have reached unsustainable levels...
Compared to other animal species, production has dramatically increased in the poultry sector. However, in intensive production systems, poultry are subjected to stress conditions that may compromise their well-being. Much like other living organisms...
(1) Background: Amyotrophic lateral sclerosis (ALS) is a multifactorial non-cell autonomous disease where activation of microglia and astrocytes largely contributes to motor neurons death. Heat shock proteins have been demonstrated to promote neurona...
Climate change and the increasing frequency of high temperature (HT) events are significant threats to global crop yields. To address this, a comprehensive understanding of how plants respond to heat shock (HS) is essential. Signaling pathways involv...
Mediterranean climates, characterised by hot and dry summers, have predictable fire regimes, and many species with physical seed dormancy (PY) thrive after wildfires. While it is well known that PY is released after heat shock in these species, intra...
Compression–torsion lattice structures (CTLS) exhibit coupled compressive–torsional deformation, yet their response under underwater shock loading remains to be further investigated. In this study, sandwich structures with CTLS cores were...
Morels (Morchella spp.), as one of the rare macroascomycetes that can be cultivated artificially, possess significant economic and scientific values. Morel cultivation is highly sensitive to elevated temperatures; however, the mechanisms of their res...
This study examines the dynamic response of bottom-sitting steel shell structures subjected to underwater shock waves. A computational framework integrating the Arbitrary Lagrangian Eulerian (ALE) method was implemented in finite-element analysis to...
Early-stage dynamic responses of naval structures under underwater explosion shock loads exhibit high-frequency, intense amplitude fluctuations and short durations, serving as critical factors for the development of plastic deformation and other dama...
This paper examines the relationship between a technology shock and employment, considering price, wage rigidities, and heterogeneous agents. To explore this relationship, we utilized a Dynamic Stochastic General Equilibrium (DSGE) model, incorporati...
Background: Non-alcoholic fatty liver disease (NAFLD) is linked with metabolic syndrome. Previous studies showed that obesity may disrupt adrenal function and adversely affect its counter-regulations against shock. This study hence evaluated adrenal...
Severe or major burns induce a pathophysiological, immune, and inflammatory response that can persist for a long time and affect morbidity and mortality. Severe burns are followed by a “hypermetabolic response”, an inflammatory process that can be ex...
Septic shock is the most severe complication of sepsis, being characterized by a systemic inflammatory response following bacterial infection, leading to multiple organ failure and dramatically high mortality. Aquaporin-9 (AQP9), a membrane channel p...
Entamoeba histolytica (E. histolytica) exhibits a remarkable capacity to respond to thermal shock stress through a sophisticated genetic regulation mechanism. This process is carried out via Heat Shock Response Elements (HSEs), which are recognized b...
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