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250 Results Found

  • Article
  • Open Access
4 Citations
2,894 Views
16 Pages

In this paper, micromechanical constitutive models are developed to predict the tensile and fatigue behavior of fiber-reinforced ceramic-matrix composites (CMCs) considering matrix fragmentation and closure. Damage models of matrix fragmentation, int...

  • Article
  • Open Access
642 Views
21 Pages

11 September 2025

A randomly generated fuzzy matrix refers to a fuzzy matrix in which the values of elements belong to the sample space of a [0,1]-random variable that follows a certain probability distribution. This paper studies the max–min transitive closure...

  • Article
  • Open Access
434 Views
11 Pages

Bioresorbable Polylactic Acid Matrix for Chronic Non-Healing Wounds: First Clinical Experience in Europe

  • Ioannis-Fivos Megas,
  • Paul Christian Fuchs,
  • Florian Pinterits,
  • Akshay Mrigendra Jain,
  • Panagiotis Fikatas,
  • Götz Habild,
  • Sarina Delavari and
  • David Breidung

31 December 2025

Background/Objectives: Bioresorbable polylactic acid (PLA) matrices have shown promise in supporting wound healing through their biocompatibility, tissue integration, and potential involvement in immune regulatory mechanisms. This study aimed to anal...

  • Article
  • Open Access
1,017 Views
22 Pages

20 July 2025

During the construction of large-span steel truss arch bridges, challenges such as complex control calculations, frequent adjustments of the cantilever structure, and deviations in the closure state often arise in the process of the assembly and clos...

  • Article
  • Open Access
1 Citations
1,814 Views
25 Pages

Adaptive Feature Refinement and Weighted Similarity for Deep Loop Closure Detection in Appearance Variation

  • Zhuolin Peng,
  • Rujun Song,
  • Hang Yang,
  • Ying Li,
  • Jiazhen Lin,
  • Zhuoling Xiao and
  • Bo Yan

18 July 2024

Loop closure detection (LCD), also known as place recognition, is a crucial component of visual simultaneous localization and mapping (vSLAM) systems, aiding in the reduction of cumulative localization errors on a global scale. However, changes in en...

  • Review
  • Open Access
16 Citations
8,314 Views
29 Pages

Shape Memory Alloy Reinforced Self-Healing Metal Matrix Composites

  • Masum Bellah,
  • Michael Nosonovsky and
  • Pradeep Rohatgi

6 June 2023

This paper reviews the synthesis, characterization, healing assessment, and mechanics of NiTi and other shape memory alloy (SMA)-reinforced self-healing metal matrix composites (SHMMCs). Challenges to synthesizing and characterizing the SMA-reinforce...

  • Case Report
  • Open Access
2 Citations
2,566 Views
8 Pages

The enucleation procedure is a standard treatment for jaw cysts; however, it often results in post-operative bony defects. These defects can lead to serious complications such as the risk of pathologic fracture and delayed wound healing, especially i...

  • Article
  • Open Access
3 Citations
5,125 Views
13 Pages

Investigation of Tactile Illusion Based on Gestalt Theory

  • Hiraku Komura,
  • Toshiki Nakamura and
  • Masahiro Ohka

Time-evolving tactile sensations are important in communication between animals as well as humans. In recent years, this research area has been defined as “tactileology,” and various studies have been conducted. This study utilized the tactile Gestal...

  • Review
  • Open Access
44 Citations
11,764 Views
14 Pages

The ductus arteriosus (DA) connects the main pulmonary artery and the aorta in fetal circulation and closes spontaneously within days after birth in normal infants. Abnormal patent DA (PDA) causes morbidities and mortality, especially in preterm infa...

  • Article
  • Open Access
3 Citations
1,323 Views
13 Pages

26 September 2025

Background/Objectives: Treatment of hard-to-heal wounds remains a challenge in clinical practice. This study aimed to assess the real-world efficacy of a novel porcine placental extracellular matrix (PPECM; InnovaMatrix® AC, Convatec, Memphis, TN...

  • Article
  • Open Access
8 Citations
7,302 Views
35 Pages

6 November 2021

Tailings dams remain on site following mine closures and must be designed and reclaimed to meet long-term goals, which may include walk-away closure or long-term care and maintenance. The underperformance of these structures can result in significant...

  • Article
  • Open Access
2 Citations
2,660 Views
19 Pages

4 September 2025

Floyd–Warshall’s algorithm is a widely-known procedure for computing all-pairs shortest paths in a graph of n vertices in Θ(n3) time complexity. A simplified version of the same algorithm computes the transitive closure of the graph...

  • Review
  • Open Access
10 Citations
7,493 Views
17 Pages

The ductus arteriosus (DA) is a shunt vessel between the aorta and the pulmonary artery during the fetal period that is essential for the normal development of the fetus. Complete closure usually occurs after birth but the vessel might remain open in...

  • Article
  • Open Access
6 Citations
2,923 Views
18 Pages

24 May 2022

This paper presents a robust method based on graph topology to find the topologically correct and consistent subset of inter-robot relative pose measurements for multi-robot map fusion. However, the absence of good prior on relative pose gives a seve...

  • Communication
  • Open Access
30 Citations
6,691 Views
16 Pages

Co-Graft of Acellular Dermal Matrix and Split Thickness Skin Graft—A New Reconstructive Surgical Method in the Treatment of Hidradenitis Suppurativa

  • Marcin Gierek,
  • Wojciech Łabuś,
  • Anna Słaboń,
  • Karolina Ziółkowska,
  • Gabriela Ochała-Gierek,
  • Diana Kitala,
  • Karol Szyluk and
  • Paweł Niemiec

Hidradenitis suppurativa is a chronic disease that significantly reduces patients’ quality of life. Patients are chronically treated with systemic therapies, which are often ineffective. Surgical treatment for severe cases of hidradenitis suppu...

  • Article
  • Open Access
7 Citations
3,140 Views
13 Pages

Curcumin-Loaded Nanofibrous Matrix Accelerates Fibroblast Cell Proliferation and Enhances Wound Healing via GSK3-β Inhibition

  • Kiran Konain,
  • Nayyer Saddique,
  • Muhammad Samie,
  • Zia Ur Rahman,
  • Sajida Farid,
  • Shazia Hameed,
  • Munazza R. Mirza,
  • Wenhui Wu,
  • Kyung Mi Woo and
  • Saeed Ur Rahman
  • + 1 author

21 August 2023

Wound healing is a multifaceted biological process influenced by both intrinsic and extrinsic factors. The ability of Wnt signaling to activate cell proliferation appears to serve a central role in wound healing. Therefore, the direct activation of W...

  • Article
  • Open Access
11 Citations
3,973 Views
17 Pages

Multi-View Laser Point Cloud Global Registration for a Single Object

  • Shuai Wang,
  • Hua-Yan Sun,
  • Hui-Chao Guo,
  • Lin Du and
  • Tian-Jian Liu

1 November 2018

Global registration is an important step in the three-dimensional reconstruction of multi-view laser point clouds for moving objects, but the severe noise, density variation, and overlap ratio between multi-view laser point clouds present significant...

  • Article
  • Open Access
1 Citations
2,296 Views
20 Pages

Multispectral Pulsed Photobiomodulation Enhances Re-Epithelialization via Keratinocyte Activation in Full-Thickness Skin Wounds

  • Joo Hyun Kim,
  • Delgerzul Baatar,
  • Myung Jin Ban,
  • Ji Won Son,
  • Jihye Choi,
  • Chan Hee Gil,
  • Min-Kyu Kim,
  • Sung Sik Hur,
  • Jung Eun Kim and
  • Yongsung Hwang

10 September 2025

Chronic wound healing is a complex and tightly regulated process requiring coordinated epithelial and stromal regeneration. Photobiomodulation (PBM) using low-level red light-emitting diode (LED) therapy has emerged as a non-invasive approach to enha...

  • Article
  • Open Access
3 Citations
2,756 Views
12 Pages

1 April 2025

(1) Background: Achieving a complete and secure dural closure to prevent cerebrospinal fluid (CSF) leakage is a critical concern in microvascular decompression (MVD). Proper dural closure minimizes complications, such as infections caused by CSF leak...

  • Review
  • Open Access
23 Citations
9,699 Views
21 Pages

The healing of deep skin wounds is a complex phenomenon evolving according with a fine spatiotemporal regulation of different biological events (hemostasis, inflammation, proliferation, remodeling). Due to the spontaneous evolution of damaged human d...

  • Article
  • Open Access
7 Citations
3,694 Views
10 Pages

Use of Plasma Rich in Growth Factors and ReGeneraTing Agent Matrix for the Treatment of Corneal Diseases

  • Ronald M. Sánchez-Ávila,
  • Edmar Uribe-Badillo,
  • Carlos Fernández-Vega González,
  • Francisco Muruzabal,
  • Borja de la Sen-Corcuera,
  • Begoña Baamonde,
  • Luis M. Quirós,
  • Eduardo Anitua and
  • Jesús Merayo-Lloves

2 July 2021

This study aimed to investigate the use of Plasma Rich in Growth Factors (PRGF) associated with tissue ReGeneraTing Agent (RGTA) drops for the treatment of noninfectious corneal ulcers. RGTA treatment was applied (one drop every two days); however, i...

  • Review
  • Open Access
709 Citations
35,069 Views
10 Pages

Macrophage Phenotypes Regulate Scar Formation and Chronic Wound Healing

  • Mark Hesketh,
  • Katherine B. Sahin,
  • Zoe E. West and
  • Rachael Z. Murray

Macrophages and inflammation play a beneficial role during wound repair with macrophages regulating a wide range of processes, such as removal of dead cells, debris and pathogens, through to extracellular matrix deposition re-vascularisation and woun...

  • Article
  • Open Access
3,582 Views
24 Pages

9 October 2024

In visual Simultaneous Localization and Mapping (SLAM), operational efficiency and localization accuracy are equally crucial evaluation metrics. We propose an enhanced visual SLAM method to ensure stable localization accuracy while improving system e...

  • Article
  • Open Access
4 Citations
7,142 Views
19 Pages

19 April 2024

Background: Wound healing in deep dermal burn injuries continues to be a challenge in paediatrics. In the absence quick and spontaneous wound closure, split-thickness skin grafting is often necessary. Since the development of a new type of acellular...

  • Article
  • Open Access
376 Views
19 Pages

8 March 2026

Acute and chronic wounds are a major clinical burden, with persistent inflammation, impaired fibroblast function, defective angiogenesis, and disordered extracellular matrix deposition. The translational potential of existing in vitro models is limit...

  • Article
  • Open Access
18 Citations
5,107 Views
20 Pages

27 March 2019

Multi-stage hydraulic fracturing along with horizontal wells are widely used to create complex fracture networks in tight oil reservoirs. Analysis of field flowback data shows that most of the fracturing fluids are contained in a complex fracture net...

  • Article
  • Open Access
8 Citations
2,415 Views
24 Pages

The existence of fracture flow has an undesirable effect on the creation of the frozen wall. Brine and liquid nitrogen combined freezing technology can ensure the safety of freezing engineering, reduce the construction period and save cost. Consideri...

  • Article
  • Open Access
397 Views
11 Pages

Fibroblast Growth Factor-2 and Enamel Matrix Derivative Enhance Proliferation, Migration, and Wound Healing in Gingival Epithelial and Fibroblast Cells

  • Nanako Tsuchimochi,
  • Naoki Maruo,
  • Kimiko Ohgi,
  • Hiroaki Yamato,
  • Masanobu Nakagami,
  • Aya Fujioka and
  • Yasunori Yoshinaga

23 January 2026

Background and Objectives: Soft-tissue healing, particularly rapid epithelialization, is a critical determinant of successful periodontal regenerative therapy. Fibroblast growth factor-2 (FGF-2) and enamel matrix derivative (EMD) are regenerative bio...

  • Article
  • Open Access
4 Citations
2,069 Views
14 Pages

Utilization of a Multi-Tissue Extracellular Matrix in Complex Wound Care in Gaza: A Case Series

  • Bilal Irfan,
  • Adam Hamawy,
  • Ruba Musallam,
  • Rahaf Abudagga,
  • Sameer Khan,
  • Nour Alshaer,
  • Mohammed Tabash,
  • Abdullah Ghali,
  • Khaled Saleh and
  • Mohammed Tahir

2 September 2025

Purpose: This case series examines the feasibility and outcomes of using a multi-tissue extracellular matrix (ECM) powder as an adjunct to standard wound care in a conflict zone. Primary objectives were granulation by day 7, wound closure, and minimi...

  • Article
  • Open Access
56 Citations
5,782 Views
13 Pages

Defect of Interferon γ Leads to Impaired Wound Healing through Prolonged Neutrophilic Inflammatory Response and Enhanced MMP-2 Activation

  • Emi Kanno,
  • Hiromasa Tanno,
  • Airi Masaki,
  • Ayako Sasaki,
  • Noriko Sato,
  • Maiko Goto,
  • Mayu Shisai,
  • Kenji Yamaguchi,
  • Naoyuki Takagi and
  • Kazuyoshi Kawakami
  • + 11 authors

12 November 2019

Interferon (IFN)-γ is mainly secreted by CD4+ T helper 1 (Th1), natural killer (NK) and NKT cells after skin injury. Although IFN-γ is well known regarding its inhibitory effects on collagen synthesis by fibroblasts in vitro, information...

  • Article
  • Open Access
5 Citations
2,557 Views
16 Pages

Arsenic Impairs Wound Healing Processes in Dermal Fibroblasts and Mice

  • Sara R. Dresler,
  • Bronson I. Pinto,
  • Matthew C. Salanga,
  • Catherine R. Propper,
  • Savannah R. Berry and
  • Robert S. Kellar

10 February 2024

Inorganic arsenic (NaAsO2) is a naturally occurring metalloid found in water resources globally and in the United States at concentrations exceeding the U.S. Environmental Protection Agency Maximum Contamination Level of 10 ppb. While exposure to ars...

  • Article
  • Open Access
13 Citations
1,597 Views
19 Pages

The application of high-pressure fluid induces the closure of isolated pores inside the matrix and promotes the generation of new fractures, resulting in a compressive effect on the matrix. To examine the compressibility of coal-measure shale samples...

  • Article
  • Open Access
17 Citations
4,358 Views
16 Pages

1 April 2022

Hydrogels are widely used in tissue engineering as materials that regulate cell proliferation, migration, and differentiation. They also act as promising biomaterials that can provide a variety of stimuli by influencing the surrounding microenvironme...

  • Article
  • Open Access
4 Citations
2,282 Views
15 Pages

3 October 2023

Neutrinoless double beta decay is a pivotal weak nuclear process that holds the potential to unveil the Majorana nature of neutrinos and predict their absolute masses. In this study, we delve into examining the impact of spin-dependent short-range co...

  • Article
  • Open Access
15 Citations
3,814 Views
21 Pages

Aerosols in Northern Morocco-2: Chemical Characterization and PMF Source Apportionment of Ambient PM2.5

  • Abdelfettah Benchrif,
  • Mounia Tahri,
  • Benjamin Guinot,
  • El Mahjoub Chakir,
  • Fatiha Zahry,
  • Bouamar Bagdhad,
  • Moussa Bounakhla,
  • Hélène Cachier and
  • Francesca Costabile

17 October 2022

Insufficient data on the chemical composition of PM2.5 and its emission sources in the southwestern (SW) Mediterranean area has been identified. Ambient PM2.5 samples were collected in an urban area of Tetouan city, northern Morocco. Chemical mass cl...

  • Article
  • Open Access
27 Citations
2,554 Views
19 Pages

Nuclear Matrix Elements for Heavy Ion Sequential Double Charge Exchange Reactions

  • Horst Lenske,
  • Jessica Bellone,
  • Maria Colonna and
  • Danilo Gambacurta

The theoretical approach to a sequential heavy ion double charge exchange reaction is presented. A brief introduction into the formal theory of second-order nuclear reactions and their application to Double Single Charge Exchange (DSCE) reactions by...

  • Article
  • Open Access
12 Citations
3,195 Views
33 Pages

Cutting Process Consideration in Dynamic Models of Machine Tool Spindle Units

  • Yurii Danylchenko,
  • Michael Storchak,
  • Mariia Danylchenko and
  • Andrii Petryshyn

Reducing the deviation effect from the specified machining conditions on the quality of the process in real time is the desired result of the intelligent spindle control system. To implement such a control system, a dynamic interaction model of the t...

  • Article
  • Open Access
136 Views
22 Pages

Effective management of acute, complex, and chronic wounds requires constructs that simultaneously support tissue repair and provide sustained infection control. Biologic-derived materials, despite their regenerative potential, are limited by insuffi...

  • Article
  • Open Access
407 Views
16 Pages

Lie Saturate and Controllability

  • Victor Ayala,
  • Bruno A. Rodrigues,
  • Alexandre J. Santana and
  • Maria Luisa Torreblanca Todco

21 November 2025

We study the controllability of right-invariant bilinear systems on the complex and quaternionic special linear groups Sl(n,C) and Sl(n,H). The analysis relies on the Lie saturateLS(Γ), which characterizes controllability through convexity and...

  • Article
  • Open Access
387 Views
23 Pages

Local ADSC Delivery Methods Accelerate Healing of Large Unburned Full-Thickness Skin Defects by Promoting an Optimal Wound Microenvironment

  • Semra Gürünlüoğlu,
  • Basri Satılmış,
  • Mehmet Gül,
  • Muhammed Dündar,
  • Kubilay Gürünlüoğlu,
  • Ezgi Karaaslan,
  • Ahmet Koç,
  • Mehmet Aslan,
  • Sezai Yılmaz and
  • Tevfik Tolga Şahin
  • + 1 author

18 February 2026

Background: This study introduces an experimental model of a large, full-thickness skin defect and evaluates how adipose-derived stem cells characterized by high self-renewal and differentiation capacity affect both wound healing and the wound microe...

  • Article
  • Open Access
21 Citations
3,674 Views
23 Pages

The Effect of Exposure on the Autogenous Self-Healing of Ordinary Portland Cement Mortars

  • Magdalena Rajczakowska,
  • Karin Habermehl-Cwirzen,
  • Hans Hedlund and
  • Andrzej Cwirzen

27 November 2019

Exposure conditions are critical for the autogenous self-healing process of Portland cement based binder matrixes. However, there is still a significant lack of fundamental knowledge related to this factor. The aim of this paper was to investigate an...

  • Article
  • Open Access
1 Citations
789 Views
14 Pages

Comparison Between Titanium and Thermally Activated Prostheses in Stapes Surgery

  • Mila Vasiljević,
  • Klara Dragović,
  • Petra Povalej Bržan and
  • Janez Rebol

23 July 2025

This study investigates hearing outcomes of stapedotomy using two different types of prostheses: manually crimped MatriX and thermally activated NiTiBOND. The primary objective was to determine whether the method of prosthesis fixation to the long pr...

  • Review
  • Open Access
8 Citations
5,563 Views
16 Pages

The Multiple Faces of Integrin–ECM Interactions in Inflammatory Bowel Disease

  • Valentina Garlatti,
  • Sara Lovisa,
  • Silvio Danese and
  • Stefania Vetrano

28 September 2021

Inflammatory Bowel Disease (IBD) comprises a series of chronic and relapsing intestinal diseases, with Crohn’s disease and ulcerative colitis being the most common. The abundant and uncontrolled deposition of extracellular matrix, namely fibrosis, is...

  • Article
  • Open Access
393 Views
8 Pages

Reconstruction of Surgical Defects of the Oral Cavity with Bilayer Dermal Matrix: Our Experience

  • Andrea Ferri,
  • Mara David,
  • Giulia Salti,
  • Giovanni Lilloni,
  • Bernardo Bianchi and
  • Silvano Ferrari

1 December 2025

Purpose: Reconstructive options for mucosal defects of the oral cavity resulting from the resection of tumors include primary closure, mucosal and split thickness skin grafts, pedicle flaps, and microvascular free flaps. Lately the use of an acellula...

  • Article
  • Open Access
4 Citations
2,905 Views
21 Pages

Inadequate wound healing of ocular surface injuries can lead to permanent visual impairment. The relaxin ligand-receptor system has been demonstrated to promote corneal wound healing through increased cell migration and modulation of extracellular ma...

  • Article
  • Open Access
10 Citations
5,103 Views
13 Pages

Anti-Fibrotic Effects of RF Electric Currents

  • María Luisa Hernández-Bule,
  • Elena Toledano-Macías,
  • Luis Alfonso Pérez-González,
  • María Antonia Martínez-Pascual and
  • Montserrat Fernández-Guarino

Hypertrophic scars and keloids are two different manifestations of excessive dermal fibrosis and are caused by an alteration in the normal wound-healing process. Treatment with radiofrequency (RF)-based therapies has proven to be useful in reducing h...

  • Feature Paper
  • Article
  • Open Access
20 Citations
3,671 Views
10 Pages

8 November 2019

TiB-reinforced Ti-3Al-2.5V matrix composites, in which TiB whiskers are oriented parallel to the direction of heat extrusion, were fabricated via mechanical alloying and hot isostatic pressing (HIP). To investigate the near-threshold fatigue crack pr...

  • Article
  • Open Access
552 Views
16 Pages

Experimental Study on Stress Sensitivity in Fractured Tight Conglomerate Reservoirs

  • Bin Wang,
  • Wanli Xing,
  • Xue Meng,
  • Kaixin Liu,
  • Weijie Zheng and
  • Binfei Li

27 October 2025

Tight conglomerate reservoirs are characterized by dense lithology, significant compositional contrasts between cement and gravel, strong stress gravel content, strong heterogeneity, and uneven spatial distribution, which collectively result in low p...

  • Case Report
  • Open Access
1 Citations
2,363 Views
12 Pages

Multidisciplinary Management of Non-Healing Umbilical Ulcer in an Infant: A Case Report

  • Stefano L’Erario,
  • Marena Francesco,
  • Franco Bassetto and
  • Antonio Amabile

This case report outlines the intricate clinical management of a 5-month-old infant with recurrent bacterial infections and a non-healing umbilical ulcer following the surgical excision of a urachal remnant. The infant’s medical history was sig...

  • Article
  • Open Access
1,051 Views
12 Pages

Intraoperative Management of Lateral Semicircular Canal Fistula in Cholesteatoma Surgery: Retrospective Case Series and Audiovestibular Follow-Up

  • Maria Denisa Zica,
  • Catalina Voiosu,
  • Andreea Rusescu,
  • Irina Ionita,
  • Luana Maria Gherasie,
  • Oana Ruxandra Alius,
  • Alexandra Bizdu Branovici,
  • Razvan Hainarosie and
  • Viorel Zainea

30 November 2025

Background and Objectives: To evaluate the surgical management and outcomes of lateral semicircular canal fistulas (LSCFs) in patients with middle ear cholesteatoma, focusing on hearing preservation and vestibular function. Materials and Methods: A r...

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