Background: Electrodiagnostic (EDx) studies are crucial for diagnosing neuromuscular diseases and are considered a complement to neurological examinations. Their effectiveness is highly dependent on the quality of the initial clinical diagnosis, medi...
The Japanese label specifies suvorexant 20 mg once nightly for adults and 15 mg once nightly for older adults, but dose selection has not been characterized across all doses. We conducted a single-center retrospective drug-utilization study of outpat...
Script Concordance Tests (SCTs) assess clinical reasoning under uncertainty. While construction guidelines exist, the feasibility of collaborative development approaches and educators’ real-time experiences remain underreported. This feasibilit...
Background/Objectives: AnemiaScore is an investigator-developed, deterministic, rule-based clinical decision-support framework for cancer-related anemia. This initial proof-of-concept study evaluated agreement with recorded local oncologist decisions...
Background: The optimal number of electrodiagnostic tests required to confirm carpal tunnel syndrome (CTS) has not been systematically evaluated. While single comparative latency study (COLS) is commonly used, it remains unclear whether diagnostic ac...
Background: The primary aim of our study was to assess the correlation between an improved version of the attenuation coefficient available on the Arietta 850 ultrasound system (iATT, Fujifilm Healthcare, Tokyo, Japan) and controlled attenuation para...
Introduction: It is currently considered that screening for frailty in elderly subjects is a major public health issue. Methods: a cross-sectional pilot study involving elderly subjects (over 75 years of age) admitted at the emergency department of t...
Obesity is a major public health problem in Peru. Cohabiting couples may show obesity clustering because of partner selection, shared household routines, and broader structural exposures. This study aimed to describe spousal similarity in body mass i...
This study aims to investigate spousal concordance in dietary behaviors, spousal concordance in metabolic components (MCs), and their association. A cross-sectional survey was conducted in Taiwan from November 2014 to May 2015. Matched-pair analysis,...
The high frequency and complexity of mandibular third molar (M3M) surgery have led several authors to the development of classification systems for better evaluation and management in oral surgery. This study compared the classifications of Juodzabal...
Background: Clinical pathways are associated with improved adherence to clinical guidelines; however, most studies have evaluated pathways for a single intervention at a single institution. The objective of the present study was to develop and evalua...
Guidelines recommend initiation of statins depending on cardiovascular risk and low-density lipoprotein cholesterol (LDL-C) levels. In this retrospective cohort study, we aimed to assess guideline concordance of statin treatment decisions and to find...
23 January 2022
Introduction: Health authorities use different systems of influenza surveillance. Sentinel networks, which are recommended by the World Health Organization, provide information on weekly influenza incidence in a monitored population, based on laborat...
6 March 2023
During a pandemic, and given the need to quickly screen febrile and non-febrile humans, it is necessary to know the concordance between different thermometers (TMs) and understand how environmental factors influence the measurements made by these ins...
Background/Objectives: To evaluate the concordance of three general-purpose large language models (LLMs), ChatGPT, Claude, and Gemini, with an adjudicated expert consensus classification of Stage, Grade, and Extent in Stage III–IV periodontitis...
Background: The molecular concordance between primary lung adenocarcinoma and metastatic lesions remains incompletely characterized despite its direct implications for precision oncology and biopsy-driven therapeutic decision-making. This prospective...
The article presents research on the possibilities of utilising the Lean Management method to increase the profitability of coal mining operations through cost rationalisation and production optimisation. The Lean Management method has its roots in t...
Background: Structured patient education (SPE) is a critical component of diabetes management, with the potential to reduce its physical, social, and economic burden. National and international guidelines emphasise the importance of raising awareness...
Background: Health education is a vital component of preventative care; however, rural Filipino adults often face structural, linguistic, and access barriers to obtaining reliable health information. Designing equitable and culturally relevant health...
Background/Objective: In recent years, artificial intelligence (AI) has gained increasing prominence in the fields of diagnostic decision-making in medicine. The aim of this study was to compare multidisciplinary team (MDT: rheumatology, pulmonology,...
Preimplantation genetic testing for aneuploidy (PGT-A) is widely used to select euploid embryos for in vitro fertilization (IVF), but its accuracy in predicting the implantation potential for full segmental aneuploid (Seg-A) embryos remains unclear....
High-grade serous ovarian carcinoma (HGSOC) is characterized by profound genomic instability and spatial heterogeneity. Liquid biopsy, utilizing circulating tumor DNA (ctDNA), offers a non-invasive approach to capture the comprehensive mutational lan...
The professional association has already developed guidelines on the appropriate use of handheld ultrasound devices, especially in an emergency setting. Handheld ultrasound devices are seen as the ‘stethoscope of the future’ to assist in...
Immunohistochemistry (IHC) and polymerase chain reaction (PCR) and fragment separation by capillary electrophoresis represent the current clinical laboratory standard for the evaluation of microsatellite instability (MSI) status. The importance of re...
Background/Objectives: Parent–child dietary resemblance is well documented, but concordance in Mediterranean Diet adherence and fast-food consumption within the same family dyads remains underexplored in Portugal. This exploratory study examine...
The research aims to verify the concordance between the skeletal maturity index (SMI) measured on the hand and wrist X-rays using Fishman method and the cervical vertebral maturation stage (CVMS), measured on the lateral cephalometric X-rays using Ba...
4 October 2022
Epidemiological studies have suggested the role of multiple genetic and environmental factors in the development of non-neoplastic gastrointestinal (GI) diseases; however, little information is available on these factors in the Korean population. The...
Background and Objectives: Large language models, a form of artificial intelligence (AI), can answer common patient questions about total hip arthroplasty (THA), but most evaluations emphasize clinician-rated accuracy or patient preference rather tha...
Before Chuna manual therapy (CMT), a manual therapy applied in Korean medicine, CMT spinal diagnosis using palpation or X-ray is performed. However, studies on the inter-rater concordance of CMT diagnostic methods, concordance among diagnostic method...
Carbapenem-resistant Acinetobacter baumannii (CRAB) bacteremia is a critical health concern associated with high morbidity and mortality and limited treatment options. Whether early initiation of concordant antibiotic therapy upon recognition of seps...
4 March 2022
This study analyzes the degree of agreement between three self-report measures (Walking Behavior, WALK questionnaire and logbooks) assessing adherence to walking programs through reporting their components (minutes, rests, times a week, consecutive w...
Fat-soluble vitamers (FSV) are a class of diverse organic substances important in a wide range of biological processes, including immune function, vision, bone health, and coagulation. Profiling FSV in parents and children enables insights into gene-...
Several epidemiological studies have demonstrated that genetic and environmental factors contribute to the development of allergic diseases. However, there is limited information on these factors in the Korean population. This study investigated the...
Introduction: Acute otitis media (AOM) is a common pediatric condition requiring careful assessment to distinguish children needing medical referral from those suitable for watchful waiting. Community pharmacists are often the first healthcare profes...
Determination of language hemispheric dominance (HD) in patients undergoing evaluation for epilepsy surgery has traditionally relied on the sodium amobarbital (Wada) test. The emergence of non-invasive methods for determining language laterality has...
While diet and lifestyle are independently implicated in the etiology of liver disease, the interaction of diet and lifestyle may be more helpful for determining the risk of liver abnormality. Thus, our study aimed to evaluate the interaction between...
Background/Objectives: This GLP (Good laboratory practice) study evaluates the MRI compatibility and occlusion performance of the Nuvascular Harbor intrasaccular device for the treatment of bifurcation and sidewall aneurysms in a rabbit aneurysm mode...
Insufficient space below the Deep Transverse Metatarsal Ligament (DTML) could be an etiological factor for Morton’s Neuroma (MN). To date, there is a lack of studies measuring the space below the DTML. For this reason, this study assesses the intra-...
28 August 2021
Desquamative gingivitis (DG) denotes a heterogeneous immune-mediated disease for which early diagnosis represents a great challenge. The main aim of this study is to validate diagnostic concordance between specific Optical Coherence Tomography (OTC)...
This study investigated the contribution of genetic and environmental factors to cardiometabolic diseases (CMDs) by comparing disease concordance in monozygotic and dizygotic twins. This cross-sectional study analyzed 1294 (1040 monozygotic and 254 d...
Introduction: We designed a new scale for the rapid detection of frailty for use in primary care, referred to as the Zulfiqar Frailty Scale (ZFS). Objective: To evaluate the performance of the “ZFS” tool to screen for frailty as defined i...
Background: Accurate endotracheal tube (ETT) insertion depth is critical in infants and young children, where tracheal malposition carries significant risk. Formula-based depth estimation is widely used at the bedside, but the performance of publishe...
Background/Objectives: In many low- and middle-income countries (LMICs), including Bosnia and Herzegovina, oncology services are constrained by a limited number of specialists and uneven access to evidence-based care. Artificial intelligence (AI), pa...
Background/Objectives: Comparative evidence for GPR system selection in forensic search is scarce. This exploratory study assesses the short-term repeatability and inter-system concordance of two GPR acquisition–interpretation chains: the multi...
Background/Objectives: Septic shock carries high mortality. Although guidelines recommend early empiric antibiotics, early identification of the infection source and selection of appropriate initial antibiotic therapy remain challenging. This study e...
The immunohistochemical (IHC) or fluorescence/chromogenic in situ hybridization (FISH/CISH) assays for assessing HER2 are now recommended by the American Society of Clinical Oncologists and the College of American Pathologists, but there are an incre...
Background/Objectives: An intraoperative pathological assessment is essential for surgical decision-making but is limited by artifacts and a suboptimal image quality in frozen section analysis (FSA). Rapid fresh pathology (RFP), enabled by whole-moun...
Background: The reliability of large language models (LLMs) in complex oncologic decision-making remains inadequately validated. This study evaluated the concordance of ChatGPT-5 with multidisciplinary tumor board (MDT) decisions in gynecologic oncol...
Background and Objectives: Aberrant activation or overexpression of cell division cycle 42 (Cdc42) has been demonstrated in various tumors; however, its prognostic relevance in colorectal cancer (CRC) remains insufficiently defined. Thus, we evaluate...
Background: Tests or test algorithms for diagnosing HPV-driven oral cavity and laryngeal head and neck carcinomas (HNC) have not been yet validated, and the differences among oral cavity and laryngeal sites have not been comprehensively evaluated. We...
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