Background and Objectives: This study aimed to evaluate the pre- and post-treatment changes in ICEB and ICEBc score markers of cardiac electrical balance in patients presenting to the emergency department with hypertensive urgency and to investigate...
Background: The Index of Cardiac Electrophysiological Balance (ICEB) has emerged as a electrocardiographic marker reflecting the equilibrium between ventricular depolarization and repolarization. Although obesity is known to alter cardiac electrophys...
Interlocking Compressed Earth Blocks (ICEBs) offer a sustainable alternative to conventional fired-clay bricks but remain hindered by inconsistent geometric designs and limited standardization. This study develops a stakeholder-weighted Analytic Hier...
Field measurements undertaken in six paired primary school classrooms in Anambra State, Nigeria, previously demonstrated that interlocking compressed earth block (ICEB) classrooms maintained significantly lower occupied-hour temperatures than adjacen...
Background and Objective: This study aimed to investigate the relationship between tramadol use and cardio electrophysiological imbalance (iCEB/iCEBc) in general surgery patients with complaints of acute postoperative pain (APP). Materials and&n...
Background: Opioid dependence treated with buprenorphine/naloxone is associated with increased cardiovascular risk; however, data regarding aortic elasticity and cardiac electrophysiological balance during long-term maintenance therapy remain limited...
The environmental impact due to the overexploitation of nonrenewable resources, the processing and transportation of materials, and waste production is a global concern that the construction industry must urgently address, since it is among the great...
Background/Objectives: Behçet’s disease (BD) is a chronic multisystem inflammatory vasculitis associated with an increased risk of ventricular arrhythmias and sudden cardiac death. The index of cardiac electrophysiological balance (iCEB)...
21 November 2020
Background: Traumatic brain injury (TBI) is commonly associated with cardiac dysfunction, which may be reflected by abnormal electrocardiograms (ECG) and/or contractility. TBI-related cardiac disorders depend on the type of cerebral injury, the regio...
Background and Objectives: Colorectal cancer is the second leading cause of cancer-related deaths in the U.S., and colonoscopy is a critical tool for colon cancer screening and diagnosis. Electrolyte disturbances and autonomic nervous system dysfunct...
Modern life is making people infertile. Giving birth later in life is wreaking havoc on our fertility and threatening human survival. Smart cities intend to optimize the quality of life of their citizens by utilizing technology for smarter living. Th...
E-mobility is progressively penetrating the European market with the ever-increasing registration of new battery electric vehicles (BEVs). Although BEVs can significantly contribute to achieving the goal of sustainable road transport, they pose new c...
Chagas disease is a so-called “neglected disease” and endemic to Latin America. Nifurtimox and benznidazole are drugs that have considerable efficacy in the treatment of the acute phase of the disease but cause many significant side effects. Furtherm...
In view of the GHG reduction targets to be met, Brazilian researchers are looking for cleaner alternatives to energy sources. These alternatives are primarily to be applied in the transport sector, which presents high energy consumption, as well as h...
Chagas disease, also known as American trypanosomiasis, is classified as a neglected disease by the World Health Organization. For clinical treatment, only two drugs have been on the market, Benznidazole and Nifurtimox, both of which are recommended...
Chagas disease is caused by the parasite protozoan Trypanosoma cruzi (T. cruzi) and affects millions of people in over 21 countries in around the world. The main forms of treatment of this disease, benznidazole and nifurtimox, present low cure rates...
Battery electric buses (BEBs) are widely regarded as a safe and sustainable alternative to internal combustion vehicles. However, the lithium-ion batteries that power them present safety risks. This paper provides a comprehensive overview of the safe...
Arboviruses transmitted by Aedes mosquitoes, including Zika (ZIKV), Chikungunya (CHIKV), and Mayaro (MAYV) viruses, lack approved antiviral therapies. This study evaluated the cytotoxicity and antiviral activity of ethanolic extracts and fractions fr...
Furfural is a platform molecule obtained from hemicellulosic monosaccharides present in lignocellulosic biomass. Due to the possibility of converting this molecule into several value-added chemicals and the need to search for more sustainable product...
We propose a modified relativistic dynamics framework for a particle undergoing a proper acceleration a immersed in a vacuum background of temperature T. Within this framework, the Unruh effect dictates that the accelerated observer perceives the vac...
This work describes a resonance Raman study performed in the domes of monolayer MoS2 using 23 different laser excitation energies covering the visible and near-infrared (NIR) ranges. The multiple excitation results allowed us to investigate the excit...
Noncoding microRNAs are involved in lipid and carbohydrate metabolism pathways and are powerful regulators of gene expression. The goals of this study were to evaluate the temporal expression profiles of miRNAs in rat adipose tissue and predict mRNA&...
Analyzing the surface and bedrock locations in radar imagery enables the computation of ice sheet thickness, which is important for the study of ice sheets, their volume and how they may contribute to global climate change. However, the traditional h...
Malaria continues to be a major public health challenge in tropical and subtropical regions. Anopheles aquasalis, a key laboratory model for malaria research, plays a critical role in the study of vector–parasite interactions. Although vector l...
A series of novel xylitan derivatives derived from xylitol were synthesized using operationally simple procedures. A xylitan acetonide was the key intermediate used to prepare benzoate, arylsulfonate esters and 1,2,3-triazole derivatives of xylitan....
Background/Objectives: Chagas disease is a neglected tropical disease caused by infection with the parasite Trypanosoma cruzi. Benznidazole and nifurtimox are the only approved drugs for treating this condition, but their low aqueous solubility may l...
One hundred years after the flu pandemic of 1918, the world faces an outbreak of a new severe acute respiratory syndrome, caused by a novel coronavirus. With a high transmissibility, the pandemic has spread worldwide, creating a scenario of devastati...
The physician Carlos Chagas (1879–1934) described the protozoan parasite Trypanosoma cruzi and discovered a new illness named American trypanosomiases or Chagas disease (Chagas, 1909) [...]
Plant extracts are complex mixtures that are difficult to characterize, and mass spectrometry is one of the main techniques currently used in dereplication processes. Fridericia chica is a species with medicinal uses in Latin American countries, used...
Here we use karyomorphometrical analysis to characterize and evaluate the karyotype of the turtle ant Cephalotes pusillus (Klug, 1824). This is the first representative of this diverse ant genus to be cytogenetically studied. They bear a diploid chro...
The CO2 reduction by solar means has been discussed as an alternative to emission abatement, a fundamental topic for sustainable, carbon-free production in the future. However, the choice of efficient systems, starting with the catalysts, is still a...
The spin-1/2 quantum transverse Ising model, defined on a ladder structure, with nearest-neighbor and four-spin interaction on a plaquette, was studied by using exact diagonalization on finite ladders together with finite-size-scaling procedures. The...
Dengue virus, one of the most prevalent mosquito-borne flaviviruses affecting humans globally, is primarily transmitted by the Aedes aegypti mosquito, which thrives in densely populated urban environments. Dengue incidence has surged in recent decade...
2 September 2024
West Nile Virus (WNV) poses a significant global public health threat as a mosquito-borne pathogen. While laboratory mouse models have historically played a crucial role in understanding virus biology, recent research has focused on utilizing immunoc...
The therapeutic management of Chagas disease requires new medicines because the standard-of-care drugs available induce adverse effects and have limited efficacy. In this study, we developed a formulation of albaconazole (ABZ) loaded in biodegradable...
Leishmaniases are diseases caused by protozoan parasites of the genus Leishmania. Clinically, leishmaniases range from cutaneous to visceral forms, with estimated global incidences of 1.2 and 0.4 million cases per year, respectively. The treatment of...
FR235222 is a natural tetra-cyclopeptide with a strong inhibition effect on histone deacetylases, effective on mammalian cells as well as on intracellular apicomplexan parasites, such as Toxoplasma gondii, in the tachyzoite and bradyzoite stages. Thi...
15 September 2016
The prevention and control of dengue are great public health challenges for many countries, particularly since 2015, as other arboviruses have been observed to interact significantly with dengue virus. Different approaches and methodologies have been...
Immune response to biomaterials, which is intimately related to their surface properties, can produce chronic inflammation and fibrosis, leading to implant failure. This study investigated the development of magnetic nanoparticles coated with silica...
Techniques such as adsorption have been widely adopted to remove residual microplastics (MPs) because they are efficient at removing contaminants from aqueous environments. In this study, we report a novel, low-cost, biodegradable, and scalable bioco...
Cancer is one of the deadliest diseases worldwide and has been responsible for millions of deaths. However, developing a satisfactory smart multifunctional material combining different strategies to kill cancer cells poses a challenge. This work aims...
Nanomaterials based on metal oxides are extensively studied for several applications due to their versatility. Improvements in their performances can be obtained due to specific structural modifications. One possible modification is by doping the cry...
Recent studies have argued that changes in fire regimes in the 21st century are posing a major threat to global biodiversity. In this scenario, incorporating species’ physiological, ecological, and evolutionary traits with their local fire expo...