Advancements in Cardiac Imaging: Diagnostics, Prognostics, and Therapeutics

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".

Deadline for manuscript submissions: 31 May 2025 | Viewed by 588

Special Issue Editor


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Guest Editor
Interdisciplinary Department of Medicine, University of Bari “Aldo Moro”, Polyclinic University Hospital, 70124 Bari, Italy
Interests: cardiac magnetic resonance; dilated cardiomyopathy; myocardial fibrosis; parametric mapping; extracellular volume; gray zone fibrosis

Special Issue Information

Dear Colleagues,

The extensive use of non-invasive imaging methods is certainly one of the aspects that best characterize modern cardiology. These methods are currently available to determine an accurate and timely diagnosis of the main cardiovascular pathologies and to provide an important aid for choosing the best therapeutic strategy, with particular regard for new interventional procedures and new drugs available.

The implementation of percutaneous interventional procedures for the treatment of structural heart disease and the new management of chronic ischemic heart disease, metabolic storage diseases, and heart failure in clinical practice have required imaging methods to provide increasingly sophisticated evaluation parameters in order to identify patients suitable to undergo certain procedures and adopt adequate therapeutic strategies. Therefore, currently, cardiac patient management cannot ignore the complete and precise information provided by non-invasive diagnostic methods such as echocardiography, cardiac magnetic resonance imaging, cardio CT, and nuclear cardiology, which is useful to define the correct diagnosis and make an adequate prognostic stratification. With the expansion of imaging options and the paradigmatic shift to multimodality imaging, we need to focus and expand our research efforts to help identify areas of CV medicine where imaging adds value by improving diagnosis and the prediction of therapeutic benefit.

Dr. Ilaria Dentamaro
Guest Editor

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Keywords

  • cardiac imaging
  • echocardiography
  • cardiovascular magnetic resonance imaging
  • cardio CT
  • nuclear cardiology

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Published Papers (1 paper)

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Research

12 pages, 1687 KiB  
Article
Does Left Ventricular Rotational Mechanics Depend on Aortic Valve Annular Dimensions in Healthy Adults?—A Three-Dimensional Speckle-Tracking Echocardiography-Derived Analysis from the MAGYAR-Healthy Study
by Attila Nemes, Nóra Ambrus and Csaba Lengyel
Biomedicines 2025, 13(4), 817; https://doi.org/10.3390/biomedicines13040817 - 28 Mar 2025
Cited by 1 | Viewed by 278
Abstract
Introduction. There is a balanced relationship between the left ventricle (LV), the aortic valve and the aorta, the functioning of which is essential for optimal circulation. Associations between simultaneously assessed LV rotational mechanics and aortic valve annular (AVA) dimensions respecting the cardiac cycle [...] Read more.
Introduction. There is a balanced relationship between the left ventricle (LV), the aortic valve and the aorta, the functioning of which is essential for optimal circulation. Associations between simultaneously assessed LV rotational mechanics and aortic valve annular (AVA) dimensions respecting the cardiac cycle have never been assessed in clinical circumstances in healthy individuals by three-dimensional speckle-tracking echocardiography (3DSTE). The present study aimed to perform an extensive investigation in order to clarify their possible associations. Methods. The present study comprised 111 healthy individuals (mean age 35.3 ± 12.0 years, 69 males). Results. With increase in end-diastolic AVA area, tendentious increase in apical LV rotation and consequential LV twist could be detected. Basal and apical rotations and LV twist were tendentiously higher in case of mean end-systolic AVA area compared to lower/higher than mean end-systolic AVA area. With increase in basal LV rotation, tendentious decrease in end-diastolic AVA dimensions could be detected. End-systolic AVA dimensions were tendentiously smaller in case of mean basal LV rotation compared to lower/higher than mean basal LV rotations. With increase in apical LV rotation, tendentious increase in end-diastolic AVA dimensions could be detected. End-systolic AVA dimensions were tendentiously higher in case of mean apical LV rotation compared to lower/higher than mean apical LV rotations. Conclusions. No obvious significant association could be detected between simultaneously assessed LV rotational mechanics and AVA dimensions respecting the cardiac cycle in healthy adults. Full article
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