Special Issue "The Chemical Biology Research in France"
Deadline for manuscript submissions: 1 September 2021.
Chemistry at the interface of biology has played an important role in research in France since the end of the 19th century with the discoveries made by Louis Pasteur and their application to medicine and biotechnology. Chemical biology opens many possibilities for innovative findings and to develop new cutting-edge technologies to understand biology and discover, for example, new treatments for human diseases or new agronomical applications. The development of chemical reactions that occur in living systems has been a breakthrough and has enabled the observation and study of all types of biomolecules in living systems. An important application is detection: these chemical tools allow the detection and following of biological macromolecules, events and organisms in living cells and animals. With the implementation of the “omics” approaches and phenotypic technologies, chemical biology has revealed large numbers of uncharacterized potential drug targets that can be addressed with chemical probes. Chemical probes can reveal the function of a specific biomolecule without suppressing it. The effect is rapid, potentially reversible, and does not necessarily disrupt the entire interactome of the biomolecule in the biological context. Thus, they constitute a valuable toolbox for in detail studies of biological processes. Notably, when combined with a medicinal chemistry program, chemical probes can favour the emergence of drug candidates. Another explored area is the chemical modulation of biomolecules that can for example trigger the immune response and open the way to new therapeutic strategies. The present Special Issue is aimed at covering novel developments of chemical tools and chemical probes ongoing in French laboratories and their applications.
Dr. Paola Arimondo
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- chemical biology
- chemical tools
- drug discovery
- mechanism of action
- novel targets