Skip to Content
You are currently on the new version of our website. Access the old version .

5,342 Results Found

  • Article
  • Open Access
1 Citations
1,256 Views
14 Pages

22 March 2025

Seeking the alternative working pairs used in absorption refrigeration cycles is one of the main issues in refrigeration fields due to the drawbacks of traditional H2O/LiBr and NH3/H2O, such as corrosion, crystallization, and toxicity. The imidazoliu...

(This article belongs to the Special Issue Phase Equilibrium in Chemical Processes: Experiments and Modeling)
  • Article
  • Open Access
5 Citations
2,421 Views
15 Pages

Investigating the Role of the Zinc Finger Protein ZC2HC1C on Autism Spectrum Disorder Susceptibility

  • Simone Treccarichi,
  • Mirella Vinci,
  • Antonino Musumeci,
  • Rosanna Galati Rando and ,
  • Carla Papa,
  • Salvatore Saccone,
  • Concetta Federico,
  • Pinella Failla,
  • Martino Ruggieri and
  • Andrea Praticò
  • + 7 authors+ 2 authors

24 March 2025

Background and Objectives: Zinc finger proteins are important transcription factors that regulate gene expression and play a critical role in neurodevelopment including autism spectrum disorders (ASDs). They are involved in a variety of cellular proc...

(This article belongs to the Section Genetics and Molecular Medicine)
  • Article
  • Open Access
20 Citations
5,308 Views
17 Pages

26 February 2021

Atopic dermatitis (AD) is a chronic cutaneous disorder that is characterized by severe eczematous inflammation, swelling, and lichenification. Activation of T helper (Th)-22 cells by allergens leads to epidermal hyperplasia with hyperkeratosis at the...

(This article belongs to the Section Biochemistry)
  • Communication
  • Open Access
9 Citations
5,481 Views
7 Pages

11 October 2018

HcDNAV (a type species of Genus Dinodnavirus) is a large double-stranded DNA virus, which lytically infects the bloom-forming marine microalga Heterocapsa circularisquama Horiguchi (Dinophyceae). In the present study, detailed observation of the HcDN...

(This article belongs to the Special Issue Algae Virus)
  • Article
  • Open Access
31 Citations
5,889 Views
11 Pages

The Heavy Chain 4F2hc Modulates the Substrate Affinity and Specificity of the Light Chains LAT1 and LAT2

  • Satish Kantipudi,
  • Jean-Marc Jeckelmann,
  • Zöhre Ucurum,
  • Patrick D. Bosshart and
  • Dimitrios Fotiadis

14 October 2020

The human L-type amino acid transporters LAT1 and LAT2 mediate the transport of amino acids and amino acid derivatives across plasma membranes in a sodium-independent, obligatory antiport mode. In mammalian cells, LAT1 and LAT2 associate with the typ...

(This article belongs to the Special Issue Amino Acids Transport and Metabolism 3.0)
  • Article
  • Open Access
22 Citations
5,572 Views
40 Pages

30 July 2021

The nuclear basket (NB) scaffold, a fibrillar structure anchored to the nuclear pore complex (NPC), is regarded as constructed of polypeptides of the coiled-coil dominated protein TPR to which other proteins can bind without contributing to the NB’s...

(This article belongs to the Section Cell Nuclei: Function, Transport and Receptors)
  • Article
  • Open Access
3 Citations
1,962 Views
17 Pages

Genome-Wide Identification, Characterization, and Comparison of C3HC4 Family Genes in Salt Tolerance Between Barley and Rice

  • Kerun Chen,
  • Shuai Wang,
  • Xiaohan Xu,
  • Xintong Zheng and ,
  • Hongkai Wu,
  • Linzhou Huang,
  • Liping Dai,
  • Chenfang Zhan,
  • Dali Zeng and
  • Liangbo Fu
  • + 5 authors+ 0 author

3 August 2025

Soil salinization constitutes a major constraint on global agricultural production, with marked divergence in salt adaptation strategies between salt-tolerant barley (Hordeum vulgare) and salt-sensitive rice (Oryza sativa). This study systematically...

(This article belongs to the Special Issue Cell Physiology and Stress Adaptation of Crops)
  • Article
  • Open Access
22 Citations
5,714 Views
21 Pages

Validation of CD98hc as a Therapeutic Target for a Combination of Radiation and Immunotherapies in Head and Neck Squamous Cell Carcinoma

  • Ayşe Sedef Köseer,
  • Liliana R. Loureiro,
  • Justyna Jureczek,
  • Nicola Mitwasi and ,
  • Karla Elizabeth González Soto,
  • Julia Aepler,
  • Tabea Bartsch,
  • Anja Feldmann,
  • Leoni A. Kunz-Schughart and
  • Anna Dubrovska
  • + 9 authors+ 4 authors

25 March 2022

Most patients with head and neck squamous cell carcinomas (HNSCC) are diagnosed at a locally advanced stage and show heterogeneous treatment responses. Low SLC3A2 (solute carrier family 3 member 2) mRNA and protein (CD98hc) expression levels are asso...

(This article belongs to the Special Issue Combined CAR T-cell Therapies: A Next Step towards Precision Oncology)
  • Article
  • Open Access
2 Citations
1,240 Views
17 Pages

1 December 2025

The potyvirus helper component proteinase (HcPro) is a multifunctional protein, with one of its most documented functions being host antiviral RNA silencing suppression. This study shows that the HcPro of potato virus Y (PVY), an important member of...

(This article belongs to the Special Issue Viral Infections and Viral Pathogenesis)
  • Article
  • Open Access
4 Citations
976 Views
12 Pages

HC-Pro Disrupts miR319–TCP Regulatory Pathways to Induce Sterility in Transgenic Plants

  • Taicheng Jin,
  • Weiyan Wang,
  • Jiaxue Yu,
  • Zhuyi Xiao and ,
  • Yushuo Li,
  • Xu Sun and
  • Liping Yang
  • + 2 authors+ 0 author

30 October 2025

Helper component-proteinase (HC-Pro), encoded by tobacco vein banding mosaic virus (TVBMV), can cause various viral symptoms and even abortion. HC-Pro counteracts host-mediated inhibition by interfering with the accumulation of microRNAs (miRNAs) and...

(This article belongs to the Special Issue Physiology and Molecular Biology of Plant Stress Tolerance: 3rd Edition)
  • Article
  • Open Access
12 Citations
5,264 Views
13 Pages

25 September 2020

Heterodimeric amino acid transporters (HATs) are protein complexes mediating the transport of amino acids and derivatives thereof across biological membranes. HATs are composed of two subunits, a heavy and a light chain subunit belonging to the solut...

(This article belongs to the Special Issue Amino Acids Transport and Metabolism 3.0)
  • Article
  • Open Access
27 Citations
4,692 Views
20 Pages

Robust Adaptive HCS MPPT Algorithm-Based Wind Generation System Using Model Reference Adaptive Control

  • Ziyad A. Alrowaili,
  • Mustafa M. Ali,
  • Abdelraheem Youssef,
  • Hossam H. H. Mousa and ,
  • Ahmed S. Ali,
  • Gamal T. Abdel-Jaber,
  • Mohammed Ezzeldien and
  • Fatma Gami
  • + 3 authors+ 0 author

30 July 2021

To treat the stochastic wind nature, it is required to attain all available power from the wind energy conversion system (WECS). Therefore, several maximum power point tracking (MPPT) techniques are utilized. Among them, hill-climbing search (HCS) te...

(This article belongs to the Section Electronic Sensors)
  • Article
  • Open Access
4 Citations
1,934 Views
18 Pages

Role of Bean Yellow Mosaic Virus P1 and HC-Pro in Enhancing Gene Expression and Suppressing RNA Silencing in Nicotiana benthamiana

  • Sunmee Choi,
  • Suk Hyun Kwon,
  • Gi Seok Kwon,
  • Ho Seong Choi and ,
  • Hyo Hyun Seo,
  • Young Soon Kim,
  • Jeong Hun Lee,
  • Won Kyong Cho and
  • Sang Hyun Moh
  • + 4 authors+ 0 author

15 March 2025

Potyviruses, a major group of plant viruses, utilize HC-Pro, a multifunctional protein, to suppress RNA silencing, a crucial plant defense mechanism. While HC-Pro’s role in RNA silencing suppression has been studied in several potyviruses, the...

(This article belongs to the Section Plant Science)
  • Article
  • Open Access
22 Citations
5,403 Views
21 Pages

Investigating the Viral Suppressor HC-Pro Inhibiting Small RNA Methylation through Functional Comparison of HEN1 in Angiosperm and Bryophyte

  • Neda Sanobar,
  • Pin-Chun Lin,
  • Zhao-Jun Pan,
  • Ru-Ying Fang and ,
  • Veny Tjita,
  • Fang-Fang Chen,
  • Hao-Ching Wang,
  • Huang-Lung Tsai,
  • Shu-Hsing Wu and
  • Shih-Shun Lin
  • + 7 authors+ 2 authors

15 September 2021

In plants, HEN1-facilitated methylation at 3′ end ribose is a critical step of small-RNA (sRNA) biogenesis. A mutant of well-studied Arabidopsis HEN1 (AtHEN1), hen1-1, showed a defective developmental phenotype, indicating the importance of sRNA meth...

(This article belongs to the Special Issue State-of-the-Art Plant-Virus Interactions in Asia)
  • Review
  • Open Access
94 Citations
11,427 Views
15 Pages

6 July 2020

With the frequent outbreaks of emerging infectious diseases in recent years, an effective broad-spectrum antiviral drug is becoming an urgent need for global public health. Cholesterol-25-hydroxylase (CH25H) and its enzymatic products 25-hydroxychole...

(This article belongs to the Section Viral Immunology, Vaccines, and Antivirals)
  • Article
  • Open Access
10 Citations
3,545 Views
26 Pages

Investigation of P1/HC-Pro-Mediated ABA/Calcium Signaling Responses via Gene Silencing through High- and Low-Throughput RNA-seq Approaches

  • Yen-Hsin Chiu,
  • Yu-Ling Hung,
  • Hsin-Ping Wang,
  • Wei-Lun Wei and ,
  • Qian-Wen Shang,
  • Thanh Ha Pham,
  • Chien-Kang Huang,
  • Zhao-Jun Pan and
  • Shih-Shun Lin
  • + 4 authors+ 0 author

23 November 2021

The P1/HC-Pro viral suppressor of potyvirus suppresses posttranscriptional gene silencing (PTGS). The fusion protein of P1/HC-Pro can be cleaved into P1 and HC-Pro through the P1 self-cleavage activity, and P1 is necessary and sufficient to enhance P...

(This article belongs to the Special Issue State-of-the-Art Plant-Virus Interactions in Asia)
  • Article
  • Open Access
15 Citations
6,500 Views
10 Pages

21 February 2019

Heteromeric amino acid transporters (HATs) are protein complexes that catalyze the transport of amino acids across plasma membranes. HATs are composed of two subunits, a heavy and a light subunit, which belong to the solute carrier (SLC) families SLC...

(This article belongs to the Special Issue Amino Acids Transport and Metabolism 2.0)
  • Review
  • Open Access
16 Citations
4,665 Views
20 Pages

Contribution of LAT1-4F2hc in Urological Cancers via Toll-like Receptor and Other Vital Pathways

  • Xue Zhao,
  • Shinichi Sakamoto,
  • Maihulan Maimaiti,
  • Naohiko Anzai and
  • Tomohiko Ichikawa

4 January 2022

Tumor cells are known for their ability to proliferate. Nutrients are essential for rapidly growing tumor cells. In particular, essential amino acids are essential for tumor cell growth. Tumor cell growth nutrition requires the regulation of membrane...

  • Feature Paper
  • Article
  • Open Access
44 Citations
6,636 Views
20 Pages

Segmentation Detection Method for Complex Road Cracks Collected by UAV Based on HC-Unet++

  • Hongbin Cao,
  • Yuxi Gao,
  • Weiwei Cai,
  • Zhuonong Xu and
  • Liujun Li

10 March 2023

Road cracks are one of the external manifestations of safety hazards in transportation. At present, the detection and segmentation of road cracks is still an intensively researched issue. With the development of image segmentation technology of the c...

(This article belongs to the Special Issue Intelligent Image Processing and Sensing for Drones)
  • Article
  • Open Access
3 Citations
6,525 Views
13 Pages

Pichia pastoris and the Recombinant Human Heterodimeric Amino Acid Transporter 4F2hc-LAT1: From Clone Selection to Pure Protein

  • Satish Kantipudi,
  • Daniel Harder,
  • Sara Bonetti,
  • Dimitrios Fotiadis and
  • Jean-Marc Jeckelmann

Heterodimeric amino acid transporters (HATs) are protein complexes composed of two subunits, a heavy and a light subunit belonging to the solute carrier (SLC) families SLC3 and SLC7. HATs transport amino acids and derivatives thereof across the plasm...

(This article belongs to the Section Biochemical and Chemical Analysis & Synthesis)
  • Article
  • Open Access
6 Citations
3,823 Views
26 Pages

Comprehensive Characterization of the C3HC4 RING Finger Gene Family in Potato (Solanum tuberosum L.): Insights into Their Involvement in Anthocyanin Biosynthesis

  • Limin Chen,
  • Yuanming Li,
  • Jinyong Zhu,
  • Zhitao Li and ,
  • Weilu Wang,
  • Zheying Qi,
  • Dechen Li,
  • Panfeng Yao,
  • Zhenzhen Bi and
  • Zhen Liu
  • + 7 authors+ 2 authors

8 February 2024

The C3HC4 RING finger gene (RING-HC) family is a zinc finger protein crucial to plant growth. However, there have been no studies on the RING-HC gene family in potato. In this study, 77 putative StRING-HCs were identified in the potato genome and gro...

(This article belongs to the Collection Advances in Molecular Plant Sciences)
  • Article
  • Open Access
328 Views
16 Pages

Expression Profiling and Characterization of HcTGA5 Gene in Kenaf Under Hormonal Treatments and Its Association with Resistance to Root-Knot Nematode

  • Jiguang Luo,
  • Xuewu Wang,
  • Xiangping Zeng,
  • Zhixiang Zhao and ,
  • Miancai Chen,
  • Meiying Fu and
  • Huifang Wang
  • + 2 authors+ 0 author

16 September 2026

Kenaf (Hibiscus cannabinus L.), a member of the Malvaceae family, has gained increasing research interest owing to its therapeutic attributes. Among pathogens affecting tropical kenaf cultivation, Meloidogyne enterolobii is the most economically dest...

(This article belongs to the Special Issue Molecular Breeding and Comprehensive Utilization of Economic Crops)
  • Article
  • Open Access
9 Citations
5,146 Views
12 Pages

28 December 2018

This study aimed to compare age-dependent changes in the relative expression of genes encoding myosin heavy chain (MyHC) isoforms and selected lipid metabolism-related genes in the longissimus dorsi muscle of wild pigs (WPs) and domestic pigs (DPs)....

(This article belongs to the Section Pigs)
  • Article
  • Open Access
9 Citations
2,270 Views
15 Pages

Key Role of Corncob Based-Hydrochar (HC) in the Enhancement of Visible Light Photocatalytic Degradation of 2,4-Dichlorophenoxyacetic Acid Using a Derivative of ZnBi-Layered Double Hydroxides

  • Ngo Thi Tuong Vy,
  • Dang Nguyen Nha Khanh,
  • Nguyen Ngoc Nghia,
  • Le Hai Khoa and ,
  • Pham Tuan Nhi,
  • Le Xuan Hung,
  • Doan Thi Minh Phuong and
  • Nguyen Thi Kim Phuong
  • + 3 authors+ 0 author

16 July 2023

A superior heterojunction of HC-ZnBi-LDO was synthesized in two steps, namely hydrothermal carbonization, followed by co-precipitation. The 2% HC-ZnBi-LDO heterojunction photocatalysts could degrade over 90.8% of 30 mg/L 2,4-dichlorophenoxyacetic aci...

(This article belongs to the Special Issue The 15th Anniversary of Materials—Recent Advances in Catalytic Materials)
  • Article
  • Open Access
13 Citations
4,198 Views
17 Pages

7 February 2020

The loose accumulation CAUSED by landslide, collapse, debris flow, and mine blasting, exerts considerable negative influence to human activities. Besides, it can easily trigger secondary disaster under inner and outer geological conditions. Extractio...

(This article belongs to the Section Remote Sensors)
  • Article
  • Open Access
4 Citations
2,517 Views
14 Pages

12 November 2021

Prediction of soft soil settlement is an important research topic in the field of civil engineering, and the least square support vector machine is one of the commonly used prediction methods at present. Nonetheless, the existing LSSVM models have pr...

(This article belongs to the Section Civil Engineering)
  • Technical Note
  • Open Access
38 Citations
9,711 Views
22 Pages

Land Cover Mapping in Southwestern China Using the HC-MMK Approach

  • Guangbin Lei,
  • Ainong Li,
  • Jinhu Bian,
  • Zhengjian Zhang and ,
  • Huaan Jin,
  • Xi Nan,
  • Wei Zhao,
  • Jiyan Wang,
  • Xiaomin Cao and
  • Wenlan Feng
  • + 9 authors+ 4 authors

7 April 2016

Land cover mapping in mountainous areas is a notoriously challenging task due to the rugged terrain and high spatial heterogeneity of land surfaces as well as the frequent cloud contamination of satellite imagery. Taking Southwestern China (a typical...

  • Article
  • Open Access
7 Citations
5,206 Views
17 Pages

Upregulation of Transferrin Receptor 1 (TfR1) but Not Glucose Transporter 1 (GLUT1) or CD98hc at the Blood–Brain Barrier in Response to Valproic Acid

  • Steinunn Sara Helgudóttir,
  • Kasper Bendix Johnsen,
  • Lisa Greve Routhe,
  • Charlotte Laurfelt Munch Rasmussen and ,
  • Maj Schneider Thomsen and
  • Torben Moos
  • + 1 author+ 0 author

11 July 2024

Background: Transferrin receptor 1 (TfR1), glucose transporter 1 (GLUT1), and CD98hc are candidates for targeted therapy at the blood–brain barrier (BBB). Our objective was to challenge the expression of TfR1, GLUT1, and CD98hc in brain capilla...

(This article belongs to the Section Cellular Metabolism)
  • Article
  • Open Access
4 Citations
4,209 Views
13 Pages

Effect of Zinc Aluminum Magnesium Coating on Spot-Welding Joint Properties of HC340LAD + ZM Steel

  • Xiang Chen,
  • Xinjie Peng,
  • Xinjian Yuan,
  • Ziliu Xiong and ,
  • Yue Lu,
  • Shenghai Lu and
  • Jian Peng
  • + 2 authors+ 0 author

9 September 2022

Zn-Al-Mg (zinc, aluminum and magnesium)-coated steel is gradually replacing traditional hot-dip galvanized steel due to its excellent corrosion resistance, self-healing properties and good surface hardness. However, the effect of Zn-Al-Mg coating on...

(This article belongs to the Special Issue Metal-Based Composite Materials: Preparation, Structure, Properties, and Applications)
  • Article
  • Open Access
5 Citations
4,423 Views
15 Pages

Inhibition of Canonical Transient Receptor Potential Channels 4/5 with Highly Selective and Potent Small-Molecule HC-070 Alleviates Mechanical Hypersensitivity in Rat Models of Visceral and Neuropathic Pain

  • Niina Jalava,
  • Janne Kaskinoro,
  • Hugh Chapman,
  • Miguel Morales and ,
  • Hanna Metsänkylä,
  • Satu-Maarit Heinonen and
  • Ari-Pekka Koivisto
  • + 2 authors+ 0 author

8 February 2023

Transient receptor potential channels C4/C5 are widely expressed in the pain pathway. Here, we studied the putative analgesic efficacy of the highly selective and potent TRPC4/C5 antagonist HC-070 in rats. Inhibitory potency on human TRPC4 was assess...

(This article belongs to the Special Issue Targeting TRP Channels for Pain, Itch and Inflammation Relief)
  • Article
  • Open Access
2,673 Views
18 Pages

13 December 2023

As air pollution becomes more and more serious, PM2.5 is the primary pollutant, inevitably attracts wide public attention. Therefore, a novel PM2.5 concentration forecasting method based on linear fuzzy information granule_dynamic time warping_hierar...

(This article belongs to the Special Issue Computational Statistics and Its Applications)
  • Article
  • Open Access
603 Views
19 Pages

Cyber wargaming serves as a core tool for simulating cyber confrontations and supporting operational decision verification. Existing multi-agent methods face issues such as the absence of cross-level mechanisms and poor adaptability to dynamic enviro...

  • Article
  • Open Access
24 Citations
6,867 Views
18 Pages

13 August 2020

Soybean mosaic virus (SMV), which belongs to the Potyviridae, causes significant reductions in soybean yield and seed quality. In this study, both tag-free and reporter gene green fluorescent protein (GFP)-containing infectious clones for the SMV N1...

(This article belongs to the Special Issue Plant Virus Pathogenesis and Disease Control)
  • Proceeding Paper
  • Open Access
2 Citations
3,503 Views
4 Pages

Design and Fabrication of an Automated Water-Jet Robot for PV Panel Cleaning Using an Arduino-Assisted HC-05 Bluetooth Module

  • Ramisetty Umamaheswari,
  • Yeluri Sai Sanjana,
  • Guntreddi Ritendra Kumar,
  • Rayapureddi Dileep Naidu and ,
  • Appana Sai Shashank,
  • Eti Venkata Sai Shashank and
  • Navara Pavan Manikanta Srinivasa Rao
  • + 2 authors+ 0 author

In the current scenario, renewable energy resources play a vital role in developing countries. Photovoltaic panel-based power plants have great significance for the production of electrical energy, due to automated transitions, easy interaction, and...

(This article belongs to the Proceedings of The 5th International Conference on Innovative Product Design and Intelligent Manufacturing Systems (IPDIMS 2023))
  • Article
  • Open Access
1 Citations
2,109 Views
14 Pages

31 July 2024

East Asian Passiflora virus (EAPV) causes passionfruit woodiness disease, a major threat limiting passionfruit production in eastern Asia, including Taiwan and Vietnam. In this study, an infectious cDNA clone of a Taiwanese severe isolate EAPV-TW was...

(This article belongs to the Special Issue Crop Resistance to Viral Infections)
  • Article
  • Open Access
764 Views
25 Pages

16 July 2026

In this study, HC420LA steel plates joined by gas metal arc welding (MAG), manual laser welding (ML), and robotic laser welding (RL) were comparatively examined under heat input (HI) levels obtained from an active production line exhibiting weld defe...

(This article belongs to the Special Issue Advances in High-Performance Alloys)
  • Article
  • Open Access
14 Citations
2,649 Views
13 Pages

Identification and Functional Analysis of V-ATPaseA and C Genes in Hyphantria cunea

  • Xiaojie Wang,
  • Dan Zhao,
  • Qian Wang,
  • Yanan Liu and ,
  • Xiujun Lu and
  • Wei Guo
  • + 1 author+ 0 author

10 July 2024

Vacuolar (H+)-ATPases (V-ATPases) are ATP-driven proton pumps that play multifaceted roles across various organisms. Despite their widespread significance, the functional implications of V-ATPase genes in Hyphantria cunea, an invasive forest pest wit...

(This article belongs to the Section Insect Molecular Biology and Genomics)
  • Article
  • Open Access
7 Citations
5,377 Views
19 Pages

Transcriptome of the Aedes aegypti Mosquito in Response to Human Complement Proteins

  • Gloria I. Giraldo-Calderón,
  • Arley Calle-Tobón,
  • Paula Rozo-López,
  • Tonya M. Colpitts and ,
  • Yoonseong Park,
  • Guillermo L. Rua-Uribe and
  • Berlin Londono-Renteria
  • + 2 authors+ 0 author

9 September 2020

Aedes aegypti is the primary mosquito vector of several human arboviruses, including the dengue virus (DENV). Vector control is the principal intervention to decrease the transmission of these viruses. The characterization of molecules involved in th...

(This article belongs to the Special Issue Molecular Research on Vector-Borne Diseases of Medical Interest: From Bench to Application)
  • Article
  • Open Access
54 Citations
5,183 Views
21 Pages

Genome-Wide Analysis and Characterization of the Aux/IAA Family Genes Related to Floral Scent Formation in Hedychium coronarium

  • Yanguo Ke,
  • Farhat Abbas,
  • Yiwei Zhou,
  • Rangcai Yu and ,
  • Yuechong Yue,
  • Xinyue Li,
  • Yunyi Yu and
  • Yanping Fan
  • + 3 authors+ 0 author

Auxin plays a key role in different plant growth and development processes, including flower opening and development. The perception and signaling of auxin depend on the cooperative action of various components, among which auxin/indole-3-acetic acid...

(This article belongs to the Section Molecular Genetics and Genomics)
  • Article
  • Open Access
1 Citations
4,873 Views
12 Pages

Evaluation of External Memory Access Performance on a High-End FPGA Hybrid Computer

  • Konstantinos Kalaitzis,
  • Evripidis Sotiriadis,
  • Ioannis Papaefstathiou and
  • Apostolos Dollas

The motivation of this research was to evaluate the main memory performance of a hybrid super computer such as the Convey HC-x, and ascertain how the controller performs in several access scenarios, vis-à-vis hand-coded memory prefetches. Such memory...

(This article belongs to the Section Computational Engineering)
  • Article
  • Open Access
22 Citations
5,575 Views
16 Pages

The Oxysterol 25-Hydroxycholesterol Inhibits Replication of Murine Norovirus

  • Ghada T. Shawli,
  • Oluwapelumi O. Adeyemi,
  • Nicola J. Stonehouse and
  • Morgan R. Herod

24 January 2019

Cholesterol, an essential component of mammalian cells, is also an important factor in the replicative-cycles of several human and animal viruses. The oxysterol, 25-hydroxycholesterol, is produced from cholesterol by the enzyme, cholesterol 25-hydrox...

(This article belongs to the Special Issue Noroviruses)
  • Article
  • Open Access
1 Citations
1,352 Views
11 Pages

9 September 2025

This study used Houttuynia cordata as the precursor to prepare high fluorescence quantum yield carbon quantum dots (Hc-CQDs) by a simple hydrothermal method. The surface of the Hc-CQDs contained abundant functional groups, such as carboxyl, hydroxyl,...

(This article belongs to the Section Materials Chemistry)
  • Article
  • Open Access
10 Citations
3,827 Views
22 Pages

Integrated Hemicellulose Extraction and Papermaking Fiber Production from Agro-Waste Biomass

  • Adrian Cătălin Puițel,
  • Cătălin Dumitrel Balan,
  • Gabriela-Liliana Ailiesei,
  • Elena Niculina Drăgoi and
  • Mircea Teodor Nechita

1 December 2023

The present study deals with the valorization of corn stalks in an integrated processing strategy targeting two products: extracted hemicelluloses (HC) and papermaking fibers. Preliminary trials were conducted to assess the individual or the combined...

(This article belongs to the Special Issue Advances in Natural Polymers: Extraction Methods and Applications)
  • Review
  • Open Access
22 Citations
4,186 Views
18 Pages

Calcium Regulation of Connexin Hemichannels

  • Erva Bayraktar,
  • Diego Lopez-Pigozzi and
  • Mario Bortolozzi

Connexin hemichannels (HCs) expressed at the plasma membrane of mammalian cells are of paramount importance for intercellular communication. In physiological conditions, HCs can form gap junction (GJ) channels, providing a direct diffusive path betwe...

(This article belongs to the Special Issue Gap Junction Channels and Hemichannels in Health and Disease: 2nd Edition)
  • Article
  • Open Access
1,726 Views
6 Pages

Our putpose is to make decision of intrauterine growth retardation (IUGR) through single and multiple ultrasonographic fetal growth assessments using a neural network (NN). This study was undertaken to show if a feedforward NN can learn nominal growt...

  • Article
  • Open Access
8 Citations
2,873 Views
13 Pages

16 November 2021

It is well known that reduced contractile activity of the main postural soleus muscle during long-term bedrest, immobilization, hindlimb unloading, and space flight leads to increased expression of fast isoforms and decreased expression of the slow i...

(This article belongs to the Special Issue Drug Insight: Histone Deacetylase (HDAC) Inhibitors)
  • Article
  • Open Access
824 Views
15 Pages

Integrated Transcriptomic Analysis and Functional Validation Identify CNTN1 as a Novel Metastatic Driver in Hilar Cholangiocarcinoma

  • Xiangming Ding,
  • Chiyu Cai,
  • Yuanxiang Lu,
  • Zipeng Wang and ,
  • Junjing Hou,
  • Yushu Xue,
  • Luyun Zhang,
  • Meng Xie and
  • Dongxiao Li
  • + 4 authors+ 0 author

Background: Hilar cholangiocarcinoma (HC) is a highly aggressive malignancy with a poor prognosis, highlighting the urgent need to elucidate its molecular drivers. This study aimed to systematically identify and functionally validate key genes and pa...

(This article belongs to the Section Molecular Genetics and Genetic Diseases)
  • Article
  • Open Access
8 Citations
6,117 Views
11 Pages

To investigate the effects of a high-carbohydrate and low-fat (HC/LF) diet on plasma lipids and apolipoproteins (Apos) of healthy Chinese Han youth with different genotypes of lipoprotein lipase gene (LPL) rs326, 56 subjects were given a washout diet...

  • Article
  • Open Access
20 Citations
5,634 Views
20 Pages

Identification and Characterization of Hyphantria cunea Aminopeptidase N as a Binding Protein of Bacillus thuringiensis Cry1Ab35 Toxin

  • Yakun Zhang,
  • Dan Zhao,
  • Xiaoping Yan,
  • Wei Guo and ,
  • Yajun Bao,
  • Wei Wang and
  • Xiaoyun Wang
  • + 2 authors+ 0 author

30 November 2017

The fall webworm, Hyphantria cunea (Drury) is a major invasive pest in China. Aminopeptidase N (APN) isoforms in lepidopteran larvae midguts are known for their involvement in the mode of action of insecticidal crystal (Cry) proteins from Bacillus th...

(This article belongs to the Special Issue Molecular Entomology of Insects of Economic Importance)
  • Article
  • Open Access
5 Citations
3,050 Views
16 Pages

Identification and Functional Analysis of the Cell Proliferation Regulator, Insulin-like Growth Factor 1 (IGF1) in Freshwater Pearl Mussel (Hyriopsis cumingii)

  • Xuenan Li,
  • Shangle Feng,
  • He Wang,
  • Xiaoya Shen and ,
  • Yige Chen,
  • Xingrong Xuan,
  • Yuanshuai Fu,
  • Zhiyi Bai and
  • Wenjuan Li
  • + 4 authors+ 0 author

19 September 2022

Insulin-like growth factor 1 (IGF1) plays an important regulatory role in the regulation of growth, differentiation, and anabolism in a variety of cells. In this study, the full-length cDNA of the IGF1 gene was cloned from Hyriopsis cumingii, named H...

of 107