Possible enhancements of DNA damage with light of different wavelengths and ionizing radiation (Rhenium-188—a high energy beta emitter (Re-188)) on plasmid DNA and FaDu cells via psoralen were investigated. The biophysical experimental setup co...
This work investigates the proposed enhanced efficacy of photodynamic therapy (PDT) by activating photosensitizers (PSs) with Cherenkov light (CL). The approaches of Yoon et al. to test the effect of CL with external radiation were taken up and refin...
The SPHERE project studies primary cosmic rays by detection of the Cherenkov light of extensive air showers reflected from the snow covered surface of the earth. Measurements with the aerial-based detector SPHERE-2 were performed in 2011–2013....
This work presents the development of a 64-channel application-specific integrated circuit (ASIC), implemented to detect the optical Cherenkov light from sub-orbital and orbital altitudes. These kinds of signals are generated by ultra-high energy cos...
Different applications require different customizations of silicon photomultiplier (SiPM) technology. We present a review on the latest SiPM technologies developed at Fondazione Bruno Kessler (FBK, Trento), characterized by a peak detection efficienc...
This work describes the development of the Multi-channel Integrated Zone-sampling Analogue-memory based Readout (MIZAR) ASIC. This 64-channel chip was designed as part of NASA’s POEMMA Balloon with RADIO (PBR) mission, which aims to detect Ultr...
Precision measurements of Z, W, and H decays at the next generation of circular lepton colliders will require excellent energy resolution for both electromagnetic and hadronic showers. The resolution is limited by event-to-event fluctuations in the s...
The Cherenkov effect, whereby a charged particle emits light when traveling faster than the phase velocity of light in a dielectric medium, is widely employed in particle identification techniques. However, Cherenkov light yield is relatively low, ty...
Ground-based observations of Very High Energy (VHE) gamma rays from extreme astrophysical sources are significantly influenced by atmospheric conditions. This is due to the atmosphere being an integral part of the detector when utilizing Imaging Atmo...
The JEM-EUSO program aims to study ultra-high energy cosmic rays from space. To achieve this goal, it has realized a series of experiments installed on the ground (EUSO-TA), various on stratospheric balloons (with the most recent one EUSO-SPB2), and...
Future space detectors for Ultra High Energy neutrinos and cosmic rays will utilize Cherenkov telescopes to detect forward-beamed Cherenkov light produced by charged particles in Extensive Air Showers (EASs). A Cherenkov detector can be equipped with...
We derive closed analytical formulae for the power emitted by moving charged particles in a uniaxial wire medium by means of an eigenfunction expansion. Our analytical expressions demonstrate that, in the absence of material dispersion, the stopping...
This paper presents the technical design of the pathfinder Barcelona Raman LIDAR (pBRL) for the northern site of the Cherenkov Telescope Array Observatory (CTAO-N) located at the Roque de los Muchachos Observatory (ORM). The pBRL is developed for con...
The aim of this work is to develop high-precision time-of-flight (TOF) devices based on high-refractive-index solid Cherenkov radiators read out by silicon photomultipliers (SiPMs). Cherenkov light is prompt and, therefore, ideal for reaching the int...
In a recent paper, the authors discussed the feasibility study of an innovative technique based on the directionality of Cherenkov light produced in a transparent material to improve the signal to noise ratio in muon imaging applications. In particul...
The temporal profile measurement for ultra-short electron bunches is one of the key issues for accelerator-based coherent light sources. A bunch length measurement system using Cherenkov radiation (CR) is under development at the Research Center for...
Recent observations have confirmed that Gamma-Ray Burst (GRB) afterglows produce Very High-Energy radiation (VHE,
Observations of Very High Energy (VHE) gamma ray sources using the ground-based Imaging Atmospheric Cherenkov Telescopes (IACTs) play a pivotal role in understanding the non-thermal energetic phenomena and acceleration processes under extreme astroph...
Imaging Atmospheric Cherenkov Telescopes (IACTs) have revolutionized our understanding of the universe at very high energies (VHEs), enabling groundbreaking discoveries of extreme astrophysical phenomena. These instruments capture the brief flashes o...
Blazars like Markarian 421 or Markarian 501 are active galactic nuclei (AGN), with their jets orientated towards the observer. They are among the brightest objects in the very high energy (VHE) gamma ray regime (>100 GeV). Their emitted gamma-ray...
The KM3NeT deep-sea neutrino telescope will use thousands of Digital Optical Modules (DOMs) forming a 3D array to detect the Cherenkov’s light produced by the particles generated after a neutrino interaction in the medium. The DOMs are arranged in De...
Multifunctional optical devices are desirable at all times due to their features of flexibility and high efficiency. Based on the principle that the phase of excitation light can be transferred to the generated surface plasmon polaritons (SPPs), a pl...
NUSES is a pathfinder satellite project hosting two detectors: Ziré and Terzina. Ziré focuses on the study of protons and electrons below 250 MeV and MeV gamma rays. Terzina is dedicated to the detection of Cherenkov light produced by u...
Flux distribution is an important tool to understand the variability processes in active galactic nuclei. We now have available a great deal of observational evidences pointing towards the presence of log-normal components in the high energy light cu...
Scintillators play a key role in the detection chain of several applications which rely on the use of ionizing radiation, and it is often mandatory to extract and detect the generated scintillation light as efficiently as possible. Typical inorganic...
Positronium (Ps) is an unstable system created by the temporary combination of electrons and negative electrons, and Ps generation technology under resonance conditions at millimeter waves is emerging as a new research topic. In general, Ps can be ob...
Photodynamic therapy (PDT) involves the use of photosensitizers (PSs) that, upon activation by specific wavelengths of light, generate reactive oxygen species (ROS), including singlet oxygen (1O2) and hydroxyl radicals (·OH), within the target...
Translational photopharmacological applications are limited through irradiation by light showing wavelengths within the bio-optical window. To achieve sufficient tissue penetration, using wavelengths >500 nm is mandatory. Nevertheless, the majorit...
Radiological detection where Cherenkov residual background can be prominent requires scintillators with increased emission wavelength. Cherenkov residual background precludes the use of UV-emitting sensors such as plastic scintillators. However, the...
A new fibre-sampling dual-readout calorimeter prototype has been qualified on beam at two facilities (DESY and CERN) using electrons from 1 to 100 GeV. The prototype was designed to almost fully contain electromagnetic showers and a central module (h...
Malignant tumors rank as a leading cause of death worldwide. Accurate diagnosis and advanced treatment options are crucial to win battle against tumors. In recent years, Cherenkov luminescence (CL) has shown its technical advantages and clinical tran...
Twenty years ago, we started to apply quantum optics to the astronomical research carried out inside the Department of Physics and Astronomy and the INAF Astronomical Observatory in Padova, Italy. The initial activities were stimulated by the project...
A conceptual design study is presented for a hemispherical, two-chamber water Cherenkov detector instrumented with bladder-embedded light traps. The detector consists of a rigid aluminium vessel enclosing a water volume that is divided into an outer,...
Clouds are essential for regulating the hydrological cycle and Earth’s radiation budget, and their fluctuations over the Tibetan Plateau (TP) have a significant effect on both regional climate dynamics and global atmospheric circulation. Using...
The Lorentz invariance violation (LIV) predicted by some quantum gravity theories would manifest as an energy-dependent speed of light, which may potentially distort the observed temporal profile of photons from astrophysical sources at cosmological...
K-EUSO (KLYPVE-EUSO) is a planned orbital mission aimed at studying ultra-high energy cosmic rays (UHECRs) by detecting fluorescence and Cherenkov light emitted by extensive air showers in the nocturnal atmosphere of Earth in the ultraviolet (UV) ran...
FLASH radiotherapy is an emerging radiotherapy technique used to spare normal tissues. It employs ultra-high dose rate radiation beams over 40 Gy/s, which is significantly higher than those of conventional radiotherapy. In this study, a fiber-optic r...
The radiation-induced emission (RIE) of Gd3+-doped sol–gel silica glass has been shown to have suitable properties for use in the dosimetry of beams of ionizing radiation in applications such as radiotherapy. Linear electron accelerators are co...
The study of Ultra-High-Energy Cosmic Rays is made possible by space telescopes that allow for the recording of signals generated by Extensive Air Showers (EAS) on the night side of the Earth’s atmosphere. One of the requirements for these tele...
The KM3NeT underwater neutrino telescope comprises thousands of optical modules forming 3D arrays to detect the Cherenkov light produced by particles generated after a neutrino interaction in the medium. The modules are arranged in detection units&md...
Gamma-ray bursts (GRBs) are the most luminous explosions in the Universe and are powered by ultra-relativistic jets. Their prompt
Blazars are variable at every timescale that has been observed, from minute-scale flares to secular trends spanning decades, and across the whole electromagnetic spectrum from radio to very-high-energy (VHE;
Investigations that were carried out over the last two decades with novel and more sensitive instrumentation have dramatically improved our knowledge of the more violent physical processes taking place in galactic and extra-galactic Black-Holes, Neut...
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Background/Objectives: Radiotherapy is a widely applied first-line clinical treatment modality of cancer. Copper–cysteamine (Cu-Cy) nanoparticles represent a new type of photosensitizer that demonstrates significant anti-tumor potential by X-ra...