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41 Results Found

  • Review
  • Open Access
644 Views
28 Pages

1 September 2026

IMGT®, the international information system® (IMGT), was created in 1989 by Marie-Paule Lefranc (Université de Montpellier and CNRS) in Montpellier, France, to deal with and to manage the huge diversity of immunoglobulins (IG) or antib...

(This article belongs to the Special Issue Feature Papers in Section "Biomacromolecules: Proteins, Nucleic Acids and Carbohydrates")
  • Article
  • Open Access
5 Citations
3,243 Views
25 Pages

Enhancing Instance Segmentation in Agriculture: An Optimized YOLOv8 Solution

  • Qiaolong Wang,
  • Dongshun Chen,
  • Wenfei Feng,
  • Liang Sun and
  • Gaohong Yu

4 September 2025

To address the limitations of traditional segmentation algorithms in processing complex agricultural scenes, this paper proposes an improved YOLOv8n-seg model. Building upon the original three detection layers, we introduce a dedicated layer for smal...

(This article belongs to the Section Smart Agriculture)
  • Article
  • Open Access
1 Citations
4,260 Views
34 Pages

Factor Investment or Feature Selection Analysis?

  • Jifang Mai,
  • Shaohua Zhang,
  • Haiqing Zhao and
  • Lijun Pan

24 December 2024

This study has made significant findings in A-share market data processing and portfolio management. Firstly, by adopting the Lasso method and CPCA framework, we effectively addressed the problem of multicollinearity among feature indicators, with th...

(This article belongs to the Special Issue Advanced Statistical Applications in Financial Econometrics)
  • Article
  • Open Access
2 Citations
670 Views
20 Pages

6 December 2025

Pavement cracks are a critical indicator for assessing structural health and forecasting deterioration trends. Accurate and automated crack classification is of paramount importance for the intelligent maintenance of road structures. Inspired by the...

(This article belongs to the Section F: Engineering and Materials)
  • Article
  • Open Access
1,624 Views
20 Pages

28 September 2025

Object detection in soccer scenes serves as a fundamental task for soccer video analysis and target tracking. This paper proposes WCC-YOLO, a symmetry-enhanced object detection framework based on YOLOv11n. Our approach integrates symmetry principles...

(This article belongs to the Section A: Computer Science)
  • Article
  • Open Access
41 Citations
4,924 Views
19 Pages

Transmission Line Defect Detection Algorithm Based on Improved YOLOv12

  • Yanpeng Ji,
  • Tianxiang Ma,
  • Hongliang Shen,
  • Haiyan Feng and ,
  • Zizi Zhang,
  • Dan Li and
  • Yuling He
  • + 2 authors+ 0 author

To address the challenges of high missed detection rates for minute transmission line defects, strong complex background interference, and limited computational power on edge devices in UAV-assisted power line inspection, this paper proposes a lightw...

(This article belongs to the Section Artificial Intelligence)
  • Article
  • Open Access
1 Citations
2,077 Views
13 Pages

18 May 2023

Multivariate analysis can be used to study industrial process data exhibiting collinearity between variables. Such data can often be collected into conceptually meaningful groups or blocks. While data blocks may appear intuitive (e.g., raw material p...

(This article belongs to the Section AI-Enabled Process Engineering)
  • Article
  • Open Access
5 Citations
3,428 Views
18 Pages

Poplar wood is the main source of renewable biomass energy worldwide, and is also considered to be a model system for studying woody plants. The Full-length cDNA Over-eXpressing (FOX) gene hunting system is an effective method for generating gain-of-...

(This article belongs to the Section Molecular Plant Sciences)
  • Article
  • Open Access
4 Citations
3,176 Views
14 Pages

The Synthesis and Pharmacokinetics of a Novel Liver-Targeting Cholic Acid-Conjugated Carboplatin in Rats

  • Yinyin Lan,
  • Fuguo Han,
  • Anli Gao,
  • Xuemei Fan and ,
  • Yanli Hao,
  • Zhao Wang,
  • Weiping Liu,
  • Jing Jiang and
  • Qingfei Liu
  • + 4 authors+ 0 author

A novel cholic acid-conjugated carboplatin (CP-CA) is developed as a liver-targeting prodrug of carboplatin (CP) for liver cancer. Instead of using CP as a raw material, CP-CA was synthesized simultaneously. This paper is focused on the comparison of...

(This article belongs to the Section Bioinorganic Chemistry)
  • Article
  • Open Access
2 Citations
2,701 Views
23 Pages

Effect of Acetylsalicylic Acid on Biological Properties of Novel Cement Based on Calcium Phosphate Doped with Ions of Strontium, Copper, and Zinc

  • Tamara Vlajić Tovilović,
  • Sanja Petrović,
  • Miloš Lazarević,
  • Aleksandar Pavić and ,
  • Nikola Plačkić,
  • Aleksa Milovanović,
  • Miloš Milošević,
  • Vesna Miletic,
  • Djordje Veljović and
  • Milena Radunović
  • + 5 authors+ 0 author

This study aimed to compare the biological properties of newly synthesized cements based on calcium phosphate with a commercially used cement, mineral trioxide aggregate (MTA). Strontium (Sr)-, Copper (Cu)-, and Zinc (Zn)-doped hydroxyapatite (miHAp)...

(This article belongs to the Special Issue Molecular Research of Biofilms in Microbial Infections)
  • Article
  • Open Access
17 Citations
2,348 Views
13 Pages

Preparation, Characterization and Stability of Calcium-Binding Peptides Derived from Chicken Blood

  • Jing Yang,
  • Jing Shi,
  • Ying Zhou,
  • Ye Zou and ,
  • Weimin Xu,
  • Xiudong Xia and
  • Daoying Wang
  • + 2 authors+ 0 author

26 July 2024

Calcium-binding peptides have gained significant attention due to their potential applications in various fields. In this study, we aimed to prepare, characterize, and evaluate the stability of calcium-binding peptides derived from chicken blood. Chi...

(This article belongs to the Special Issue Advances in Sources, Extraction, Encapsulation, Bioavailability and Health Benefits of Functional Food Ingredients)
  • Article
  • Open Access
33 Citations
6,831 Views
14 Pages

The increasing demand for low-viscosity engine oil has underscored the role of zinc dialkyldithiophosphates (ZDDP) as a conventional anti-wear and antioxidant additive. It is essential to investigate the influence of modern additives such as cyclopro...

  • Article
  • Open Access
6 Citations
4,043 Views
15 Pages

The Metabolic Regulation of Amino Acid Synthesis Counteracts Reactive Nitrogen Stress via Aspergillus nidulans Cross-Pathway Control

  • Madoka Amahisa,
  • Madoka Tsukagoshi,
  • Chihiro Kadooka,
  • Shunsuke Masuo and ,
  • Norio Takeshita,
  • Yuki Doi,
  • Hiroshi Takagi and
  • Naoki Takaya
  • + 3 authors+ 0 author

10 January 2024

Nitric oxide (NO) is a natural reactive nitrogen species (RNS) that alters proteins, DNA, and lipids and damages biological activities. Although microorganisms respond to and detoxify NO, the regulation of the cellular metabolic mechanisms that cause...

(This article belongs to the Section Fungal Cell Biology, Metabolism and Physiology)
  • Article
  • Open Access
8 Citations
4,520 Views
12 Pages

Enhanced Phycocyanobilin Production in Escherichia coli by Fusion-Expression of Apo-Proteins with Signal Peptides

  • Xiaolin Liu,
  • Jing Yu,
  • Qian Che,
  • Tianjiao Zhu and ,
  • Dehai Li and
  • Guojian Zhang
  • + 1 author+ 0 author

Phycocyanobilin (PCB) is the bioactive chromophore attached to Phycocyanin (PC) that is of special interest for nutraceutical and therapeutic applications. However, the production of PCB from the heterologous host Escherichia coli is still very low....

(This article belongs to the Special Issue Production of Nutritional and Functional Properties in Genetically Engineered Microorganisms)
  • Article
  • Open Access
4 Citations
1,527 Views
16 Pages

22 August 2025

Lanthanide hydrogen-bonded organic frameworks (Ln-HOFs) integrating luminescent and proton-conductive properties hold significant promise for multifunctional sensing and energy applications, yet their development remains challenging due to the diffic...

(This article belongs to the Section Molecular Structure)
  • Article
  • Open Access
5 Citations
4,783 Views
22 Pages

Urinary Metabolite Profiling to Non-Invasively Monitor the Omega-3 Index: An Exploratory Secondary Analysis of a Randomized Clinical Trial in Young Adults

  • Brittany C. MacIntyre,
  • Meera Shanmuganathan,
  • Shannon L. Klingel,
  • Zachary Kroezen and ,
  • Erick Helmeczi,
  • Na-Yung Seoh,
  • Vanessa Martinez,
  • Adrian Chabowski,
  • Zeny Feng and
  • David M. Mutch
  • + 6 authors+ 1 author

12 October 2023

The Omega-3 Index (O3I) reflects eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) content in erythrocytes. While the O3I is associated with numerous health outcomes, its widespread use is limited. We investigated whether urinary metabolites...

(This article belongs to the Section Advances in Metabolomics)
  • Article
  • Open Access
1 Citations
530 Views
24 Pages

Accurate footprint image segmentation is challenging in forensic applications because fine anatomical structures, weak boundaries, and background interference can degrade segmentation performance. This study presents a task-oriented generative advers...

(This article belongs to the Special Issue Deep Learning in Image Processing and Pattern Recognition, 2nd Edition)
  • Article
  • Open Access
35 Citations
7,952 Views
18 Pages

Experimental Methodologies and Evaluations of Computer-Aided Drug Design Methodologies Applied to a Series of 2-Aminothiophene Derivatives with Antifungal Activities

  • Luciana Scotti,
  • Marcus Tullius Scotti,
  • Edeltrudes De Oliveira Lima,
  • Marcelo Sobral da Silva and ,
  • Maria Do Carmo Alves de Lima,
  • Ivan Da Rocha Pitta,
  • Ricardo Olímpio de Moura,
  • Jaismary Gonzaga Batista de Oliveira,
  • Rayssa Marques Duarte da Cruz and
  • Francisco Jaime Bezerra Mendonça
  • + 5 authors+ 0 author

24 February 2012

Fifty 2-[(arylidene)amino]-4,5-cycloalkyl[b]thiophene-3-carbonitrile derivatives were screened for their in vitro antifungal activities against Candida krusei and Cryptococcus neoformans. Based on experimentally determined minimum inhibitory concentr...

  • Article
  • Open Access
12 Citations
5,685 Views
14 Pages

10 March 2020

Sol-gel spread self-combustion is the burning of the complexing agent in dried gel and the oxidant. Meanwhile, high temperature takes place during the combustion process, which is harmful to the pore structure of the catalyst. The nitrate from metal...

  • Article
  • Open Access
1,000 Views
11 Pages

Fetuin-A Can Assess the Severity of Alcohol-Related Liver Disease

  • Musa Salmanoğlu,
  • İrfan Küçük and
  • Süleyman Baş

25 June 2025

Background and Objectives: Fetuin-A is mostly synthesized in the liver. It is a hepatokine, which is an extracellular inhibitor of growth factors. There is a scarcity of data on the clinical utility of serum fetuin-A (SFA) in alcohol-associated cirrh...

(This article belongs to the Section Gastroenterology & Hepatology)
  • Article
  • Open Access
9 Citations
4,635 Views
18 Pages

11 January 2022

Hyperspectral imaging has increasingly been used in high-throughput plant phenotyping systems. Rapid advancement in the field of phenotyping has resulted in a wide array of hyperspectral imaging systems. However, sharing the plant feature prediction...

  • Article
  • Open Access
8 Citations
4,453 Views
19 Pages

Complex Principal Component Analysis of Antarctic Ice Sheet Mass Balance

  • Jingang Zhan,
  • Hongling Shi,
  • Yong Wang and
  • Yixin Yao

29 January 2021

Ice sheet changes of the Antarctic are the result of interactions among the ocean, atmosphere, and ice sheet. Studying the ice sheet mass variations helps us to understand the possible reasons for these changes. We used 164 months of Gravity Recovery...

  • Article
  • Open Access
42 Citations
12,530 Views
15 Pages

Chemometric Studies on Natural Products as Potential Inhibitors of the NADH Oxidase from Trypanosoma cruzi Using the VolSurf Approach

  • Luciana Scotti,
  • Elizabeth Igne Ferreira,
  • Marcelo Sobral da Silva and
  • Marcus Tullius Scotti

21 October 2010

Natural products have widespread biological activities, including inhibition of mitochondrial enzyme systems. Some of these activities, for example cytotoxicity, may be the result of alteration of cellular bioenergetics. Based on previous computer-ai...

(This article belongs to the Special Issue Phenolics and Polyphenolics)
  • Article
  • Open Access
19 Citations
4,679 Views
14 Pages

20 January 2019

In this study, the setting property and mechanical strength of cement pastes containing accelerators (CPCA) with or without superabsorbent polymers (SAPs) were first studied. The early microstructure evolution and water distribution at 7 and 28 days...

(This article belongs to the Section Advanced Materials Characterization)
  • Article
  • Open Access
311 Views
25 Pages

17 September 2026

To address the challenges of limited visual information of PPE and complex background interference that constrains detection performance in substation operation scenarios, an efficient detection model, SDC-YOLOv10n, is proposed based on YOLOv10n. The...

  • Article
  • Open Access
2 Citations
3,965 Views
15 Pages

Application of Unsupervised Multivariate Analysis Methods to Raman Spectroscopic Assessment of Human Dental Enamel

  • Iulian Otel,
  • Joao Silveira,
  • Valentina Vassilenko,
  • António Mata and ,
  • Maria Luísa Carvalho,
  • José Paulo Santos and
  • Sofia Pessanha
  • + 2 authors+ 0 author

28 December 2021

This work explores the suitability of data treatment methodologies for Raman spectra of teeth using multivariate analysis methods. Raman spectra were measured in our laboratory and obtained from control enamel samples and samples with a protective tr...

(This article belongs to the Special Issue Computing, Electrical and Industrial Systems 2021)
  • Article
  • Open Access
6 Citations
2,460 Views
25 Pages

MFCA-Transformer: Modulation Signal Recognition Based on Multidimensional Feature Fusion

  • Xiao Hu,
  • Mingju Chen,
  • Xingyue Zhang,
  • Jie Rao and ,
  • Senyuan Li and
  • Xiaofei Song
  • + 1 author+ 0 author

14 August 2025

In order to solve the problems of modulation signals in low signal-to-noise ratio (SNR), such as poor feature extraction ability, strong dependence on single modal data, and insufficient recognition accuracy, this paper proposes a multi-dimensional f...

(This article belongs to the Special Issue Sensors Technologies for Measurements and Signal Processing)
  • Article
  • Open Access
40 Citations
6,854 Views
13 Pages

Characterization of ACE Inhibitory Peptides Prepared from Pyropia pseudolinearis Protein

  • Yuya Kumagai,
  • Keigo Toji,
  • Satoshi Katsukura,
  • Rie Morikawa and ,
  • Toshiki Uji,
  • Hajime Yasui,
  • Takeshi Shimizu and
  • Hideki Kishimura
  • + 3 authors+ 0 author

1 April 2021

More than 7000 red algae species have been classified. Although most of them are underused, they are a protein-rich marine resource. The hydrolysates of red algal proteins are good candidates for the inhibition of the angiotensin-I-converting enzyme...

(This article belongs to the Special Issue Bioactive Peptides from Marine By-Products and Underused Marine Organisms)
  • Article
  • Open Access
1 Citations
1,585 Views
22 Pages

Cgc-YOLO: A New Detection Model for Defect Detection of Tea Tree Seeds

  • Yuwen Liu,
  • Hao Li,
  • Kefan Yu,
  • Hui Zhu and ,
  • Binjie Zhang,
  • Wangyu Wu and
  • Hongbo Mu
  • + 2 authors+ 0 author

2 September 2025

Tea tree seeds are highly sensitive to dehydration and cannot be stored for extended periods, making surface defect detection crucial for preserving their germination rate and overall quality. To address this challenge, we propose Cgc-YOLO, an enhanc...

(This article belongs to the Section Sensing and Imaging)
  • Article
  • Open Access
24 Citations
8,634 Views
11 Pages

Expression of the Y-Encoded TSPY is Associated with Progression of Prostate Cancer

  • Tatsuo Kido,
  • Shingo Hatakeyama,
  • Chikara Ohyama and
  • Yun-Fai Chris Lau

14 September 2010

TSPY is a Y-encoded gene that is expressed in normal testicular germ cells and various cancer types including germ cell tumor, melanoma, hepatocellular carcinoma, and prostate cancer. Currently, the correlation between TSPY expression and oncogenic d...

(This article belongs to the Special Issue The TSPY Gene Family)
  • Article
  • Open Access
9 Citations
7,140 Views
17 Pages

The Benefits of an Integral HAMMAM Experience Combining Hydrotherapy and Swedish Massage on Pain, Subjective Well-Being and Quality of Life in Women with Endometriosis-Related Chronic Pelvic Pain: A Randomized Controlled Trial

  • Ángel Rodríguez-Ruiz,
  • Camila Arcos-Azubel,
  • Manuel Ruiz-Pérez,
  • Francisco Manuel Peinado and ,
  • Antonio Mundo-López,
  • Ana Lara-Ramos,
  • María del Mar Salinas-Asensio and
  • Francisco Artacho-Cordón
  • + 3 authors+ 0 author

13 October 2024

Background and Objectives: To evaluate the effectiveness of an integral HAMMAM experience, a 4-week therapeutic program that combined hydrotherapy and Swedish massage, applied in a multisensorial immersive environment, on pain, well-being and quality...

(This article belongs to the Special Issue Diagnosis and Treatment of Endometriosis: Priorities, Advances and Challenges)
  • Article
  • Open Access
2 Citations
2,179 Views
19 Pages

YOLOv11-GLIDE: An Improved YOLOv11n Student Behavior Detection Algorithm Based on Scale-Based Dynamic Loss and Channel Prior Convolutional Attention

  • Haiyan Wang,
  • Guiyuan Gao,
  • Wei Zhang,
  • Kejing Li and ,
  • Na Che,
  • Caihua Yan and
  • Liu Wang
  • + 2 authors+ 0 author

14 November 2025

Student classroom behavior recognition is a core research direction in intelligent education systems. Real-time analysis of students’ learning states and behavioral features through classroom monitoring provides quantitative support for teachin...

(This article belongs to the Special Issue AI-Based Computer Vision Sensors & Systems—2nd Edition)
  • Article
  • Open Access
5 Citations
2,161 Views
19 Pages

17 June 2025

Excessive bait wastage is a major issue in aquaculture, leading to higher farming costs, economic losses, and water pollution caused by bacterial growth from unremoved residual bait. To address this problem, we propose a bait residue detection and co...

(This article belongs to the Topic The Importance of Fish Phenotype in Aquaculture, Fisheries and Conservation)
  • Article
  • Open Access
38 Citations
5,833 Views
15 Pages

Contribution of Chronic Fatigue to Psychosocial Status and Quality of Life in Spanish Women Diagnosed with Endometriosis

  • Antonio Mundo-López,
  • Olga Ocón-Hernández,
  • Ainhoa P. San-Sebastián,
  • Noelia Galiano-Castillo and ,
  • Olga Rodríguez-Pérez,
  • María S. Arroyo-Luque,
  • Manuel Arroyo-Morales,
  • Irene Cantarero-Villanueva,
  • Carolina Fernández-Lao and
  • Francisco Artacho-Cordón
  • + 5 authors+ 0 author

Aim: To analyze the levels of chronic fatigue in Spanish women with endometriosis and its relationship with their psychosocial status and quality of life (QoL). Methods: A total of 230 Spanish women with a clinical diagnosis of endometriosis were rec...

(This article belongs to the Special Issue Policies and Strategies in Sexual and Reproductive Health)
  • Article
  • Open Access
2 Citations
911 Views
18 Pages

4 December 2025

Steel surface defect detection is critical for ensuring industrial product quality and safety. Although deep learning-based detectors like the YOLO series have demonstrated considerable promise, they often struggle with three key challenges under com...

(This article belongs to the Section F: Engineering and Materials)
  • Article
  • Open Access
523 Views
32 Pages

Soybean Field Weed Segmentation and Prescription Map Generation Based on SCG-UNet Fusion of UAV RGB and Multispectral Images

  • He Li,
  • Qianyi Wang,
  • Zishang Yang,
  • Xiuyuan Zhang and ,
  • Qiming Ding and
  • Lele Wang
  • + 1 author+ 0 author

23 July 2026

Weed segmentation in soybean fields is essential to improving herbicide use efficiency and supporting precision variable-rate spraying. This study developed an SiLU–CPCA–Gate U-Net (SCG-UNet) using fused UAV RGB and multispectral imagery...

(This article belongs to the Special Issue Advances in Precision Agricultural Aviation)
  • Article
  • Open Access
311 Views
20 Pages

Road Rockfall Detection by Integrating Feature Engineering with YOLO and Cascade Decision Fusion

  • Zhiqing Qin,
  • Tao Niu,
  • Caijin Lu,
  • Yongsheng Dai and ,
  • Xiantao Liu,
  • Peng Peng and
  • Jiachun Li
  • + 2 authors+ 0 author

16 September 2026

In roadside surveillance imagery, shadows, vegetation, vehicles, exposed pavement, and water stains may exhibit local textures and morphological characteristics similar to those of rockfalls, causing a standalone You Only Look Once (YOLO) real-time o...

(This article belongs to the Section Transportation and Future Mobility)
  • Article
  • Open Access
5 Citations
1,771 Views
28 Pages

20 January 2026

Printed circuit boards (PCBs) are critical in the electronics industry. As PCB layouts grow increasingly complex, defect detection processes often encounter challenges such as low image contrast, uneven brightness, minute defect sizes, and irregular...

(This article belongs to the Section Physical Sensors)
  • Study Protocol
  • Open Access
14 Citations
14,243 Views
16 Pages

‘Physio-EndEA’ Study: A Randomized, Parallel-Group Controlled Trial to Evaluate the Effect of a Supervised and Adapted Therapeutic Exercise Program to Improve Quality of Life in Symptomatic Women Diagnosed with Endometriosis

  • María del Mar Salinas-Asensio,
  • Olga Ocón-Hernández,
  • Antonio Mundo-López,
  • Carolina Fernández-Lao and ,
  • Francisco M. Peinado,
  • Carmen Padilla-Vinuesa,
  • Francisco Álvarez-Salvago,
  • Paula Postigo-Martín,
  • Mario Lozano-Lozano and
  • Francisco Artacho-Cordón
  • + 8 authors+ 3 authors

Aim: The ‘Physio-EndEA’ study aims to explore the potential benefits of a therapeutic exercise program (focused on lumbopelvic stabilization and tolerance to exertion) on the health-related quality of life (HRQoL) of symptomatic endometri...

(This article belongs to the Special Issue Musculoskeletal Disorders, Physical Rehabilitation and Health)
  • Article
  • Open Access
1 Citations
1,093 Views
11 Pages

Cost Analysis of PSMA-PET in the PROSPET-BX Trial

  • Egesta Lopci,
  • Cesare Saitta,
  • Alberto Saita,
  • Elena Vanni and ,
  • Alessandro Santandrea,
  • Luca Disconzi,
  • Vittorio Fasulo,
  • Nicolò Buffi,
  • Massimo Lazzeri and
  • Giovanni Lughezzani
  • + 5 authors+ 0 author

2 March 2026

Background: The PROSPET-BX trial compared [68Ga]PSMA-11 PET/CT (PSMA-PET) with multiparametric MRI (mpMRI) in parallel in men with suspicion of prostate cancer (PCa) after at least one previously negative biopsy (ClinicalTrials.gov: NCT05297162; GR-2...

(This article belongs to the Special Issue Cancer Treatment: Present and Future of Radioligand Therapy)
  • Article
  • Open Access
37 Citations
9,220 Views
13 Pages

Chronic Fatigue, Physical Impairments and Quality of Life in Women with Endometriosis: A Case-Control Study

  • Francisco Álvarez-Salvago,
  • Ana Lara-Ramos,
  • Irene Cantarero-Villanueva,
  • Maryna Mazheika and ,
  • Antonio Mundo-López,
  • Noelia Galiano-Castillo,
  • Carolina Fernández-Lao,
  • Manuel Arroyo-Morales,
  • Olga Ocón-Hernández and
  • Francisco Artacho-Cordón
  • + 5 authors+ 0 author

Aim: To explore endometriosis-related fatigue (ERF), health-related fitness, sleep quality, and health-related quality of life (HRQoL) in women with endometriosis in comparison with matched controls. Methods: Twenty-five affected women and twenty-fiv...

(This article belongs to the Special Issue Global Women's Health)