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45 Results Found

  • Review
  • Open Access

11 November 2026

The development of complex and unconventional reservoirs places higher demands on enhanced oil recovery (EOR) technologies. To address issues such as insufficient control of gas flow rate and chemical agent loss, colloidal gas aphron (CGA) has attrac...

(This article belongs to the Special Issue Advanced Technologies for Efficient Oil and Gas Production and Recovery Enhancement)
  • Article
  • Open Access
3 Citations
1,314 Views
36 Pages

7 February 2026

Severe fluid loss in fractured, depleted reservoirs usually defeat conventional water-based drilling fluids (WBDFs), and rigid lost-circulation materials (LCMs) struggle to form durable, conformal seals. We report an eco-oriented colloidal gas aphron...

  • Article
  • Open Access
15 Citations
3,911 Views
11 Pages

Stability Study and Identification of Degradation Products of Caffeoylgluconic Acid Derivatives from Fructus Euodiae

  • Huijuan Yu,
  • Jing Yang,
  • Jiamin Ding,
  • Ying He and ,
  • Zhenzuo Jiang,
  • Xin Chai and
  • Yuefei Wang
  • + 2 authors+ 0 author

8 August 2018

Caffeoylgluconic acid derivatives are characteristic constituents isolated from the aqueous extract of Fructus Euodiae. In this research focusing on caffeoylgluconic acid derivatives, trans-caffeoyl-6-O-d-gluconic acid (CGA), trans-caffeoyl-6-O-d-glu...

  • Article
  • Open Access
3 Citations
1,615 Views
17 Pages

pH-Responsive Sodium Alginate/Carboxymethyl Cellulose Hydrogels for Enhanced Stability and Gastrointestinal Sustained Release Delivery of Chlorogenic Acid

  • Lanxin Ke,
  • Linqing Qian,
  • Yincong Chen,
  • Yanchen Ren and ,
  • Meiqi Shi,
  • Kun Wang and
  • Ting Wang
  • + 2 authors+ 0 author

29 April 2026

Chlorogenic acid (CGA) is a natural polyphenol with various biological activities, but its poor stability and premature release in the gastrointestinal tract limit oral application. Herein, a pH-responsive bilayer hydrogel based on sodium alginate (S...

(This article belongs to the Special Issue Smart Polymeric Materials for Biomedical Applications)
  • Review
  • Open Access
43 Citations
9,532 Views
13 Pages

22 October 2020

Cyclic GMP–AMP synthase (cGAS) is the synthase that generates the second messenger cyclic GMP–AMP (cGAMP) upon DNA binding. cGAS was first discovered as the cytosolic DNA sensor that detects DNA exposed in the cytoplasm either from pathog...

(This article belongs to the Special Issue DNA or RNA-Mediated Innate Immune Response)
  • Article
  • Open Access
5 Citations
3,949 Views
17 Pages

A Hierarchical Porous Cellulose Sponge Modified with Chlorogenic Acid as a Antibacterial Material for Water Disinfection

  • En-Jiang Liu,
  • Jia-Xing Huang,
  • Run-Ze Hu,
  • Xiao-Hui Yao and ,
  • Wei-Guo Zhao,
  • Dong-Yang Zhang and
  • Tao Chen
  • + 2 authors+ 0 author

31 December 2022

Water contaminated by microorganisms will seriously endanger public safety, as many diseases are caused by microorganisms, and water disinfection materials offer an effective method to solve this problem. In this work, a hierarchical porous structure...

(This article belongs to the Special Issue Recent Advances in Biomass Conversion, Renewable Energy, and Biomaterials)
  • Article
  • Open Access
12 Citations
5,498 Views
15 Pages

Experimental Investigation of Water Based Colloidal Gas Aphron Fluid Stability

  • Seyed Arman Hosseini-Kaldozakh,
  • Ehsan Khamehchi,
  • Bahram Dabir,
  • Ali Alizadeh and
  • Zohreh Mansoori

Today, the drilling operators use the Colloidal Gas Aphron (CGA) fluids as a part of drilling fluids in their operations to reduce formation damages in low-pressure, mature or depleted reservoirs. In this paper, a Taguchi design of experiment (DOE) h...

  • Article
  • Open Access
1,352 Views
17 Pages

Chlorogenic Acid Alleviates Chronic Stress-Induced Ileal Oxidative Stress and Apoptosis in Rats by Influencing Intestinal Flora and Activating Nrf2 Pathway

  • Wenjing Jiao,
  • Haoyang Tan,
  • Xin Cheng,
  • Tianyuan Yang and ,
  • Xuanpan Ding,
  • Yaxin Ji,
  • Haotian Yang,
  • Jichen Sha,
  • Guofeng Feng and
  • Honggang Fan
  • + 6 authors+ 1 author

24 October 2025

Background: Chronic stress is implicated in the pathogenesis of gastrointestinal disorders, with reactive oxygen species (ROS) contributing significantly. Chlorogenic acid (CGA), a polyphenolic compound, exhibits antioxidant properties. This study in...

(This article belongs to the Section Microbiology)
  • Article
  • Open Access
18 Citations
4,128 Views
29 Pages

Preparation and Properties of Composite Graphene/Carbon Fiber Pouring Conductive Asphalt Concrete

  • Zhenxia Li,
  • Tengteng Guo,
  • Yuanzhao Chen,
  • Yibin Wang and ,
  • Xiangjie Niu,
  • Deqing Tang,
  • Menghui Hao,
  • Xu Zhao and
  • Jinyuan Liu
  • + 4 authors+ 0 author

13 April 2023

To solve the problem of snow on steel bridge areas endangering traffic safety and low road traffic efficiency in winter, conductive gussasphait concrete (CGA) was prepared by mixing conductive phase materials (graphene and carbon fiber) into Gussasph...

(This article belongs to the Special Issue Recent Developments in Geopolymer Composites)
  • Article
  • Open Access
6 Citations
1,787 Views
21 Pages

Spray-Dried Multiple Emulsions as Co-Delivery Systems for Chlorogenic Acid and Curcumin

  • Javier Paredes-Toledo,
  • Javier Herrera,
  • Estefanía González,
  • Paz Robert and
  • Begoña Giménez

20 October 2025

The low stability and bioaccessibility of polyphenols limit their application in functional foods. To address this, chlorogenic acid (CGA) and curcumin (CU) were selected as model compounds and co-encapsulated in spray-dried linseed oil (LO) multiple...

(This article belongs to the Special Issue Innovations in Drug Delivery Systems for Antioxidant-Based Therapeutic Agents)
  • Article
  • Open Access
32 Citations
3,994 Views
21 Pages

Preparation and Characterization of Phenolic Acid-Chitosan Derivatives as an Edible Coating for Enhanced Preservation of Saimaiti Apricots

  • Fangjie Li,
  • Yingying Yan,
  • Chengzhi Gu,
  • Jiaying Sun and ,
  • Yaru Han,
  • Zhaoqing Huangfu,
  • Fangyuan Song and
  • Jiluan Chen
  • + 3 authors+ 0 author

8 November 2022

In this study, caffeic acid (CA) and chlorogenic acid (CGA) were incorporated onto chitosan (CS) using free radical grafting initiated by a hydrogen peroxide/ascorbic acid (H2O2/Vc) redox system. The structural properties of the CA (CA-g-CS) and CGA...

(This article belongs to the Section Food Packaging and Preservation)
  • Review
  • Open Access
163 Citations
15,658 Views
23 Pages

Coffee Chlorogenic Acids Incorporation for Bioactivity Enhancement of Foods: A Review

  • Alexis Rojas-González,
  • Claudia Yuritzi Figueroa-Hernández,
  • Oscar González-Rios,
  • Mirna Leonor Suárez-Quiroz and ,
  • Rosa María González-Amaro,
  • Zorba Josué Hernández-Estrada and
  • Patricia Rayas-Duarte
  • + 2 authors+ 0 author

The demand of foods with high antioxidant capacity have increased and research on these foods continues to grow. This review is focused on chlorogenic acids (CGAs) from green coffee, which is the most abundant source. The main CGA in coffee is 5-O-ca...

(This article belongs to the Special Issue Chemistry of Tea and Coffee)
  • Article
  • Open Access
36 Citations
6,506 Views
16 Pages

EZH2–CCF–cGAS Axis Promotes Breast Cancer Metastasis

  • Dandan Duan,
  • Mengjie Shang,
  • Yanxu Han,
  • Jiayuan Liu and ,
  • Jiwei Liu,
  • Sun Hyok Kong,
  • Jingyao Hou,
  • Baiqu Huang,
  • Jun Lu and
  • Yu Zhang
  • + 5 authors+ 0 author

4 February 2022

Cytoplasmic chromatin fragments (CCF) are recognized by the cytoplasmic DNA sensor cyclic GMP-AMP synthase (cGAS), which activates the cGAS–STING (cyclic GMP-AMP synthase-stimulator of interferon genes) pathway and promotes the production of in...

(This article belongs to the Special Issue From Omics to Therapeutic Targets in Cancer)
  • Article
  • Open Access
18 Citations
7,065 Views
9 Pages

Salt Effects on Formation and Stability of Colloidal Gas Aphrons Produced by Anionic and Zwitterionic Surfactants in Xanthan Gum Solution

  • Behnam Keshavarzi,
  • Mohsen Mahmoudvand,
  • Aliyar Javadi,
  • Alireza Bahramian and ,
  • Reinhard Miller and
  • Kerstin Eckert
  • + 1 author+ 0 author

This work is devoted to the influence of NaCl salt concentration on the formation and stability of colloidal gas aphrons (CGA) produced by the anionic surfactant sodium dodecyl sulfate (SDS) and zwitterionic surfactant coco amido propyl betaine (CAPB...

(This article belongs to the Special Issue Ion Specific Effects in Colloid and Surface Science – Where Biology, Chemistry and Physics Meet)
  • Communication
  • Open Access
5 Citations
4,382 Views
16 Pages

Inhibitory Effect of Chlorogenic Acid Analogues Comprising Pyridine and Pyrimidine on α-MSH-Stimulated Melanogenesis and Stability of Acyl Analogues in Methanol

  • Jaeuk Sim,
  • Srinu Lanka,
  • Jeong-Woong Jo,
  • Chhabi Lal Chaudhary and ,
  • Manjunatha Vishwanath,
  • Chan-Hyun Jung,
  • Young-Hee Lee,
  • Eun-Yeong Kim,
  • Young-Soo Kim and
  • Jae-Kyung Jung
  • + 10 authors+ 5 authors

17 November 2021

In continuation of studies for α-MSH stimulated melanogenesis inhibitors, we have evaluated the design, synthesis, and activity of a new series of chlorogenic acid (CGA) analogues comprising pyridine, pyrimidine, and diacyl derivatives. Among ninetee...

(This article belongs to the Section Medicinal Chemistry)
  • Review
  • Open Access
1 Citations
889 Views
47 Pages

Multifunctional Roles of Chlorogenic Acid in Food Packaging Films: Linking Structural Modulation with Active and Intelligent Performance

  • Hamid Rajabi,
  • Wanli Zhang,
  • Di Wu,
  • Pang Bo and ,
  • Young Hoon Jung and
  • Saroat Rawdkuen
  • + 1 author+ 0 author

8 May 2026

The transition toward sustainable food packaging requires the integration of biodegradable materials with functional bioactivity. Chlorogenic acid (CGA), a naturally abundant polyphenol, has emerged as a multifunctional compound with the capacity to...

(This article belongs to the Special Issue Discovery and Utilization of Food-Derived Bioactive Polymers: Focusing on Polypeptide, Polysaccharide, and Polyphenol)
  • Article
  • Open Access
46 Citations
6,230 Views
29 Pages

20 September 2019

Naturally existing Chlorogenic acid (CGA) is an antioxidant-rich compound reported to act a chemopreventive agent by scavenging free radicals and suppressing cancer-causing mechanisms. Conversely, the compound’s poor thermal and pH (neutral and basic...

(This article belongs to the Special Issue Chitosan Functionalizations, Formulations and Composites)
  • Article
  • Open Access
672 Views
29 Pages

21 August 2026

Breast cancer cells exhibit a reversed pH gradient and metabolic plasticity that promote proliferation, invasion, and resistance to therapy. Natural products such as chlorogenic acid (CGA) and cinnamaldehyde (CA) have shown emerging anticancer potent...

(This article belongs to the Special Issue Recent Advances in Development of Small Molecules to Fight Cancer—3rd Edition)
  • Article
  • Open Access
21 Citations
3,607 Views
15 Pages

5 November 2022

Hepatotoxicity brought on by acetaminophen (APAP) is significantly impacted by mitochondrial dysfunction. Mitophagy, particularly PINK1-mediated mitophagy, maintains the stability of cell function by eliminating damaged mitochondria. One of the most...

(This article belongs to the Section Novel Methods in Toxicology Research)
  • Article
  • Open Access
16 Citations
2,719 Views
23 Pages

6 February 2023

Short-term power load forecasting is critical for ensuring power system stability. A new algorithm that combines CNN, GRU, and an attention mechanism with the Sparrow algorithm to optimize variational mode decomposition (PSVMD–CGA) is proposed...

  • Article
  • Open Access
8 Citations
2,389 Views
19 Pages

Prospect of Gum Arabic–Cocoliposome Matrix to Encapsulate Curcumin for Oral Administration

  • Dwi Hudiyanti,
  • Muhammad Fuad Al Khafiz,
  • Khairul Anam,
  • Parsaoran Siahaan and ,
  • Linda Suyati,
  • Sunarsih Sunarsih and
  • Sherllyn Meida Christa
  • + 2 authors+ 0 author

29 March 2024

Curcumin is an antioxidant that can effectively eliminate free radicals. However, as its oral bioavailability is low, an effective delivery method is required. Phospholipid-based liposomes can encapsulate lipophilic drugs, such as curcumin, while lip...

(This article belongs to the Section Biobased and Biodegradable Polymers)
  • Article
  • Open Access
2 Citations
965 Views
28 Pages

The Double Life of Plant-Based Food Waste: A Source of Phenolic Acids and a Carrier for Immobilization of Lipases Capable of Their Lipophilization

  • Karina Jasińska,
  • Bartłomiej Zieniuk,
  • Marcin Bryła,
  • Daria Padewska and ,
  • Rita Brzezińska,
  • Bartosz Kruszewski,
  • Dorota Nowak and
  • Agata Fabiszewska
  • + 3 authors+ 0 author

25 November 2025

Addressing global food waste challenges, this study investigated plant-based byproducts, spent coffee grounds, apple, and chokeberry pomaces, as sources of phenolic acids and biodegradable carriers for lipase immobilization. The goal was to enhance t...

(This article belongs to the Section Bioactives and Nutraceuticals)
  • Article
  • Open Access
134 Views
25 Pages

Palmitoyl Pentapeptide-4-Functionalized Ethosomes with Surfactant-Tailored Bilayers for Enhanced Dermal Delivery of Chlorogenic Acid

  • Xiaoyi Huang,
  • Yafeng Liu,
  • Xiaoying Qiu,
  • Ran Lv and ,
  • Jingwen Zhang,
  • Mengjie Deng,
  • Yuchuan Qi,
  • Zhihua Liu and
  • Jiazhi Chen
  • + 4 authors+ 0 author

Background/Objectives: Chlorogenic acid (CGA), a potent antioxidant polyphenol, scavenges reactive oxygen species (ROS) and ameliorates oxidative stress-induced dermal extracellular matrix deterioration. However, its high hydrophilicity causes poor s...

(This article belongs to the Special Issue Biomimetic Drug Delivery Systems for Disease Treatment)
  • Article
  • Open Access
653 Views
19 Pages

19 March 2026

Operating data from tunnel boring machines (TBMs) capture the state of both the machine and the ground, and accurate forecasting of their evolving operating variables is essential for assessing rock-mass stability and improving construction efficienc...

(This article belongs to the Special Issue Advances in Tunnel Excavation and Underground Construction)
  • Article
  • Open Access
1 Citations
1,685 Views
19 Pages

Efficient operation of electric vehicle (EV) charging stations is vital in the development of green transportation infrastructure. To address the challenge of balancing profitability, resource utilization, user behavior, and grid stability, this pape...

(This article belongs to the Section Charging Infrastructure and Grid Integration)
  • Article
  • Open Access
1 Citations
2,218 Views
22 Pages

9 January 2026

Mugwort (Artemisia princeps Pamp.) is a traditional herb widely used across East Asia; despite this, optimal processing methods to preserve its functional components and palatability have not been fully established. Thus, we aimed to, for the first t...

(This article belongs to the Section Food Process Engineering)
  • Article
  • Open Access
18 Citations
5,201 Views
12 Pages

Pharmacogenetic Interventions Improve the Clinical Outcome of Treatment-Resistant Autistic Spectrum Disorder Sufferers

  • Maria J. Arranz,
  • Juliana Salazar,
  • Valentin Bote,
  • Alicia Artigas-Baleri and ,
  • Alexandre Serra-LLovich,
  • Emma Triviño,
  • Jordi Roige,
  • Carlos Lombardia,
  • Martha Cancino and
  • Amaia Hervas
  • + 9 authors+ 4 authors

BACKGROUND: Autistic spectrum disorders (ASD) are severe neurodevelopmental alterations characterised by deficits in social communication and repetitive and restricted behaviours. About a third of patients receive pharmacological treatment for comorb...

(This article belongs to the Special Issue Association Studies in Clinical Pharmacogenetics)
  • Article
  • Open Access
622 Views
28 Pages

Phenolic Copigment Enhanced Anthocyanin Stability and Color Intensity of Frozen Red Huajiao (Zanthoxylum bungeanum Maxim.) Fruit

  • Xin Yang,
  • Yishan Chen,
  • Xiao He,
  • Jiani Liu and ,
  • Shuang Xian,
  • Shanshan Li,
  • Xiaoyan Hou,
  • Man Zhou,
  • Qiang Cui and
  • Guanghui Shen
  • + 9 authors+ 4 authors

13 May 2026

Anthocyanin stability substantially determines the postharvest storage quality of red Huajiao (Zanthoxylum bungeanum Maxim.). Herein, the composition of red Huajiao anthocyanins (RHAs) was characterized, and the copigmentation performance of seven ph...

(This article belongs to the Special Issue Postharvest Technologies for Fresh Fruit and Vegetable: Developments for Loss Reduction During Handling and Storage—2nd Edition)
  • Article
  • Open Access
2 Citations
1,581 Views
13 Pages

Molecular Fractionation Induced by Viscosity-Driven Segregative Phase Separation Behavior of Gum Arabic/Hydroxypropyl Methylcellulose

  • Lingyu Han,
  • Cunzhi Zhang,
  • Nuo Dong,
  • Jixin Yang and ,
  • Qiuyue Zheng,
  • Xiaobo Zhang,
  • Ronggang Liu,
  • Jijuan Cao and
  • Bing Hu
  • + 4 authors+ 0 author

28 July 2025

Segregative phase separation technology demonstrates substantial potential for precise molecular fractionation in food and biomaterial applications. The investigation elucidates the causal relationship between viscosity variations and phase separatio...

(This article belongs to the Section Food Physics and (Bio)Chemistry)
  • Article
  • Open Access
4 Citations
1,839 Views
20 Pages

8 January 2026

To reduce the environmental impact of plastic packaging in the edible fungi supply chain, this study developed an edible natural chitosan composite film loaded with chlorogenic acid–chitosan oligosaccharide nanoparticles (CGA/COS NPs). The effe...

(This article belongs to the Section Food Packaging and Preservation)
  • Feature Paper
  • Article
  • Open Access
482 Views
16 Pages

Clinical Trajectories Associated with Pharmacological Treatment Patterns in Female Adolescents with Anorexia Nervosa: A 12-Month Retrospective Study in Italian Real-World Clinical Practice

  • Pamela Fantozzi,
  • Beatrice Fossati,
  • Fabio Apicella,
  • Vittorio Belmonti and ,
  • Francesca Ditaranto,
  • Raffaella Tancredi,
  • Pietro Muratori,
  • Valentina Levantini and
  • Sara Calderoni
  • + 4 authors+ 0 author

18 July 2026

Background: Pharmacological treatments are frequently prescribed for adolescents with anorexia nervosa (AN), mainly to address psychiatry comorbidities and associated clinical features, although evidence supporting medication-specific effects remains...

(This article belongs to the Section Mental Health)
  • Article
  • Open Access
34 Citations
4,931 Views
30 Pages

Tomato cultivation is a vital agricultural practice worldwide, yet it faces significant challenges due to various diseases that adversely affect crop yield and quality. This paper presents a novel tomato disease detection system within an operational...

(This article belongs to the Special Issue Artificial Intelligence and Pattern Recognition for Intelligent Systems)
  • Article
  • Open Access
43 Citations
6,085 Views
13 Pages

16 October 2020

The food industry is looking for alternatives to synthetic colorants. Anthocyanins (ACNs) are suitable replacements due to their color characteristics and potential health benefits. The application of sauco (Sambucus peruviana, SP) as a potential sou...

(This article belongs to the Special Issue Chemical Characterization and Evaluation of Natural Pigments as Food Colorants)
  • Article
  • Open Access
33 Citations
5,498 Views
15 Pages

Molecularly Imprinted Polymer Functionalized Bi2S3/Ti3C2TX MXene Nanocomposites for Photoelectrochemical/Electrochemical Dual-Mode Sensing of Chlorogenic Acid

  • Zhenli Qiu,
  • Dechun Fan,
  • Xianghang Xue,
  • Shujun Guo and ,
  • Youxiu Lin,
  • Yiting Chen and
  • Dianping Tang
  • + 2 authors+ 0 author

We report the proof-of-concept of molecularly imprinted polymer (MIP) functionalized Bi2S3/Ti3C2TX MXene nanocomposites for photoelectrochemical (PEC)/electrochemical (EC) dual-mode sensing of chlorogenic acid (CGA). Specifically, the in-situ growth...

(This article belongs to the Special Issue Photoelectrochemical (Bio)sensors for Biological, Food, and Environmental Analysis)
  • Article
  • Open Access
1 Citations
1,452 Views
19 Pages

Fate of Tebuconazole and Trifloxystrobin in Edible Rose Petals: Storage Stability and Human Health Risk Assessment

  • Xiaotong Qin,
  • Jinwei Zhang,
  • Yan Tao,
  • Li Chen and ,
  • Pingzhong Yu,
  • Junjie Jing,
  • Ercheng Zhao,
  • Yongquan Zheng and
  • Min He
  • + 4 authors+ 0 author

1 October 2025

This study addresses the absence of maximum residue limits (MRLs) for tebuconazole and trifloxystrobin in edible rose petals in China by systematically evaluating the residue behavior and dietary exposure risks of these fungicides. An analytical meth...

  • Article
  • Open Access
3 Citations
1,964 Views
18 Pages

Impact of Living Arrangements on Delirium in Older ED Patients

  • Andrea Russo,
  • Sara Salini,
  • Luigi Carbone,
  • Andrea Piccioni and ,
  • Francesco Pio Fontanella,
  • Fiorella Ambrosio,
  • Claudia Massaro,
  • Davide Della Polla,
  • Giuseppe De Matteis and
  • Marcello Covino
  • + 7 authors+ 2 authors

24 April 2025

Background: The purpose of this study is to assess how the socio–family demographic status of patients is related to the onset of delirium in a large cohort of older adults aged ≥65 years evaluated in the emergency department (ED) using a co...

(This article belongs to the Section Emergency Medicine)
  • Article
  • Open Access
19 Citations
4,320 Views
15 Pages

10 September 2021

Density functional theory (DFT) was used to study the structure, stability, and bonding in some selected neutral pentaatomic systems, viz., CGa2Ge2, CAlGaGe2, and CSiGa2Ge containing planar tetracoordinate carbon. The systems are kinetically stable,...

(This article belongs to the Special Issue Planar Tetracoordinate Carbon—Fifty Years and Beyond)
  • Review
  • Open Access
41 Citations
4,990 Views
21 Pages

Oral Pharmacokinetics of Hydroxycinnamic Acids: An Updated Review

  • Kleyton Santos Veras,
  • Flávia Nathiely Silveira Fachel,
  • Bibiana Verlindo de Araújo,
  • Helder Ferreira Teixeira and
  • Letícia Scherer Koester

Hydroxycinnamic acids (HCAs) such as caffeic acid (CA), chlorogenic acid (CGA), coumaric acid (COA) isomers, ferulic acid (FA) and rosmarinic acid (RA) are natural phenolic acids with widespread distribution in vegetal foods and well-documented pharm...

(This article belongs to the Special Issue Recent Advances in Natural Product Drugs)
  • Article
  • Open Access
8 Citations
3,687 Views
16 Pages

27 January 2022

Selecting effective antioxidants is challenging since their efficiency in inhibiting lipid oxidation depends on the rate constants of the chemical reactions involved and their concentration at the reaction site, i.e., at the interfacial region. Accum...

  • Review
  • Open Access
2 Citations
2,872 Views
33 Pages

RETRACTED: Endogenous Retroviruses as Regulators of Innate Immune Signaling and Inflammation

  • Muhammad Iftikhar,
  • Xinyan Wang,
  • Qiangzhou Wang,
  • Jiaxing Wang and ,
  • Lihong Gu and
  • Shihao Chen
  • + 1 author+ 0 author

27 February 2026

Endogenous retroviruses (ERVs) are remnants of ancient retroviral infections that were integrated into the human genome millions of years ago. They constitute approximately 8% of the human genome. Once considered “Junk DNA” it is now clear that ERVs...

(This article belongs to the Section General Virology)
  • Article
  • Open Access
537 Views
20 Pages

Enhanced YOLO11n for UAV-Based Surface Crack Detection in Mining Subsidence Areas

  • Mo Wang,
  • Nan Zhao,
  • Chuangchuang Liu,
  • Wanxiang Rao and
  • Zhijun Zhang

18 June 2026

Mining-subsidence-induced surface cracks pose substantial risks to ecological systems, infrastructure stability, and mining safety. Their thin, elongated, discontinuous, and low-contrast characteristics make accurate detection from unmanned aerial ve...

(This article belongs to the Special Issue Intelligent and Sustainable Safe Coal Mining: AI-Assisted Disaster Mitigation, Carbon Sequestration, and Energy Utilization)
  • Article
  • Open Access
2 Citations
661 Views
29 Pages

3 April 2026

Under maize–soybean rotation systems, weeds and crops at the seedling stage in dryland fields exhibit high similarity in morphological structure, scale distribution, and spatial arrangement. In addition, complex illumination conditions, occlusi...

(This article belongs to the Section Crop Physiology and Crop Production)
  • Article
  • Open Access
11 Citations
3,975 Views
18 Pages

Co-Encapsulation of Coffee and Coffee By-Product Extracts with Probiotic Kluyveromyces lactis

  • Dérica Gonçalves Tavares,
  • Mayara Andrade Martins de Souza,
  • Tamara Leite dos Santos,
  • Adriele do Amor Divino Silva and ,
  • Danilo José Machado de Abreu and
  • Whasley Ferreira Duarte
  • + 1 author+ 0 author

26 September 2024

Coffee and coffee by-products contain several chemical compounds of great relevance, such as chlorogenic acid (CGA), trigonelline, and caffeine. Furthermore, yeasts have been the target of studies for their use as probiotics because of their interest...

(This article belongs to the Special Issue Functionality and Stability of Probiotics, Postbiotics, and Parabiotics in the Food System)
  • Article
  • Open Access
43 Citations
5,723 Views
14 Pages

[68Ga]DOTATOC PET/CT Radiomics to Predict the Response in GEP-NETs Undergoing [177Lu]DOTATOC PRRT: The “Theragnomics” Concept

  • Riccardo Laudicella,
  • Albert Comelli,
  • Virginia Liberini,
  • Antonio Vento and ,
  • Alessandro Stefano,
  • Alessandro Spataro,
  • Ludovica Crocè,
  • Sara Baldari,
  • Michelangelo Bambaci and
  • Sergio Baldari
  • + 12 authors+ 7 authors

16 February 2022

Despite impressive results, almost 30% of NET do not respond to PRRT and no well-established criteria are suitable to predict response. Therefore, we assessed the predictive value of radiomics [68Ga]DOTATOC PET/CT images pre-PRRT in metastatic GEP NE...

(This article belongs to the Section Methods and Technologies Development)
  • Article
  • Open Access
3 Citations
3,704 Views
14 Pages

Chronic Tic Disorders in Youth: Clinical Phenotypes and Response to Pharmacological Treatment with Aripiprazole

  • Francesca Falcone,
  • Stefano Berloffa,
  • Gianluca Sesso,
  • Antonio Narzisi and ,
  • Elena Valente,
  • Valentina Viglione,
  • Gabriele Masi,
  • Annarita Milone and
  • Pamela Fantozzi
  • + 4 authors+ 0 author

29 November 2024

Background/Objectives: Tic disorders are neurodevelopmental conditions often associated with comorbidities like attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD). Our aims were: (a) in a sample of youth with tic disor...

(This article belongs to the Collection Emotional and Behavioral Problems in Children and Adolescents: Assessment and Intervention)