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124 Results Found

  • Article
  • Open Access
21 Citations
12,577 Views
16 Pages

Assessment of Lumbar Extensor Muscles in the Context of Trunk Function, a Pilot Study in Healthy Individuals

  • Daniela Vlažná,
  • Peter Krkoška,
  • Matyáš Kuhn,
  • Filip Dosbaba and ,
  • Ladislav Batalik,
  • Eva Vlčková,
  • Stanislav Voháňka and
  • Blanka Adamová
  • + 3 authors+ 0 author

13 October 2021

A comprehensive assessment of trunk function, including the lumbar extensor muscles, appears to be important in various conditions affecting axial musculature. This pilot cross-sectional observational study aimed to define a battery of tests that com...

(This article belongs to the Special Issue Physical Exercise in Sports Sciences and Rehabilitation: Physiology, Clinical Applications and Real Practice)
  • Article
  • Open Access
6 Citations
2,961 Views
10 Pages

Gender Mediation in Adolescents’ Back Pain and Physical Fitness: A Cross-Sectional Study

  • Noelia González-Gálvez,
  • María Carrasco-Poyatos,
  • Raquel Vaquero-Cristóbal and
  • Pablo J. Marcos-Pardo

There is a lack of studies that analyze the interaction between risk variables as predictors of back pain (BP) in adolescents. The objectives of this study were to examine the relationship between BP and several risk variables, and to analyze the eff...

(This article belongs to the Special Issue Pediatric Spine Health)
  • Article
  • Open Access
6 Citations
2,349 Views
15 Pages

Do Lumbar Paravertebral Muscle Properties Show Changes in Mothers with Moderate-Severity Low Back Pain Following a Cesarean Birth? A Case–Control Study

  • Mohamed G. Ali,
  • Abeer A. Mohammed,
  • Walaa M. Ragab,
  • Hoda M. Zakaria and ,
  • Reem M. Alwhaibi,
  • Zizi M. Ibrahim and
  • Rehab S. Mamoon
  • + 2 authors+ 0 author

23 January 2025

Background/Objectives: Cesarean birth (CB) is linked to nonspecific low back pain (NSLBP). Different properties of the muscular tissue, including contractile, biomechanical, and viscous properties, may reflect its physiological or pathological condit...

(This article belongs to the Special Issue Advances in the Diagnosis and Management of Low Back Pain: A Multidisciplinary Approach)
  • Article
  • Open Access
4 Citations
2,327 Views
14 Pages

Prognostic Value of the Goutallier Scale for Paravertebral Muscle Atrophy in Predicting Disability and Pain Outcomes in Degenerative Lumbar Spinal Stenosis: A Longitudinal Cohort Study of 100 Patients

  • Giuseppe Corazzelli,
  • Sergio Corvino,
  • Chiara Di Domenico,
  • Federico Russo and ,
  • Vincenzo Meglio,
  • Settimio Leonetti,
  • Valentina Pizzuti,
  • Marco Santilli,
  • Alessandro D’Elia and
  • Gualtiero Innocenzi
  • + 10 authors+ 5 authors

Background/Objectives: Degenerative lumbar spinal stenosis (LSS) is a prevalent cause of disability in elderly populations, often treated with decompressive surgery. However, postoperative functional outcomes are variable and influenced by factors be...

(This article belongs to the Special Issue Diagnosis, Therapy and Rehabilitation in Neuromuscular Diseases)
  • Article
  • Open Access
769 Views
14 Pages

Cervical Multifidus Fatty Degeneration and Bony Foraminal Stenosis Are Associated with Unsuccessful Response to Stellate Ganglion Block in Cervical Radicular Pain: A Retrospective Study

  • Hyun-Jung Kwon,
  • Daeyun Choi,
  • Shin Wook Yi,
  • Jun-Seok Lee and ,
  • Jin-Woo Shin,
  • Seong-Soo Choi,
  • Doo-Hwan Kim and
  • Chan-Sik Kim
  • + 3 authors+ 0 author

5 June 2026

Background and Objectives: Ultrasound-guided stellate ganglion block is a promising alternative intervention for cervical radicular pain. However, factors associated with treatment responses remain unknown. This single-center, retrospective study aim...

(This article belongs to the Special Issue Anesthesiology, Resuscitation, and Pain Management)
  • Article
  • Open Access
483 Views
17 Pages

Equivalent Clinical Outcomes but Divergent Biological Adaptation After Anterior Cervical Discectomy and Fusion Versus Cervical Disc Arthroplasty: A Longitudinal MRI Cohort Study

  • Evren Sönmez,
  • Lokman Ayhan,
  • Said Onar,
  • Ergin Anlı and ,
  • Abdurrahim Tekin,
  • Engin Can,
  • Selçuk Yapar,
  • Akın Öztürk,
  • Suna Dilbaz and
  • Serdar Çevik
  • + 6 authors+ 1 author

6 August 2026

Background/Objectives: Anterior cervical discectomy and fusion (ACDF) and cervical disc arthroplasty (CDA) can produce comparable short-term clinical outcomes, but their regional effects on cervical muscle morphology are incompletely characterized. T...

(This article belongs to the Special Issue Advances in Cervical Spine Surgery: Techniques, Outcomes, and Complications)
  • Article
  • Open Access
8 Citations
2,637 Views
10 Pages

Reliability of Gradient-Echo Magnetic Resonance Elastography of Lumbar Muscles: Phantom and Clinical Studies

  • Tsyh-Jyi Hsieh,
  • Ming-Chung Chou,
  • Yi-Chu Chen,
  • Yi-Chen Chou and ,
  • Chien-Hung Lin and
  • Clement Kuen-Huang Chen
  • + 1 author+ 0 author

Magnetic resonance elastography (MRE) has been used to successfully characterize the mechanical behavior of healthy and diseased muscles, but no study has been performed to investigate the reliability of MRE on lumbar muscles. The objective of this w...

(This article belongs to the Special Issue Advanced MRI Techniques for Musculoskeletal Imaging 2.0)
  • Article
  • Open Access
1,542 Views
9 Pages

Vertebral Ankylosis Is Associated with Reduced Cervical Extensor Muscle Bulk and Increased Fatty Degeneration

  • Junho Song,
  • Austen D. Katz,
  • Alex Ngan,
  • Andrew C. Hecht and ,
  • Sheeraz A. Qureshi and
  • Sohrab Virk
  • + 1 author+ 0 author

24 December 2025

Background/Objectives: Ankylosing spondylitis and diffuse idiopathic skeletal hyperostosis produce long-segment spinal ankylosis, altered biomechanics, and high fracture risk in the cervical spine. Paraspinal muscle degeneration (“spine-specifi...

(This article belongs to the Special Issue Spine Surgery: Clinical Advances and Practice Updates)
  • Case Report
  • Open Access
5 Citations
3,972 Views
11 Pages

Extra-Neural Metastases of Late Recurrent Myxopapillary Ependymoma to Left Lumbar Paravertebral Muscles: Case Report and Review of the Literature

  • Ciro Mastantuoni,
  • Fabio Tortora,
  • Roberto Tafuto,
  • Mario Tortora and ,
  • Francesco Briganti,
  • Raduan Ahmed Franca,
  • Rosa Della Monica,
  • Mariella Cuomo,
  • Lorenzo Chiariotti and
  • Teresa Somma
  • + 6 authors+ 1 author

10 September 2022

Ependymomas are commonly classified as low-grade tumors, although they may harbor a malignant behavior characterized by distant neural dissemination and spinal drop metastasis. Extra-CNS ependymoma metastases are extremely rare and only few cases hav...

(This article belongs to the Special Issue Advances in Diagnosis and Treatment of Brain Tumors and Nervous System Tumors)
  • Article
  • Open Access
2 Citations
2,039 Views
11 Pages

Clinical Outcomes and Risk Factors Associated with Spinal Kyphotic Deformity Following Osteoporotic Vertebral Fracture

  • Hayato Oishi,
  • Keishi Maruo,
  • Tomoyuki Kusukawa,
  • Tetsuto Yamaura and ,
  • Kazuma Nagao,
  • Masakazu Toi,
  • Masaru Hatano,
  • Fumihiro Arizumi,
  • Norichika Yoshie and
  • Toshiya Tachibana
  • + 5 authors+ 0 author

17 April 2025

Background: Osteoporotic vertebral fractures (OVFs) often lead to poor global sagittal alignment (GSA) and reduced quality of life (QOL). While pseudarthrosis and kyphotic deformities are well-known predictors of conservative treatment failure, the i...

(This article belongs to the Special Issue Clinical Advances in Minimally Invasive Spinal Treatment)
  • Article
  • Open Access
9 Citations
3,535 Views
12 Pages

Surrogates of Muscle Mass on Cardiac MRI Correlate with Exercise Capacity in Patients with Fontan Circulation

  • Kevin L. Smith,
  • Emile B. Gordon,
  • Megan E. Gunsaulus,
  • Adam Christopher and ,
  • Laura J. Olivieri,
  • Sameh S. Tadros,
  • Tyler Harris,
  • Anita P. Saraf,
  • Jacqueline Kreutzer and
  • Tarek Alsaied
  • + 6 authors+ 1 author

4 April 2023

Background: Sarcopenia is an increasingly recognized marker of frailty in cardiac patients. Patients with a history of congenital heart disease and Fontan procedure have a higher risk of developing progressive muscle wasting. Our objective was to det...

(This article belongs to the Section Cardiology)
  • Article
  • Open Access
7 Citations
1,761 Views
17 Pages

The Paraspinal Sarcopenia at the Upper Instrumented Vertebra Is a Predictor of Discoligamentous but Not Bony Proximal Junctional Kyphosis

  • Zach Pennington,
  • Anthony L. Mikula,
  • Abdelrahman Hamouda,
  • Maria Astudillo Potes and ,
  • Ahmad Nassr,
  • Brett A. Freedman,
  • Arjun S. Sebastian,
  • Jeremy L. Fogelson and
  • Benjamin D. Elder
  • + 4 authors+ 0 author

12 February 2025

Background/Objectives: Both poor bone quality and paraspinal sarcopenia have been suggested as risk factors for proximal junctional kyphosis (PJK) at the upper instrumented vertebra (UIV) following long-segment thoracolumbar fusion. Methods: Adults &...

(This article belongs to the Section Orthopedics)
  • Systematic Review
  • Open Access
13 Citations
11,923 Views
11 Pages

23 September 2023

Dysfunctions of the lumbosacral area and related pain syndromes, such as chronic low back pain (CLBP), are among the most common musculoskeletal problems in modern society. The purpose of this study was to evaluate the effectiveness of isolated myofa...

(This article belongs to the Section Orthopedics)
  • Article
  • Open Access
3 Citations
2,948 Views
10 Pages

Associations of Texture Features of Proton Density Fat Fraction Maps between Lumbar Vertebral Bone Marrow and Paraspinal Musculature

  • Yannik Leonhardt,
  • Michael Dieckmeyer,
  • Florian Zoffl,
  • Georg C. Feuerriegel and ,
  • Nico Sollmann,
  • Daniela Junker,
  • Tobias Greve,
  • Christina Holzapfel,
  • Hans Hauner and
  • Egon Burian
  • + 11 authors+ 6 authors

Chemical shift encoding-based water–fat MRI (CSE-MRI)-derived proton density fat fraction (PDFF) has been used for non-invasive assessment of regional body fat distributions. More recently, texture analysis (TA) has been proposed to reveal even...

(This article belongs to the Special Issue Regenerative Medicine for Bone and Cartilage and Pathophysiology of Degenerative Diseases)
  • Article
  • Open Access
3 Citations
2,765 Views
17 Pages

Fractal Features of Muscle to Quantify Fatty Infiltration in Aging and Pathology

  • Annamaria Zaia,
  • Martina Zannotti,
  • Lucia Losa and
  • Pierluigi Maponi

The physiological loss of muscle mass and strength with aging is referred to as “sarcopenia”, whose combined effect with osteoporosis is a serious threat to the elderly, accounting for decreased mobility and increased risk of falls with c...

(This article belongs to the Section Complexity)
  • Article
  • Open Access
3 Citations
3,764 Views
12 Pages

8 December 2020

To investigate and compare trunk control and muscle activation during uncompensated sitting in children with and without spinal cord injury (SCI). Static sitting trunk control in ten typically developing (TD) children (5 females, 5 males, mean (SD) a...

(This article belongs to the Section Pediatric Neurology & Neurodevelopmental Disorders)
  • Article
  • Open Access
555 Views
16 Pages

3 August 2026

Background/Objectives: Traditional Mongolian Rhythmical Vibration Therapy (RVT) is a manual intervention utilizing low-frequency mechanical oscillations, yet its biomechanical effects lack objective quantification. The present study aimed to evaluate...

(This article belongs to the Special Issue Advances in Manual Therapy: Diagnostics, Prevention and Treatment)
  • Article
  • Open Access
9 Citations
8,167 Views
11 Pages

Injuries and Strength Training Practices in Collegiate Tennis

  • Ecaterina Vasenina,
  • William B. Hammert,
  • Ryo Kataoka,
  • Scott J. Dankel and
  • Samuel L. Buckner

29 September 2022

Strength and conditioning practices may influence injury rates in the sport of tennis. Methods: Coaches reported the number injuries over the past year. Coaches were also surveyed on whether their training program included training related to upper-b...

(This article belongs to the Special Issue Sports Injury: Prevention and Rehabilitation)
  • Article
  • Open Access
5 Citations
2,096 Views
16 Pages

Effects of Age and Muscle Activation on Three-Dimensional Spine Kinematics and Asymmetry in Elderly Adults

  • Asghar Rezaei,
  • Chih-Hsiu Cheng,
  • Robert J. Pignolo,
  • Lichun Lu and
  • Kenton Kaufman

27 February 2025

Background/Objectives: Limited spinal range of motion (ROM) is linked to low back disorders, emphasizing the need to maintain mobility in the elderly. This study measured maximum spinal ROM, asymmetrical patterns, and the effects of age and muscle ac...

(This article belongs to the Special Issue Latest Developments in Minimally Invasive Spinal Treatment—2nd Edition)
  • Review
  • Open Access
30 Citations
9,596 Views
11 Pages

Ultrasound Imaging and Guidance for Cervical Myofascial Pain: A Narrative Review

  • Vincenzo Ricci,
  • Kamal Mezian,
  • Ke-Vin Chang,
  • Domiziano Tarantino and ,
  • Orhan Güvener,
  • Fabrizio Gervasoni,
  • Ondřej Naňka and
  • Levent Özçakar
  • + 3 authors+ 0 author

Cervical myofascial pain is a very common clinical condition in the daily practice of musculoskeletal physicians. Physical examination is currently the cornerstone for evaluating the cervical muscles and identifying the eventual presence of myofascia...

(This article belongs to the Special Issue Musculoskeletal Injuries, Rehabilitation and Impact on Public Health)
  • Review
  • Open Access
22 Citations
8,672 Views
15 Pages

Arteriogenesis of the Spinal Cord—The Network Challenge

  • Florian Simon,
  • Markus Udo Wagenhäuser,
  • Albert Busch,
  • Hubert Schelzig and
  • Alexander Gombert

22 February 2020

Spinal cord ischemia (SCI) is a clinical complication following aortic repair that significantly impairs the quality and expectancy of life. Despite some strategies, like cerebrospinal fluid drainage, the occurrence of neurological symptoms, such as...

(This article belongs to the Special Issue Arteriogenesis and Therapeutic Neovascularization)
  • Article
  • Open Access
10 Citations
4,747 Views
17 Pages

High Intensity Training Increases Muscle Area Occupied by Type II Muscle Fibers of the Multifidus Muscle in Persons with Non-Specific Chronic Low Back Pain: A Pilot Trial

  • Anouk Agten,
  • Jonas Verbrugghe,
  • Sjoerd Stevens,
  • Bert O. Eijnde and ,
  • Annick Timmermans and
  • Frank Vandenabeele
  • + 1 author+ 0 author

7 April 2021

Low back pain is a prevalent musculoskeletal disorder with high disability. Although exercise therapy is an important part of the multidisciplinary treatment of non-specific chronic low back pain (NSCLBP), the impact of exercise therapy on muscle mor...

(This article belongs to the Special Issue Musculoskeletal Rehabilitation)
  • Article
  • Open Access
608 Views
15 Pages

Association Between Lower Instrumented Vertebra Selection and Mechanical Complications After Surgical Correction for Kyphotic Deformity Following Osteoporotic Vertebral Fracture

  • Keishi Maruo,
  • Fumihiro Arizumi,
  • Kazuya Kishima,
  • Tetsuto Yamaura and ,
  • Masaru Hatano,
  • Hayato Oishi and
  • Toshiya Tachibana
  • + 2 authors+ 0 author

25 February 2026

Background: Kyphotic deformity following osteoporotic vertebral fracture (KDOVF) often requires corrective surgery to restore sagittal alignment; however, mechanical complications, such as proximal junctional failure (PJF) and distal junctional failu...

(This article belongs to the Section Orthopedics)
  • Case Report
  • Open Access
6 Citations
4,490 Views
9 Pages

Treatment Dilemma in Children with Late-Onset Pompe Disease

  • Martha Caterina Faraguna,
  • Viola Crescitelli,
  • Anna Fornari,
  • Silvia Barzaghi and ,
  • Salvatore Savasta,
  • Thomas Foiadelli,
  • Daniele Veraldi,
  • Matteo Paoletti,
  • Anna Pichiecchio and
  • Serena Gasperini
  • + 5 authors+ 0 author

30 January 2023

In recent years, there has been a significant increase in the diagnosis of asymptomatic Late-Onset Pompe Disease (LOPD) patients, who are detected via family screening or Newborn Screening (NBS). The dilemma is when to start Enzyme Replacement Therap...

(This article belongs to the Special Issue Genetic Research in Metabolic Diseases)
  • Article
  • Open Access
5 Citations
3,569 Views
8 Pages

Association between the Horizontal Gaze Ability and Physical Characteristics of Patients with Dropped Head Syndrome

  • Tatsuya Igawa,
  • Ken Ishii,
  • Ryunosuke Urata,
  • Akifumi Suzuki and ,
  • Hideto Ui,
  • Kentaro Ideura,
  • Norihiro Isogai,
  • Yutaka Sasao and
  • Haruki Funao
  • + 4 authors+ 0 author

23 March 2022

Background and Objectives: Patients with dropped head syndrome exhibit weakness of the cervical paraspinal muscles. However, the relationship between horizontal gaze disorder and physical function remains unclear. This study aimed to examine and clar...

(This article belongs to the Special Issue Minimally Invasive Spinal Treatment (MIST)—a New Concept in the Treatment of Spinal Diseases)
  • Article
  • Open Access
11 Citations
13,988 Views
9 Pages

Botulinum Neurotoxin Injections in Childhood Opisthotonus

  • Mariam Hull,
  • Mered Parnes and
  • Joseph Jankovic

12 February 2021

Opisthotonus refers to abnormal axial extension and arching of the trunk produced by excessive contractions of the paraspinal muscles. In childhood, the abnormal posture is most often related to dystonia in the setting of hypoxic injury or a number o...

(This article belongs to the Section Bacterial Toxins)
  • Article
  • Open Access
2 Citations
3,167 Views
9 Pages

Iliopsoas Muscle Weakness as a Key Diagnostic Marker in HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP)

  • Eiji Matsuura,
  • Satoshi Nozuma,
  • Mika Dozono,
  • Daisuke Kodama and ,
  • Masakazu Tanaka,
  • Ryuji Kubota and
  • Hiroshi Takashima
  • + 2 authors+ 0 author

Human T-cell leukemia virus-1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a slowly progressive neurological disease that arises from HTLV-1 infection. Pathologically, the condition is characterized by diffuse myelitis, wh...

(This article belongs to the Special Issue New Directions in HTLV-1 Research)
  • Article
  • Open Access
1,106 Views
22 Pages

Feasibility and Reliability of an Automated Muscle Segmentation Pipeline Linking Thoracic Supine Kyphosis and Trunk Muscle–Fat% on CT

  • Tianxi Liang,
  • Rian Atri,
  • Sarah Joseph,
  • Yiyuan Shao and ,
  • Zhitong Zou,
  • Adrian J. Villanueva,
  • Aida Y. Prince,
  • Renke Deng,
  • Kurt Teichman and
  • Martin R. Prince
  • + 6 authors+ 1 author

Background: As muscles atrophy, myocytes are replaced by fat and muscle strength diminishes, increasing thoracic supine kyphosis. Here, we investigate the relationship between muscle fat percentage (muscle–fat%) and thoracic supine kyphosis on...

(This article belongs to the Section Artificial Intelligence in Medical Imaging)
  • Article
  • Open Access
4 Citations
2,870 Views
14 Pages

The Fate of Pre-Existing L5-S1 Degeneration following Oblique Lumbar Interbody Fusion of L4-L5 and Above

  • Dong-Ho Kang,
  • Ji Hwan Kim,
  • Bong-Soon Chang,
  • Hyoungmin Kim and ,
  • Dongook Kim,
  • Sanghyun Park,
  • Seong Hwa Hong and
  • Sam Yeol Chang
  • + 3 authors+ 0 author

1 December 2023

Background: Previous studies have identified various risk factors for adjacent segment disease (ASD) at the L5-S1 level after fusion surgery, including preoperative sagittal imbalance, longer fusion, and preoperative disc degeneration. However, only...

(This article belongs to the Section Orthopedics)
  • Article
  • Open Access
178 Views
14 Pages

29 October 2026

Backgroundand Objectives: Soft tissue mobilization is commonly used to manage low back pain (LBP), but it remains unclear whether treatment outcomes differ according to the anatomical region targeted. To compare the effects of soft tissue mobilizatio...

(This article belongs to the Special Issue Physiotherapy in Musculoskeletal Pain: Assessment and Management—2nd Edition)
  • Review
  • Open Access
14 Citations
5,791 Views
19 Pages

3 November 2021

Muscle architectural parameters play a crucial role in the rate of force development, strength, and sports performance. On the other hand, deteriorated muscle architectural parameters are associated with injuries, sarcopenia, mortality, falls, and fr...

(This article belongs to the Special Issue Muscle Morphology: The Role in Human Body Performance-Functionality and Training Induced Adaptations)
  • Article
  • Open Access
9 Citations
7,571 Views
17 Pages

20 March 2025

Background/Objectives: Low back pain (LBP) may be related to intramuscular fatty infiltration (FI), the topography of which has been the subject of only a few studies. Our goal is therefore to determine the importance and topography of FI at the lumb...

(This article belongs to the Topic Orthopaedic Diseases and Innovative Intervention Strategies, 2nd Volume)
  • Study Protocol
  • Open Access
1 Citations
1,201 Views
12 Pages

Myotonometric, Static Plantar Pressure, and Stabilometric Assessment in Children and Adolescents with Idiopathic Scoliosis: A Study Protocol

  • Oana-Cristina Rădulescu,
  • Alina-Daniela Totorean,
  • Oana Suciu,
  • Andreea Niță and ,
  • Liliana Catan,
  • Alessandro Iatarola,
  • Iuliu Șerban and
  • Elena-Constanta Amaricai
  • + 3 authors+ 0 author

11 January 2026

Adolescent idiopathic scoliosis (AIS) is a 3D structural deformity of the spine that can cause decreased spinal movement, paraspinal muscle weakness, or chronic pain. Our study aims to evaluate biomechanical and viscoelastic properties of the paraver...

(This article belongs to the Special Issue Novel Therapeutics for Musculoskeletal Disorders)
  • Article
  • Open Access
4 Citations
6,430 Views
11 Pages

Resistance exercise with devices offering mechanisms to isolate the lumbar spine is effective to improve muscle strength and clinical outcomes. However, previously assessed devices with these mechanisms are not conducive for home exercise programs. T...

(This article belongs to the Special Issue Exercise Evaluation and Prescription—2nd Edition)
  • Communication
  • Open Access
5 Citations
4,132 Views
11 Pages

People Lifting Patterns—A Reference Dataset for Practitioners

  • Konrad Kluwak,
  • Ryszard Klempous,
  • Zenon Chaczko,
  • Jerzy W. Rozenblit and
  • Marek Kulbacki

30 April 2021

Many health professionals do not use correct person transfer techniques in their daily practice. This results in damage to the paraspinal musculature over time, resulting in lower back pain and injuries. In this work, we propose an approach for the a...

(This article belongs to the Collection Sensors for Gait, Human Movement Analysis, and Health Monitoring)
  • Article
  • Open Access
470 Views
22 Pages

Background/Objectives: The aim of this study was to precisely characterize neurological deficits in patients with idiophatic scoliosis (IS) by comparing preoperative clinical and neurophysiological examination results in patients with Lenke 1 and 3 s...

(This article belongs to the Section Neurotechnology and Neuroimaging)
  • Interesting Images
  • Open Access
476 Views
6 Pages

Inclusion-Body Myopathy with Paget Disease of the Bone and Frontotemporal Dementia (IBMPFD) with SCN4A Mutation: Modifying Factor or Not?

  • Sekai Tsujimoto,
  • Koji Hayashi,
  • Mamiko Sato,
  • Toshio Hamada and ,
  • Asuka Suzuki,
  • Yuka Nakaya,
  • Toyoaki Miura,
  • Ichizo Nishino,
  • Wakako Yoshioka and
  • Yasutaka Kobayashi
  • + 5 authors+ 0 author

3 September 2026

A 56-year-old man with a family history of myopathy developed generalized muscle weakness at age 45. At age 52, he was diagnosed with inclusion-body myopathy with Paget disease of bone and frontotemporal dementia (IBMPFD), confirmed by muscle patholo...

(This article belongs to the Special Issue Advances in the Diagnosis of Nervous System Diseases—3rd Edition)
  • Article
  • Open Access
989 Views
21 Pages

Purpose: To develop a fully automated 2D nnU-Net pipeline for multi-class skeletal muscle segmentation (psoas, paraspinal, and abdominal wall) at the third lumbar (L3) vertebral level, and to quantitatively evaluate its diagnostic performance and rel...

  • Article
  • Open Access
12 Citations
5,727 Views
12 Pages

Balance requires constant adjustments in muscle activation to attain force steadiness. Creating appropriate training can be challenging. The purpose of this study was to examine the effects of 2 weeks of front squat instability training using a water...

(This article belongs to the Special Issue Movement and Balance)
  • Review
  • Open Access
604 Views
18 Pages

Magnetic Resonance Imaging Segmentation of Soft Tissue in the Diagnosis of Chronic Low Back Pain: A Scoping Review

  • Wiktoria Frącz,
  • Anita Bilska,
  • Jakub Matuska,
  • Pablo Herrero and
  • Elżbieta Skorupska

Background/Objectives: Despite the substantial clinical and socioeconomic burden of chronic low back pain (CLBP), objective diagnostic biomarkers remain limited. Structural alterations of the lumbosacral muscles, particularly muscle atrophy and fatty...

(This article belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
  • Feature Paper
  • Article
  • Open Access
1,856 Views
15 Pages

Evaluation of Attenuation of Lumbar Epaxial Musculature in Dogs with Spinal Pathology

  • Robert Cristian Purdoiu,
  • Ionuț Claudiu Voiculeț,
  • Joana Alexandra Aldea,
  • Radu Lăcătuș and ,
  • Teodora Patrichi,
  • Felix Daniel Lucaci,
  • Tatjana Chan,
  • Patrick Kircher and
  • Sorin Marian Mârza
  • + 4 authors+ 0 author

19 May 2025

This study evaluated attenuation values of lumbar epaxial musculature in dogs with acute spinal pathology using computed tomography (CT) and compared them with values in dogs without spinal disease. Sixty client-owned dogs were included: thirty dogs...

(This article belongs to the Special Issue New Advances in Canine and Feline Diagnostics—2nd Edition)
  • Article
  • Open Access
25 Citations
4,366 Views
15 Pages

Incidence, Risk Factors, and Outcomes of Symptomatic Bone Cement Displacement following Percutaneous Kyphoplasty for Osteoporotic Vertebral Compression Fracture: A Single Center Study

  • Junbo Qi,
  • Yuanyu Hu,
  • Zhongwei Yang,
  • Yanlei Dong and ,
  • Xin Zhang,
  • Guojin Hou,
  • Yang Lv,
  • Yan Guo,
  • Fang Zhou and
  • Yun Tian
  • + 6 authors+ 1 author

19 December 2022

Study design: Retrospective. Background: Symptomatic bone cement displacement (BCD) is a rare complication following percutaneous kyphoplasty (PKP) interventions for osteoporotic vertebral compression fracture (OVCF). This study aimed to investigate...

(This article belongs to the Special Issue Orthopedic Surgery in Elderly Patients: Past, Present, and Future)
  • Article
  • Open Access
23 Citations
4,145 Views
15 Pages

Methylation of Estrogen Receptor 1 Gene in the Paraspinal Muscles of Girls with Idiopathic Scoliosis and Its Association with Disease Severity

  • Piotr Janusz,
  • Małgorzata Chmielewska,
  • Mirosław Andrusiewicz,
  • Małgorzata Kotwicka and
  • Tomasz Kotwicki

21 May 2021

Idiopathic scoliosis (IS) is a multifactorial disease with epigenetic modifications. Tissue dependent and differentially methylated regions (T-DMRs) may regulate tissue-specific expression of the estrogen receptor 1 gene (ESR1). This study aimed to a...

(This article belongs to the Special Issue Genetic Conditions Affecting the Skeleton: Congenital, Idiopathic Scoliosis and Arthrogryposis)
  • Article
  • Open Access
4 Citations
2,083 Views
14 Pages

Balance or Strength? Reconsidering Muscle Metrics in Sagittal Malalignment in Adult Sagittal Deformity Patients

  • Donghua Huang,
  • Zhan Wang,
  • Mihir Dekhne,
  • Atahan Durbas and ,
  • Tejas Subramanian,
  • Gabrielle Dykhouse,
  • Robert N. Uzzo,
  • Luis Felipe Colón,
  • Stephane Owusu-Sarpong and
  • Francis Lovecchio
  • + 6 authors+ 1 author

9 May 2025

Background/Objectives: Atrophy of the paraspinal and psoas major muscles is closely linked to sagittal malalignment in adult spinal deformity (ASD). However, most studies overlook the balance between these muscle groups. This study investigates the r...

(This article belongs to the Section Orthopedics)
  • Article
  • Open Access
1 Citations
3,090 Views
14 Pages

Acute Changes in Body Muscle Mass and Fat Depletion in Hospitalized Young Trauma Patients: A Descriptive Retrospective Study

  • Hassan Al-Thani,
  • Bianca M. Wahlen,
  • Ayman El-Menyar,
  • Mohammad Asim and ,
  • Lena Ribhi Nassar,
  • Mohamed Nadeem Ahmed,
  • Syed Nabir,
  • Monira Mollazehi and
  • Husham Abdelrahman
  • + 4 authors+ 0 author

11 September 2023

Background: Loss of muscle mass, and its strength, is associated with adverse outcomes in many medical and surgical conditions. Trauma patients may get malnourished during their hospital course due to many interrelated contributing factors. However,...

  • Article
  • Open Access
243 Views
17 Pages

1 October 2026

Background and Objectives: Conventional midline expansive open-door laminoplasty (EODL) may disrupt the posterior cervical extensor mechanism. This study compared 10-year outcomes after conventional midline and unilateral para-midline muscle-preservi...

  • Article
  • Open Access
1 Citations
2,002 Views
13 Pages

11 February 2026

Background: The viscoelastic properties of muscle tissue are important factors affecting muscle performance; they play a significant role in maintaining spinal stability, as well as muscle contraction and function. Changes in these properties can res...

  • Article
  • Open Access
1,638 Views
14 Pages

Are Reusable Dry Electrodes an Alternative to Gelled Electrodes for Canine Surface Electromyography?

  • Ana M. Ribeiro,
  • I. Brás,
  • L. Caldeira,
  • J. Caldeira and ,
  • C. Peham,
  • H. Plácido da Silva and
  • João F. Requicha
  • + 2 authors+ 0 author

13 October 2025

Despite its increasing use in veterinary rehabilitation, practical constraints—such as skin preparation and single-use electrodes—limit the wider adoption of surface electromyography (sEMG). Having conventional pre-gelled Ag/AgCl electrod...

(This article belongs to the Special Issue Small Animal Orthopedic Surgery, Physical Therapy and Rehabilitation—Second Edition)
  • Article
  • Open Access
2,452 Views
15 Pages

Efficacy of Transcatheter Renal Arterial Embolization to Contract Renal Size and Increase Muscle Mass in Patients with Polycystic Kidney Disease

  • Che-Ming Lin,
  • Tai-Shuan Lai,
  • Ting-Wei Liao,
  • Trianingsih and ,
  • Ying-Hui Wu,
  • Chun-Jung Cheng and
  • Chih-Horng Wu
  • + 2 authors+ 0 author

Background/Objectives: Autosomal dominant polycystic kidney disease (ADPKD) is a major cause of end-stage kidney disease (ESKD), accounting for approximately 5–10% of patients receiving dialysis worldwide. The large and numerous cysts in the li...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
35 Citations
15,146 Views
16 Pages

Randomized Trial of General Strength and Conditioning versus Motor Control and Manual Therapy for Chronic Low Back Pain on Physical and Self-Report Outcomes

  • Scott D. Tagliaferri,
  • Clint T. Miller,
  • Jon J. Ford,
  • Andrew J. Hahne and ,
  • Luana C. Main,
  • Timo Rantalainen,
  • David A. Connell,
  • Katherine J. Simson,
  • Patrick J. Owen and
  • Daniel L. Belavy
  • + 5 authors+ 0 author

Exercise and spinal manipulative therapy are commonly used for the treatment of chronic low back pain (CLBP) in Australia. Reduction in pain intensity is a common outcome; however, it is only one measure of intervention efficacy in clinical practice....

(This article belongs to the Section Epidemiology & Public Health)

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