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244,029 Results Found

  • Article
  • Open Access
10 Citations
3,521 Views
9 Pages

Unmethylated Insulin as an Adjunctive Marker of Beta Cell Death and Progression to Type 1 Diabetes in Participants at Risk for Diabetes

  • Kimber M. Simmons,
  • Alexandra Fouts,
  • Laura Pyle,
  • Pamela Clark,
  • Fran Dong,
  • Liping Yu,
  • Sahar Usmani-Brown,
  • Peter Gottlieb,
  • Kevan C. Herold and
  • The Type 1 Diabetes TrialNet Study Group
  • + 1 author

Islet autoantibody (iAb)-positive individuals have a high risk of progression to type 1 diabetes (T1D), although the rate of progression is highly variable and factors involved in the rate of progression are largely unknown. The ratio of unmethylated...

  • Article
  • Open Access
5 Citations
2,050 Views
26 Pages

7 June 2023

The aim of the present paper is to completely characterize the boundedness and compactness of a sum operator defined by some more complex products of composition, multiplication, and mth iterated radial derivative operators from Bloch-type spaces to...

  • Review
  • Open Access
165 Citations
26,492 Views
22 Pages

Differential Regulation of Type I and Type III Interferon Signaling

  • Megan L. Stanifer,
  • Kalliopi Pervolaraki and
  • Steeve Boulant

Interferons (IFNs) are very powerful cytokines, which play a key role in combatting pathogen infections by controlling inflammation and immune response by directly inducing anti-pathogen molecular countermeasures. There are three classes of IFNs: typ...

  • Article
  • Open Access
5 Citations
5,003 Views
16 Pages

The Therapeutic Effect of Botulinum Toxin Type A on Trigeminal Neuralgia: Are There Any Differences between Type 1 versus Type 2 Trigeminal Neuralgia?

  • Yan Tereshko,
  • Mariarosaria Valente,
  • Enrico Belgrado,
  • Chiara Dalla Torre,
  • Simone Dal Bello,
  • Giovanni Merlino,
  • Gian Luigi Gigli and
  • Christian Lettieri

14 November 2023

Background: Botulinum toxin type A is an effective treatment for trigeminal neuralgia. Moreover, its efficacy in type 2 trigeminal neuralgia and comparative studies between type 1 and type 2 trigeminal neuralgia (TN) still need to be improved. Method...

  • Review
  • Open Access
215 Citations
30,582 Views
14 Pages

Metabolomics of Type 1 and Type 2 Diabetes

  • Borros Arneth,
  • Rebekka Arneth and
  • Mohamed Shams

Type 1 and type 2 diabetes mellitus (DM) are chronic diseases that affect nearly 425 million people worldwide, leading to poor health outcomes and high health care costs. High-throughput metabolomics screening can provide vital insight into the patho...

  • Article
  • Open Access
19 Citations
4,765 Views
17 Pages

Rotavirus NSP1 Inhibits Type I and Type III Interferon Induction

  • Gennaro Iaconis,
  • Ben Jackson,
  • Kay Childs,
  • Mark Boyce,
  • Stephen Goodbourn,
  • Neil Blake,
  • Miren Iturriza-Gomara and
  • Julian Seago

31 March 2021

Type I interferons (IFNs) are produced by most cells in response to virus infection and stimulate a program of anti-viral gene expression in neighboring cells to suppress virus replication. Type III IFNs have similar properties, however their effects...

  • Article
  • Open Access
8 Citations
4,055 Views
12 Pages

The Interplay of Type 1, Type 2, and Type 3 Lymphocytes and Cytokines in Atopic Dermatitis

  • Keiichi Yamanaka,
  • Yui Kono,
  • Shohei Iida,
  • Takehisa Nakanishi,
  • Mai Nishimura,
  • Yoshiaki Matsushima,
  • Makoto Kondo,
  • Koji Habe and
  • Yasutomo Imai

7 February 2023

Atopic dermatitis (AD) is classified as a type 2 disease owing to the majority of type 2 lymphocytes that constitute the skin-infiltrating leukocytes. However, all of the type 1–3 lymphocytes intermingle in inflamed skin lesions. Here, using an...

  • Review
  • Open Access
52 Citations
9,270 Views
17 Pages

Systematic Review of Polygenic Risk Scores for Type 1 and Type 2 Diabetes

  • Felipe Padilla-Martínez,
  • Francois Collin,
  • Miroslaw Kwasniewski and
  • Adam Kretowski

Recent studies have led to considerable advances in the identification of genetic variants associated with type 1 and type 2 diabetes. An approach for converting genetic data into a predictive measure of disease susceptibility is to add the risk effe...

  • Article
  • Open Access
9 Citations
3,245 Views
12 Pages

20 October 2023

This paper presents an initial proposal for the utilization of mediative fuzzy logic in control problems. Mediative fuzzy logic (MFL) was originally proposed with the idea of modeling situations in which there exists contradictory knowledge among sev...

  • Article
  • Open Access
136 Views
17 Pages

20 January 2026

This paper introduces a generalized class of Weyl-type, Witt-type, and non-associative algebras constructed over an exponential–polynomial (expolynomial) framework. For fixed scalars ι1,,ιrA and for fixed integers p=(p1,...

  • Article
  • Open Access
4 Citations
3,179 Views
28 Pages

1 January 2023

Soundscapes are one of the main means of creating a religious atmosphere in Han Chinese Buddhist temples, which are the most important religious sites in China. This paper selected several representative forest-type and urban-type Han Chinese Buddhis...

  • Article
  • Open Access
1,840 Views
18 Pages

10 September 2023

In this paper, we address the study of the Kobayashi–Nomizu type and the Yano type connections on the tangent bundle TM equipped with the Sasaki metric. Then, we determine the curvature tensors of these connections. Moreover, we find conditions under...

  • Article
  • Open Access
38 Citations
6,610 Views
17 Pages

20 July 2017

This article focuses on the dynamic parameter adaptation in the harmony search algorithm using Type-1 and interval Type-2 fuzzy logic. In particular, this work focuses on the adaptation of the parameters of the original harmony search algorithm. At p...

  • Review
  • Open Access
8 Citations
4,154 Views
30 Pages

Role of Interleukins in Type 1 and Type 2 Diabetes

  • Roha Asif,
  • Ammara Khalid,
  • Tolga Mercantepe,
  • Aleksandra Klisic,
  • Sana Rafaqat,
  • Saira Rafaqat and
  • Filiz Mercantepe

Background: Despite distinct etiologies, type 1 diabetes (T1D) and type 2 diabetes (T2D) share chronic inflammation as a core feature. Interleukins, key immune mediators, play important yet still not fully understood roles in the development and comp...

  • Review
  • Open Access
13 Citations
6,054 Views
11 Pages

Mast Cells and the Pancreas in Human Type 1 and Type 2 Diabetes

  • Matilde Masini,
  • Mara Suleiman,
  • Michela Novelli,
  • Lorella Marselli,
  • Piero Marchetti and
  • Vincenzo De Tata

23 July 2021

Mast cells are highly differentiated, widely distributed cells of the innate immune system, that are currently considered as key regulators of both innate and adaptive immunity. Mast cells play a key role in health and survival mechanisms, especially...

  • Feature Paper
  • Article
  • Open Access
8 Citations
3,195 Views
9 Pages

We studied the properties of generalized solutions in unbounded domains and the asymptotic behavior of solutions of elliptic boundary value problems at infinity. Moreover, we studied the unique solvability of the mixed Dirichlet–Steklov-type an...

  • Article
  • Open Access
125 Citations
60,591 Views
15 Pages

Neuro Linguistic Programming (NLP) is a collection of techniques for personality development. Meta programmes, which are habitual ways of inputting, sorting and filtering the information found in the world around us, are a vital factor in NLP. Differ...

  • Article
  • Open Access
9 Citations
2,895 Views
20 Pages

Dynamic High-Type Interval Type-2 Fuzzy Logic Control for Photoelectric Tracking System

  • Shuwang Qin,
  • Chao Zhang,
  • Tao Zhao,
  • Wei Tong,
  • Qiliang Bao and
  • Yao Mao

14 March 2022

This paper proposes a dynamic high-type control (DHTC) method based on an interval type-2 fuzzy logic controller (IT2FLC), which is used in the photoelectric tracking system to improve the steady-state accuracy and response speed. Adding integrators...

  • Article
  • Open Access
4 Citations
4,217 Views
10 Pages

Identification of Silent Myocardial Ischemia in Patients with Long-Term Type 1 and Type 2 Diabetes

  • Dominika Rokicka,
  • Anna Bożek,
  • Marta Wróbel,
  • Alicja Nowowiejska-Wiewióra,
  • Aleksandra Szymborska-Kajanek,
  • Tomasz Stołtny,
  • Mariusz Gąsior and
  • Krzysztof Strojek

(1) Background: This study aimed to analyze epidemiological data to identify risk factors for silent myocardial ischemia in patients with long-term type 1 and type 2 diabetes. (2) Methods: An analysis was performed on 104 patients with long-term type...

  • Article
  • Open Access
22 Citations
10,305 Views
18 Pages

27 December 2019

This analysis highlights the significant role that domestic actors play in determining the outcomes of economic sanctions. It models the behavior of the main opposition party during an economic sanction episode, and introduces two commonly used varia...

  • Article
  • Open Access
18 Citations
7,670 Views
13 Pages

Disease-Specific Survival of Type I and Type II Epithelial Ovarian Cancers—Stage Challenges Categorical Assignments of Indolence & Aggressiveness

  • Edward J. Pavlik,
  • Christopher Smith,
  • Taylor S. Dennis,
  • Elizabeth Harvey,
  • Bin Huang,
  • Quan Chen,
  • Dava West Piecoro,
  • Brian T. Burgess,
  • Anthony McDowell and
  • John R. van Nagell
  • + 7 authors

Epithelial ovarian cancers (EOC) consist of several sub-types based on histology, clinical, molecular and epidemiological features that are termed “histo-types”, which can be categorized into less aggressive Type I and more aggressive Typ...

  • Communication
  • Open Access
2 Citations
2,367 Views
8 Pages

Transition from Screw-Type to Edge-Type Misfit Dislocations at InGaN/GaN Heterointerfaces

  • Quantong Li,
  • Albert Minj,
  • Yunzhi Ling,
  • Changan Wang,
  • Siliang He,
  • Xiaoming Ge,
  • Chenguang He,
  • Chan Guo,
  • Jiantai Wang and
  • Pierre Ruterana
  • + 2 authors

28 June 2023

We have investigated the interface dislocations in InxGa1−xN/GaN heterostructures (0 ≤ x ≤ 0.20) using diffraction contrast analysis in a transmission electron microscope. The results indicate that the structural properties of interface d...

  • Article
  • Open Access
3 Citations
1,478 Views
13 Pages

On Prešić-Type Mappings: Survey

  • Youssef Achtoun,
  • Milanka Gardasević-Filipović,
  • Slobodanka Mitrović and
  • Stojan Radenović

2 April 2024

This paper is dedicated to the memory of the esteemed Serbian mathematician Slaviša B. Prešić (1933–2008). The primary aim of this survey paper is to compile articles on Prešić-type mappings published since 1965....

  • Article
  • Open Access
15 Citations
6,896 Views
23 Pages

The Riccati System and a Diffusion-Type Equation

  • Erwin Suazo,
  • Sergei K. Suslov and
  • José M. Vega-Guzmán

15 May 2014

We discuss a method of constructing solutions of the initial value problem for diffusion-type equations in terms of solutions of certain Riccati and Ermakov-type systems. A nonautonomous Burgers-type equation is also considered. Examples include, but...

  • Article
  • Open Access
13 Citations
3,148 Views
8 Pages

A Prospective Study: Highlights of Hippocampal Spectroscopy in Cognitive Impairment in Patients with Type 1 and Type 2 Diabetes

  • Julia Samoilova,
  • Mariia Matveeva,
  • Olga Tonkih,
  • Dmitry Kudlau,
  • Oxana Oleynik and
  • Aleksandr Kanev

19 February 2021

Diabetes mellitus type 1 and 2 is associated with cognitive impairment. Previous studies have reported a relationship between changes in cerebral metabolite levels and the variability of glycemia. However, the specific risk factors that affect the me...

  • Review
  • Open Access
12 Citations
4,649 Views
25 Pages

21 May 2022

Paramyxoviridae is a viral family within the order of Mononegavirales; they are negative single-strand RNA viruses that can cause significant diseases in both humans and animals. In order to replicate, paramyxoviruses–as any other viruses&ndash...

  • Article
  • Open Access
10 Citations
3,618 Views
13 Pages

Fatigue Performance of Type I and Type II Fibre Bragg Gratings Fabricated by Femtosecond Laser Inscription through the Coating

  • Naizhong Zhang,
  • Suzana Turk,
  • Claire Davis,
  • Wing K. Chiu,
  • Tommy Boilard and
  • Martin Bernier

15 November 2022

Strain sensing technology using fibre Bragg grating (FBG) sensors is an attractive capability for aerospace structural health monitoring (SHM) and assessment because they offer resistance to harsh environments, low maintenance, and potential for high...

  • Article
  • Open Access
9 Citations
9,222 Views
10 Pages

Aging and the Impact of Solar Ultraviolet Radiation on the Expression of Type I and Type VI Collagen

  • Foteini Biskanaki,
  • Vasiliki Kefala,
  • Andreas C. Lazaris and
  • Efstathios Rallis

Both endogenous and exogenous factors cause skin aging. This study aimed to compare the differential expressions of collagen type I (COL I) and collagen type VI (COL VI) in skins with biological aging and photoaging. In order to comprehend the impact...

  • Article
  • Open Access
3 Citations
1,499 Views
12 Pages

New Hille Type and Ohriska Type Criteria for Nonlinear Third-Order Dynamic Equations

  • Taher S. Hassan,
  • Qingkai Kong,
  • Rami Ahmad El-Nabulsi and
  • Waranont Anukool

6 November 2022

The objective of this paper is to derive new Hille type and Ohriska type criteria for third-order nonlinear dynamic functional equations in the form of a2(ζ)φα2a1ζφα1xΔ(ζ)ΔΔ+q(ζ)φαx(...

  • Article
  • Open Access
2,069 Views
19 Pages

28 May 2020

In this paper, we introduce two new image-sharing types to extend the applicability of sharing. Type 1 is our so-called forbidden type. In its sharing system, any t of the n shares can recover the secret image, unless the t shares form a forbidden gr...

  • Review
  • Open Access
22 Citations
8,035 Views
13 Pages

13 March 2019

The aim of this review was to investigate existing guidelines and scientific evidence on determining insulin dosage in people with type 1 and type 2 diabetes, and in particular to check whether the prandial insulin dose should be calculated based on...

  • Article
  • Open Access
4 Citations
1,952 Views
26 Pages

8 June 2023

Comparative lifetime tests are extremely significant when the experimenters study the reliability of the comparative advantages of two products in competition. Considering joint type-II censoring, we deal with the inference when two product lines con...

  • Article
  • Open Access
1,416 Views
13 Pages

8 October 2024

Understanding the structural intricacies of RNA molecules is essential for deciphering numerous biological processes. Traditionally, scientists have relied on experimental methods to gain insights and draw conclusions. However, the recent advent of a...

  • Article
  • Open Access
21 Citations
6,379 Views
27 Pages

Mating-Type Locus Organization and Mating-Type Chromosome Differentiation in the Bipolar Edible Button Mushroom Agaricus bisporus

  • Marie Foulongne-Oriol,
  • Ozgur Taskent,
  • Ursula Kües,
  • Anton S. M. Sonnenberg,
  • Arend F. van Peer and
  • Tatiana Giraud

16 July 2021

In heterothallic basidiomycete fungi, sexual compatibility is restricted by mating types, typically controlled by two loci: PR, encoding pheromone precursors and pheromone receptors, and HD, encoding two types of homeodomain transcription factors. We...

  • Article
  • Open Access
14 Citations
5,494 Views
12 Pages

The purpose of this study was to investigate the knowledge, perceptions and concerns of individuals living with diabetes mellitus regarding the disorder and its associated long-term health complications. Individuals living with type 1 (N = 110) and t...

  • Article
  • Open Access
14 Citations
2,142 Views
11 Pages

1 November 2022

The objective of this work is focused on improving the optimization ability of the cuckoo search algorithm (CS), and, for this reason, a comparison is made between type-1 and interval type-2 fuzzy logic to look for more promising results in the cucko...

  • Article
  • Open Access
1,900 Views
15 Pages

22 March 2022

Recently, there has been increasing attention on the use of renewable energy in buildings, particularly, the photovoltaic thermal (PVT) system that uses both solar power and thermal energy. However, there is a limit to adopting the PVT system in real...

  • Article
  • Open Access
16 Citations
4,272 Views
14 Pages

Circulating Soluble CD36 is Similar in Type 1 and Type 2 Diabetes Mellitus versus Non-Diabetic Subjects

  • Esmeralda Castelblanco,
  • Lucía Sanjurjo,
  • Mireia Falguera,
  • Marta Hernández,
  • José-Manuel Fernandez-Real,
  • Maria-Rosa Sarrias,
  • Nuria Alonso and
  • Didac Mauricio

The aim of this study was to determine whether plasma concentrations of sCD36 (soluble CD36) are associated with the presence of type 1 or type 2 diabetes. Plasma levels of sCD36 were analysed in 1023 subjects (225 type 1 diabetes (T1D) patients, 276...

  • Article
  • Open Access
16 Citations
3,303 Views
10 Pages

Sulphur- and Selenium-for-Oxygen Replacement as a Strategy to Obtain Dual Type I/Type II Photosensitizers for Photodynamic Therapy

  • Mario Prejanò,
  • Marta Erminia Alberto,
  • Bruna Clara De Simone,
  • Tiziana Marino,
  • Marirosa Toscano and
  • Nino Russo

The effect on the photophysical properties of sulfur- and selenium-for-oxygen replacement in the skeleton of the oxo-4-dimethylaminonaphthalimide molecule (DMNP) has been explored at the density functional (DFT) level of theory. Structural parameters...

  • Article
  • Open Access
20 Citations
3,230 Views
11 Pages

Hybrid Contractions on Branciari Type Distance Spaces

  • Kamaleldin Abodayeh,
  • Erdal Karapınar,
  • Ariana Pitea and
  • Wasfi Shatanawi

19 October 2019

In this manuscript, we consider some hybrid contractions that merge linear and nonlinear contractions in the abstract spaces induced by the Branciari distance and the Branciari b-distance. More precisely, we introduce the notion of a ( p , c ) ...

  • Article
  • Open Access
474 Views
16 Pages

Lorentzian Structure and Curvature Analysis of Osculating Type-2 Ruled Surfaces via the Type-2 Bishop Frame

  • Mohammed Messaoudi,
  • Emad Solouma,
  • Mohammed N. Alshehri,
  • Abdulrahman F. Aljohani and
  • Marin Marin

30 October 2025

This study investigates the geometry of osculating type-2 ruled surfaces in Minkowski 3-space E13, formulated through the Type-2 Bishop frame associated with a spacelike curve whose principal normal is timelike and binormal is spacelike. Using the hy...

  • Article
  • Open Access
1 Citations
1,465 Views
22 Pages

The Promising Role of Selected Fibroblast Growth Factors as Potential Markers of Complications in Type 1 and Type 2 Diabetes

  • Elżbieta Cecerska-Heryć,
  • Jaśmina Michałów,
  • Weronika Engwert,
  • Julia Marciniak,
  • Radosław Birger,
  • Natalia Serwin,
  • Rafał Heryć,
  • Aleksandra Polikowska,
  • Małgorzata Goszka and
  • Barbara Dołęgowska
  • + 1 author

8 September 2025

Diabetes is a common chronic disease. Untreated diabetes may lead to complications such as nephropathy, neuropathy, retinopathy, and macroangiopathies. The main goal in treating diabetes is to limit the development of vascular complications. The FGF...

  • Article
  • Open Access
3 Citations
1,607 Views
18 Pages

21 June 2023

In this paper, we state and establish a new fixed point theorem for generalized Ćirić-type contraction in Kaleva-Seikkala’s type fuzzy b-metric space. Our results improve and extend some well-known results in the literature. Some exam...

  • Article
  • Open Access
2 Citations
1,938 Views
12 Pages

Immature Surfactant Protein Type B and Surfactant Protein Type D Correlate with Coronary Heart Disease in Patients with Type 2 Diabetes

  • Cristina Banfi,
  • Francesco Piarulli,
  • Eugenio Ragazzi,
  • Stefania Ghilardi,
  • Arianna Greco,
  • Annunziata Lapolla and
  • Giovanni Sartore

17 July 2024

Background: Different specific surfactant proteins (SPs) have been associated with various pathological conditions, not only of the respiratory system, but also more recently with cardiovascular diseases, such as heart failure. The aim of the present...

  • Article
  • Open Access
1 Citations
1,185 Views
18 Pages

Improved Hille-Type and Ohriska-Type Criteria for Half-Linear Third-Order Dynamic Equations

  • Taher S. Hassan,
  • Mnaouer Kachout,
  • Bassant M. El-Matary,
  • Loredana Florentina Iambor,
  • Ismoil Odinaev and
  • Akbar Ali

27 November 2024

In this paper, we examine the oscillatory behavior of solutions to a class of half-linear third-order dynamic equations with deviating arguments α2(η)ϕδ2α1ηϕδ1uΔ(η)ΔΔ+p(η)ϕ&delt...

  • Article
  • Open Access
11 Citations
3,421 Views
10 Pages

31 August 2020

Background: Limited data exist comparing how type 1 diabetes mellitus (DM) and type 2 DM may have differential effects on peripheral artery disease (PAD) severity. We aimed to study the association of type of DM with the procedure utilized in hospita...

  • Article
  • Open Access
3,763 Views
24 Pages

In today’s fierce market competition, enterprises must quickly attract consumers’ attention to products and prompt them to make purchases. Based on regulatory focus theory, this study examines the impact of the congruence between different types of g...

  • Article
  • Open Access
4,074 Views
21 Pages

Design and Testing of a New Type of Planetary Traction Drive Bearing-Type Reducer

  • Hongyu Shu,
  • Yijie Yu,
  • Ran Shu,
  • Wenjie Wang and
  • Changjiang Pan

4 February 2024

This paper presents the design and development of a new type of planetary traction drive bearing-type reducer. In this design, the transmission outer ring is replaced with an elastic ring. The design constructs a circular arc at the axial end of the...

  • Article
  • Open Access
3 Citations
1,683 Views
19 Pages

Engineering n-Type and p-Type BiOI Nanosheets: Influence of Mannitol on Semiconductor Behavior and Photocatalytic Activity

  • Shuo Yang,
  • Wenhui Li,
  • Kaiyue Li,
  • Ping Huang,
  • Yuquan Zhuo,
  • Keyan Liu,
  • Ziwen Yang and
  • Donglai Han

21 December 2024

Photocatalytic technology holds significant promise for sustainable development and environmental protection due to its ability to utilize renewable energy sources and degrade pollutants efficiently. In this study, BiOI nanosheets (NSs) were synthesi...

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