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  • Review
  • Open Access
6 Citations
6,450 Views
10 Pages

The most common complaint among patients with vestibular schwannoma (VS) is hearing loss. This significantly affects the quality of life before, during, and after treatment for patients with VS. Untreated hearing loss in VS patients may even lead to...

(This article belongs to the Special Issue Hearing and Balance in Acoustic Neuroma)
  • Article
  • Open Access
22 Citations
4,523 Views
11 Pages

Long-Term Outcomes of Stereotactic Radiosurgery for Trigeminal, Facial, and Jugular Foramen Schwannoma in Comparison with Vestibular Schwannoma

  • Yuki Shinya,
  • Hirotaka Hasegawa,
  • Masahiro Shin,
  • Takehiro Sugiyama,
  • Mariko Kawashima,
  • Atsuto Katano,
  • Akinori Kashio,
  • Kenji Kondo and
  • Nobuhito Saito

7 March 2021

Stereotactic radiosurgery (SRS) is known to provide excellent tumor control with functional preservation for vestibular schwannomas (VS), but its efficacy in the other major intracranial schwannomas including trigeminal (TS), facial (FS), and jugular...

(This article belongs to the Special Issue Schwannomas – So-Called Benign Nervous System Tumors)
  • Case Report
  • Open Access
5 Citations
1,069 Views
2 Pages

Gastric Schwannoma: A Case Report

  • Hayfa Romdhane,
  • Myriam Cheikh,
  • Zeineb Mzoughi,
  • Sana Ben Slama,
  • Rym Ennaifer and
  • Najet Belhadj

30 November 2016

Schwannomas are generally benign, slow growing tumors. They are rarely observed in the gastrointestinal tract with the most common site being the stomach. These tumors are usually asymptomatic. The preoperative diagnosis via endoscopy is a challengin...

  • Case Report
  • Open Access
1,296 Views
3 Pages

A Rare Case of Nasal Schwannoma of Middle Turbinate

  • Nilam U. Sathe,
  • Sheetal Shelke,
  • Hetal Marfatia and
  • Shampa Mishra

20 December 2016

Schwannoma is a benign, slow-growing nerve sheath tumor derived from the Schwann cells. Cases with nasal schwannoma arising from nasal septum and inferior turbinate have been reported, though being rare. A 32-yearold male patient presented to our hos...

  • Case Report
  • Open Access
4 Citations
2,836 Views
6 Pages

A Rare Case of a Gigantic Retroperitoneal Schwannoma

  • Nenad Koruga,
  • Borna Kovačić,
  • Alen Rončević,
  • Branko Dmitrović,
  • Zrinka Požgain,
  • Anamarija Soldo Koruga,
  • Tatjana Rotim,
  • Sonja Škiljić,
  • Hrvoje Vinković and
  • Tajana Turk

25 July 2024

Introduction: Schwannomas (Schs) are benign tumor masses that rarely occur intra-abdominally and rarely reach larger diameters. When present, they occur as rare solitary nerve sheath tumors of peri-neural Schwann cells. Schwannoma mostly affects the...

(This article belongs to the Section Neurology)
  • Article
  • Open Access
21 Citations
9,182 Views
13 Pages

Diagnostic and Therapeutic Strategy for Vagal Schwannoma: Case Series and Literature Review

  • Antonella Loperfido,
  • Alessandra Celebrini,
  • Bruno Fionda,
  • Gianluca Bellocchi and
  • Giovanni Cristalli

24 May 2023

Background and Objectives: Clinical management of vagal schwannoma is a real diagnostic and therapeutic challenge because the medical history and clinical examination are often non-specific and vagal nerve injury following surgical resection still re...

(This article belongs to the Special Issue Update on Otorhinolaryngologic Diseases)
  • Interesting Images
  • Open Access
6 Citations
3,200 Views
8 Pages

Schwannoma: A Rare Case of Submucosal Gastric Tumor

  • Cosmina Fugărețu,
  • Cătalin Mișarca,
  • Lucian Petcu,
  • Raluca Șoană,
  • Andrada Cîrnațiu,
  • Marin Valeriu Surlin,
  • Stefan Patrascu and
  • Sandu Ramboiu

Schwannoma is a tumor that originates from the Schwann cells that surround a neuron’s axon. This tumor is very rare in the gastrointestinal tract and develops submucosally from intestinal nerve plexuses. The most common location for gastrointes...

(This article belongs to the Special Issue Abdominal Surgical Diseases: Diagnosis, Treatment and Management 2.0)
  • Case Report
  • Open Access
1,233 Views
12 Pages

Gallbladder Schwannoma: A Case Report and Literature Review

  • Qinyu Liu,
  • Runze Huang,
  • Shujuan Ni,
  • Xin Jin,
  • Xuanci Bai,
  • Lu Wang and
  • Weiping Zhu

7 November 2025

Background and Clinical Significance: Schwannoma is a benign, encapsulated neurogenic neoplasm that originates from Schwann cells of the peripheral nerve sheath. While these tumors may develop in virtually any anatomical location, gallbladder schwann...

(This article belongs to the Section Pathology and Molecular Diagnostics)
  • Case Report
  • Open Access
1,888 Views
16 Pages

Lip Schwannoma—A Rare Presentation in a Pediatric Patient: Case Report and a Literature Review

  • Cinzia Casu,
  • Mara Pinna,
  • Andrea Butera,
  • Carolina Maiorani,
  • Girolamo Campisi,
  • Clara Gerosa,
  • Antonella Caiazzo,
  • Andrea Scribante and
  • Germano Orrù

Background/Objectives: Schwannoma is a rare tumor, typical in young adults, originating from the myelin sheath that surrounds Schwann cells. It can occur in any part of the Peripheral Nervous System (PNS). It develops in the head and neck region in 2...

(This article belongs to the Special Issue Advances in Dental Diagnostics)
  • Case Report
  • Open Access
4 Citations
956 Views
2 Pages

An Unusual Localization of Intraosseous Schwannoma: The Hamate Bone

  • Volkan Gurkan,
  • Cavide Sonmez,
  • Ayse Aralasmak,
  • Fatih Yildiz and
  • Ozgur Erdogan

23 February 2017

Intraosseous schwannoma of the hamate bone presented in this case is a very rare benign tumor, and its diagnosis combined with clinical, imaging and needle biopsy is important to guide further therapy. The diagnosis of schwannoma of the hamate was pr...

  • Interesting Images
  • Open Access
182 Views
6 Pages

Peripheral Nerve Schwannoma with an Unusual Anatomical Site

  • Alina Badlaeva,
  • Natalia Mezhelumova,
  • Natalia Arzhanukhina and
  • Dmitry Bulanov

1 October 2026

We present the case of a 40-year-old woman diagnosed with schwannoma at an infrequent localization. The patient complained of multiple painful lesions in the vulvar region and perianal fold, accompanied by intense, constant pain that slightly increas...

(This article belongs to the Special Issue Pathology in Practice: Diagnostic Insights from Clinical Cases)
  • Case Report
  • Open Access
2 Citations
3,448 Views
10 Pages

Neck Schwannoma Masking as Thyroid Tumour: Into the Deep of Diagnostics and Anatomy

  • Serghei Covantsev,
  • Anna Bumbu,
  • Anna Sukhotko,
  • Evghenii Zakurdaev,
  • Ivan Kuts and
  • Andrey Evsikov

19 October 2024

Schwannomas are benign nerve sheath tumours that exhibit a slow rate of growth. In the vast majority of cases, schwannomas manifest as asymptomatic masses. The presence of symptomatic lesions may necessitate surgical removal. The incidence of schwann...

(This article belongs to the Special Issue New Advances in Neurosurgery: Clinical Diagnosis, Treatment and Prognosis)
  • Review
  • Open Access
1 Citations
1,662 Views
14 Pages

Naso-Ethmoidal Schwannoma: From Pathology to Surgical Strategies

  • Sergio Corvino,
  • Oreste de Divitiis,
  • Giuseppe Corazzelli,
  • Jacopo Berardinelli,
  • Adriana Iuliano,
  • Chiara Di Domenico,
  • Vittoria Lanni,
  • Roberto Altieri,
  • Diego Strianese and
  • Giuseppe Mariniello
  • + 1 author

22 March 2025

Background: Naso-ethmoidal schwannoma is a rare slow-growing tumor arising from the Schwann cells of the sinonasal tract. This study discusses the evolution of surgical approaches to naso-ethmoidal schwannomas with respect to tumor growth and recent...

(This article belongs to the Section Clinical Research in Cancer)
  • Systematic Review
  • Open Access
2 Citations
1,459 Views
18 Pages

Esophageal Schwannoma—Systematic Review of Clinicopathologic Factors and Treatment

  • Rashad Khazen,
  • Raneem Bader,
  • George Asfour,
  • Barak Bar-Zakai,
  • Guy Pines and
  • Harbi Khalayleh

9 April 2026

Background: Esophageal schwannomas are extremely rare, benign mesenchymal tumors originating from the nerve sheath tissues of autonomic nerves, accounting for less than 2% of all esophageal tumors. This systematic review aims to provide a detailed an...

(This article belongs to the Special Issue Recent Clinical Advances in Esophageal Surgery)
  • Review
  • Open Access
34 Citations
11,828 Views
11 Pages

Vestibular schwannoma (VS) is a benign tumor that originates from Schwann cells in the vestibular component. Surgical treatment for VS has gradually declined over the past few decades, especially for small tumors. Gamma knife radiosurgery has become...

(This article belongs to the Special Issue Advances in Molecular Genetics of Brain Tumors)
  • Article
  • Open Access
1 Citations
1,666 Views
12 Pages

Clinical Diagnosis and Treatment in Patients with Schwannoma at a Single Institute

  • Tomoki Nakamura,
  • Ryohei Adachi,
  • Tomohito Hagi,
  • Yumi Matsuyama,
  • Hironori Date and
  • Masahiro Hasegawa

Background/Objectives: The aim of this study was to review the clinical course of schwannoma in 176 patients and elucidate the clinical outcome in a patient who received surgical treatment and one who did not. Methods: Between August 2006 and Decembe...

(This article belongs to the Special Issue Advances in the Diagnosis and Management of Musculoskeletal Tumors)
  • Article
  • Open Access
5 Citations
2,550 Views
11 Pages

Health-Related Quality of Life and Return to Work after Surgery for Spinal Schwannoma: A Population-Based Cohort Study

  • Aman Singh,
  • Ann-Christin von Vogelsang,
  • Victor Gabriel El-Hajj,
  • Ali Buwaider,
  • Alexander Fletcher-Sandersjöö,
  • Jenny Pettersson-Segerlind,
  • Erik Edström and
  • Adrian Elmi-Terander

15 May 2024

Spinal schwannomas are the second most common primary intradural spinal tumor. This study aimed to assess health-related quality of life (HRQoL) and the frequency of return to work after the surgical treatment of spinal schwannomas. HRQoL was compare...

(This article belongs to the Section Cancer Survivorship and Quality of Life)
  • Article
  • Open Access
1 Citations
2,060 Views
12 Pages

11 December 2024

Background/Objectives: Transcriptome profiling can reveal prognostic biomarkers and therapeutic vulnerabilities for directing clinical care. Currently, there are no biomarkers that can accurately predict patient prognosis regarding tumor growth and t...

(This article belongs to the Special Issue Cancer Biomarkers: Recent Progress, Innovations and Future Clinical Implications)
  • Article
  • Open Access
11 Citations
7,450 Views
11 Pages

Schwannoma of the Upper Limb: Retrospective Study of a Rare Tumor with Uncommon Locations

  • Mihaela Pertea,
  • Alexandru Filip,
  • Bogdan Huzum,
  • Sorinel Lunca,
  • Claudiu Carp,
  • Mihaela Mitrea,
  • Paula Toader,
  • Stefana Luca,
  • Dan Cristian Moraru and
  • Bogdan Veliceasa
  • + 1 author

Background: Although schwannoma (neurilemmoma) is the most common tumor of the peripheral nerve, its low incidence, slow growth and vague symptoms often lead to misdiagnosis or delayed diagnosis. The aim of the study is to present a series with a lar...

(This article belongs to the Special Issue Advances in the Diagnosis and Management of Tumors/Cancers)
  • Review
  • Open Access
16 Citations
5,525 Views
19 Pages

Extracranial Facial Nerve Schwannoma—Histological Surprise or Therapeutic Planning?

  • Daniela Vrinceanu,
  • Mihai Dumitru,
  • Matei Popa-Cherecheanu,
  • Andreea Nicoleta Marinescu,
  • Oana-Maria Patrascu and
  • Florin Bobirca

17 June 2023

Schwannomas (neurilemomas) are benign, slow-growing, encapsulated, white, yellow, or pink tumors originating in Schwann cells in the sheaths of cranial nerves or myelinated peripheral nerves. Facial nerve schwannomas (FNS) can form anywhere along the...

(This article belongs to the Special Issue Current Trends in Otorhinolaryngology and Head and Neck Pathology)
  • Review
  • Open Access
13 Citations
4,653 Views
16 Pages

Cochlear Implantation in Intralabyrinthine Schwannoma: Case Series and Systematic Review of the Literature

  • Sebastiano Franchella,
  • Marzia Ariano,
  • Francesca Bevilacqua,
  • Stefano Concheri and
  • Elisabetta Zanoletti

28 February 2023

Intralabyrinthine schwannomas (ILS) are rare benign tumours arising from the peripheral branches of the cochlear or vestibular nerves in the membranous labyrinth, intracochlear schwannomas being the most frequent ones. When hearing is no longer feasi...

(This article belongs to the Special Issue Hearing and Balance in Acoustic Neuroma)
  • Case Report
  • Open Access
18 Citations
1,099 Views
3 Pages

Gastric Schwannoma: A Benign Tumor Often Misdiagnosed as Gastrointestinal Stromal Tumor

  • Apurva S. Shah,
  • Pravin M. Rathi,
  • Vaibhav S. Somani and
  • Astha M. Mulani

12 October 2015

Gastric schwannomas are rare mesenchymal tumors that arise from the nerve plexus of gut wall. They present with nonspecific symptoms and are often detected incidentally. Preoperative investigation is not pathognomic and many are therefore misdiagnose...

  • Case Report
  • Open Access
1 Citations
2,798 Views
5 Pages

16 July 2024

Schwannomas are benign and slow-growing peripheral nerve sheath neoplasms of Schwann cells. These are generally encountered in the neck, head, and flexor areas of the extremities. Even though many schwannomas are easily diagnosable, their variable mo...

(This article belongs to the Section Neurology)
  • Case Report
  • Open Access
1 Citations
3,552 Views
6 Pages

Schwannoma of the Hypoglossal Nerve Mimicking Carotid Body Paraganglioma

  • Maximilian Linxweiler,
  • Wolfgang Reith,
  • Mathias Wagner,
  • Jan Philipp Kühn and
  • Bernhard Schick

Carotid body paragangliomas (CBPs) clinically present as highly vascularized cervical masses with a pathognomonic localization at the carotid artery bifurcation. Following ultrasonography and MRI/CT imaging, surgical resection with optional preoperat...

(This article belongs to the Section Pathology and Molecular Diagnostics)
  • Systematic Review
  • Open Access
5 Citations
3,511 Views
14 Pages

Primary Cardiac Schwannoma: A Meta-Analysis of Individual Case Reports

  • Mohamed Rahouma,
  • Massimo Baudo,
  • Sherif Khairallah,
  • Anas Dabsha,
  • Alessandro Tafuni,
  • Magdy M. El-Sayed Ahmed,
  • Christopher Lau,
  • Erin Iannacone,
  • Yoshifumi Naka and
  • Stephanie L. Mick
  • + 3 authors

9 May 2023

Primary cardiac schwannoma (PCS) is a neurogenic tumor that arises from Schwann cells. Malignant schwannoma (MSh) is an aggressive cancer comprising 2% of all sarcomas. Information on the proper management of these tumors is limited. Four databases w...

(This article belongs to the Section Oncology)
  • Systematic Review
  • Open Access
1 Citations
4,141 Views
12 Pages

Predictors of Growth of Vestibular Schwannoma After Gamma Knife Treatment: A Systematic Review

  • Cheng Yang,
  • Daniel Alvarado,
  • Pawan Kishore Ravindran,
  • Max E. Keizer,
  • Koos Hovinga,
  • Martinus P. G. Broen,
  • Danielle Eekers,
  • Inge Compter,
  • Henricus P. M. Kunst and
  • Yasin Temel

14 June 2025

Background: GKRS shows a high success rate in controlling growth of vestibular schwannoma, but a small number of tumors still grow after treatment. However, only a few studies have investigated the predictive factors of this growth. Objective: Here,...

(This article belongs to the Section Cancer Therapy)
  • Case Report
  • Open Access
505 Views
8 Pages

Intra-Axial Cerebral Schwannoma in a Child: A Case Report

  • Adam M. Abdallah,
  • Atef F. Hulliel,
  • Bayan Maraqa and
  • Mouness Obeidat

Background: Primary intra-axial cerebral schwannomas are exceptionally rare benign tumors that arise within the brain parenchyma without any association with cranial nerves. Their nonspecific clinical and radiological features frequently mimic high-g...

(This article belongs to the Section Brain Tumor and Brain Injury)
  • Feature Paper
  • Article
  • Open Access
17 Citations
5,418 Views
9 Pages

10 January 2022

(1) Background: Schwannomas of the vestibulocochlear nerve are benign, slow-growing tumors, arising from the Schwann cells. When they originate from neural elements within the vestibule or cochlea, they are defined as intralabyrinthine schwannomas (I...

(This article belongs to the Special Issue Advances in Cochlear Implantation)
  • Case Report
  • Open Access
3,725 Views
5 Pages

Clinicopathologic Features of Neuroblastoma-like Schwannoma: A Case Report of Unusual Morphologic Variant

  • Samira Mortazavi,
  • Kambiz Kamyab Hesari,
  • Atieh Khorsand and
  • Maryam Ardalan

9 December 2022

Neuroblastoma-like schwannoma is known as a rare unusual variant of schwannoma with difficulties of differential diagnosis with neuroblastoma, Ewing sarcoma/peripheral neuroectodermal tumor and other cutaneous small round cell tumors. Herein, we desc...

(This article belongs to the Special Issue Advances in Anatomy and Its History)
  • Case Report
  • Open Access
2 Citations
3,463 Views
9 Pages

A Case Report of Hemifacial Spasm Caused by Vestibular Schwannoma and Literature Review

  • Xiaomin Cai,
  • Yinda Tang,
  • Hua Zhao,
  • Zheng Chen,
  • Haopeng Wang,
  • Wanchun Zhu and
  • Shiting Li

5 October 2022

Background: Most cases of hemifacial spasm result from mechanical compression at the root exit zone of the facial nerve by vascular loops, and only a few cases are caused by vestibular schwannoma. Case presentation: We report a case of symptomatic he...

(This article belongs to the Section Neurosurgery and Neuroanatomy)
  • Article
  • Open Access
1 Citations
1,318 Views
18 Pages

Fimepinostat Promotes Apoptosis and Decreases Cytokine Secretion in NF2-Related Human Schwannoma Cells

  • Anna Nagel,
  • Ethan W. Hass,
  • Hollie Hayes,
  • Lenna Huelbes,
  • Sofia Oliveira,
  • Haley M. Hardin,
  • Mikhail Marasigan,
  • Eric Nisenbaum,
  • Carly Misztal and
  • Cristina Fernandez-Valle
  • + 5 authors

There is no approved drug therapy for schwannomas associated with NF2-related schwannomatosis (NF2-SWN). Neither life-saving surgical resection or radiation are curative and can compound the debilitating neurological effects of the schwannomas. We pr...

(This article belongs to the Special Issue Neurofibromatosis Type 1 and NF2-Related Schwannomatosis: Advances from Basic Research to Current Therapies)
  • Article
  • Open Access
2,343 Views
18 Pages

Multidisciplinary Management of an Atypical Gigantic Sciatic Nerve Schwannoma: Case Presentation and Systematic Review

  • Octavian-Mihai Sirbu,
  • Mihai-Stelian Moreanu,
  • Mark-Edward Pogarasteanu,
  • Andreea Plesa,
  • Mihaela Iordache,
  • Teofil Mures,
  • Anca Maria Sirbu,
  • Marius Moga and
  • Marian Mitrica

28 September 2025

Background: Sciatic nerve schwannomas are rare benign tumors that can develop along the nerve’s course, from the pelvis to the thigh. Giant schwannomas, defined as those exceeding 5 cm, are particularly rare and may alter the tumor’s anat...

  • Review
  • Open Access
13 Citations
5,536 Views
20 Pages

Understanding the Molecular Mechanism of Vestibular Schwannoma for Hearing Preservation Surgery: Otologists’ Perspective from Bedside to Bench

  • Makoto Hosoya,
  • Takeshi Wakabayashi,
  • Koichiro Wasano,
  • Takanori Nishiyama,
  • Nobuyoshi Tsuzuki and
  • Naoki Oishi

Vestibular schwannoma is a clinically benign schwannoma that arises from the vestibulocochlear nerve that causes sensorineural hearing loss. This tumor is clinically and oncologically regarded as a benign tumor as it does not metastasize or invade su...

(This article belongs to the Special Issue Advances in Diagnostics of Otology and Neurotology)
  • Case Report
  • Open Access
1 Citations
1,119 Views
6 Pages

Synchronous Cervical Sympathetic Chain Schwannoma, Parathyroid Adenoma and Hypofunctional Nodular Goiter—A Case Report and Literature Review

  • Flaviu Muresan,
  • Alexandrina-Manuela Muresan,
  • Gabriel-Emil Petre,
  • Iacob Domsa,
  • Vasile Ovidiu Fabian and
  • Olga Hilda Orasan

Simultaneously diagnosing cervical sympathetic chain schwannoma, nodular goiter and parathyroid adenoma is a very rare event during clinical practice. We had the opportunity to find this unusual association on a female patient. While nodular goiter a...

  • Review
  • Open Access
98 Citations
23,853 Views
12 Pages

Neurofibromatosis Type 2 (NF2) and the Implications for Vestibular Schwannoma and Meningioma Pathogenesis

  • Suha Bachir,
  • Sanjit Shah,
  • Scott Shapiro,
  • Abigail Koehler,
  • Abdelkader Mahammedi,
  • Ravi N. Samy,
  • Mario Zuccarello,
  • Elizabeth Schorry and
  • Soma Sengupta

Patients diagnosed with neurofibromatosis type 2 (NF2) are extremely likely to develop meningiomas, in addition to vestibular schwannomas. Meningiomas are a common primary brain tumor; many NF2 patients suffer from multiple meningiomas. In NF2, patie...

(This article belongs to the Section Molecular Neurobiology)
  • Review
  • Open Access
10 Citations
3,894 Views
12 Pages

Thyroid-Bed Schwannoma Mimicking a Thyroid Neoplasm: A Challenging Diagnosis: Report of a Case and Literature Review

  • Claudio Gambardella,
  • Ludovico Docimo,
  • Giancarlo Candela,
  • Giovanni Cozzolino,
  • Federico Mongardini,
  • Francesca Serilli,
  • Giusiana Nesta,
  • Marcello Filograna Pignatelli,
  • Sonia Ferrandes and
  • Giovanni Docimo
  • + 1 author

24 September 2022

Background: Schwannomas, also called neurinomas, are rare benign tumors of the neural cells that can develop from the sheaths of nervous structures of several districts, although the most frequent sites are the cranial nerves (25%–45%). Rarely,...

(This article belongs to the Section Oncology)
  • Article
  • Open Access
2 Citations
1,863 Views
20 Pages

Identification of Follow-Up Markers for Rehabilitation Management in Patients with Vestibular Schwannoma

  • Frédéric Xavier,
  • Emmanuelle Chouin,
  • Brahim Tighilet,
  • Jean-Pierre Lavieille and
  • Christian Chabbert

13 September 2023

This study delves into the absence of prognostic or predictive markers to guide rehabilitation in patients afflicted with vestibular schwannomas. The objective is to analyze the reweighting of subjective and instrumental indicators following surgery,...

(This article belongs to the Special Issue Molecular and Cellular Mechanisms in Vestibular Disorders)
  • Case Report
  • Open Access
2 Citations
1,876 Views
11 Pages

7 June 2024

Preservation of function is an important goal during surgical management of cochleovestibular schwannomas. We here demonstrate the relief of vertigo and the preservation of function of all five vestibular receptors after removal of an intracochlear s...

(This article belongs to the Special Issue Current Trends in the Management of Vestibular Schwannoma)
  • Article
  • Open Access
1 Citations
1,182 Views
19 Pages

Immunohistopathology of Cochleovestibular Schwannoma in Human Temporal Bone Specimens

  • Jennifer T. O’Malley,
  • Anat O. Stemmer-Rachamimov,
  • Sebahattin Cureoglu,
  • Michael J. McKenna,
  • D. Bradley Welling and
  • Alicia M. Quesnel

3 November 2025

The aim of this study was to investigate the pathology of hearing loss caused by cochleo-vestibular schwannoma. Surgical specimens have demonstrated that a tumor may displace normal nerve fibers of the cochlear nerve to one side (pushing pattern) or...

(This article belongs to the Special Issue Pathophysiology of Hearing Loss)
  • Review
  • Open Access
17 Citations
16,591 Views
14 Pages

The Recent Management of Vestibular Schwannoma Radiotherapy: A Narrative Review of the Literature

  • Lucie Brun,
  • Thierry Mom,
  • Florent Guillemin,
  • Mathilde Puechmaille,
  • Toufic Khalil and
  • Julian Biau

11 March 2024

Background: Radiotherapy (RT) plays an important role in the therapeutic management of vestibular schwannoma (VS). Fractionated stereotactic radiotherapy (FSRT) or radiosurgery (SRS) are the two modalities available. The purpose of this article is to...

(This article belongs to the Section Otolaryngology)
  • Case Report
  • Open Access
1 Citations
1,098 Views
11 Pages

Diagnostic Pitfall in the Carotid Space: Accessory Nerve Schwannoma Simulating Cystic Metastasis—A Case Report

  • Roberts Tumelkans,
  • Elza Rate,
  • Madara Mikijanska,
  • Can Özütemiz,
  • Oksana Mahmajeva and
  • Arturs Balodis

27 February 2026

Objectives: The aim of this case report is to highlight the diagnostic challenges of carotid space masses, share clinical experience, and educate clinicians by presenting a case of a rare disease. Introduction: Accessory nerve schwannomas are rare, b...

(This article belongs to the Special Issue Advanced Diagnostics in Head and Neck Oncology)
  • Case Report
  • Open Access
4 Citations
3,798 Views
7 Pages

20 February 2022

Although radiologic methods confirm the diagnosis of patients with large vestibular schwannomas, these methods usually indicate only the size of the tumor and its possible nerve compression. Electrodiagnostic methods can reveal the functional state o...

(This article belongs to the Special Issue Evidence-Based Diagnosis and Management of Facial Nerve Disorders)
  • Article
  • Open Access
19 Citations
3,089 Views
11 Pages

Sex Differences in Vestibular Schwannoma

  • Kathrin Machetanz,
  • Sophie S. Wang,
  • Linda Oberle,
  • Marcos Tatagiba and
  • Georgios Naros

1 September 2023

Vestibular schwannoma (VS) are equally common in men and woman. A number of epidemiological studies have reported on sex-specific aspects of incidence, tumor size, tinnitus and hearing loss. However, data on sex-specific, pre- and post-surgically qua...

(This article belongs to the Section Cancer Survivorship and Quality of Life)
  • Article
  • Open Access
14 Citations
5,880 Views
11 Pages

Do Tumour Size, Type and Localisation Affect Resection Rate in Patients with Spinal Schwannoma?

  • Ahmet Parlak,
  • Marvin Darkwah Oppong,
  • Ramazan Jabbarli,
  • Oliver Gembruch,
  • Philipp Dammann,
  • Karsten Wrede,
  • Laurèl Rauschenbach,
  • Ulrich Sure and
  • Neriman Özkan

1 March 2022

Background and Objectives: Spinal schwannomas are benign tumours that can present with various symptoms such as pain, radiculopathy and neurological deficit. Gross total resection (GTR) is of key importance for local recurrence. The aim of this study...

(This article belongs to the Section Surgery)
  • Article
  • Open Access
15 Citations
3,514 Views
15 Pages

Macrophage and Lymphocyte Infiltration Is Associated with Volumetric Tumor Size but Not with Volumetric Growth in the Tübingen Schwannoma Cohort

  • Vítor Moura Gonçalves,
  • Elisa-Maria Suhm,
  • Vanessa Ries,
  • Marco Skardelly,
  • Ghazaleh Tabatabai,
  • Marcos Tatagiba,
  • Jens Schittenhelm and
  • Felix Behling

26 January 2021

Most patients with vestibular schwannomas can be cured with microsurgical resection, or tumor growth can be stabilized by radiotherapy in certain cases. Recurrence is rare but usually difficult to treat. Treatment alternatives to local therapies are...

(This article belongs to the Special Issue Schwannomas – So-Called Benign Nervous System Tumors)
  • Study Protocol
  • Open Access
799 Views
10 Pages

Study Protocol: Psychometric Testing of the German Vestibular Schwannoma Quality of Life Index—A Multicenter Study on Quality of Life and Patient-Centered Care in Vestibular Schwannoma

  • Mareike Rutenkröger,
  • Lasse Dührsen,
  • Maximilian Scheer,
  • Sandro M. Krieg,
  • Jannik Walter,
  • Andrea Baehr,
  • Bastian Baselt,
  • Alexander Huber and
  • Isabelle Scholl

Vestibular schwannomas (VSs) are benign tumors of the vestibulocochlear nerve that often cause significant neurological and functional impairment, affecting patients’ overall quality of life (QoL). While clinical assessments have traditionally...

(This article belongs to the Section Hearing)
  • Article
  • Open Access
2 Citations
2,433 Views
9 Pages

Which Epidemiological Characteristics Drive Decision Making in the Management of Patients with Vestibular Schwannoma?

  • Zdeněk Fík,
  • Aleš Vlasák,
  • Eduard Zvěřina,
  • Jaroslav Sýba,
  • Jan Lazák,
  • Lenka Peterková,
  • Vladimír Koucký and
  • Jan Betka

The incidence of sporadic vestibular schwannoma has significantly increased over the past few decades. However, there is no method currently available to accurately predict the risk of subsequent tumor growth. The difference in the management of five...

(This article belongs to the Special Issue Head and Neck Tumors 2.0)
  • Data Descriptor
  • Open Access
2 Citations
3,271 Views
10 Pages

Proteomic Shotgun and Targeted Mass Spectrometric Datasets of Cerebrospinal Fluid (Liquor) Derived from Patients with Vestibular Schwannoma

  • Svetlana Novikova,
  • Natalia Soloveva,
  • Tatiana Farafonova,
  • Olga Tikhonova,
  • Vadim Shimansky,
  • Ivan Kugushev and
  • Victor Zgoda

6 April 2023

Vestibular schwannomas are relatively rare intracranial tumors compared to other brain tumors. Data on the molecular features, especially on schwannoma proteome, are scarce. The 41 cerebrospinal fluid (liquor) samples were obtained during the surgica...

(This article belongs to the Section Computational Biology, Bioinformatics, and Biomedical Data Science)
  • Article
  • Open Access
12 Citations
3,471 Views
8 Pages

16 September 2021

Background: The combination of intralabyrinthine schwannoma (ILS) removal and cochlear implantation is the standard of care after surgical resection for audiological rehabilitation. Intracochlear ILS is not only the most frequent tumor in this group...

(This article belongs to the Section Sensory and Motor Neuroscience)
  • Review
  • Open Access
2 Citations
4,723 Views
9 Pages

Hearing Aid in Vestibular-Schwannoma-Related Hearing Loss: A Review

  • Valerio Maria Di Pasquale Fiasca,
  • Flavia Sorrentino,
  • Martina Conti,
  • Giulia De Lucia,
  • Patrizia Trevisi,
  • Cosimo de Filippis,
  • Elisabetta Zanoletti and
  • Davide Brotto

8 August 2023

(1) Background: Several types of hearing aids are available for the rehabilitation of vestibular-schwannoma (VS)-related hearing loss. There is a lack of recently published papers regarding this theme. The aim of the present work is to organize curre...

(This article belongs to the Special Issue Hearing and Balance in Acoustic Neuroma)

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