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Diagnostics
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Advances in Dental Diagnostics
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Advances in Dental Diagnostics

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Clinical Diagnosis and Prognosis".

Deadline for manuscript submissions: 31 December 2025 | Viewed by 1100

Special Issue Editors

Dr. Dirk Ziebolz

E-Mail Website
Guest Editor
Department of Cariology, Endodontology and Periodontology, University of Leipzig, Liebigstraße 12, 04103 Leipzig, Germany
Interests: oral health medicine; dental healthcare research; special care dentistry; interdisciplinary collaboration; oral and systemic disease interaction; oral health-related quality of life
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Margherita Fontana

E-Mail Website
Guest Editor
Department of Cariology, Restorative Sciences and Endodontics, University of Michigan School of Dentistry, 1011 North University, Ann Arbor, MI 48109, USA
Interests: endodontics

Special Issue Information

Dear Colleagues,

Diagnostics is a key discipline in dentistry which focuses on detecting, classifying, assessing, and monitoring hard tissue defects, e.g., caries or developmental dental defects, dental restorations, periodontitis, traumatized teeth, malocclusion, and other pathologies in the oral and maxillofacial region. The spectrum of diagnostic methods is broad and includes clinical examination procedures, dental radiography, optical devices, 3D scanners, and histological procedures. Furthermore, AI algorithms may automate diagnostic procedures or potentially enhance diagnostic performance. When considering the importance of diagnostics as well as existing knowledge gaps, this Special Issue offers the opportunity for clinicians, practitioners, epidemiologists, and researchers to present their latest findings in this area of interest. Herewith, I invite the scientific community to submit original manuscripts addressing the proposed topics.

The submission deadline is 31 December 2025. You may send your manuscript at any point from now until the deadline.

I look forward to welcoming your contributions to this Special Issue.

Dr. Dirk Ziebolz
Prof. Dr. Margherita Fontana
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • diagnosis
  • diagnostic imaging
  • artificial intelligence
  • caries
  • periodontitis
  • stomatognathic diseases

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

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21 pages, 1769 KiB  
Article
Evaluation of the Proximity of the Maxillary Teeth Root Apices to the Maxillary Sinus Floor in Romanian Subjects: A Cone-Beam Computed Tomography Study
by Vlad Ionuţ Iliescu, Vanda Roxana Nimigean, Cristina Teodora Preoteasa, Lavinia Georgescu and Victor Nimigean
Diagnostics 2025, 15(14), 1741; https://doi.org/10.3390/diagnostics15141741 - 9 Jul 2025
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Abstract
Background/Objectives: Among the paranasal sinuses, the maxillary antrum holds unique clinical relevance due to its proximity to the alveolar process of the maxilla, which houses the teeth. This study aimed to evaluate the position of the root apices of the maxillary canines [...] Read more.
Background/Objectives: Among the paranasal sinuses, the maxillary antrum holds unique clinical relevance due to its proximity to the alveolar process of the maxilla, which houses the teeth. This study aimed to evaluate the position of the root apices of the maxillary canines and posterior teeth relative to the maxillary sinus floor in Romanian subjects. Methods: Data for the study were retrospectively obtained from cone-beam computed tomography (CBCT) scans. The evaluation considered the pattern of proximity to the sinus floor for each tooth type, comparisons of the sinus relationships of teeth within the same dental hemiarch, as well as those of homologous teeth, and variation in root-to-sinus distance in relation to sex and age. Nonparametric tests were used for statistical analysis, and multiple comparisons were performed using Bonferroni post hoc correction. Results: The study included 70 individuals aged 20 to 60 years. The distance to the sinus floor decreased progressively from the first premolar to the second molar, with median values of 3.68 mm (first premolar), 1.45 mm (second premolar), 0.50 mm (first molar), and 0.34 mm (second molar) (p < 0.01). Stronger correlations were observed between adjacent teeth than between non-adjacent ones. The distances to the sinus floor were greater on the right side compared to the left; however, these differences were not statistically significant (p > 0.05 for all teeth). Concordance between left and right dental hemiarches regarding the closest tooth to the sinus floor was found in 70% of cases (n = 49), most frequently involving the second molars (n = 38; 54.3%). On average, the distance from the sinus floor was smaller in males compared to females, with statistically significant differences observed only for the second molar. Increased age was associated with a greater distance to the sinus floor. Conclusions: Of all the teeth investigated, the second molar showed the highest combined prevalence of penetrating and tangential relationships with the maxillary sinus. At the dental hemiarch level, the second molar was most frequently the closest tooth to the sinus floor, and in the majority of cases, at least one posterior tooth was located within 0.3 mm. Accurate preoperative assessment of tooth position relative to the sinus floor is essential when performing non-surgical or surgical root canal therapy and extractions of maxillary molars and premolars. CBCT provides essential three-dimensional imaging that improves diagnostic precision and supports safer treatment planning for procedures involving the posterior maxilla. Full article
(This article belongs to the Special Issue Advances in Dental Diagnostics)
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16 pages, 4492 KiB  
Case Report
Lip Schwannoma—A Rare Presentation in a Pediatric Patient: Case Report and a Literature Review
by Cinzia Casu, Mara Pinna, Andrea Butera, Carolina Maiorani, Girolamo Campisi, Clara Gerosa, Antonella Caiazzo, Andrea Scribante and Germano Orrù
Diagnostics 2025, 15(14), 1825; https://doi.org/10.3390/diagnostics15141825 - 20 Jul 2025
Viewed by 222
Abstract
Background/Objectives: Schwannoma is a rare tumor, typical in young adults, originating from the myelin sheath that surrounds Schwann cells. It can occur in any part of the Peripheral Nervous System (PNS). It develops in the head and neck region in 25–48% of [...] Read more.
Background/Objectives: Schwannoma is a rare tumor, typical in young adults, originating from the myelin sheath that surrounds Schwann cells. It can occur in any part of the Peripheral Nervous System (PNS). It develops in the head and neck region in 25–48% of cases, and the eighth pair of cranial nerves (vestibulocochlear nerves) are the most hit (vestibular schwannoma). Oral cavity involvement is exceedingly rare, accounting for about 1–2% of all cases. The most affected oral site is the tongue, especially its anterior third, while localization on the lip is one of the least common sites for the development of this lesion. Case Presentation: A lower lip schwannoma on a 17-year-old boy, present for about 7 years, was documented. Material and Methods: PubMed and Google Scholar were used as research engines; English scientific works published in the last 20 years (2005–2024) regarding oral cavity involvement, using the keywords “Schwannoma”, “Oral Schwannoma”, “Pediatric Oral Schwannoma”, and “Schwannoma of the lip”, were considered. Results: In total, 805 and 16,890 items were found on PubMed and Google Scholar search engines, respectively. After title, abstract, full text evaluation, and elimination of duplicates, 26 articles were included in the review process. Discussion: Clinically, oral schwannoma presents as an asymptomatic hard–elastic fluctuating mass, often misdiagnosed on the lip as a traumatic or inflammatory lesion (e.g., mucocele). Biopsy is mandatory, and histological examination reveals positivity to the neuronal marker S-100. Conclusions: Complete excision also prevents recurrence. Malignant transformation is extremely rare. Full article
(This article belongs to the Special Issue Advances in Dental Diagnostics)
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