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43 Results Found

  • Article
  • Open Access
2 Citations
1,323 Views
14 Pages

The Modification and Self-Lubricating Properties of CNTs-Enhanced PEEK Porous Composites Based on FDM

  • Zhuangya Zhang,
  • Baorun Yang,
  • Xiaoqiang Wang,
  • Ruijie Gu and
  • Mingde Duan

13 September 2025

Porous composites utilize their unique pore structures to effectively store and release lubricants, providing a fundamental mechanism for continuous lubrication in self-lubricating bearing cages. This study investigates carbon nanotube (CNT)-reinforc...

(This article belongs to the Special Issue Porous Nanomaterials: Preparation, Performance, and Practical Application)
  • Article
  • Open Access
22 Citations
7,874 Views
11 Pages

NaCl particles were added into Polyetheretherketone (PEEK) and its composites to produce porous PEEK-based materials by washing NaCl away after the high-temperature compression molding process. After that, an ionic liquid was added into the porous ma...

(This article belongs to the Special Issue Green Chemistry in Lubrication)
  • Article
  • Open Access
31 Citations
3,867 Views
16 Pages

9 December 2022

To address the problems of the difficult processing and internal microstructure disorder of porous bearing cages, Polyetheretherketone (PEEK) porous self-lubricating bearing cage material was prepared based on a fused deposition molding (FDM) process...

(This article belongs to the Special Issue 3D Printing Polymer: Processing and Fabrication)
  • Article
  • Open Access
28 Citations
4,189 Views
12 Pages

6 August 2020

Bone regeneration for replacing and repairing damaged and defective bones in the human body has attracted much attention over the last decade. In this research, highly porous polyetheretherketone (PEEK)/hydroxyapatite (HA) bionanocomposite scaffolds...

(This article belongs to the Special Issue 25th Anniversary of Molecules—Recent Advances in Materials Chemistry)
  • Article
  • Open Access
30 Citations
7,337 Views
12 Pages

11 October 2019

Incidents of lumbar degenerative diseases, such as spinal stenosis and degenerative spondylolisthesis, are increasing due to the aging population, and as a result, posterior lumbar interbody fusion (PLIF) is widely used. However, the interbody fusion...

  • Article
  • Open Access
87 Citations
12,577 Views
21 Pages

Characterization of New PEEK/HA Composites with 3D HA Network Fabricated by Extrusion Freeforming

  • Mohammad Vaezi,
  • Cameron Black,
  • David M. R. Gibbs,
  • Richard O. C. Oreffo,
  • Mark Brady,
  • Mohamed Moshrefi-Torbati and
  • Shoufeng Yang

Addition of bioactive materials such as calcium phosphates or Bioglass, and incorporation of porosity into polyetheretherketone (PEEK) has been identified as an effective approach to improve bone-implant interfaces and osseointegration of PEEK-based...

(This article belongs to the Special Issue Biomaterials and Bioprinting)
  • Article
  • Open Access
19 Citations
5,222 Views
12 Pages

Characterization of Porous Titanium-Hydroxyapatite Composite Biological Coating on Polyetheretherketone (PEEK) by Vacuum Plasma Spraying

  • Fengfan Hu,
  • Xiujuan Fan,
  • Feng Peng,
  • Xingchen Yan,
  • Jinbing Song,
  • Chunming Deng,
  • Min Liu,
  • Dechang Zeng and
  • Chengyun Ning

24 March 2022

Titanium powders and hydroxyapatite powders were used to fabricate the titanium and hydroxyapatite composite coating (Ti/Ti/HA) on the Polyetheretherketone (PEEK) by vacuum plasma spraying (VPS). The phase composition and morphology of the Ti/Ti/HA c...

(This article belongs to the Topic Multiple Application for Novel and Advanced Materials)
  • Article
  • Open Access
10 Citations
4,429 Views
12 Pages

Vertebral Endplate Concavity in Lateral Lumbar Interbody Fusion: Tapered 3D-Printed Porous Titanium Cage versus Squared PEEK Cage

  • Naoki Segi,
  • Hiroaki Nakashima,
  • Ryuichi Shinjo,
  • Yujiro Kagami,
  • Masaaki Machino,
  • Sadayuki Ito,
  • Jun Ouchida,
  • Kazuaki Morishita,
  • Ryotaro Oishi and
  • Shiro Imagama
  • + 1 author

15 February 2023

Background and Objectives: To prevent postoperative problems in extreme lateral interbody fusion (XLIF), it is critical that the vertebral endplate not be injured. Unintentional endplate injuries may depend on the cage. A novel porous titanium cage f...

(This article belongs to the Special Issue Minimally Invasive Spinal Treatment (MIST)—a New Concept in the Treatment of Spinal Diseases Ⅱ)
  • Article
  • Open Access
1 Citations
657 Views
29 Pages

Additive manufacturing enables the fabrication of porous polyetheretherketone (PEEK) structures with controlled architectures for biomedical applications. In particular, porous PEEK scaffolds have attracted significant attention due to their potentia...

(This article belongs to the Special Issue Processing, Mechanical Properties, and Manufacturing Techniques of Advanced Composite Materials)
  • Article
  • Open Access
25 Citations
5,153 Views
19 Pages

A Multi-Criteria Assessment Strategy for 3D Printed Porous Polyetheretherketone (PEEK) Patient-Specific Implants for Orbital Wall Reconstruction

  • Neha Sharma,
  • Dennis Welker,
  • Soheila Aghlmandi,
  • Michaela Maintz,
  • Hans-Florian Zeilhofer,
  • Philipp Honigmann,
  • Thomas Seifert and
  • Florian M. Thieringer

13 August 2021

Pure orbital blowout fractures occur within the confines of the internal orbital wall. Restoration of orbital form and volume is paramount to prevent functional and esthetic impairment. The anatomical peculiarity of the orbit has encouraged surgeons...

(This article belongs to the Special Issue 3D Printing and Virtual Surgical Planning in Oral and Maxillofacial Surgery)
  • Article
  • Open Access
208 Views
12 Pages

15 September 2026

Background: Cranioplasty using porous hydroxyapatite (PHA) implants is an established technique for cranial reconstruction due to its favorable osteointegration properties. However, the intrinsic fragility of PHA implants before complete osteointegra...

(This article belongs to the Special Issue Novel Approaches and Techniques in Neurosurgery)
  • Article
  • Open Access

Evaluation of Bone Regeneration by Sustained Release of Bone Morphogenetic Protein from Porous Polyetheretherketone

  • Yuka Shiotani,
  • Jun-ichiro Jo,
  • Sara Takasugi,
  • Takeryo Adachi,
  • Kenichirou Yasui,
  • Yoshiya Hashimoto and
  • Aki Nishiura

21 October 2026

Owing to its excellent mechanical properties and biocompatibility, polyetheretherketone (PEEK) is a promising biomaterial in dental and medical fields. However, PEEK lacks osteoconductive and osteoinductive properties for efficient bone regeneration....

(This article belongs to the Special Issue Application of Biomaterials in Human Diseases)
  • Article
  • Open Access
18 Citations
4,293 Views
18 Pages

Porous Titanium Surfaces to Control Bacteria Growth: Mechanical Properties and Sulfonated Polyetheretherketone Coatings as Antibiofouling Approaches

  • Ana M. Beltrán,
  • Ana Civantos,
  • Cristina Dominguez-Trujillo,
  • Rocío Moriche,
  • José A. Rodríguez-Ortiz,
  • Francisco García-Moreno,
  • Thomas J. Webster,
  • Paul H. Kamm,
  • Andrea Mesa Restrepo and
  • Yadir Torres

10 September 2019

Here, titanium porous substrates were fabricated by a space holder technique. The relationship between microstructural characteristics (pore equivalent diameter, mean free-path between pores, roughness and contact surface), mechanical properties (You...

(This article belongs to the Special Issue Powder Metallurgy of Titanium Alloys)
  • Article
  • Open Access
15 Citations
3,519 Views
13 Pages

19 April 2022

Polyetheretherketone (PEEK) is the only polymer material that can replace titanium implants in the field of orthopedics. This is because the mechanical properties of PEEK are similar to those of bone, and PEEK has natural radiolucency, chemical stabi...

(This article belongs to the Section Smart and Functional Polymers)
  • Abstract
  • Open Access
1,071 Views
1 Page

Polyetheretherketone (PEEK) is a promising biomedical material for orthopedic and dental applications due to its excellent mechanical properties, low immunogenicity, and X-ray transparency. However, it exhibits bio-inertness and limited osteoconducti...

(This article belongs to the Proceedings of The 3rd International Electronic Conference on Biomolecules)
  • Article
  • Open Access
9 Citations
5,819 Views
7 Pages

Single-Level Anterior Cervical Discectomy and Interbody Fusion: A Comparison between Porous Tantalum and Polyetheretherketone Cages

  • Edoardo Mazzucchi,
  • Giuseppe La Rocca,
  • Andrea Perna,
  • Fabrizio Pignotti,
  • Gianluca Galieri,
  • Vincenzo De Santis,
  • Pierluigi Rinaldi,
  • Francesco Ciro Tamburrelli and
  • Giovanni Sabatino

17 June 2022

Background: Anterior cervical discectomy and interbody fusion (ACDF) may be performed with different kinds of stand-alone cages. Tantalum and polyetheretherketone (PEEK) are two of the most commonly used materials in this procedure. Few comparisons b...

(This article belongs to the Section Methodology, Drug and Device Discovery)
  • Article
  • Open Access
31 Citations
6,021 Views
23 Pages

Polyether-Ether-Ketone (PEEK) and Its 3D-Printed Quantitate Assessment in Cranial Reconstruction

  • Khaja Moiduddin,
  • Syed Hammad Mian,
  • Sherif Mohammed Elseufy,
  • Hisham Alkhalefah,
  • Sundar Ramalingam and
  • Abdul Sayeed

Three-dimensional (3D) printing, medical imaging, and implant design have all advanced significantly in recent years, and these developments may change how modern craniomaxillofacial surgeons use patient data to create tailored treatments. Polyether-...

(This article belongs to the Special Issue Design, Synthesis and Medical Application of Porous Biomaterials)
  • Article
  • Open Access
5 Citations
2,901 Views
14 Pages

8 May 2024

There has been a recent uptake in the use of polyether-ether-ketone (PEEK), which is an organic thermoplastic polymer, in the manufacturing of various medical devices, implants, and equipment. Finding the best time and procedure for PEEK after sulfon...

(This article belongs to the Section Applied Dentistry and Oral Sciences)
  • Article
  • Open Access
893 Views
16 Pages

Herein, we report a method to additively manufacture carbon fiber-reinforced siliconized silicon carbide composites. The process involves the pyrolysis of a 3D-printed carbon fiber-reinforced poly-ether-ether-ketone (PEEK) composite to produce a poro...

(This article belongs to the Special Issue Ceramic Materials for Industrial Decarbonization)
  • Article
  • Open Access
21 Citations
4,136 Views
17 Pages

Immunomodulatory Properties and Osteogenic Activity of Polyetheretherketone Coated with Titanate Nanonetwork Structures

  • Yuanyuan Yang,
  • Honghao Zhang,
  • Satoshi Komasa,
  • Tetsuji Kusumoto,
  • Shinsuke Kuwamoto,
  • Tohru Okunishi,
  • Yasuyuki Kobayashi,
  • Yoshiya Hashimoto,
  • Tohru Sekino and
  • Joji Okazaki

Polyetheretherketone (PEEK) is a potential substitute for conventional metallic biomedical implants owing to its superior mechanical and chemical properties, as well as biocompatibility. However, its inherent bio-inertness and poor osseointegration l...

(This article belongs to the Topic Nanoarchitectonics with Molecular and Materials Science: Functional Materials for Energy, Environment, Bio and Others)
  • Article
  • Open Access
14 Citations
3,344 Views
19 Pages

Evaluation of the Grafting Efficacy of Active Biomolecules of Phosphatidylcholine and Type I Collagen on Polyether Ether Ketone: In Vitro and In Vivo

  • Jian-Chih Chen,
  • Chih-Hua Chen,
  • Kai-Chi Chang,
  • Shih-Ming Liu,
  • Chia-Ling Ko,
  • Chi-Jen Shih,
  • Ying-Sui Sun and
  • Wen-Cheng Chen

24 June 2021

Biomolecule grafting on polyether ether ketone (PEEK) was used to improve cell affinity caused by surface inertness. This study demonstrated the sequence-polished (P) and sulfonated (SA) PEEK modification to make a 3D structure, active biomolecule gr...

(This article belongs to the Special Issue Nanomaterials Template for Organic or Composite Polymers in Biomedical Application)
  • Review
  • Open Access
150 Citations
14,176 Views
48 Pages

29 November 2020

In this article, recent advances in the development, preparation, biocompatibility and mechanical properties of polyetheretherketone (PEEK) and its composites for hard and soft tissue engineering are reviewed. PEEK has been widely employed for fabric...

(This article belongs to the Special Issue Biomedical Polymer Materials II)
  • Article
  • Open Access
24 Citations
3,603 Views
16 Pages

PEEK and Hyaluronan-Based 3D Printed Structures: Promising Combination to Improve Bone Regeneration

  • Letizia Ferroni,
  • Ugo D’Amora,
  • Sara Leo,
  • Elena Tremoli,
  • Maria Grazia Raucci,
  • Alfredo Ronca,
  • Luigi Ambrosio and
  • Barbara Zavan

9 December 2022

Hybrid bone substitute made up of a 3D printed polyetheretherketone (PEEK) scaffold coated with methacrylated hyaluronic acid (MeHA)-hydroxyapatite (HAp) hydrogel is the objective of the present work. Development and characterization of the scaffold...

(This article belongs to the Special Issue Polymer Scaffolds for Biomedical Applications III)
  • Article
  • Open Access
1,340 Views
17 Pages

31 July 2025

Porosity and roughened surfaces of implant materials have been shown to lead to improved cellular attachment and enhanced osseointegration. These topography changes in the surface also aid in the mechanical interlocking of the material to the bone. P...

(This article belongs to the Special Issue Feature Papers in 'Surface Sciences and Technology' Section, 3rd Edition)
  • Article
  • Open Access
8 Citations
3,448 Views
12 Pages

17 February 2023

Porous titanium interbody scaffolds are growing in popularity due to their appealing advantages for bone ingrowth. This study aimed to investigate the biomechanical effects of scaffold materials in both normal and osteoporotic lumbar spines using a f...

(This article belongs to the Topic Advanced Manufacturing and Surface Technology)
  • Article
  • Open Access
35 Citations
4,604 Views
14 Pages

Polyether-ether-ketone (peek) is one of the most common materials used for load-bearing orthopedic devices owing to its radiolucency and favorable mechanical properties. However, current smooth-surfaced peek implants can lead to fibrous capsule forma...

(This article belongs to the Section Materials Science)
  • Review
  • Open Access
85 Citations
10,590 Views
19 Pages

Surface Treatments of PEEK for Osseointegration to Bone

  • Jay R. Dondani,
  • Janaki Iyer and
  • Simon D. Tran

2 March 2023

Polymers, in general, and Poly (Ether-Ether-Ketone) (PEEK) have emerged as potential alternatives to conventional osseous implant biomaterials. Due to its distinct advantages over metallic implants, PEEK has been gaining increasing attention as a pri...

(This article belongs to the Special Issue Novel Materials for Biomedical Applications)
  • Review
  • Open Access
3 Citations
4,714 Views
14 Pages

Facial Contouring in Orthognathic Surgery: The Role of Facial Implants

  • Gabriel Conceição Brito,
  • Márcio de Moraes,
  • Leonardo Faverani and
  • Sergio Olate

Orthognathic surgery restores functional balance and facial esthetics in patients with dentofacial deformities. The use of adjunctive facial implants—made from materials such as porous polyethylene, titanium, or polyetheretherketone (PEEK)&mdas...

(This article belongs to the Special Issue Innovation in Oral- and Cranio-Maxillofacial Reconstruction)
  • Feature Paper
  • Article
  • Open Access
21 Citations
2,728 Views
14 Pages

5 September 2023

In the present study, the antimicrobial peptide nisin was successfully conjugated onto the surface of sulfonated polyetheretherketone (SPEEK), which was decorated with graphene oxide (GO) to investigate its biofilm resistance and antibacterial proper...

(This article belongs to the Special Issue Development and Biomedical Application of Antibacterial Coatings)
  • Article
  • Open Access
4 Citations
1,274 Views
13 Pages

Engineering Self-Assembled PEEK Scaffolds with Marine-Derived Exosomes and Bacteria-Targeting Aptamers for Enhanced Antibacterial Functions

  • Chen Zhang,
  • Jinchao You,
  • Runyi Lin,
  • Yuansong Ye,
  • Chuchu Cheng,
  • Haopeng Wang,
  • Dejing Li,
  • Junxiang Wang and
  • Shan Chen

Repairing bone defects with implants is an important topic in the field of regenerative medicine, but bacterial infection presents a significant barrier in clinical practice. Therefore, bone implants with antibacterial functionality are currently in...

(This article belongs to the Section Antibacterial Biomaterials)
  • Article
  • Open Access
23 Citations
5,438 Views
26 Pages

13 November 2020

Polyetheretherketone (PEEK) has emerged as the material of choice for spinal fusion devices, replacing conventional materials such as titanium and its alloys due to its ability to easily overcome a lot of the limitations of traditional metallic bioma...

(This article belongs to the Special Issue Physical Vapor Deposited Biomedical Coatings)
  • Article
  • Open Access
20 Citations
5,180 Views
10 Pages

Transforaminal Fusion Using Physiologically Integrated Titanium Cages with a Novel Design in Patients with Degenerative Spinal Disorders: A Pilot Study

  • Renat Nurmukhametov,
  • Medet Dosanov,
  • Manuel De Jesus Encarnacion,
  • Rossi Barrientos,
  • Yasser Matos,
  • Alexander Ivanovich Alyokhin,
  • Ismael Peralta Baez,
  • Ibrahim Efecan Efe,
  • Manuela Restrepo and
  • Nicola Montemurro
  • + 2 authors

30 June 2022

More contemporary options have been presented in the last few years as surgical methods and materials have improved in patients with degenerative spine illnesses. The use of biologically integrated titanium cages of a unique design based on computer...

  • Article
  • Open Access
6 Citations
2,833 Views
16 Pages

3D Printing for Customized Bone Reconstruction in Spheno-Orbital Meningiomas: A Systematic Literature Review and Institutional Experience

  • Simona Serioli,
  • Alberto Pietrantoni,
  • Alberto Benato,
  • Marco Galeazzi,
  • Amedeo Piazza,
  • Liverana Lauretti,
  • Pier Paolo Mattogno,
  • Alessandro Olivi,
  • Marco Maria Fontanella and
  • Francesco Doglietto

6 July 2024

Background: The treatment of spheno-orbital meningiomas (SOMs) requires extensive bone resections, creating significant defects in a complex geometrical space. Bone reconstruction represents a fundamental step that optimizes long-term aesthetic and f...

(This article belongs to the Special Issue State of the Art—Treatment of Skull Base Diseases (Second Edition))
  • Article
  • Open Access
6 Citations
3,697 Views
17 Pages

Comprehensive Biological Evaluation of Biomaterials Used in Spinal and Orthopedic Surgery

  • Piotr Komorowski,
  • Małgorzata Siatkowska,
  • Marta Kamińska,
  • Witold Jakubowski,
  • Marta Walczyńska,
  • Magdalena Walkowiak-Przybyło,
  • Witold Szymański,
  • Katarzyna Piersa,
  • Patryk Wielowski and
  • Bogdan Walkowiak
  • + 6 authors

26 October 2020

Biological acceptance is one of the most important aspects of a biomaterial and forms the basis for its clinical use. The aim of this study was a comprehensive biological evaluation (cytotoxicity test, bacterial colonization test, blood platelets adh...

(This article belongs to the Section Biomaterials)
  • Article
  • Open Access
5 Citations
2,798 Views
13 Pages

Biomimetic Layered Hydrogel Coating for Enhanced Lubrication and Load-Bearing Capacity

  • Xuxu Hu,
  • Yu Zhao,
  • Shuai Cheng,
  • Jinming Zhen,
  • Zhengfeng Jia and
  • Ran Zhang

23 September 2024

Biomimetic hydrogel lubrication coatings with high wettability and low friction show great promise in tissue engineering, wound dressing, drug delivery, and intelligent sensing. Inspired by the hierarchical structure of natural cartilage, a layered h...

  • Article
  • Open Access
14 Citations
2,752 Views
17 Pages

27 October 2022

Herein, we report a new approach for the sulfonation of polyether ether ketone (PEEK) following a shorter path of reaction undertaken at 60 °C under ultrasonication. The application of this method enabled the reduction of the reaction time from s...

  • Article
  • Open Access
11 Citations
4,015 Views
13 Pages

Ultra-high-molecular-weight polyethylene (UHMWPE) components for orthopedic implants have historically been integrated into metal backings by direct-compression molding (DCM). However, metal backings are costly, stiffer than cortical bone, and may be...

(This article belongs to the Special Issue Advanced Technology for Implant Polymers in Orthopaedics, Spine, and Trauma)
  • Article
  • Open Access
26 Citations
6,305 Views
21 Pages

9 July 2022

Icing and ice accretion cause severe problems in different industrial sectors, e.g., in aircrafts, aviation traffic, ships, solar panels, and wind turbines. This can lead to enormous economic losses and serious safety issues. Surface engineering can...

(This article belongs to the Special Issue Toward Sustainable Multifunctional Coatings)
  • Article
  • Open Access
14 Citations
5,709 Views
16 Pages

Multi-Scale Digital Image Correlation Analysis of In Situ Deformation of Open-Cell Porous Ultra-High Molecular Weight Polyethylene Foam

  • Eugene S. Statnik,
  • Codrutza Dragu,
  • Cyril Besnard,
  • Alexander J.G. Lunt,
  • Alexey I. Salimon,
  • Aleksey Maksimkin and
  • Alexander M. Korsunsky

6 November 2020

Porous ultra-high molecular weight polyethylene (UHMWPE) is a high-performance bioinert polymer used in cranio-facial reconstructive surgery in procedures where relatively low mechanical stresses arise. As an alternative to much stiffer and more cost...

(This article belongs to the Special Issue High-Performance Polyethylene)
  • Feature Paper
  • Article
  • Open Access
5 Citations
4,492 Views
10 Pages

Development of a Freeze-Drying Stage for In-Situ µ-CT Measurements

  • Mathias Hilmer,
  • Sebastian Gruber and
  • Petra Foerst

18 July 2020

This paper shows the development of a freeze-drying stage for in-situ μ-CT measurements. The stage can operate in a temperature range of −40 °C up to 70 °C, and a pressure range from atmospheric pressure to 7 Pa at the sample holder....

(This article belongs to the Special Issue Modern Freeze Drying Design for More Efficient Processes)
  • Article
  • Open Access
47 Citations
9,503 Views
16 Pages

Evolution of Electrochemical Cell Designs for In-Situ and Operando 3D Characterization

  • Chun Tan,
  • Sohrab R. Daemi,
  • Oluwadamilola O. Taiwo,
  • Thomas M. M. Heenan,
  • Daniel J. L. Brett and
  • Paul R. Shearing

1 November 2018

Lithium-based rechargeable batteries such as lithium-ion (Li-ion), lithium-sulfur (Li-S), and lithium-air (Li-air) cells typically consist of heterogenous porous electrodes. In recent years, there has been growing interest in the use of in-situ and o...

(This article belongs to the Special Issue In-Situ X-Ray Tomographic Study of Materials)
  • Article
  • Open Access
32 Citations
7,415 Views
14 Pages

Endowing implants with antibacterial ability and osteogenic ability plays important roles in preventing post-operative bacterial contamination and facilitating integration between implants and osseous tissue, consequently reducing implant failure rat...

(This article belongs to the Special Issue Advanced Bioadhesive and Bioabhesive Coatings)
  • Review
  • Open Access
2 Citations
1,612 Views
16 Pages

Advancements in Individual Dental Implants: A State-of-the-Art Review of Materials and Technologies

  • Monika Lukomska-Szymanska,
  • Mateusz Radwanski,
  • Michal Leski,
  • Aftab Ahmed Khan and
  • Jukka P. Matinlinna

24 April 2026

Objective: This narrative review synthesizes current evidence on materials and manufacturing technologies for customized dental implants, highlighting their comparative advantages and limitations. Methods: A structured literature search (December 202...

(This article belongs to the Section Biomaterials)