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Proceedings, Volume 103, Issue 1

2024 IECBM 2024 - 91 articles

The 3rd International Electronic Conference on Biomolecules

Online | 23–25 April 2024

Volume Editor:
Vladimir N. Uversky, University of South Florida, USA

Cover Story: This volume presents a collection of accepted abstracts from the 3rd International Electronic Conference on Biomolecules held on 23–25 April 2024. This virtual conference offers biomolecular researchers and scientists a chance to interact, learn from each other, share ideas, solve problems, and suggest alternative solutions. The main topics and sessions of the conference are as follows: biomolecular structures and functions; molecular mechanisms in cellular processes; biomolecular interactions and networks; biomaterials design and characterization; biocatalysis and enzyme engineering; and bioinformatics and computational biology.
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Articles (91)

  • Abstract
  • Open Access
421 Views
2 Pages

Draft Transcriptomic Resources for the California Native Plant Trichostema lanatum from the Angeles National Forest

  • Savanah Senn,
  • Steven J. Carrell,
  • Bruce Nash,
  • Ray A. Enke,
  • Karen Barnard-Kubow,
  • Karu Smith,
  • Daila Melendez,
  • Mathew Kostoglou,
  • John Hsieh and
  • Gerald Presley
  • + 2 authors

This project established transcriptome and soil metagenomic resources for Trichostema lanatum [...]

  • Abstract
  • Open Access
718 Views
2 Pages

Pulegone is a natural biomolecule that may be found in essential oils from many medicinal and aromatic plants, especially those from the Lamiaceae family. It is known for its distinguished minty aroma and taste, and it has been studied for its potent...

  • Abstract
  • Open Access
1,813 Views
2 Pages

Antibacterial Effect of Cymbopogon citratus Essential Oil against Gram-Positive Bacterial Strains

  • Dicla Aline Semedo da Veiga,
  • Bernardina de Paixão Santos,
  • Francisco Sérgio da Silva Sousa,
  • Everton Vieira da Silva and
  • Sávio Benvindo Ferreira

Cymbopogon citratus, popularly known as “lemongrass”, is an herbaceous species originating from India, belonging to the Poaceae family, to which it is acclimatized in several typical regions of Brazil [...]

  • Abstract
  • Open Access
694 Views
2 Pages

Purine Stretches Are Avoided by Cancer Mutations

  • Aleksandr V. Vikhorev,
  • Ivan Savelev,
  • Oksana Polesskaya,
  • Michael M. Rempel,
  • Alexandre A. Vetcher and
  • Max Myakishev-Rempel

Purine stretches, sequences of adenine (A) and guanine (G) in DNA, play critical roles in binding regulatory protein factors and influence gene expression by affecting DNA folding. Both purines can exist in the enol-amine form (often referred to as t...

  • Abstract
  • Open Access
908 Views
2 Pages

Diabetes mellitus, a metabolic disorder, elevates blood sugar levels, resulting in complications affecting various bodily systems such as the nerves, eyes, kidneys, and other organs. The administration of oral antihyperglycemic medications can potent...

  • Abstract
  • Open Access
717 Views
2 Pages

Background: Over 90% of oral cancer deaths are due to metastases, facilitated by a mechanism, epithelial–mesenchymal transition (EMT), that demonstrates a mesenchyme-like phenotype of epithelial cells [...]

  • Abstract
  • Open Access
964 Views
2 Pages

Structural Diversity of Oligosaccharides Isolated from Milk of Various Cow Breeds

  • Desh Deepak A. P. Singh Chauhan,
  • Manisha Shukla,
  • Desh Deepak and
  • Sarita Chauhan

Cow milk oligosaccharides (CMOs) have garnered significant attention due to their association with enhanced infant immune system development, defence against pathogens, and anti-inflammatory properties [...]

  • Abstract
  • Open Access
871 Views
2 Pages

Molecular Structure Considerations for the Possibility of Sequence-Dependent DNA Resonances

  • Ivan Savelev,
  • Alexandre A. Vetcher,
  • Nelli Zyryanova,
  • Richard A. Miller and
  • Max Myakishev-Rempel

For years, the mechanisms of non-chemical and non-contact communication between cells and organisms have not been studied to the same extent as those associated with the chemical mediators [...]

  • Abstract
  • Open Access
660 Views
2 Pages

Abstract: Flavonoids are one of the largest classes of secondary metabolites that have been shown to be potent antimicrobials against a wide range of pathogenic organisms in vitro [...]

  • Abstract
  • Open Access
1 Citations
927 Views
2 Pages

Antibacterial Action of Lippia origanoides Essential Oil

  • Francisco Sérgio da Silva Sousa,
  • Dicla Aline Semedo da Veiga,
  • Bernardina De Paixão Santos,
  • Rafaelle Cavalcanti de Lira and
  • Sávio Benvindo Ferreira

Bacterial resistance to antibiotics makes infections increasingly difficult to fight. In this context, the antimicrobial capacity of Lippia origanoides proved to be a relevant alternative. The purpose of this review is to evaluate the antibacterial a...

  • Abstract
  • Open Access
672 Views
2 Pages

The Potentiate Production of Phycobiliprotein from Oscillatoria sp. for Its Application as a Food Coating Agent and Microbial Inhabitant

  • Nadia Sharif,
  • Uzma Nihar,
  • Neelma Munir,
  • Rakhshinda Sadiq,
  • Syed Ali Raza Shah and
  • Zainul Abideen

Phycobiliproteins (PBPs) are fluorescent proteins of numerous colors with several highly conserved structural and physicochemical characteristics [...]

  • Abstract
  • Open Access
862 Views
2 Pages

Protease-activated receptor 2 (PAR2) plays a pivotal role in activating pain and inflammation pathways in rheumatoid arthritis (RA), contributing to cartilage destruction, synovial inflammation, and heightened joint pain [...]

  • Abstract
  • Open Access
922 Views
2 Pages

Introduction: This research work is designed to identify biomolecules from Earthworm Coelomic Fluid (ECF) of Eudrilus Eugeniae (EE) that can inhibit cancer cellproliferation [...]

  • Abstract
  • Open Access
980 Views
2 Pages

Multilayer Immunohistochemical Analysis of Brain Tissue in Severe Traumatic Brain Injury

  • Chloe L. T. Kam,
  • Cengiz Guner,
  • Shumaila Hasan,
  • Christopher E. G. Uff and
  • Ping K. Yip

Severe traumatic brain injury (TBI) is a complex disease, and understanding its injury-induced cellular pathobiology is vital to predicting outcomes and providing effective treatment and precision healthcare [...]

  • Abstract
  • Open Access
822 Views
2 Pages

Anticancer Effects of the Potential BET Inhibitor CBL0137 on Breast Cancer Cells

  • Valeriia Popova,
  • Varvara Maksimova,
  • Evgeniya Lylova,
  • Anzhelika Bukina,
  • Marianna Yakubovskaya and
  • Kirill Kirsanov

Breast cancer (BC) is a complex disease driven by a combination of genetic mutations and epigenetic modifications. In particular, the overexpression of BET family proteins (BETs) has emerged as a key epigenetic aberration contributing to BC pathogene...

  • Abstract
  • Open Access
807 Views
2 Pages

Investigation of the Antibacterial Activity of Essential Oil from Cymbopogon citratus Leaves against Gram-Negative Bacteria

  • Bernardina de Paixão Santos,
  • Dicla Aline Semedo da Veiga,
  • Francisco Sérgio da Silva Sousa,
  • Everton Vieira da Silva and
  • Sávio Benvindo Ferreira

Gram-negative bacteria cause a multitude of infections in humans and, over time, many have developed resistance to conventional antibiotics, making available treatments less effective [...]

  • Abstract
  • Open Access
925 Views
1 Page

Introduction: Ciguatoxin (CTX) is a potent marine toxin known for its detrimental effects on the Central Nervous System (CNS), inducing symptoms of depression and neurological dysfunction. The nervous system’s synapses’ threshold for open...

  • Abstract
  • Open Access
1,112 Views
2 Pages

Malaria is one of the infectious illnesses causing a public health burden worldwide. Plasmodium vivax (P. vivax) is the most prevalent malaria parasite in Asia and Asia Pacific. P. vivax is resistant to sulfadoxine–pyrimethamine (SP) and mefloq...

  • Abstract
  • Open Access
1,239 Views
2 Pages

Human skin is constantly exposed to various endogenous and exogenous factors, including UV radiation and vitamin deficiency, which can influence the earlier appearance of visible wrinkles and decrease skin firmness and elasticity. This process is rel...

  • Abstract
  • Open Access
1,059 Views
2 Pages

Introduction: Diabetes, a global health issue, can cause diabetic nephropathy in one third of its sufferers. Recently, β-amyrin, a natural pentacyclic triterpene, has garnered interest for its potential to combat diabetes and treat chronic kidne...

  • Abstract
  • Open Access
697 Views
2 Pages

To pioneer an innovative in silico exploration of Zingiber officinalis for Rheumatoid Arthritis, employing virtual screening to discern the impact of its chemical constituents on the cyclo-oxygenase receptor [...]

  • Abstract
  • Open Access
1 Citations
1,684 Views
2 Pages

Starch–Polyphenol Interactions: Impact on Food Structure and Starch Digestibility

  • Javier Echave,
  • Sepidar Seyyedi-Mansour,
  • Pauline Donn,
  • Ana Olivia Serra Jorge,
  • Lucia Cassani,
  • Lillian Barros and
  • Miguel Angel Prieto

Starch, conformed by amylose and amylopectin, represents the major carbohydrate macromolecule consumed globally as a major component of staple foods. Phenolic compounds are ubiquitous secondary metabolites in plants with strong antioxidant capacities...

  • Abstract
  • Open Access
706 Views
2 Pages

Candia auris is a fungal pathogen that has emerged as a global threat in recent years due to its resistance to multiple antifungal drugs and its ability to cause invasive infections, especially in immunosuppressed patients [...]

  • Abstract
  • Open Access
1 Citations
1,536 Views
2 Pages

Phlorotannins as Bioactive Agents from Brown Algae: Chemical Characterization and Extraction Methods

  • Camila F. Secco Bastos,
  • Maria Carpena,
  • Franklin Chamorro,
  • Rafael Nogueira-Marques,
  • Aurora Silva,
  • Maria Fátima Barroso,
  • Marlene Santos and
  • Miguel A. Prieto

Marine organisms, especially brown seaweeds, have attracted a lot of attention worldwide because of their potential for use in treating a range of infectious and non-infectious diseases, being able to take part in the creation of medications and nutr...

  • Abstract
  • Open Access
881 Views
2 Pages

The gel of low-esterification pectin has no special requirements for soluble solids and is often used as a thickening agent, gelling agent and stabilizer in food. Pectin is difficult to digest and absorb when ingested by the human body. It is mainly...

  • Abstract
  • Open Access
840 Views
2 Pages

Studying the Inhibitory Activity of Novel Series Compounds for Parkinson’s Disease Using a Molecular Docking Method

  • Rania Kherachi,
  • Daoud Ismail,
  • Merzaka Mettai,
  • Ferdaous Hasni and
  • Melkemi Nadjib

After Alzheimer’s disease, Parkinson’s disease (PD) is the second most prevalent neurological illness. Clinically, it is defined by parkinsonism, which includes stiffness, bradykinesia, resting tremor, and postural instability. Pathologic...

  • Abstract
  • Open Access
697 Views
2 Pages

Adiposity: A Seed of Depression

  • Dhivya Selvaraj,
  • Pramod Kumar Pandey,
  • Tunjin Vashisth,
  • Sukanya Gangopadhyay,
  • Usha Bindal and
  • Kuldip Kumar

Introduction: Depression is a very common psychological problem observed all around the world. Though various treatment modalities are available for this mental illness, further research is warranted to find novel therapeutics. Recent speculations on...

  • Abstract
  • Open Access
638 Views
2 Pages

HIF-1α as a Potential Target for Pharmacologic Correction after Prenatal Hypoxia

  • Olena Gennadiivna Aliyeva,
  • Igor Fedorovich Belenichev and
  • Olena Olexandrivna Popazova

Chronic prenatal hypoxia (CPH) is one of the most common causes of neonatal mortality and postnatal disorders of the nervous system and the mental development of infants [...]

  • Abstract
  • Open Access
695 Views
2 Pages

Amperometric Determination of Serotonin Exocytosis in Human Platelets with BDD-on-Quartz MEA Devices

  • Rosalía González-Brito,
  • Pablo Montenegro,
  • Alicia Méndez,
  • Ramtin E. Shabgahi,
  • Alberto Pasquarelli and
  • Ricardo Borges

Amperometry is arguably the most widely used technique for studying the exocytosis of biological amines, allowing the study of the dynamics and kinetics of this cellular mechanism in real time [...]

  • Abstract
  • Open Access
916 Views
2 Pages

The intestinal microbiome is important for synthesising nutrients, breaking down polysaccharides, protecting against foreign microbes, and aiding immune system development by producing short-chain fatty acids (SCFAs). SCFAs are formed through the int...

  • Abstract
  • Open Access
666 Views
1 Page

The Role of the Charged Residues in the C-Gate of the Yeast Mitochondrial NAD+ Transporter Ndt1p

  • Daniela Valeria Miniero,
  • Magnus Monné,
  • Maria Antonietta Di Noia,
  • Luigi Palmieri and
  • Ferdinando Palmieri

The mitochondrial carrier family (MCF) consists of nuclear-encoded proteins which catalyze the transport of a wide variety of compounds across the mitochondrial inner membrane. These proteins present common structural features, which consist of three...

  • Abstract
  • Open Access
745 Views
2 Pages

After cardiovascular diseases, the leading cause of death all around the world is cancer. Rhobdomyosarcoma (RMS) is the cancer of soft tissues and it mostly occurs in children and in adults aged between 10 and 25 years. There are several therapeutic...

  • Abstract
  • Open Access
1,936 Views
2 Pages

Dermo-cosmetics are cosmetics combined with bioactive ingredients to impart therapeutic benefits on the skin and have made significant advances in recent decades [...]

  • Abstract
  • Open Access
1,185 Views
1 Page

Chandipura virus (CHPV) is a vesiculovirus that is a member of Rhabdviridae and is an encephalitic pathogen responsible for numerous epidemics in Central and Western India. The virus affects the brain and central nervous system mainly in children und...

  • Abstract
  • Open Access
1 Citations
1,291 Views
3 Pages

Osteoarthritis (OA) is the most common form of chronic joint disease characterized by the loss of cartilage as the primary site of the lesion [...]

  • Abstract
  • Open Access
1 Citations
776 Views
2 Pages

This study focuses on the comprehensive analysis of machine learning algorithms for the classification of breast cancer into benign and malignant categories using the Wisconsin breast cancer dataset [...]

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Proceedings - ISSN 2504-3900