The accurate and reliable acquisition of measurement information is very important for the stable operation of power systems, especially the operation status information of new energy stations. With the increasing proportion of new energy stations in...
Background: The parallel stent graft endovascular aortic repair (PGEVAR) technique is an off-the-shelf option used for elective complex abdominal aortic aneurysm repair with acceptable outcome results, as reported so far. The PGEVAR technique, using...
In resilience-based frameworks, optimizing the repair strategy and approaches is important for the recovery of the function of gas network systems (GNS) and water network systems (WNS). According to the resilience quantification results of GNS and WN...
This work offers a reliability framework for a five-subsystem hybrid series-parallel system representing smart factory monitoring infrastructure under heat and vibration stressors. A central programmable logic controller (1-out-of-1), pressure and te...
Thoracic endovascular aortic repair is established for complicated type B aortic dissection, but extension of disease toward the aortic arch and involvement of supra-aortic branches may require technically demanding, individualized solutions. We repo...
Background: Endovascular aortic aneurysm repair (EVAR) represents a valid treatment modality for ruptured abdominal aortic aneurysms (rAAAs). This study aimed to present rAAA outcomes treated by EVAR using the Endurant endograft. Methods: A single-ce...
This paper deals with an integrated and interconnected stochastic queuing-inventory system with a fresh item, a returned item, and a refurbished item. This system provides a multi-type service facility to an arriving multi-class customer through a de...
Neural-network computing has revolutionized the field of machine learning. The systolic-array architecture is a widely used architecture for neural-network computing acceleration that was adopted by Google in its Tensor Processing Unit (TPU). To ensu...
This paper deals with a preventive maintenance strategy optimization correlated to production for a manufacturing system made by several parallel machines under lease contract. In order to minimize the total cost of production and maintenance by redu...
Meniscal tears are the most common orthopaedic injuries, with chronic lesions comprising up to 56% of cases. In these situations, no benefit with surgical treatment is observed. Thus, the purpose of this study was to investigate the effectiveness and...
It is now suggested that the inhibition of biological programs that are associated with the tumor microenvironment may be critical to the diagnostics, prevention and treatment of cancer. On the other hand, a suitable wound microenvironment would acce...
The cornea and the skin are both organs that provide the outer barrier of the body. Both tissues have developed intrinsic mechanisms that protect the organism from a wide range of external threats, but at the same time also enable rapid restoration o...
In response to the influence of extreme disasters, damage to distribution lines and user outages, a parallel implementation strategy is proposed for emergency repair of disaster-damaged distribution networks and rapid restoration of power supply for...
Pressure vessels are subjected to deterioration and damage, which can significantly reduce their strength and loading capabilities. Among several procedures nowadays available to repair damaged steel pipelines, composite-repairing systems have become...
This paper is aimed to obtain the instantaneous availabilities (IAs) for the two-unit series system and parallel system with three states. By the compound
In this work, the effects of tool bias as a processing parameter on an additive friction stir deposition repair of AA7050-T7451 plates were investigated. In this study, the asymmetrical material flow effect was assessed by subjecting a machined groov...
The integrity of point cloud is the basis for smoothly ensuring subsequent data processing and application. For “Smart City” and “Scan to Building Information Modeling (BIM)”, complete point cloud data is essential. At present...
The effectiveness of repair work relies on whether the interface substrate can achieve sufficient bond strength when subjected to numerous stresses. This study investigated the bond properties of repaired normal concrete (NC-to-NC) elements, includin...
DNA-crosslinks are one of the most severe types of DNA lesions. Crosslinks (CLs) can be subdivided into DNA-intrastrand CLs, DNA-interstrand CLs (ICLs) and DNA-protein crosslinks (DPCs), and arise by various exogenous and endogenous sources. If left...
Re-Pairis a grammar compression scheme with favorably good compression rates. The computation of Re-Pair comes with the cost of maintaining large frequency tables, which makes it hard to compute Re-Pair on large-scale data sets. As a solution for thi...
Both robustness and self-repairing of the rhythmic behaviors generated by central pattern generators (CPGs) play significant roles in locomotion control. Although current CPG models have been established to mimic rhythmic outputs, the mechanisms by w...
To improve the post-earthquake resilience evaluation of concrete buildings with various construction types, this study presents a generalized recovery-based framework that ext-ends the FEMA P-58 methodology. The proposed method introduces a dynamic r...
A complex DNA repair network maintains genome integrity and genetic stability. In this study, the influence of edaphic factors on DNA damage and repair in wild wheat Triticum dicoccoides was addressed. Plants inhabiting two abutting microsites with d...
The use of PARP inhibitors (PARPi) is growing widely as FDA approvals have shifted its use from the recurrence setting to the frontline setting. In parallel, the population developing PARPi resistance is increasing. Here we review the role of PARP, D...
Time resolved data of DNA damage and repair after radiotherapy elucidates the relation between damage, repair, and cell survival. While well characterized in vitro, little is known about the time-course of DNA damage response in tumors sampled from i...
This study attempts to propose an availability optimization decision support design system for repairable n-stage mixed systems, in which different combinations of subsystems, such as parallel, standby, and k-out-of-q, are connected in series configu...
This research envisages a system composed of three subsystems connected in series. Each subsystem comprises three units connected in parallel. For the system to function, at least one unit per subsystem must remain operational. Unit failure is govern...
Background: The gut microbiome is crucial in sustaining intestinal balance and general health. Following rectal cancer surgery, the creation of a diverting stoma to protect the anastomosis results in a defunctioned colon, leading to dysbiosis. The ef...
G-quadruplexes (G4s), the most widely studied alternative DNA structures, are implicated in the regulation of the key cellular processes. In recent years, their involvement in DNA repair machinery has become the subject of intense research. Here, we...
Biomaterials and their applications are perhaps among the most dynamic areas of research within the field of biomedicine. Any advance in this topic translates to an improved quality of life for recipient patients. One application of a biomaterial is...
The purpose of this study is to explore the possibilities for the application of laser therapy in medicine and dentistry by analyzing lasers’ underlying mechanism of action on different cells, with a special focus on stem cells and mechanisms of repa...
In this work, an ACO routing protocol for mobile ad hoc networks based on AntHocNet is specified. As its predecessor, this new protocol, called AntOR, is hybrid in the sense that it contains elements from both reactive and proactive routing. Specific...
Late ruptures of abdominal aortic aneurysms post-endovascular aneurysm repair present a significant risk, occurring in about 0.9% of cases. The typical timeframe leading to rupture is roughly 37 months, with the primary factors often linked to endole...
Parallel operations by multiple trades on constrained workfaces pit safety against schedule. Static schedulers, scalar fatigue models, and standard evolutionary algorithms all struggle to reconcile the two. Simulation tackles the Parallel Task Matchi...
This paper proposes a system made up of four subsystems connected in sequence. The first and third subsystems each have one unit, the second has two, and the fourth has three. Every subsystem operates in parallel and is governed by the K-Out-of-n:G r...
This paper investigates the optimal maintenance strategies for a self-repairable component under detection at fixed time intervals. The failure process of a component is considered as two parallel and competing degradation processes: an internal degr...
Marine organisms with fast growth rates and great biological adaptive capacity might have biotechnological interests, since ecological competitiveness might rely on enhanced physiological or biochemical processes’ capability promoting protectio...
Many toxic agents can cause DNA double strand breaks (DSBs), which are in most cases quickly repaired by the cellular machinery. Using ionising radiation, we explored the kinetics of DNA lesion signaling and structural chromosome aberration formation...
Poly(ADP-ribose)polymerase-1 (PARP1) is a nuclear protein implicated in DNA repair, recombination, replication, and chromatin remodeling. The aim of this study was to evaluate possible differences between PARP1−/− and wild-type mice regarding inducti...
Alterations in the redox status and the DNA damage response (DDR) parameters are early, mechanistically interconnected drivers of carcinogenesis. Herein, we investigated whether such alterations, arising during the progression of Multiple Myeloma (MM...
In dialogue, laughter is a frequent non-verbal signal that can precede, follow, or overlap its antecedent—the laughable. Furthermore, the time alignment between the laughter and the laughable is dependent on who produces the laughable, whether...
The interaction between macromolecular chains and phospholipid membranes in aqueous solution was investigated using dissipative particle dynamics simulations. Two cases were considered, one in which the macromolecular chains were pulled along paralle...
Targeted genome editing is a powerful tool in reverse genetic studies of gene function in many aspects of biological and pathological processes. The CRISPR/Cas system or engineered endonucleases such as ZFNs and TALENs are the most widely used genome...
In the PALOMA trial, Papilocare® demonstrated efficacy in repairing low-grade cervical lesions related to human papillomavirus (HPV). This sub-analysis aimed to evaluate its efficacy in repairing these cervical lesions and clearing HPV in women a...
Members of the E2F transcription factor family regulate the expression of genes important for DNA replication and mitotic cell division in most eukaryotes. Homologs of the retinoblastoma (RB) tumor suppressor inhibit the activity of E2F factors, thus...
Skin wounds may lead to scar formation and impaired functionality. Remote ischemic preconditioning (RIPC) can induce the anti-inflammatory enzyme heme oxygenase-1 (HO-1) and protect against tissue injury. We aim to improve cutaneous wound repair by R...
The study of DNA repair in hyperthermophiles has the potential to elucidate the mechanisms of genome integrity maintenance systems under extreme conditions. Previous biochemical studies have suggested that the single-stranded DNA-binding protein (SSB...
Folate is an essential water-soluble vitamin in food and nutrition supplements. As a one-carbon source, it is involved in many central regulatory processes, such as DNA, RNA, and protein methylation as well as DNA synthesis and repair. Deficiency in...
The deep water environment is complex and variable, and underwater images are easily affected by light scattering, water absorption and other factors, resulting in blurred details and color distortion. The existing enhancement methods generally suffe...
The rapid development of machine learning, large language models, and related technologies has greatly increased the demand for data storage capacity. Therefore, the role of distributed storage systems in such applications has become more prominent....
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