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  • Article
  • Open Access
25 Citations
9,607 Views
9 Pages

Epidemiology of Healthcare-Associated Infections and Adherence to the HAI Prevention Strategies

  • Saleh A. Alrebish,
  • Hasan S. Yusufoglu,
  • Reem F. Alotibi,
  • Nawal S. Abdulkhalik and ,
  • Nehad J. Ahmed and
  • Amer H. Khan
  • + 1 author+ 0 author

26 December 2022

Healthcare-associated infections are widely considered one of the most common unfavorable outcomes of healthcare delivery. Ventilator-associated pneumonia, central line-associated bloodstream infections, and catheter-associated urinary tract infectio...

  • Review
  • Open Access
40 Citations
10,063 Views
12 Pages

How Does Hospital Microbiota Contribute to Healthcare-Associated Infections?

  • Flora Cruz-López,
  • Adrián Martínez-Meléndez and
  • Elvira Garza-González

Healthcare-associated infections (HAIs) are still a global public health concern, associated with high mortality and increased by the phenomenon of antimicrobial resistance. Causative agents of HAIs are commonly found in the hospital environment and...

(This article belongs to the Special Issue Recent Advances in Emerging Infectious Diseases)
  • Systematic Review
  • Open Access
7 Citations
7,885 Views
20 Pages

Nursing Students’ Knowledge Among Healthcare-Associated Infections: A Systematic Review

  • Vincenza Giordano,
  • Chiara Palazzo,
  • Caterina Mercuri,
  • Vittoria Verde and ,
  • Teresa Rea,
  • Patrizia Doldo and
  • Assunta Guillari
  • + 2 authors+ 0 author

Background: Healthcare-associated infections represent a significant public health problem, with a major impact on patient safety and quality of care. Nursing students play a central role in implementing infection prevention and control measures, yet...

  • Review
  • Open Access
17 Citations
8,792 Views
13 Pages

Implementation Strategies for Preventing Healthcare-Associated Infections across the Surgical Pathway: An Italian Multisociety Document

  • Massimo Sartelli,
  • Stefano Bartoli,
  • Felice Borghi,
  • Stefano Busani and ,
  • Andrea Carsetti,
  • Fausto Catena,
  • Nicola Cillara,
  • Federico Coccolini,
  • Andrea Cortegiani and
  • Maria Luisa Moro
  • + 17 authors+ 12 authors

Healthcare-associated infections (HAIs) result in significant patient morbidity and can prolong the duration of the hospital stay, causing high supplementary costs in addition to those already sustained due to the patient’s underlying disease....

(This article belongs to the Special Issue Antibiotic Treatment on Surgical Infections)
  • Review
  • Open Access
86 Citations
13,288 Views
12 Pages

Epidemiology and Prevention of Healthcare-Associated Infections in Geriatric Patients: A Narrative Review

  • Maria Luisa Cristina,
  • Anna Maria Spagnolo,
  • Luana Giribone,
  • Alice Demartini and
  • Marina Sartini

Demographic studies show that life expectancy is increasing in developed countries; increased longevity has also increased the share of the older population with often concomitant chronic conditions. An ageing population and increased comorbidities l...

(This article belongs to the Section Infectious Disease Epidemiology)
  • Systematic Review
  • Open Access
2,702 Views
29 Pages

Surveillance of Healthcare-Associated Infections in the WHO African Region: Systematic Review of Literature from 2011 to 2024

  • Laetitia Gahimbare,
  • Nathalie K. Guessennd,
  • Claude Mambo Muvunyi,
  • Walter Fuller and ,
  • Sheick Oumar Coulibaly,
  • Landry Cihambanya,
  • Pierre Claver Kariyo,
  • Olga Perovic,
  • Ambele Judith Mwamelo and
  • Yahaya Ali Ahmed
  • + 9 authors+ 4 authors

18 December 2025

Background: Evidence on HAIs in Africa is fairly common. Objectives: The main objective was to identify the surveillance tools used for healthcare–associated infections (HAIs) in countries in the WHO African Region. Secondary objectives focused...

  • Review
  • Open Access
29 Citations
8,545 Views
11 Pages

Healthcare-Associated Infections (HAIs): Challenges and Measures Taken by the Radiology Department to Control Infection Transmission

  • Ali Alamer,
  • Fawaz Alharbi,
  • Asim Aldhilan,
  • Ziyad Almushayti and ,
  • Khalefa Alghofaily,
  • Ayman Elbehiry and
  • Adil Abalkhail
  • + 2 authors+ 0 author

30 November 2022

Infections contracted during healthcare delivery in a hospital or ambulatory setting are collectively referred to as healthcare-associated infections (HAIs). Healthcare workers and patients alike are vulnerable to serious problems as a result of the...

(This article belongs to the Section Epidemiology and Vaccination)
  • Systematic Review
  • Open Access
29 Citations
8,175 Views
26 Pages

Advancing Patient Safety: The Future of Artificial Intelligence in Mitigating Healthcare-Associated Infections: A Systematic Review

  • Davide Radaelli,
  • Stefano Di Maria,
  • Zlatko Jakovski,
  • Djordje Alempijevic and ,
  • Ibrahim Al-Habash,
  • Monica Concato,
  • Matteo Bolcato and
  • Stefano D’Errico
  • + 3 authors+ 0 author

6 October 2024

Background: Healthcare-associated infections are infections that patients acquire during hospitalization or while receiving healthcare in other facilities. They represent the most frequent negative outcome in healthcare, can be entirely prevented, an...

(This article belongs to the Section Healthcare Quality, Patient Safety, and Self-care Management)
  • Article
  • Open Access
1 Citations
1,093 Views
13 Pages

3 November 2025

Background and Objectives: Changes in the incidence of healthcare-associated infections (HAIs) during the coronavirus disease 2019 (COVID-19) pandemic and during periods with fewer or more COVID-19 cases have been inconclusively studied. Compared wit...

(This article belongs to the Special Issue Emerging Strategies in Infection Control and Antimicrobial Therapy)
  • Systematic Review
  • Open Access
27 Citations
5,011 Views
21 Pages

7 November 2023

This study investigated how the Coronavirus Disease 2019 (COVID-19) pandemic has affected the rate of healthcare-associated infections (HAIs). PubMed, Scopus and Google Scholar were searched to identify potentially eligible studies published from Dec...

  • Proceeding Paper
  • Open Access
1 Citations
4,434 Views
7 Pages

30 September 2023

Healthcare-associated infections are serious public health problem. Besides antibacterial, antifungal, and antiviral therapies, one potential strategy for breaking the chain of infection transmission is via the installation of antibacterial surfaces....

(This article belongs to the Proceedings of The 15th International Aluminium Conference)
  • Systematic Review
  • Open Access
27 Citations
14,850 Views
17 Pages

Effectiveness of Infection Control Teams in Reducing Healthcare-Associated Infections: A Systematic Review and Meta-Analysis

  • Moe Moe Thandar,
  • Md. Obaidur Rahman,
  • Rei Haruyama,
  • Sadatoshi Matsuoka and ,
  • Sumiyo Okawa,
  • Jun Moriyama,
  • Yuta Yokobori,
  • Chieko Matsubara,
  • Mari Nagai and
  • Toshiaki Baba
  • + 6 authors+ 1 author

The infection control team (ICT) ensures the implementation of infection control guidelines in healthcare facilities. This systematic review aims to evaluate the effectiveness of ICT, with or without an infection control link nurse (ICLN) system, in...

(This article belongs to the Special Issue New Advances in Infection Control Research)
  • Review
  • Open Access
115 Citations
31,481 Views
29 Pages

An Overview of Healthcare Associated Infections and Their Detection Methods Caused by Pathogen Bacteria in Romania and Europe

  • Sándor Szabó,
  • Bogdan Feier,
  • Denisa Capatina,
  • Mihaela Tertis and ,
  • Cecilia Cristea and
  • Adina Popa
  • + 1 author+ 0 author

4 June 2022

Healthcare-associated infections can occur in different care units and can affect both patients and healthcare professionals. Bacteria represent the most common cause of nosocomial infections and, due to the excessive and irrational use of antibiotic...

(This article belongs to the Special Issue Clinical Research on Infectious Diseases: State of the Art)
  • Article
  • Open Access
54 Citations
8,436 Views
12 Pages

19 August 2014

Healthcare-associated infections (HAI) are a huge public health concern, particularly when the etiological agents are multidrug resistant. The ability of bacteria to develop biofilm is a helpful skill, both to persist within hospital units and to inc...

(This article belongs to the Special Issue Biofilm-Based Nosocomial Infections)
  • Article
  • Open Access
247 Views
18 Pages

Healthcare-Associated Infections with Pseudomonas spp. in a Neurosurgical Hospital: Epidemiological and Clinical Insights

  • Nicoleta Luchian,
  • Cristian Guțu,
  • Camer Salim,
  • Alina Pleșea-Condratovici and ,
  • Marius Gabriel Dabija,
  • Mădălina Irina Ciuhodaru,
  • Mădălina Duceac (Covrig),
  • Constantin Marcu,
  • Irina Luciana Gurzu and
  • Letiția Doina Duceac
  • + 7 authors+ 2 authors

19 October 2026

Background and Objectives: Healthcare-associated infections (HAIs) caused by Pseudomonas aeruginosa represent a challenge for healthcare systems worldwide, with significant incidence, high mortality, and increasing antibiotic resistance. This paper a...

(This article belongs to the Special Issue Antibiotic Resistance and Patient Safety: A Clinical Perspective)
  • Article
  • Open Access
6 Citations
2,972 Views
12 Pages

Increased Involvement of Klebsiellapneumoniae and Enterococcusfaecium in Healthcare-Associated Infections of Intensive Care Units in Taiwan

  • Yu-Ren Lin,
  • Yen-Yue Lin,
  • Chia-Peng Yu,
  • Ya-Sung Yang and ,
  • Chun-Gu Cheng and
  • Chun-An Cheng
  • + 1 author+ 0 author

11 October 2021

Background: Healthcare-associated infections (HAIs) cause increases in length of stay, mortality, and healthcare costs. A previous study conducted in Taiwan obtained similar results to those reported in Korea and Japan in 2015. Changes in microorgani...

(This article belongs to the Section Critical Care)
  • Review
  • Open Access
57 Citations
20,098 Views
15 Pages

Preventing and Controlling Healthcare-Associated Infections: The First Principle of Every Antimicrobial Stewardship Program in Hospital Settings

  • Massimo Sartelli,
  • Corrado P. Marini,
  • John McNelis,
  • Federico Coccolini and ,
  • Caterina Rizzo,
  • Francesco M. Labricciosa and
  • Patrizio Petrone
  • + 2 authors+ 0 author

20 September 2024

Antimicrobial resistance (AMR) is one of the main public health global burdens of the 21st century, responsible for over a million deaths every year. Hospital programs aimed at improving antibiotic use, referred to as antimicrobial stewardship progra...

(This article belongs to the Special Issue Successful Antimicrobial Stewardship Approaches to Address Nosocomial Infections)
  • Review
  • Open Access
363 Views
14 Pages

Patient Safety Implications of Opportunistic Pathogens and Healthcare-Associated Infections in COVID-19 Patients: A Narrative Review

  • Francesco De Micco,
  • Gianmarco Di Palma,
  • Davide Ferorelli,
  • Flavia Giacomobono and ,
  • Isabella Lima Arrais Ribeiro,
  • Johnys Berton Medeiros da Nóbrega and
  • Roberto Scendoni
  • + 2 authors+ 0 author

The COVID-19 pandemic has highlighted the increased vulnerability of hospitalized patients to healthcare-associated infections (HAIs), which significantly impact patient safety and clinical outcomes. This narrative review summarizes the main opportun...

  • Article
  • Open Access
79 Citations
4,881 Views
9 Pages

Predictive Analysis of Healthcare-Associated Blood Stream Infections in the Neonatal Intensive Care Unit Using Artificial Intelligence: A Single Center Study

  • Emma Montella,
  • Antonino Ferraro,
  • Giancarlo Sperlì,
  • Maria Triassi and ,
  • Stefania Santini and
  • Giovanni Improta
  • + 1 author+ 0 author

Background: Neonatal infections represent one of the six main types of healthcare-associated infections and have resulted in increasing mortality rates in recent years due to preterm births or problems arising from childbirth. Although advances in ob...

(This article belongs to the Section Infectious Diseases, Chronic Diseases, and Disease Prevention)
  • Article
  • Open Access
5 Citations
3,843 Views
12 Pages

(1) Background: Firefighters spend about 64% of their time responding to medical emergencies and providing medical care without a patient history, which can render them vulnerable to healthcare-associated infections (HAI). Infection prevention, contr...

(This article belongs to the Special Issue Infectious Disease Epidemiology 2020: The Importance of (Re)Emerging Occupational Infectious Agents)
  • Article
  • Open Access
9 Citations
16,902 Views
12 Pages

Implementation of 2% Chlorhexidine Bathing to Reduce Healthcare-Associated Infections Among Patients in the Intensive Care Unit

  • Hsu-Liang Chang,
  • Tzu-Ying Liu,
  • Po-Shou Huang,
  • Chin-Hwan Chen and ,
  • Chia-Wen Yen,
  • Hui-Zhu Chen,
  • Shin-Huei Kuo,
  • Tun-Chieh Chen,
  • Shang-Yi Lin and
  • Po-Liang Lu
  • + 5 authors+ 0 author

Healthcare-associated infections (HAIs) significantly increase morbidity, mortality, length of hospital stays, and costs, particularly among ICU patients. Despite standard interventions, catheter-associated urinary tract infections (CAUTI) and centra...

(This article belongs to the Special Issue Overview of Healthcare-Associated Infections)
  • Article
  • Open Access
1 Citations
710 Views
15 Pages

Trends in Healthcare-Associated Infections Prevalence and Risk Factors: Repeated Point Prevalence Survey in a Milan Tertiary Hospital (2022–2025)

  • Flavia Pennisi,
  • Martino Alberto Godoy,
  • Tommaso Camuffo,
  • Sabrina Caruccio and ,
  • Giusy D’Alterio,
  • Rosella Nebbia,
  • Carola Simone,
  • Arjun Sarabhai Verma,
  • Carlo Signorelli and
  • Matteo Moro
  • + 6 authors+ 1 author

Background: Healthcare-associated infections (HAIs) and antimicrobial resistance are major burdens in tertiary care hospitals. Repeated point prevalence surveys (PPSs) offer a pragmatic approach to monitor temporal changes and guide infection prevent...

(This article belongs to the Special Issue Healthcare-Associated Infections (HAIs): Prevention, Control and Surveillance, 2nd Edition)
  • Article
  • Open Access
1,603 Views
15 Pages

Healthcare-Associated Infections, Antibiotic Use, and Invasive Devices: A Repeated Point Prevalence Survey

  • Maria Costantino,
  • Anna Maria Della Corte,
  • Valentina Giudice,
  • Luigi Fortino and ,
  • Maria Nappo,
  • Giovanni Boccia,
  • Vittoria Satriani,
  • Giuseppe Panzuto,
  • Walter Longanella and
  • Antonella Maisto
  • + 6 authors+ 1 author

Background: Healthcare-associated infections (HAIs) and antimicrobial resistance are major global public health challenges, influenced by patient clinical complexity and prescribing practices. Methods: Three-point prevalence surveys (PPSs) were condu...

  • Article
  • Open Access
6 Citations
1,367 Views
17 Pages

Burden of Healthcare-Associated Infections on Mortality Among COVID-19 Hospitalized Patients

  • Corina Voinea,
  • Elena Mocanu,
  • Elena Dantes,
  • Sanda Jurja and ,
  • Ana-Maria Neculai,
  • Aurora Craciun and
  • Sorin Rugina
  • + 2 authors+ 0 author

21 November 2025

Background: Healthcare-associated infections (HAIs) are a significant public health problem, having a decisive impact on the prognosis of patients hospitalized with COVID-19. In Romania, the absence of a uniform reporting system and the lack of epide...

(This article belongs to the Special Issue Advances in Pulmonary Disease Management and Innovation in Treatment)
  • Review
  • Open Access
3 Citations
3,464 Views
13 Pages

Knowledge of Medical Imaging Professionals on Healthcare-Associated Infections: A Systematic Review and Meta-Analysis

  • Suresh Sukumar,
  • Shovan Saha,
  • Winniecia Dkhar,
  • Nitika C. Panakkal and ,
  • Visakh Thrivikraman Nair,
  • Tulasiram Bommasamudram,
  • K Vaishali,
  • Ravishankar Nagaraja,
  • Sneha Ravichandran and
  • Rajagopal Kadavigere
  • + 5 authors+ 0 author

Healthcare-associated infections (HCAIs) are a significant concern for both healthcare professionals and patients. With recent advances in imaging modalities, there is an increase in patients visiting the radiology department for diagnosis and therap...

(This article belongs to the Special Issue Advances in Occupational Health and Safety Management)
  • Article
  • Open Access
1 Citations
736 Views
18 Pages

Healthcare-Associated Infections in Deceased Stroke Patients in a Romanian Neurological ICU: A Retrospective Descriptive Study

  • Simona Ioana Adriana Mlendea (Gălbineanu),
  • Alin Kraft,
  • Cristian Falup-Pecurariu,
  • Tatiana Gianina Melicianu and
  • Laurențiu Dănuț Nedelcu

Healthcare-associated infections (HAIs) are clinically relevant complications in critically ill stroke patients, particularly in neurological intensive care settings, where severe neurological injury, dysphagia, immobilization, invasive device exposu...

(This article belongs to the Special Issue Infectious Disease Surveillance in Romania: Third Edition)
  • Article
  • Open Access
5 Citations
1,274 Views
7 Pages

Healthcare-associated infections in Northern Russia: Results of ten point-prevalence surveys in 2006–2010

  • Ekaterina A. Krieger,
  • Andrej M. Grjibovski,
  • Olga V. Samodova and
  • Hanne M. Eriksen

16 June 2015

Background and objective: Statistics on healthcare-associated infections (HAIs) in Russia is scarce and has been considered to suffer from underreporting. We assessed the prevalence and changes in the prevalence of HAIs over 5 years and identified fa...

  • Article
  • Open Access
34 Citations
5,493 Views
26 Pages

Predictive Modeling of ICU Healthcare-Associated Infections from Imbalanced Data. Using Ensembles and a Clustering-Based Undersampling Approach

  • Fernando Sánchez-Hernández,
  • Juan Carlos Ballesteros-Herráez,
  • Mohamed S. Kraiem,
  • Mercedes Sánchez-Barba and
  • María N. Moreno-García

4 December 2019

Early detection of patients vulnerable to infections acquired in the hospital environment is a challenge in current health systems given the impact that such infections have on patient mortality and healthcare costs. This work is focused on both the...

(This article belongs to the Section Computing and Artificial Intelligence)
  • Article
  • Open Access
150 Views
14 Pages

P-GRISS Program: An Integrated Approach for the Prevention of Healthcare-Associated Infections and Rapid Management of Sepsis in Intensive Care

  • Antonio Scarano,
  • Fabio Di Carlo,
  • Sergio Alexandre Gehrke,
  • Guia Basoccu Faroni and
  • Fulvio Caracciolo

25 October 2026

Healthcare-Associated Infections (HAIs) are among the leading causes of morbidity and mortality in critically ill patients admitted to intensive care units. The growing spread of multidrug-resistant (MDR), extensively drug-resistant (XDR), and totall...

(This article belongs to the Special Issue Antibiotic and Infection Stewardship in the ICU)
  • Communication
  • Open Access
5 Citations
2,816 Views
8 Pages

Implementing a Personalized Antimicrobial Stewardship Program for Women with Gynecological Cancers and Healthcare-Associated Infections

  • Simona Di Giambenedetto,
  • Alberto Borghetti,
  • Lorena Quagliozzi,
  • Valeria Gallucci and ,
  • Francesca Lombardi,
  • Arturo Ciccullo,
  • Anna Fagotti,
  • Enrica Tamburrini and
  • Giovanni Scambia
  • + 4 authors+ 0 author

18 April 2022

Healthcare-associated infections (HCAIs) represent a major cause of morbidity and mortality in gynecologic cancer patients, requiring personalized cures. A retrospective study on gynecologic patients with HCAIs, managed through an antimicrobial stewa...

(This article belongs to the Special Issue Personalized Medicine and Multidisciplinary Approach in a Clinical Research Hospital)
  • Review
  • Open Access
11 Citations
4,754 Views
26 Pages

12 September 2025

Healthcare-associated infections (HAIs) represent one of the most persistent challenges in modern healthcare delivery, affecting millions of patients worldwide and imposing substantial clinical and economic burdens on healthcare systems. The emergenc...

(This article belongs to the Section Biology and Medicines)
  • Article
  • Open Access
14 Citations
3,557 Views
12 Pages

Microbiology of Healthcare-Associated Infections: Results of a Fourth National Point Prevalence Survey in Serbia

  • Ivana Ćirković,
  • Ljiljana Marković-Denić,
  • Milica Bajčetić,
  • Gorana Dragovac and ,
  • Zorana Đorđević,
  • Vesna Mioljević,
  • Danijela Urošević,
  • Vladimir Nikolić,
  • Aleksa Despotović and
  • Vesna Šuljagić
  • + 8 authors+ 3 authors

Millions of patients acquire healthcare-associated infections (HAIs) every year, putting them at risk for serious complications and prolonged hospitalization. Point prevalence surveys (PPS), guided by the European Centre for Disease Prevention and Co...

(This article belongs to the Special Issue Healthcare-Associated Infection, Antibiotic Resistance and Treatment)
  • Article
  • Open Access
12 Citations
2,829 Views
12 Pages

Antibacterial Textile Coating Armoured with Aggregation-Induced Emission Photosensitisers to Prevent Healthcare-Associated Infections

  • Resmarani Sahu,
  • Neethu Ninan,
  • Ngoc Huu Nguyen,
  • Jianzhong Wang and ,
  • Krasimir Vasilev,
  • Vi Khanh Truong and
  • Youhong Tang
  • + 2 authors+ 0 author

In the quest to curtail the spread of healthcare-associated infections, this work showcases the fabrication of a cutting-edge antibacterial textile coating armoured with aggregation-induced emission photosensitisers (AIE PS) to prevent bacterial colo...

(This article belongs to the Section Photochemistry)
  • Article
  • Open Access
69 Citations
8,750 Views
16 Pages

Healthcare-associated infections (HAIs) occurring in patients treated in an intensive care unit (ICU) are serious complications in the treatment process. Aetiological factors of these infections can have an impact on treatment effects, treatment dura...

(This article belongs to the Section Global Health)
  • Article
  • Open Access
24 Citations
5,078 Views
12 Pages

Introduction. Healthcare-associated infections (HAIs) are a serious problem of modern medicine. Patients hospitalized in intensive care units (ICUs) develop HAI significantly more often than patients in other hospital units. Materials and Methods. An...

(This article belongs to the Section Infectious Disease Epidemiology)
  • Article
  • Open Access
1 Citations
661 Views
19 Pages

Clinical Outcomes and Risk Factors of Healthcare-Associated Infections in Surgical Wards: A Retrospective Cohort Study

  • Andreea Mihaela Sandu,
  • Corneliu Ovidiu Vrancianu,
  • Marian Necula,
  • Roxana-Elena Cristian and ,
  • Ana-Catalina Tantu,
  • Alina Păunescu,
  • Daniel Diaconescu and
  • Monica Marilena Tantu
  • + 3 authors+ 0 author

Background and Objectives: Healthcare-associated infections (HAIs) remain a major cause of morbidity and mortality among hospitalized patients. During the COVID-19 pandemic, SARS-CoV-2 infection emerged as a major contributor to HAIs, alongside Clost...

(This article belongs to the Special Issue Emerging Strategies in Infection Control and Antimicrobial Therapy)
  • Article
  • Open Access
10 Citations
1,912 Views
16 Pages

Clinical and Epidemiological Aspects on Healthcare-Associated Infections with Acinetobacter spp. in a Neurosurgery Hospital in North-East Romania

  • Nicoleta Luchian,
  • Iulia Olaru,
  • Alina Pleșea-Condratovici,
  • Mădălina Duceac (Covrig) and ,
  • Mirela Mătăsaru,
  • Marius Gabriel Dabija,
  • Eva Maria Elkan,
  • Vlad Andrei Dabija,
  • Lucian Eva and
  • Letitia Doina Duceac
  • + 5 authors+ 0 author

Background and Objectives: Healthcare-associated infections (HAIs) are on the rise worldwide because the range of etiologic agents involved is very diverse and their antimicrobial resistance poses a threat to population health in the third millennium...

(This article belongs to the Section Epidemiology & Public Health)
  • Article
  • Open Access
15 Citations
3,818 Views
13 Pages

Healthcare-Associated Bloodstream Infections Due to Multidrug-Resistant Acinetobacter baumannii in COVID-19 Intensive Care Unit: A Single-Center Retrospective Study

  • Karolina Dobrović,
  • Tea Škrobo,
  • Katarina Selec,
  • Marko Jelić and ,
  • Rok Čivljak,
  • Jasminka Peršec,
  • Sanja Sakan,
  • Nikolina Bušić,
  • Antonija Mihelčić and
  • Arjana Tambić Andrašević
  • + 6 authors+ 1 author

Healthcare-associated infections are an emerging cause of morbidity and mortality in COVID-19 intensive care units (ICUs) worldwide, especially those caused by multidrug-resistant (MDR) pathogens. The objectives of this study were to assess the incid...

(This article belongs to the Special Issue Bacterial Pathogens Associated with Bacteremia)
  • Article
  • Open Access
564 Views
15 Pages

Silver Nanoparticle-Functionalized Medical Devices for Primary Prevention of Healthcare-Associated Infections: In Vitro Efficacy Against Multidrug-Resistant Clinical Isolates

  • Daniela Chirizzi,
  • Rebecca Pellegrino,
  • Federica Paladini,
  • Fabiana D’Urso and ,
  • Mauro Pollini and
  • Francesco Broccolo
  • + 1 author+ 0 author

Healthcare-associated infections represent a global public health challenge, primarily driven by biofilm-forming multidrug-resistant pathogens on medical device surfaces, leading to high morbidity, mortality, and healthcare costs. As antibiotic strat...

(This article belongs to the Section Antimicrobial Agents and Resistance)
  • Article
  • Open Access
2 Citations
595 Views
15 Pages

Cumulative Vulnerability in Cardiac Critical Care: A Framework for Understanding Healthcare-Associated Infections and Their Progression to Severe Infection and Sepsis

  • Daniela Mirela Vîrtosu,
  • Angela Dragomir,
  • Simina Crișan,
  • Silvia Luca and ,
  • Oana Pătru,
  • Ruxandra-Maria Băghină,
  • Mihai-Andrei Lazăr,
  • Alina-Ramona Cozlac,
  • Stela Iurciuc and
  • Constantin Tudor Luca
  • + 5 authors+ 0 author

Background and Objectives: Healthcare-associated infections (HAIs) remain a relevant complication in coronary care units (CCUs), particularly among patients with cardiac dysfunction requiring invasive monitoring and prolonged hospitalization. In this...

(This article belongs to the Special Issue Global Perspectives on Sepsis: Epidemiology, Awareness and Treatment Strategies)
  • Article
  • Open Access
5 Citations
3,106 Views
14 Pages

Hospital infection prevention is critical to patient safety, yet data on the prevalence and contributing factors of healthcare-associated infections (HAIs) in Aljouf, Saudi Arabia, are scarce. This retrospective cross-sectional study aimed to investi...

(This article belongs to the Special Issue Healthcare-Associated Infections and Antimicrobial Therapy—2nd Edition)
  • Article
  • Open Access
17 Citations
3,572 Views
18 Pages

The Impact of Healthcare-Associated Infections in Patients Undergoing Oncological Microvascular Head and Neck Reconstruction: A Prospective Multicentre Study

  • Ana Ramos-Zayas,
  • Francisco López-Medrano,
  • Irene Urquiza-Fornovi,
  • Ignacio Zubillaga and ,
  • Ramón Gutiérrez,
  • Gregorio Sánchez-Aniceto,
  • Julio Acero,
  • Fernando Almeida,
  • Ana Galdona and
  • José Luis Cebrián
  • + 7 authors+ 2 authors

27 April 2021

(1) Background: Healthcare-associated infections (HAIs) after head and neck free-flap reconstruction are a common postoperative complication. Risk factors for HAIs in this context and their consequences have not been adequately described. (2) Methods...

(This article belongs to the Special Issue Surgical Treatment of Head and Neck Squamous Cell Carcinomas (HNSCC))
  • Article
  • Open Access
240 Views
27 Pages

Carbapenem-Resistant and Extensively Drug-Resistant Gram-Negative Healthcare-Associated Infections in a Romanian Tertiary Infectious Diseases Hospital: Phenotypic Landscape, Stewardship Gaps and Outcomes (2024–2025)

  • Răzvan Roșca,
  • Călin Muntean,
  • Mirela Frandeș,
  • Ruxandra Laza and ,
  • Daian-Ionel Popa,
  • Victor Bogdan Buciu,
  • Cătălin Prodan-Bărbulescu,
  • Mădălina-Ianca Șuba and
  • Sorina Maria Denisa Laitin
  • + 4 authors+ 0 author

10 October 2026

Background/Objectives: Romania reports among the highest rates of carbapenem-resistant Gram-negative bacteria in the European Union, but patient-level data on healthcare-associated infections (HAIs) are scarce. We characterised carbapenem resistance,...

(This article belongs to the Special Issue Antimicrobial Resistance and Epidemiological Study of Clinically Relevant Pathogens, 2nd Edition)
  • Article
  • Open Access
2 Citations
2,600 Views
13 Pages

Incorporation of Ceragenins into Medical Adhesives and Adhesive Scar Tape to Prevent Microbial Colonization Common in Healthcare-Associated Infections

  • Aaron Zaugg,
  • Elliot Sherren,
  • Rebekah Yi,
  • Alex Farnsworth and ,
  • Fetutasi Pauga,
  • Anna Linder,
  • Lauren Kelly,
  • Meg Takara,
  • McKenna Hoather and
  • Paul B. Savage
  • + 13 authors+ 8 authors

24 October 2024

Background/Objectives: Healthcare-associated infections involving surgical sites, skin trauma, and devices penetrating the skin are a frequent source of increased expense, hospitalization periods, and adverse outcomes. Medical adhesives are often emp...

(This article belongs to the Section Antimicrobial Materials and Surfaces)
  • Article
  • Open Access
4 Citations
1,093 Views
22 Pages

Etiologic Patterns and Evolution of Healthcare-Associated Infections in the Pandemic and Post-Pandemic Periods: A County-Level Multicenter Study from Southeastern Romania

  • Corina Voinea,
  • Elena Mocanu,
  • Elena Dantes,
  • Sanda Jurja and ,
  • Ana-Maria Neculai,
  • Aurora Craciun,
  • Lucian Serbanescu,
  • Ana-Maria Dascalu,
  • Mihaela Cezarina Mehedinti and
  • Sorin Rugina
  • + 5 authors+ 0 author

15 February 2026

Background/Objectives: Healthcare-associated infections (HAIs) remain a major source of morbidity, mortality, and healthcare burden, and were profoundly affected by the COVID-19 pandemic through changes in case mix, care organization, and antimicrobi...

  • Article
  • Open Access
4 Citations
2,207 Views
21 Pages

Antibiotic Use, Healthcare-Associated Infections, and Antimicrobial Resistance in Intensive Care Unit of a Serbian Tertiary University Hospital, 2018–2024: An Ecological Analysis

  • Vesna Šuljagić,
  • Vojislava Nešković,
  • Duško Maksimović,
  • Ivo Udovičić and ,
  • Danijela Đurić-Petković,
  • Nenad Perišić,
  • Ivan Leković,
  • Đorđe Taušan,
  • Bojan Rakonjac and
  • Nemanja Rančić
  • + 6 authors+ 1 author

4 November 2025

Background: Healthcare-associated infections (HAIs), antimicrobial resistance (AMR), and antibiotic use (AU) remain critical challenges in intensive care units (ICUs). Reliable long-term surveillance is essential to inform stewardship programs and in...

(This article belongs to the Special Issue Nosocomial Infections and Complications in ICU Settings)
  • Article
  • Open Access
10 Citations
4,065 Views
16 Pages

Point-Prevalence Survey of Antimicrobial Use and Healthcare-Associated Infections in Four Acute Care Hospitals in Kazakhstan

  • Yuliya Semenova,
  • Aizhan Yessmagambetova,
  • Zaure Akhmetova,
  • Manar Smagul and ,
  • Akniyet Zharylkassynova,
  • Bibigul Aubakirova,
  • Kateryna Soiak,
  • Zhanar Kosherova,
  • Ainur Aimurziyeva and
  • Lisa Lim
  • + 7 authors+ 2 authors

17 October 2024

Background/Objectives: Few studies have examined the prevalence of healthcare-associated infections (HAIs) and antimicrobial use (AMU) in acute care hospitals in Kazakhstan. This study aimed to address this gap by conducting a point-prevalence survey...

(This article belongs to the Special Issue Preventing Antimicrobial Resistance in Hospitals: Infection Control and Antibiotic Use)
  • Review
  • Open Access
1 Citations
661 Views
18 Pages

Global Surveillance of Healthcare-Associated Infections in Long-Term Care Facilities: A Narrative Review

  • Luisa-Andreea Gheorghe,
  • Carmen-Cristina Vasile,
  • Liviu-Iulian Rotaru,
  • Maria Dorina Crăciun and ,
  • Irina Magdalena Dumitru,
  • Daniela Pițigoi and
  • Carmen Daniela Chivu
  • + 2 authors+ 0 author

Healthcare-associated infections (HAIs) in long-term care facilities (LTCFs) are a public health problem worldwide. The aim of this narrative review is to summarize and to provide a comprehensive overview of the current surveillance methods used in L...

(This article belongs to the Special Issue Infectious Disease Surveillance in Romania: Second Edition)
  • Article
  • Open Access
15 Citations
7,486 Views
12 Pages

A Potential Way to Decrease the Know-Do Gap in Hospital Infection Control in Vietnam: “Providing Specific Figures on Healthcare-Associated Infections to the Hospital Staff Can ‘Wake Them Up’ to Change Their Behaviour”

  • La Thi Quynh Lien,
  • Eva Johansson,
  • Pham Thi Lan,
  • Nguyen Thi Kim Chuc and ,
  • Nguyen Thi Minh Thoa,
  • Nguyen Quynh Hoa,
  • Ho Dang Phuc,
  • Ashok J. Tamhankar and
  • Cecilia Stålsby Lundborg
  • + 4 authors+ 0 author

Adequate infection control plays a key role in preventing healthcare-associated infections (HAIs). This study aimed to explore staff perceptions of hospital infection control in a rural and an urban hospital in Vietnam. Individual interviews were con...

(This article belongs to the Section Global Health)
  • Article
  • Open Access
8 Citations
4,673 Views
13 Pages

Healthcare-associated infections (HAI) refer to infections that patients may acquire from healthcare facilities through nursing activities. Nursing students involved in patient care are regularly exposed to an array of pathogens and clinical practicu...

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