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Microorganisms
Special Issues
Healthcare-Associated Infections and Antimicrobial Therapy—2nd Edition
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Healthcare-Associated Infections and Antimicrobial Therapy—2nd Edition

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Medical Microbiology".

Deadline for manuscript submissions: 30 April 2025 | Viewed by 860

Special Issue Editors

Dr. Diamantis P. Kofteridis

E-Mail Website
Guest Editor
Department of Internal Medicine, University Hospital of Heraklion, Crete, Greece
Interests: antimicrobial stewardship; infection control; infectious diseases
Special Issues, Collections and Topics in MDPI journals
Dr. Petros Ioannou

E-Mail Website
Guest Editor
School of Medicine, University of Crete, Heraklion, Greece
Interests: infectious diseases; internal medicine; HIV/AIDS; infective endocarditis; blood-stream infections
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue is the continuation of our previous Special Issue, entitled "Healthcare-Associated Infections and Antimicrobial Therapy".

Hospital-acquired infections occur frequently among hospitalized patients and are associated with a significant increase in morbidity and mortality, with the most common hospital-acquired infections including bloodstream infections and respiratory tract and urinary tract infections. Currently, several changes regarding the epidemiology and microbiology of hospital-acquired infections are being noted, and these mostly have to do with the increasing problem of antimicrobial resistance either in Gram-positives, such as methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus, or in Gram-negatives, such as carbapenem-resistant Enterobacterales, extensively-drug resistant and pan-drug resistant Acinetobacter baumannii, and multi-drug resistant Pseudomonas aeruginosa. The problem of increasing antimicrobial resistance leaves few therapeutic options, leading to the revival of old antibiotics or the use of antimicrobial combinations in difficult-to-treat pathogens.

To arrive at a better understanding of the problem of hospital-acquired infections and the changes in the antimicrobial treatment thereof, this Special Issue aims to bring together original studies and literature reviews related to the epidemiology, microbiology, clinical characteristics, treatment, and outcomes of these infections. Furthermore, studies focusing on antimicrobial stewardship and infection control regarding hospital-acquired infections are also welcome.

Dr. Diamantis P. Kofteridis
Dr. Petros Ioannou
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • clinical microbiology
  • healthcare-associated infections
  • antimicrobial therapy

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Related Special Issue

Published Papers (1 paper)

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Research

16 pages, 788 KiB  
Article
Comparative Analysis of Bacterial Conjunctivitis in the Adult and Pediatric Inpatient vs. Outpatient Population
by Adela Voinescu, Corina Musuroi, Monica Licker, Delia Muntean, Silvia-Ioana Musuroi, Luminita Mirela Baditoiu, Dorina Dugaesescu, Romanita Jumanca, Mihnea Munteanu and Andrei Cosnita
Microorganisms 2025, 13(3), 473; https://doi.org/10.3390/microorganisms13030473 - 20 Feb 2025
Viewed by 576
Abstract
The etiology and resistance pattern of bacterial conjunctivitis varies depending on the patient’s care setting and age. A retrospective, observational study was conducted in a tertiary care teaching hospital. A total of 126 patients—76 adults and 50 children—diagnosed with conjunctival infection during inpatient [...] Read more.
The etiology and resistance pattern of bacterial conjunctivitis varies depending on the patient’s care setting and age. A retrospective, observational study was conducted in a tertiary care teaching hospital. A total of 126 patients—76 adults and 50 children—diagnosed with conjunctival infection during inpatient or ambulatory care were analyzed. In the samples of adult patients, isolates were represented by Gram-positive cocci (57.7%; Staphylococcus spp., S. pneumoniae) followed by Enterobacterales (17.97%; P. mirabilis, E. coli, Klebsiella spp.), and non-fermenters (7.69%; Pseudomonas spp., A. baumannii). Multidrug-resistant (52.17%) and extensively drug-resistant (21.73%) pathogens (predominantly Gram-negative bacilli) were identified in conjunctival swabs of hospitalized adult patients. The main isolates (55.77%) identified in children’s conjunctival swabs belonged to S. aureus, H. influenzae, and S. pneumoniae, followed by Enterobacterales (19.22%; E. coli, P. mirabilis, M. morganii) and fungi (3.48%). Methicillin-resistant S. aureus (35.71%) and extended-spectrum beta-lactamase-producing K. pneumoniae (8.7%) were identified in the pediatric subgroup of patients. In critically ill adult patients assisted in the intensive care or burn functional units, bacterial conjunctivitis followed the pattern of infections and antimicrobial resistance specific to these categories of patients. In the case of hospitalized children, conjunctivitis was an integral part of the age-related pathology. Full article
(This article belongs to the Special Issue Healthcare-Associated Infections and Antimicrobial Therapy—2nd Edition)
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