Emerging Strategies in Infection Control and Antimicrobial Therapy

Dear Colleagues,

Infectious diseases have remained a significant global health burden despite remarkable advancements in medical science. The historical reliance on antimicrobial agents since the mid-20th century has revolutionized infection management, saving countless lives. However, the overuse and misuse of antibiotics have led to the rapid emergence of antimicrobial resistance (AMR), threatening to undermine decades of medical progress. Hospital-acquired infections, community outbreaks of resistant pathogens, and the slow pace of new antibiotic development underscore the urgency for innovative and multidisciplinary approaches in infection control and antimicrobial therapy.

This Special Issue aims to highlight novel, evidence-based strategies designed to tackle these pressing challenges. The scope includes both preventive and therapeutic dimensions, ranging from advanced diagnostics, personalized medicine, and surveillance systems to next-generation antimicrobials, host-targeted therapies, and infection prevention protocols. We are particularly interested in bridging fundamental research with clinical applications, encouraging collaborations across microbiology, pharmacology, epidemiology, and healthcare policy.

We invite cutting-edge research articles, comprehensive reviews, and short communications that explore innovative methods in infection control and antimicrobial therapy. Topics of interest include (but are not limited to)

• Novel antimicrobial agents and drug delivery systems;
• Strategies to combat antimicrobial resistance (AMR);
• Rapid diagnostic tools and point-of-care technologies;
• Infection prevention and control practices in healthcare settings;
• Bacteriophage therapy and alternative therapeutics;
• Immunomodulatory and host-directed therapies;
• Surveillance programs and AI-driven predictive models;
• Microbiome manipulation and probiotic interventions.

By assembling contributions from leading experts and emerging voices in the field, this Special Issue seeks to foster a deeper understanding of current trends and catalyze transformative solutions to one of the most critical health threats of our time.

Prof. Dr. Doina Azoicai
Guest Editor

Prof. Dr. Carmen Manciuc
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medicina is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• microbial resistance
• antibiotherapy
• infections
• control
• host-directed therapies