Increased Involvement of Klebsiellapneumoniae and Enterococcusfaecium in Healthcare-Associated Infections of Intensive Care Units in Taiwan
Abstract
:1. Introduction
2. Materials and Methods
2.1. Definitions
2.2. Statistical Analyses
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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2019 | 2015 | p | |
---|---|---|---|
Incidence density of healthcare-associated infections (‰) | 5.4 | 5.7 | <0.001 * |
Incidence density of bloodstream infections (‰) | 2.1 | 2.1 | 0.728 |
Incidence density of hospital-associated pneumonia (‰) | 0.6 | 0.8 | <0.001 * |
Incidence density of urinary tract infections (‰) | 1.9 | 2.1 | 0.001 * |
Incidence density of central line-associated bloodstream infections (‰) | 3.2 | 3.7 | <0.001 * |
Incidence density of ventilator-associated pneumonia (‰) | 0.7 | 1.1 | <0.001 * |
Incidence density of catheter-associated urinary tract infections (‰) | 2.7 | 3 | <0.001 * |
Percentage of device use rate in central line-associated bloodstream infections | 73.1 | 78.3 | <0.001 * |
Percentage of device use rate in ventilator-associated pneumonia | 54.9 | 70.2 | <0.001 * |
Percentage of device use rate in catheter-associated urinary tract infections | 87.9 | 90.3 | <0.001 * |
Klebsiella pneumoniae | 1156 | 1045 | <0.001 * |
Escherichia coli | 1021 | 1152 | 0.118 |
Candida albicans | 894 | 963 | 0.695 |
Enterococcus faecium | 867 | 711 | <0.001 * |
Pseudomonas aeruginosa | 766 | 976 | <0.001 * |
Acinetobacter baumannii | 684 | 963 | <0.001 * |
Staphylococcus aureus | 402 | 563 | <0.001 * |
CRKP | 37.5% | 23.2% | <0.001 * |
CRAB | 74.3% | 71% | 0.147 |
CRPA | 21.5% | 17.8% | 0.038 |
CR E. coli | 4% | 2.1% | 0.008 * |
MRSA | 62.2% | 70% | <0.001 * |
Vancomycin-resistant Enterococcus | 47.6% | 35.7% | <0.001 * |
Vancomycin-resistant Enterococcus faecium | 69.7% | 57.9% | <0.001 * |
CLABSIs (per 1000 Person-Days) | CAUTIs (per 1000 Person-Days) | VAP (per 1000 Person-Days) | |
---|---|---|---|
Medical intensive care units | 3.7 | 3.1 | 0.41 |
Surgical intensive care units | 3.16 | 2.54 | 0.85 |
Cardiac intensive care units | 3.21 | 2.98 | 0.29 |
Pediatric intensive care units | 1.99 | 1.45 | 0.58 |
General intensive care units | 3.02 | 2.59 | 0.98 |
Average | 3.18 | 2.73 | 0.7 |
2019 | Organism | 2015 | Organism | ||
---|---|---|---|---|---|
Urinary tract infections | Total (3744) | Percentage | Total (3990) | Percentage | |
1 | Escherichia coli | 18.1 | 1 | Escherichia coli | 19.8 |
2 | Candida albicans | 15 | 2 | Candida albicans | 16.9 |
3 | Enterococcus faecium | 10.1 | 3 | Enterococcus faecium | 8.5 |
4 | Klebsiella pneumoniae | 9.6 | 4 | Pseudomonas aeruginosa | 7.4 |
5 | Candida otherwise specified | 9.3 | 5 | Klebsiella pneumoniae | 7.3 |
Bloodstream infections | Total (4272) | Total (4138) | |||
1 | Klebsiella pneumoniae | 11.9 | 1 | Acinetobacter baumannii | 10.4 |
2 | Acinetobacter baumannii | 8.5 | 2 | Klebsiella pneumoniae | 9.6 |
3 | Enterococcus faecium | 8.5 | 3 | Enterococcus faecium | 7.2 |
4 | Candida otherwise specified | 7.9 | 4 | Staphylococcus aureus | 6.5 |
5 | Escherichia coli | 5.2 | 5 | Candida albicans | 6.2 |
Healthcare-acquired pneumonia | Toral (929) | Toral (1397) | |||
1 | Pseudomonas aeruginosa | 19.9 | 1 | Pseudomonas aeruginosa | 22.5 |
2 | Klebsiella pneumoniae | 17.5 | 2 | Acinetobacter baumannii | 18 |
3 | Acinetobacter baumannii | 14.2 | 3 | Klebsiella pneumoniae | 16.2 |
4 | Staphylococcus aureus | 8.2 | 4 | Staphylococcus aureus | 9 |
5 | Enterobacter species | 5.9 | 5 | Enterobacter species | 6.2 |
Surgical site infections | Total (699) | Total (698) | |||
1 | Pseudomonas aeruginosa | 11.7 | 1 | Pseudomonas aeruginosa | 12.8 |
2 | Klebsiella pneumoniae | 10.3 | 2 | Klebsiella pneumoniae | 10.2 |
3 | Enterococcus faecium | 8.4 | 3 | Escherichia coli | 9.6 |
3 | Escherichia coli | 8.4 | 4 | Enterobacter cloacae | 8.2 |
5 | Acinetobacter baumannii | 6.3 | 5 | Staphylococcus aureus | 7.2 |
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Lin, Y.-R.; Lin, Y.-Y.; Yu, C.-P.; Yang, Y.-S.; Cheng, C.-G.; Cheng, C.-A. Increased Involvement of Klebsiellapneumoniae and Enterococcusfaecium in Healthcare-Associated Infections of Intensive Care Units in Taiwan. Healthcare 2021, 9, 1349. https://doi.org/10.3390/healthcare9101349
Lin Y-R, Lin Y-Y, Yu C-P, Yang Y-S, Cheng C-G, Cheng C-A. Increased Involvement of Klebsiellapneumoniae and Enterococcusfaecium in Healthcare-Associated Infections of Intensive Care Units in Taiwan. Healthcare. 2021; 9(10):1349. https://doi.org/10.3390/healthcare9101349
Chicago/Turabian StyleLin, Yu-Ren, Yen-Yue Lin, Chia-Peng Yu, Ya-Sung Yang, Chun-Gu Cheng, and Chun-An Cheng. 2021. "Increased Involvement of Klebsiellapneumoniae and Enterococcusfaecium in Healthcare-Associated Infections of Intensive Care Units in Taiwan" Healthcare 9, no. 10: 1349. https://doi.org/10.3390/healthcare9101349