14 September 2021
Frostbite is tissue damage caused by freezing temperatures and constitutes an important cause of morbidity in cold climate zones and high altitude. The direct effects of sub-zero temperatures lead to tissue freezing, electrolyte shifts and pH alterat...
Rapid rewarming is the most conventional and primary treatment for frostbite, yet effective adjunctive strategies remain absent. Conventional wound dressings, such as therapeutic hydrogels, tend to freeze and lack the necessary rewarming ability, ren...
Background: Frostbite injury is a thermal injury where ice crystals form in skin tissues and subsequently lead to damage due to prolonged exposure to cold temperatures below 0 °C. The extremities are mostly affected, leading to potential amputati...
Nitrous oxide has a wide range of medical applications, such as being used as an analgesic in general anesthesia, dental procedures, childbirth and sedation. Lately, it has also been employed as an inhalant recreational drug to induce brief euphoria....
Native to South America, the coypu (Myocastor coypus) is an invasive alien species (IAS) of Union concern. It was introduced to Germany a hundred years ago and is considered established in all German federal states. Between January and February 2021,...
Background: Frostbite is a severe injury characterized by tissue damage due to exposure to freezing temperatures. It often necessitates prompt medical intervention to prevent further complications such as necrosis and amputation. This case report exp...
Background: Frostbite injury creates an ischemic, hypoxic, and acidic microenvironment that often triggers severe oxidative stress and inflammation. Current therapeutic approaches are limited by low drug delivery efficiency and an inability to adequa...
Background and Objectives: Frostbite is a freezing injury that can lead to amputation. Current treatments include tissue rewarming followed by thrombolytic or vasodilators. Hyperbaric oxygen (HBO) therapy might decrease the rate of amputation by incr...
Many marine microorganisms synthesize exopolysaccharides (EPSs), and some of these EPSs have been reported to have potential in different fields. However, the pharmaceutical potentials of marine EPSs are rarely reported. The EPS secreted by the Artic...
Background: When the body temperature falls below 35 °C, a condition known as hypothermia occurs. This renders it impossible to regulate the body temperature and produce heat. In these cases, death is due to a cessation of vital functions and is...
An 83-year-old woman was admitted to the emergency department for a 7-day history of fatigue and progressive cyanosis in the feet and hands after cold exposure despite physical protective measures. Upon arrival, the patient presented with necrotic cu...
15 April 2019
In recent years, the incidence of frostbite has increased among healthy young adults who practice winter sports (skiing, mountaineering, ice climbing and technical climbing/alpinism) at both the professional and amateur levels. Moreover, given that t...
While thermal injuries to the external genitalia occur less often than burns to the trunk and extremities, such injuries can potentially leave patients with devastating lifelong sequelae. Though much is known about treating burns in commonly exposed...
14 February 2025
Wilderness medicine is a rapidly evolving field and has benefited from expanded research efforts. Moreover, with an escalating occurrence of severe and cataclysmic global climatologic events, human illness arising from interaction with wilderness and...
In the northern hemisphere countries, artichoke harvest occurs in winter months; consequently, they are exposed to cold temperatures. This can lead to frost injury, such as triggering the blistering of the cuticle and detachment of outer bracts, whic...
For optimal plant growth, carbon and nitrogen availability needs to be tightly coordinated. Mitochondrial perturbations related to a defect in complex I in the Arabidopsis thalianafrostbite1 (fro1) mutant, carrying a point mutation in the 8-kD Fe-S s...
In the original publication [...]
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal disease that may be treated utilizing thermal therapies. Cryoablation is an effective, minimally invasive therapy that has been utilized for the treatment of various cancers, offering patient...
This study collected data through microclimate monitoring, surface temperature measurements, and questionnaire surveys, and used indicators, such as the universal thermal climate index (UTCI), surface temperature (Ts), and wind chill temperature (tWC...
Multiple quantitative trait loci (QTLs) associated with fruit size have been reported in apple (Malus domestica Borkh.); however, few have been fully characterized and/or validated. A pedigree-based QTL analysis approach was used to examine the genet...
Anubias (Araceae) is a globally important group of ornamental aquatic plants. However, when temperatures drop to 10 °C, most species suffer obvious frostbite from cold stress, restricting winter cultivation and broader application. This study foc...
A cold injury can result in devastating outcomes, leading to significant morbidity and loss of distal extremities. Amputations are common after severe frostbite injuries with delayed presentation, often mediated by post-injury arterial thrombosis. Is...
Petrified ears is an uncommon clinical entity. It describes auricular cartilage hardening, due usually to ectopic calcification or, less commonly, ossification. The most common causes are frostbite and mechanical trauma. However, endocrinopathies hav...
14 February 2023
Background: Taiwan always had low case rates of COVID-19 compared with other countries due to its immediate control and preventive measures. However, the effects of its policies that started on 2020 for otolaryngology patients were unknown; therefore...
The last century brought about more rapid new developments in the treatment of burns, which significantly lowered the mortality of burn injuries. However, burns were already treated in antiquity, where the threshold from spirituality to scientific me...
Scrophularia lanceolata Pursh and Scrophularia marilandica L. are two common species within the Scrophulariaceae family that are endemic to North America. Historically, these species were used by indigenous peoples and colonialists to treat sunburn,...
Carbon dioxide (CO2) is a non-toxic asphyxiant gas that, once released, can pose severe risks, including suffocation, poisoning, frostbite, and even death. As a critical component of carbon capture, utilization, and storage (CCUS) technology, CO2 pip...
In this study, the dynamic mechanical properties of red sandstone at low temperatures were studied by performing SHPB dynamic impact tests. According to damage and energy theories, the influences of different low temperatures on the dynamic strength,...
Hydrogen energy is considered a crucial clean energy carrier for replacing fossil fuels in the future. Liquid hydrogen (LH2), with its economic advantages and high purity, is central to the development of future hydrogen refueling stations (HRSs). Ho...
NK-4 plays a key role in the treatment of various diseases, such as in hay fever to expect anti-allergic effects, in bacterial infections and gum abscesses to expect anti-inflammatory effects, in scratches, cuts, and mouth sores from bites inside the...
Frozen vegetables are increasingly valued for their nutritional stability and year-round availability. This study provides a comprehensive assessment of twenty commercially available frozen vegetable blends obtained from retail markets in Poland. Ana...
One of the major challenges in dermal drug delivery is the adequate penetration of the active compound into the skin without causing any skin irritation and inflammation. Nanocrystals (NCs) are nanoscale particles, and their sizes are below 1000 nm....
Global food production faces immense pressure, much of which can be attributed to climate change. A detailed evaluation of the impact of climate change on the yield of staple crops in Kazakhstan, a major food exporter, is required for more scientific...
Due to the cold and dry climate during the winter season of Central Asia, in order to prevent frostbite and vines drying out for wine grapes, the common methods are burying the vines in winter under a thick layer of soil and then cleaning them out in...
Some mega-sport events such as the Winter Olympics are usually held in areas accompanied by cold environment, which has a great risk of frostbite and safety for pedestrians. Releasing guidance information have become a good way for managers to reduce...
Background/Objectives: Patients with Parkinson’s disease (PD) often have cold hands and experience frostbite. The diagnostic criteria for multiple system atrophy (MSA) also describe cold and discolored hands; however, in our clinical experience...
Due to the material properties of current ski face masks for adolescents, moisture in exhaled air can become trapped within the material fibers and freeze, leading to potential issues such as breathing difficulties and increased risk of facial frostb...
To improve the accuracy of detecting external defects in seed potatoes and address the reliance of current hyperspectral imaging methods on single-dimensional data, this study proposes a multi-dimensional spectral–spatial information fusion app...
Background: Aicardi–Goutières syndrome (AGS) is a rare genetic disorder characterized by microcephaly, white matter lesions, numerous intracranial calcifications, chilblain skin lesions and high levels of interferon-α (IFN-α)...
16 March 2021
(1) Background: Today’s elite alpinists target K2 and Everest in midwinter. This study aimed to asses and compare weather at the summits of both peaks in the climbing season (Everest, May; K2, July) and the midwinter season (January and February). (2...
Fishing is a widely practiced recreational activity that offers psychological, physical, and social benefits, but it also poses risks such as acute trauma and chronic overuse injuries. This narrative review aims to (1) synthesize current evidence on...
Background: Cryoablation is a minimally invasive technique that is being investigated as an alternative to surgery for early-stage breast cancer. Its potential advantages include outpatient treatment under local anaesthesia, favourable cosmetic outco...