In this work, the effects of tool bias as a processing parameter on an additive friction stir deposition repair of AA7050-T7451 plates were investigated. In this study, the asymmetrical material flow effect was assessed by subjecting a machined groov...
Repairers may play a substantial role in the shift from a linear (make, use, dispose) to a more circular economy, where resources are continually reused and waste is minimized, which is therefore by definition more sustainable. Repaired defective pro...
Determining appropriate intervention thresholds for pavement surface repairs is a fundamental challenge in pavement management. In practice, these thresholds are often defined using inspection conditions that are not observed at the time of repair, r...
Umbilical cord mesenchymal stem cells (UC-MSCs) possess the capabilities of differentiation and immune modulation, which endow them with therapeutic potential in the treatment of type 2 diabetes mellitus (T2DM). In this study, to investigate the repa...
Ionizing radiation (IR) is considered a traditional mutagen and genotoxic agent. Exposure to IR affects in all cases biological systems and living organisms from plants to humans mostly in a pernicious way. At low (<0.1 Gy) and low-to-medium doses...
Background/Objectives: Deltoid ligament injury has been reported in up to 40% of ankle fractures, as confirmed by arthroscopy. Despite the frequency of this injury, there are multiple methods of fixation, including use of sutures, anchors and grafts,...
Embedded programs are not only inseparable from our daily lives but are also widely used in aerospace, medical devices, and other fields that require very high security and stability. The uncertainty and randomness of the large amount of data generat...
Algal polysaccharides have been linked to repair signaling pathways related to transforming growth factor-β1 (TGF-β1), a mediator of skin wound healing. However, to our knowledge, no study has directly confirmed the efficacy of Chlorella vu...
Prosthetic mesh infection is a devastating complication of abdominal hernia repair which impairs natural healing in the implant area, leading to increased rates of patient morbidity, mortality, and prolonged hospitalization. This preclinical study wa...
Bone defects and complex fractures present significant challenges for orthopaedic surgeons. Current surgical procedures involve the reconstruction and mechanical stabilisation of complex fractures using metal hardware (i.e., wires, plates and screws)...
The aim was to assess the blending effect of universal-shade resin-based composites (RBCs) (Omnichroma—OC; Clearfil Majesty Universal–CM; Venus Pearl—V; Transcend—T) used for repair for lithium disilicate blocks. Fifteen paral...
Cycle slip (CS) is a primary error source in Precise Point Positioning/Inertial Navigation System (PPP/INS) integrated systems. In this study, an INS-aided CS detection and repair method is presented. It utilizes high-precision INS information instea...
Background: Symptomatic rotator cuff (RC) repair continues to be a complex issue. Leaving the long head of the biceps (LHB) in place might increase the risk of residual pain, even in the case of a healed RC. The purpose of this study was to assess th...
Residual stress has a three-dimensional scale effect (length, depth, and width) in the process of repair welding, which has a detrimental impact on the service of the aluminum alloy welded structures in high-speed trains. This paper aims to systemati...
INTRODUCTION. Recent neuroimaging studies suggest that dental loss replacements induce changes in neuroplasticity as well as in correlated connectivity between brain networks. However, as the typical temporal delay in detecting brain activity by neur...
DNA damage caused by exogenous or endogenous factors is a common challenge for developing fish embryos. DNA damage repair (DDR) pathways help organisms minimize adverse effects of DNA alterations. In terms of DNA repair mechanisms, sturgeons represen...
This study entailed performance tests to confirm the bond performance of the proposed new repair material and the pressurization effect of the developed mechanical pressurizing equipment. The physical property changes of the new repair material were...
Ovarian cancer (OC) is the seventh most common type of cancer in women worldwide. Treatment for OC usually involves a combination of surgery and chemotherapy with carboplatin and paclitaxel. Platinum-based agents exert their cytotoxic action through...
Cellular effects of ionizing radiation (IR) are of great variety and level, but they are mainly damaging since radiation can perturb all important components of the cell, from the membrane to the nucleus, due to alteration of different biological mol...
This study investigates adhesively bonded composite patch repair to enhance the load-carrying capacity of damaged metallic structures, introducing a novel FE-augmented machine learning (ML) framework that addresses the limited availability of experim...
Due to the excellent mechanical properties and heat resistance, bismaleimide matrix composite materials have been widely used in aircraft. However, they are susceptible to low-energy impacts, such as bird hits, gravel, tools falling, etc., which can...
Calcitonin gene-related peptide (CGRP) has 37 amino acids. Initially, CGRP had vasodilatory and nociceptive effects. As research progressed, evidence revealed that the peripheral nervous system is closely associated with bone metabolism, osteogenesis...
To achieve effective antioxidation of on-site repair coating for C/C brake materials in the full temperature range (500–900 °C), lead glass and bismuth glass were introduced into the borosilicate glass to acquire the protective coatings. Be...
In plant breeding, the ability to manipulate meiotic recombination aids in the efficient construction of new allelic compositions of chromosomes and facilitates gene transfer from wild relatives of crop plants. The DNA mismatch repair system antagoni...
Radiation resistance and radiation-related side effects warrant research into alternative strategies in the application of this modality to cancer treatment. Designed in silico to improve the pharmacokinetics and anti-cancer properties of 2-methoxyes...
Meniscus tissue engineering (MTE) has emerged as a promising strategy for meniscus repair and regeneration. As versatile platforms, hydrogels have gained significant attention in this field, as they possess tunable properties that allow them to mimic...
Thio- and cyano- modified single-stranded poly(dNTP) sequences of different molecular sizes (20–200 n) and the same lengths routine poly(dNTP) and poly(NTP) species were tested for their impact on catalytic activities of β-like DNA polymer...
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Plant-based ecological protection is one of the effective methods to improve the stability of slope soils. However, plants need a stable growth environment and water supply. Although it has been demonstrated that polymer materials can effectively enh...
Cured-In-Place-Pipe (CIPP) rehabilitation technology is widely utilized in pipeline rehabilitation projects and has exhibited favorable results. Nevertheless, the mechanical characteristics of pipelines after CIPP rehabilitation and the effectiveness...
Tyrosine kinase inhibitors (TKIs), such as sunitinib and sorafenib, are standard treatments for renal cell carcinoma (RCC). However, most patients treated with these drugs eventually develop drug resistance and relapse; therefore, new treatment optio...
The effects of low-dose radiation exposure remain a controversial topic in radiation biology. This study compares early (0.5, 4, 24, 48, and 72 h) and late (5, 10, and 15 cell passages) post-irradiation changes in γH2AX, 53BP1, pATM, and p-p53...
For a long time, the stem cell regenerative paradigm has been based on the assumption that progenitor cells play a critical role in tissue repair by means of their plasticity and differentiation potential. However, recent works suggest that the mecha...
There is a need to improve the effectiveness of radiotherapy (RT) in hepatocellular carcinoma (HCC). Therefore, the purpose of this study was to explore the efficacy and toxicity of the anti-microtubule agent Vinorelbine as a radiosensitizer in HCC....
Intergroup interaction, a pivotal aspect of social interaction, encompasses both cooperation and competition. Group identity significantly impacts individual behaviors and decision-making processes. This influence manifests in two contrasting ways wh...
Unsaturated polyester polymer concrete (UPPC) is a promising rapid repair material for pavement engineering, while the age-dependent and rate-dependent bonding behaviors between UPPC and ordinary Portland concrete (OPC) substrate remains poorly under...
With the large-scale application of lithium-ion batteries in the field of new energy, many retired lithium batteries not only cause environmental pollution problems but also lead to serious waste of resources. Repairing failed lithium batteries and r...
Effective pavement repair planning is vital for sustaining performance and minimizing lifecycle costs. At the network level, most agencies still rely on deterministic repair-effect assumptions, where repair outcomes are defined by fixed restoration v...
Background: Gamma Knife radiosurgery (GKS) delivers highly conformal intracranial irradiation, yet clinical decision-making still relies predominantly on physical dose metrics that do not account for fractionation, dose rate, treatment time, or DNA r...
Shape memory alloy (SMA), a type of smart material, is widely used in the design of reinforcement and repair, isolation, and shock absorption of building structures because of its outstanding characteristics, such as the shape memory effect (SME), su...
Background: Cuff reconstructions vary due to different technical approaches by suture anchor manufacturers, as well as different suture construct configurations. Objectives: The main aim of this study is to primarily compare clinical outcomes and sec...
According to the present knowledge, this is the first report on establishing transformed root cultures of Leonotis nepetifolia after Rhizobium rhizogenes-mediated transformation. The preliminary phytochemical analysis showed differences in the conten...
The structural damage repair of composite material is an important issue that needs to be addressed during the service life of composite materials. To investigate the effects of a scarf structure and scarf angle on the repair quality of composite mat...
During the accelerated transition toward greener and more decarbonized development, urban regeneration initiatives have emerged as an important policy instrument for enhancing the synergistic effect of pollution and carbon reduction (SEPCR). Using pa...
Sebacic acid (SA), a ten-carbon medium-chain dicarboxylic acid, has emerged as a multifunctional bioactive metabolite with potential applications in metabolic regulation and regenerative medicine. Evidence indicates that SA exerts anti-inflammatory e...
Jinan City in China is known for its abundant spring water, and the protection of underground spring water transport channels is a key issue that needs to be paid attention to in Jinan subway construction. In areas where underground spring water tran...
Automation and autonomous systems are quickly becoming a more engrained aspect of modern society. The need for effective, secure computer code in a timely manner has led to the creation of automated code repair techniques to resolve issues quickly. H...
(1) Background: Pretreatment by Rad51-inhibitory substances such as gemcitabine followed by arterial chemotherapy using antineoplastic agents causing DNA crosslink might be more beneficial for patients with locally advanced pancreatic cancers than co...
Ischaemic cardiac disease is associated with a loss of cardiomyocytes and an intrinsic lack of myocardial renewal. Recent work has shown that the heart retains limited cardiomyocyte proliferation, which remains inefficient when facing pathological co...
In this work the effectiveness of stepped repairs to damaged fiber reinforced composite materials is investigated by using previously validated numerical models which were compared with tested repaired composite plates. Parametric studies were carrie...
Background: Aggressive and metastatic PitNETs are challenging conditions. Immune checkpoint inhibitors (ICIs) are currently considered in cases resistant to temozolomide (TMZ). However, clinical experience is essentially limited to case reports, with...
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