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22,092 Results Found

  • Article
  • Open Access
11 Citations
4,140 Views
15 Pages

1 October 2021

(1) Background: The empowerment of women contributes to better child health and wellness. This study aimed to examine the association between women’s empowerment and complete vaccination of children, as recommended in the National Expanded Program on...

  • Article
  • Open Access
3 Citations
2,165 Views
16 Pages

A QoS Prediction Approach Based on Truncated Nuclear Norm Low-Rank Tensor Completion

  • Hong Xia,
  • Qingyi Dong,
  • Jiahao Zheng,
  • Yanping Chen,
  • Cong Gao and
  • Zhongmin Wang

20 August 2022

With the rise of mobile edge computing (MEC), mobile services with the same or similar functions are gradually increasing. Usually, Quality of Service (QoS) has become an indicator to measure high-quality services. In the real MEC service invocation...

  • Article
  • Open Access
3 Citations
2,050 Views
23 Pages

Immunization with Complete Freund’s Adjuvant Reveals Trained Immunity-like Features in A/J Mice

  • Kiruthiga Mone,
  • Shraddha Singh,
  • Fatema Abdullatif,
  • Meghna Sur,
  • Mahima T. Rasquinha,
  • Javier Seravalli,
  • Denise K. Zinniel,
  • Indranil Mukhopadhyay,
  • Raul G. Barletta and
  • Teklab Gebregiworgis
  • + 1 author

21 July 2025

Background/Objectives: Freund’s adjuvants induce different immunomodulatory effects, but their underlying molecular mechanisms are unclear. In this study, we investigated whether the immune-stimulating effects of the complete Freund’s adj...

  • Article
  • Open Access
30 Citations
6,034 Views
13 Pages

8 January 2021

The prevalence of Parkinson’s disease increases a tremendous medical and economic burden to society. Therefore, the effective drugs are urgently required. However, the traditional development of effective drugs is costly and risky. Drug repurpo...

  • Article
  • Open Access
8 Citations
3,919 Views
11 Pages

Diacetylcurcumin: Its Potential Antiarthritic Effect on a Freund’s Complete Adjuvant-Induced Murine Model

  • Carolina Escobedo-Martínez,
  • Silvia Laura Guzmán-Gutiérrez,
  • María Isabel Carrillo-López,
  • Martha Alicia Deveze-Álvarez,
  • Alfonso Trujillo-Valdivia,
  • William Meza-Morales and
  • Raúl G. Enríquez

21 July 2019

The present study aims to evaluate the antiarthritic activity of diacetylcurcumin (DAC), a synthetic derivative where the free phenolic groups of curcumin are derivatized by acetylation, thereby conferring greater lipophilicity to the parent molecule...

  • Article
  • Open Access
4 Citations
3,431 Views
12 Pages

4 February 2023

Osteoarthritis (OA) is a common disorder that can affect any joint in the human body. This study aimed to examine the anti-arthritic properties of high and low doses of grapefruit juice (GFJ), as grapefruit appears to contain anti-inflammatory bioche...

  • Proceeding Paper
  • Open Access
1,347 Views
6 Pages

The aim of this paper is to review the most important properties and applications of the complete hypergroups. We will focus on the reversibility, regularity and reducibility properties, on the class equation and the commutativity degree of the compl...

  • Article
  • Open Access
11 Citations
3,755 Views
9 Pages

Clinical Prognostic Factors Associated with Good Outcomes in Pediatric Bell’s Palsy

  • Myung Chul Yoo,
  • Dong Choon Park,
  • Jae Yong Byun and
  • Seung Geun Yeo

24 September 2021

The prognosis of children with Bell’s palsy remains unclear due to its relatively low incidence, and thus, the small number of patients included in individual studies. To evaluate the prognosis of children with Bell’s palsy and identify the predictiv...

  • Article
  • Open Access
3 Citations
2,068 Views
8 Pages

13 December 2022

We prove that the function σ(s) defined by β(s)=6s2+12s+53s2(2s+3)−ψ′(s)2−σ(s)2s5,s>0, is strictly increasing with the sharp bounds 0<σ(s)<49120, where β(s) is Nielsen’s beta function a...

  • Tutorial
  • Open Access
5 Citations
3,777 Views
19 Pages

Gauge Dependence of the Gauge Boson Projector

  • Priidik Gallagher,
  • Stefan Groote and
  • Maria Naeem

28 July 2020

The propagator of a gauge boson, like the massless photon or the massive vector bosons W± and Z of the electroweak theory, can be derived in two different ways, namely via Green’s functions (semi-classical approach) or via the vacuum exp...

  • Article
  • Open Access
3,620 Views
10 Pages

On the Semigroup Whose Elements Are Subgraphs of a Complete Graph

  • Yanisa Chaiya,
  • Chollawat Pookpienlert,
  • Nuttawoot Nupo and
  • Sayan Panma

Let K n be a complete graph on n vertices. Denote by S K n the set of all subgraphs of K n . For each G , H ∈ S K n , the ring sum of G and H is a graph whose vertex set is V ( G ) ∪ V ( H ) and whose edges...

  • Article
  • Open Access
1,624 Views
15 Pages

22 August 2025

For decades, the U.S. college admissions process has utilized standardized exams as critical indicators of college readiness. With the onset of the COVID pandemic, the majority of 4-year universities implemented the Test-Optional policy to improve co...

  • Feature Paper
  • Article
  • Open Access
755 Views
34 Pages

30 October 2025

Tarski’s first-order axiom system E2 for Euclidean geometry is notable for its completeness and decidability. However, the Pythagorean theorem—either in its modern algebraic form a2+b2=c2 or in Euclid’s Elements—cannot be dire...

  • Case Report
  • Open Access
2,459 Views
8 Pages

Transient Third-Degree Atrioventricular Block in a Dog with Addisonian Crisis

  • Paula Maria Pașca,
  • Gheorghe Solcan,
  • Andrei Blageanu,
  • Caroline Maria Lăcătuș,
  • Petru Cosmin Peștean,
  • Constantin Adrian Stancu and
  • Andrei Radu Baisan

16 January 2025

A 3-year-old spayed male mixed-breed Labrador presented to the Emergency and Critical Care Unit with lethargy, loss of appetite, vomiting, a recent history of presyncopal episodes, and severe exercise intolerance. On admission, the patient had bradyc...

  • Article
  • Open Access
6 Citations
2,142 Views
10 Pages

On the Fixed Point Theorem for Large Contraction Mappings with Applications to Delay Fractional Differential Equations

  • Mouataz Billah Mesmouli,
  • Elvan Akın,
  • Loredana Florentina Iambor,
  • Osman Tunç and
  • Taher S. Hassan

This paper explores a new class of mappings and presents several fixed-point results for these mappings. We define these mappings by combining well-known mappings in the literature, specifically the large contraction mapping and Chatterjea’s ma...

  • Article
  • Open Access
43 Citations
7,839 Views
18 Pages

Vehicle detection is essential for driverless systems. However, the current single sensor detection mode is no longer sufficient in complex and changing traffic environments. Therefore, this paper combines camera and light detection and ranging (LiDA...

  • Feature Paper
  • Article
  • Open Access
160 Views
43 Pages

12 December 2025

In this work, a hypothesis is studied as to whether different DoS attacks affect the parameters of voice and video streams, as well as performance, on three different VoIP platforms. This research is a continuation of a previous work, which studied t...

  • Review
  • Open Access
3 Citations
6,041 Views
28 Pages

1 July 2020

In this work the complete version of Stirling’s formula, which is composed of the standard terms and an infinite asymptotic series, is used to obtain exact values of the logarithm of the gamma function over all branches of the complex plane. Exact va...

  • Article
  • Open Access
51 Citations
4,990 Views
13 Pages

1 February 2019

Influenced by the complexity of ocean environmental noise and the time-varying of underwater acoustic channels, feature extraction of underwater acoustic signals has always been a difficult challenge. To solve this dilemma, this paper introduces a hy...

  • Article
  • Open Access
1 Citations
1,668 Views
13 Pages

Some Rational Approximations and Bounds for Bateman’s G-Function

  • Omelsaad Ahfaf,
  • Mansour Mahmoud and
  • Ahmed Talat

2 May 2022

Symmetrical patterns exist in the nature of inequalities, which play a basic role in theoretical and applied mathematics. In several studies, inequalities present accurate approximations of functions based on their symmetry properties. In this paper,...

  • Article
  • Open Access
3 Citations
3,023 Views
13 Pages

29 October 2021

Our recent study demonstrated that the CC-chemokine ligand 2 (CCL2) present in primary afferent fibers (PAFs) plays an important role in the microglia-dependent neuronal activation associated with zymosan-induced inflammatory pain. The present study...

  • Communication
  • Open Access
777 Views
11 Pages

Sex-Related Anti-Nociceptive Activity of a Flavonoid-Based Formulated Extract from Citrus Peels (Gold Lotion): New Insights into a Rat Model

  • Alessandro Di Cerbo,
  • Mario Nicotra,
  • Michiko Suzawa,
  • Tommaso Iannitti and
  • Julio Cesar Morales-Medina

19 August 2025

Inflammatory pain is a worldwide health problem, affecting primarily women. Nonetheless, most research conducted in this field has involved male subjects, and only 10% of the results have been obtained using females. Gold Lotion (GL) is a formulated...

  • Article
  • Open Access
2 Citations
1,805 Views
12 Pages

On Modular b-Metrics

  • Salvador Romaguera

9 October 2024

The notions of modular b-metric and modular b-metric space were introduced by Ege and Alaca as natural generalizations of the well-known and featured concepts of modular metric and modular metric space presented and discussed by Chistyakov. In partic...

  • Article
  • Open Access
10 Citations
4,092 Views
18 Pages

Analgesic Effects and Impairment in Locomotor Activity Induced by Cannabinoid/Opioid Combinations in Rat Models of Chronic Pain

  • Mohammad Alsalem,
  • Ahmad Altarifi,
  • Mansour Haddad,
  • Belal Azab,
  • Heba Kalbouneh,
  • Amer Imraish,
  • Tareq Saleh and
  • Khalid El-Salem

Both opioids and cannabinoids have well-known antinociceptive effects in different animal models of chronic pain. However, unwanted side effects limit their use. The aim of this study is to evaluate the antinociceptive effect of combining synthetic c...

  • Article
  • Open Access
2 Citations
3,194 Views
20 Pages

Discovery, Pathogenesis, and Complete Genome Characterization of Lates calcarifer Herpesvirus

  • Bartjan Simmelink,
  • Jordy P. M. Coolen,
  • Wannes Vogels,
  • Martin Deijs,
  • Jessica L. M. van der Last-Kempkes,
  • Kah Sing Ng,
  • Siow Foong Chang,
  • Koen Gevers,
  • Liesbeth Harkema and
  • Lia van der Hoek
  • + 1 author

20 February 2024

In 2015 and 2016, two Barramundi (Lates calcarifer) farms in Singapore reported a disease outbreak characterized by lethargic behavior, pronounced inappetence, generalized skin lesions, erosions of the fins and tail, and ultimately high mortality in...

  • Article
  • Open Access
24 Citations
6,395 Views
16 Pages

Calotropis procera (commonly known as Swallow wort) is described in the Ayurvedic literature for the treatment of inflammation and arthritic disorders. Therefore, in the present work, the antiarthritic activity of potential fractions of Swallow wort...

  • Article
  • Open Access
3 Citations
4,687 Views
16 Pages

Anti-Inflammatory Property Establishment of Fulvic Acid Transdermal Patch in Animal Model

  • Maria A. Konnova,
  • Alexander A. Volkov,
  • Anna G. Solovyeva,
  • Peter V. Peretyagin and
  • Nina B. Melnikova

26 September 2023

The formulation of the transdermal patch with fulvic acid (FA) on an emulsion basis using pluronic Kolliphor® p237 as a permeability enhancer was developed and studied for anti-inflammatory properties. FA was isolated from the peat in the Nizhny...

  • Article
  • Open Access
15 Citations
2,657 Views
15 Pages

A Metabolomic Study of the Analgesic Effect of Lappaconitine Hydrobromide (LAH) on Inflammatory Pain

  • Xu Li,
  • Xueqi Wang,
  • Zhengdou Li,
  • Ying Mao,
  • Zhao Liu,
  • Xiaoxiao Liu,
  • Xinliang Zhu and
  • Ji Zhang

29 September 2022

Lappaconitine (LA) is a C-18 diterpene alkaloid isolated from Aconitum sinomontanum Nakai that has been shown to relieve mild to moderate discomfort. Various researchers have tried to explain the underlying mechanism of LA’s effects on chronic...

  • Article
  • Open Access
20 Citations
3,919 Views
12 Pages

15 June 2021

Unlike other widely known Aloe species used for treatment of rheumatoid arthritis, this species suffers from a lack of sufficient studies on its biological and chemical characters. This is what drove us to perform this work to evaluate the in vivo an...

  • Article
  • Open Access
7 Citations
2,188 Views
30 Pages

The effective defense of sparsely populated border islands, surrounded by a multifaceted sea, against enemy infiltration poses a crucial problem in national defense. One possible solution is to deploy multiple unmanned surface vessels (USVs) to form...

  • Article
  • Open Access
15 Citations
4,863 Views
13 Pages

Antinociceptive and Abuse Potential Effects of Cannabinoid/Opioid Combinations in a Chronic Pain Model in Rats

  • Mohammad Alsalem,
  • Ahmad Altarifi,
  • Mansour Haddad,
  • Sara A. Aldossary,
  • Heba Kalbouneh,
  • Nour Aldaoud,
  • Tareq Saleh and
  • Khalid El-Salem

17 November 2019

Chronic pain is a persistent and debilitating health problem. Although the use of analgesics such as opioids is useful in mitigating pain, their prolonged use is associated with unwanted effects including abuse liability. This study assesses the anti...

  • Article
  • Open Access
3 Citations
3,158 Views
16 Pages

Evidence for Endogenous Opioid Dependence Related to Latent Sensitization in a Rat Model of Chronic Inflammatory Pain

  • Julio César Morales-Medina,
  • Nicola Pugliese,
  • Alessandro Di Cerbo,
  • Claudia Zizzadoro and
  • Tommaso Iannitti

1 February 2023

Studies performed in a mouse model of chronic inflammatory pain induced by intraplantar injection of complete Freund’s adjuvant (CFA) have shown that constitutive activation of the endogenous opioid signaling, besides serving as a mechanism of...

  • Article
  • Open Access
2 Citations
1,809 Views
14 Pages

Can Botulinum Toxin Type E Serve as a Novel Therapeutic Target for Managing Chronic Orofacial Pain?

  • Sung-Koog Jung,
  • Yu-Mi Kim,
  • Min-Jeong Jo,
  • Jo-Young Son,
  • Jin-Sook Ju,
  • Min-Kyoung Park,
  • Min-Kyung Lee,
  • Jae-Young Kim,
  • Jeong-Sun Nam and
  • Dong-Kuk Ahn

10 March 2025

The existing literature offers limited experimental evidence on the role of botulinum neurotoxin type E (BoNT-E) in pain transmission. The present study investigated the antinociceptive effects of subcutaneously administered BoNT-E in chronic orofaci...

  • Article
  • Open Access
1 Citations
2,915 Views
16 Pages

Assessing the Impact of Influenza Vaccination Timing on Experimental Arthritis: Effects on Disease Progression and Inflammatory Biomarkers

  • Vera Tarjányi,
  • Ákos Ménes,
  • Leila Hamid,
  • Andrea Kurucz,
  • Dániel Priksz,
  • Balázs Varga,
  • Rudolf Gesztelyi,
  • Rita Kiss,
  • Ádám István Horváth and
  • Nikolett Szentes
  • + 3 authors

Numerous studies have indicated a link between vaccines and the exacerbation of autoimmune diseases including rheumatoid arthritis (RA). However, there is no consensus in clinical practice regarding the optimal timing of immunization. Therefore, this...

  • Article
  • Open Access
22 Citations
4,849 Views
20 Pages

Hemokinin-1 Gene Expression Is Upregulated in Trigeminal Ganglia in an Inflammatory Orofacial Pain Model: Potential Role in Peripheral Sensitization

  • Timea Aczél,
  • Angéla Kecskés,
  • József Kun,
  • Kálmán Szenthe,
  • Ferenc Bánáti,
  • Susan Szathmary,
  • Róbert Herczeg,
  • Péter Urbán,
  • Attila Gyenesei and
  • Balázs Gaszner
  • + 2 authors

A large percentage of primary sensory neurons in the trigeminal ganglia (TG) contain neuropeptides such as tachykinins or calcitonin gene-related peptide. Neuropeptides released from the central terminals of primary afferents sensitize the secondary...

  • Article
  • Open Access
1 Citations
1,264 Views
19 Pages

Association Between Cardiovascular Disease and Complete Edentulism in U.S. Adults

  • Saud Alyahya,
  • Basel Hamoud,
  • Ali Alqattan,
  • Masoud Almasoud,
  • Yousef Almehjan,
  • Rashed Alajmi,
  • Hesham Alhazmi and
  • Hend Alqaderi

26 August 2025

(1) Background: Cardiovascular disease (CVD) and edentulism are major public health challenges with shared risk factors and overlapping inflammatory pathways. This study investigates the association between complete tooth loss and CVD. (2) Methods: D...

  • Article
  • Open Access
1 Citations
1,710 Views
17 Pages

Coincidence Theorems under Generalized Nonlinear Relational Contractions

  • Nifeen Hussain Altaweel,
  • Nidal H. E. Eljaneid,
  • Hamid I. A. Mohammed,
  • Ibtisam M. Alanazi and
  • Faizan Ahmad Khan

6 February 2023

After the appearance of relation-theoretic contraction principle due to Alam and Imdad, the domain of fixed point theory applied to relational metric spaces has attracted much attention. Existence and uniqueness of fixed/coincidence points satisfying...

  • Article
  • Open Access
2 Citations
2,267 Views
14 Pages

Existence and Unique Coupled Solution in Sb-Metric Spaces by Rational Contraction with Application

  • Jelena Vujaković,
  • Gajula Naveen Venkata Kishore,
  • Konduru Pandu Ranga Rao,
  • Stojan Radenović and
  • Shaik Sadik

28 March 2019

In this paper, we prove a unique common coupled fixed point theorem for two pairs of w-compatible mappings in S b -metric spaces. We also furnish an example to support our main result.

  • Article
  • Open Access
407 Views
20 Pages

Association Between Complete Blood Count and the Lipoxygenase Pathway in Hashimoto’s Thyroiditis

  • Karolina Wrońska,
  • Maciej Ziętek,
  • Tomasz Machałowski and
  • Małgorzata Szczuko

5 December 2025

Background: Hashimoto’s Thyroiditis (HT) is one of the most common autoimmune diseases worldwide, yet little is known about the role of lipid mediators in its pathogenesis. This study investigated whether there is a link between complete blood...

  • Brief Report
  • Open Access
1 Citations
2,157 Views
9 Pages

In this study, we document the first recorded range extension of the genus Synaphobranchus from the East Mariana Basin in the Western Pacific Ocean. We sequenced the complete mitochondrial (mt) genome of two deep-sea eels (Synaphobranchus brevidorsal...

  • Article
  • Open Access
7 Citations
2,157 Views
14 Pages

26 February 2023

Nuthatches (genus Sitta; family Sittidae) are a passerine genus with a predominantly Nearctic and Eurasian distribution. To understand the phylogenetic position of Sitta and phylogenetic relations within this genus, we sequenced the complete mitochon...

  • Article
  • Open Access
4,283 Views
14 Pages

24 June 2021

In discussing the arrival of Buddhism to China, Erik Zürcher describes the meeting of “a jungle of Buddhist metaphysics” with other local philosophies and practices. This period was a transformative encounter with wide-ranging ramifications, includin...

  • Article
  • Open Access
2 Citations
3,474 Views
11 Pages

21 August 2023

Bacteria in the genus Elizabethkingia have emerged as a cause of life-threatening infections in humans. However, accurate species identification of these pathogens relies on molecular techniques. We aimed to evaluate the accuracy of 16S rRNA and comp...

  • Article
  • Open Access
4 Citations
3,237 Views
19 Pages

Targeted Therapy for Glomerulonephritis Using Arterial Delivery of Encapsulated Etanercept

  • Natalia A. Shushunova,
  • Oksana A. Mayorova,
  • Ekaterina S. Prikhozhdenko,
  • Olga A. Goryacheva,
  • Oleg A. Kulikov,
  • Valentina O. Plastun,
  • Olga I. Gusliakova,
  • Albert R. Muslimov,
  • Olga A. Inozemtseva and
  • Nikolay A. Pyataev
  • + 4 authors

1 February 2023

Complex immunosuppressive therapy is prescribed in medical practice to patients with glomerulonephritis to help them overcome symptoms and prevent chronic renal failure. Such an approach requires long-term systemic administration of strong medication...

  • Article
  • Open Access
7 Citations
2,551 Views
7 Pages

3 January 2022

We solve a question posed by E. Karapinar, F. Khojasteh and Z.D. Mitrović in their paper “A Proposal for Revisiting Banach and Caristi Type Theorems in b-Metric Spaces”. We also characterize the completeness of b-metric spaces with t...

  • Article
  • Open Access
1 Citations
2,530 Views
11 Pages

2 January 2020

This paper gives the new concepts of quasi ( s , r ) -contractive multi-valued operators and establishes some related fixed point results for such operators. In addition, an application to certain functional equations arising from dynamic prog...

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