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200 Results Found

  • Article
  • Open Access
8 Citations
5,374 Views
18 Pages

Today Deep Learning (DL) is state-of-the-art in medical imaging segmentation tasks, including accurate localization of abdominal organs in MRI images. But segmentation still exhibits inaccuracies, which may be due to texture similarities, proximity o...

  • Article
  • Open Access
20 Citations
4,269 Views
17 Pages

Deep Learning-Based Post-Processing of Real-Time MRI to Assess and Quantify Dynamic Wrist Movement in Health and Disease

  • Karl Ludger Radke,
  • Lena Marie Wollschläger,
  • Sven Nebelung,
  • Daniel Benjamin Abrar and ,
  • Christoph Schleich,
  • Matthias Boschheidgen,
  • Miriam Frenken,
  • Justus Schock,
  • Dirk Klee and
  • Anja Müller-Lutz
  • + 9 authors+ 4 authors

While morphologic magnetic resonance imaging (MRI) is the imaging modality of choice for the evaluation of ligamentous wrist injuries, it is merely static and incapable of diagnosing dynamic wrist instability. Based on real-time MRI and algorithm-bas...

(This article belongs to the Special Issue Advanced MRI Techniques for Musculoskeletal Imaging)
  • Article
  • Open Access
8 Citations
5,263 Views
24 Pages

21 August 2025

Accurate and timely detection of brain tumors from magnetic resonance imaging (MRI) scans is critical for improving patient outcomes and informing therapeutic decision-making. However, the complex heterogeneity of tumor morphology, scarcity of annota...

(This article belongs to the Topic Machine Learning and Deep Learning in Medical Imaging)
  • Case Report
  • Open Access
3 Citations
2,383 Views
7 Pages

Changes in Brain Volumes Are Relevant during Natalizumab-Associated Progressive Multifocal Leukoencephalopathy: Lessons from a Case Report

  • Roberto De Masi,
  • Stefania Orlando,
  • Silvia Armenise,
  • Pantaleo Spagnolo and ,
  • Ruggero Capra and
  • Maria Carmela Costa
  • + 1 author+ 0 author

7 November 2022

This is a case report concerning a Natalizumab-associated Progressive Multifocal Leukoencephalopathy (PML) with cerebellar localization and wakefulness disturbances. Awakening and clinical improvement dramatically occurred as soon as the immune recon...

(This article belongs to the Special Issue State-of-the-Art Molecular Neurobiology in Italy)
  • Article
  • Open Access
2 Citations
2,018 Views
15 Pages

An Improved Postprocessing Method to Mitigate the Macroscopic Cross-Slice B0 Field Effect on R2* Measurements in the Mouse Brain at 7T

  • Chu-Yu Lee,
  • Daniel R. Thedens,
  • Olivia Lullmann,
  • Emily J. Steinbach and ,
  • Michelle R. Tamplin,
  • Michael S. Petronek,
  • Isabella M. Grumbach,
  • Bryan G. Allen,
  • Lyndsay A. Harshman and
  • Vincent A. Magnotta
  • + 5 authors+ 0 author

11 July 2024

The MR transverse relaxation rate, R2*, has been widely used to detect iron and myelin content in tissue. However, it is also sensitive to macroscopic B0 inhomogeneities. One approach to correct for the B0 effect is to fit gradient-echo signals with...

(This article belongs to the Section Neuroimaging)
  • Article
  • Open Access
3 Citations
4,412 Views
16 Pages

29 July 2024

Determining visual attention during cognitive tasks using activation MRI remains challenging. This study aimed to develop a new eye-tracking (ET) post-processing platform to enhance data accuracy, validate the feasibility of subsequent ET-fMRI applic...

(This article belongs to the Section Biomedical Sensors)
  • Article
  • Open Access
3 Citations
3,368 Views
11 Pages

14 April 2023

Gd- and Fe-based contrast agents reduce T1 and T2 relaxation times, respectively, are frequently used in MRI, providing improved cancer detection. Recently, contrast agents changing both T1/T2 times, based on core/shell nanoparticles, have been intro...

  • Article
  • Open Access
5 Citations
4,489 Views
14 Pages

Post-Processing Bias Field Inhomogeneity Correction for Assessing Background Parenchymal Enhancement on Breast MRI as a Quantitative Marker of Treatment Response

  • Alex Anh-Tu Nguyen,
  • Natsuko Onishi,
  • Julia Carmona-Bozo,
  • Wen Li and ,
  • John Kornak,
  • David C. Newitt and
  • Nola M. Hylton
  • + 2 authors+ 0 author

22 March 2022

Background parenchymal enhancement (BPE) of breast fibroglandular tissue (FGT) in dynamic contrast-enhanced breast magnetic resonance imaging (MRI) has shown an association with response to neoadjuvant chemotherapy (NAC) in patients with breast cance...

(This article belongs to the Special Issue Quantitative Imaging Network)
  • Article
  • Open Access
1,477 Views
14 Pages

Illuminating the Intricacies: A Comparative Cross-Sectional Sonographic Evaluation of Degenerative Changes in Leiomyomas Through Post-Processing Technique

  • Mahasin G. Hassan,
  • Nouf Aldrees,
  • Sadeem Aldawsari,
  • Raghad Alanazi and ,
  • Noura Alboqami,
  • Maryem Alanazi,
  • Renad Alanazi,
  • Khadejah Alrashidi and
  • Basim S. Almutairi
  • + 4 authors+ 0 author

21 November 2025

Background: Leiomyomas are benign tumors that may cause symptoms and affect fertility, requiring careful assessment. Magnetic Resonance Imaging (MRI) becomes crucial when ultrasonography results are inconclusive; however, it is expensive and time-con...

(This article belongs to the Special Issue Advanced Ultrasound Techniques in Diagnosis)
  • Article
  • Open Access
2 Citations
3,370 Views
15 Pages

Bone segmentation in magnetic resonance imaging (MRI) is crucial for clinical and research applications, including diagnosis, surgical planning, and treatment monitoring. However, it remains challenging due to anatomical variability and complex bone...

  • Technical Note
  • Open Access
3 Citations
3,502 Views
13 Pages

Quantitative Susceptibility Mapping: Translating an Investigative Research Tool into High Volume Clinical Diagnostic Imaging

  • Matthew T. Borzage,
  • Eamon K. Doyle,
  • Chia-Shang J. Liu,
  • Marvin D. Nelson and ,
  • Stefan Blüml,
  • John C. Wood and
  • Benita Tamrazi
  • + 2 authors+ 0 author

26 November 2022

Quantitative susceptibility mapping (QSM) is an MRI-based technique for iron quantification of targeted tissue. QSM provides information relevant to clinicians in a broad range of diagnostic contexts, including sickle cell disease, inflammatory/demye...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
1 Citations
3,465 Views
7 Pages

18 December 2021

Magnetic resonance imaging (MRI) integrates a static magnetic field, a time-varying gradient magnetic field at kHz and a radio-frequency (RF) magnetic field for non-invasive and real-time imaging; meanwhile, diffusion MRI (dMRI) pushes a further and...

(This article belongs to the Section Biomedical Engineering)
  • Article
  • Open Access
1,647 Views
14 Pages

Use of Patient-Specific 3D Models in Paediatric Surgery: Effect on Communication and Surgical Management

  • Cécile O. Muller,
  • Lydia Helbling,
  • Theodoros Xydias,
  • Jeanette Greiner and ,
  • Valérie Oesch,
  • Henrik Köhler,
  • Tim Ohletz and
  • Jatta Berberat
  • + 3 authors+ 0 author

26 January 2026

Children with rare tumours and malformations may benefit from innovative imaging, including patient-specific 3D models that can enhance communication and surgical planning. The primary aim was to evaluate the impact of patient-specific 3D models on c...

(This article belongs to the Special Issue 3D Image Processing: Progress and Challenges)
  • Article
  • Open Access
2,450 Views
14 Pages

5 November 2022

Brain tumors are abnormal cell growth in the brain tissues that can be cancerous or not. In any case, they could be a very aggressive disease that should be detected as early as possible. Usually, magnetic resonance imaging (MRI) is the main tool com...

  • Perspective
  • Open Access
13 Citations
6,450 Views
28 Pages

Methodological Considerations for Neuroimaging in Deep Brain Stimulation of the Subthalamic Nucleus in Parkinson’s Disease Patients

  • Bethany R. Isaacs,
  • Max C. Keuken,
  • Anneke Alkemade,
  • Yasin Temel and ,
  • Pierre-Louis Bazin and
  • Birte U. Forstmann
  • + 1 author+ 0 author

27 September 2020

Deep brain stimulation (DBS) of the subthalamic nucleus is a neurosurgical intervention for Parkinson’s disease patients who no longer appropriately respond to drug treatments. A small fraction of patients will fail to respond to DBS, develop p...

(This article belongs to the Special Issue Trends in Clinical Deep Brain Stimulation)
  • Review
  • Open Access
24 Citations
10,577 Views
18 Pages

Brain Magnetic Resonance Imaging in Wilson’s Disease—Significance and Practical Aspects—A Narrative Review

  • Tomasz Litwin,
  • Barbara Rędzia-Ogrodnik,
  • Agnieszka Antos,
  • Adam Przybyłkowski and ,
  • Anna Członkowska and
  • Jan Paweł Bembenek
  • + 1 author+ 0 author

Wilson’s disease (WD) is a genetic disorder of copper metabolism with pathological copper accumulation in many organs, resulting in clinical symptoms, mostly hepatic and neuropsychiatric. As copper accumulates in the brain during WD, and almost...

(This article belongs to the Special Issue Brain Magnetic Resonance Imaging in Neurological Disorders)
  • Article
  • Open Access
1 Citations
3,851 Views
12 Pages

Post-Acquisition Hyperpolarized 29Silicon Magnetic Resonance Image Processing for Visualization of Colorectal Lesions Using a User-Friendly Graphical Interface

  • Caitlin V. McCowan,
  • Duncan Salmon,
  • Jingzhe Hu,
  • Shivanand Pudakalakatti and ,
  • Nicholas Whiting,
  • Jennifer S. Davis,
  • Daniel D. Carson,
  • Niki M. Zacharias,
  • Pratip K. Bhattacharya and
  • Mary C. Farach-Carson
  • + 5 authors+ 0 author

Medical imaging devices often use automated processing that creates and displays a self-normalized image. When improperly executed, normalization can misrepresent information or result in an inaccurate analysis. In the case of diagnostic imaging, a f...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
53 Views
14 Pages

Non-Contrast Magnetic Resonance Lymphography: Technical Approach Toward Protocol Standardization

  • Theodoros Chrelias,
  • Evangelos Dimakakos,
  • Konstantinos Samiotis,
  • Kalliopi Varaki and ,
  • Margarita Toumanidou,
  • Kyriaki Cholidou,
  • Urska Bregar,
  • Peter Marschang,
  • Chris Manu and
  • Nikolaos Papadopoulos
  • + 7 authors+ 2 authors

4 November 2026

Background: Lymphedema is a chronic condition for which accurate imaging evaluation of the lymphatic system can contribute to diagnosis, disease assessment, and treatment planning. Non-contrast magnetic resonance lymphangiography (NCMRL) is an imagin...

(This article belongs to the Special Issue European Independent Foundation in Angiology/Vascular Medicine (VAS) Collection on Vascular Medicine: 2nd Edition)
  • Review
  • Open Access
21 Citations
4,148 Views
16 Pages

Artificial Intelligence and Radiomics for Endometrial Cancer MRI: Exploring the Whats, Whys and Hows

  • Elisabetta Leo,
  • Arnaldo Stanzione,
  • Mariaelena Miele,
  • Renato Cuocolo and ,
  • Giacomo Sica,
  • Mariano Scaglione,
  • Luigi Camera,
  • Simone Maurea and
  • Pier Paolo Mainenti
  • + 4 authors+ 0 author

30 December 2023

Endometrial cancer (EC) is intricately linked to obesity and diabetes, which are widespread risk factors. Medical imaging, especially magnetic resonance imaging (MRI), plays a major role in EC assessment, particularly for disease staging. However, th...

(This article belongs to the Section Nuclear Medicine & Radiology)
  • Review
  • Open Access
1,329 Views
20 Pages

3 December 2025

Cine (dynamic) MRI is a non-invasive MRI technique that captures moving images and can be valuable in evaluating inflammatory bowel disease (IBD). This sequence shows emerging potential in providing functional data to assess bowel motility patterns,...

(This article belongs to the Section Pathology and Molecular Diagnostics)
  • Article
  • Open Access
2 Citations
3,361 Views
19 Pages

Enhancing Knee MR Image Clarity through Image Domain Super-Resolution Reconstruction

  • Vishal Patel,
  • Alan Wang,
  • Andrew Paul Monk and
  • Marco Tien-Yueh Schneider

This study introduces a hybrid analytical super-resolution (SR) pipeline aimed at enhancing the resolution of medical magnetic resonance imaging (MRI) scans. The primary objective is to overcome the limitations of clinical MRI resolution without the...

(This article belongs to the Special Issue Recent Progress in Biomedical Image Processing)
  • Article
  • Open Access
10 Citations
5,990 Views
20 Pages

3D Quantitative-Amplified Magnetic Resonance Imaging (3D q-aMRI)

  • Itamar Terem,
  • Kyan Younes,
  • Nan Wang,
  • Paul Condron and ,
  • Javid Abderezaei,
  • Haribalan Kumar,
  • Hillary Vossler,
  • Eryn Kwon,
  • Mehmet Kurt and
  • Kawin Setsompop
  • + 7 authors+ 2 authors

Amplified MRI (aMRI) is a promising new technique that can visualize pulsatile brain tissue motion by amplifying sub-voxel motion in cine MRI data, but it lacks the ability to quantify the sub-voxel motion field in physical units. Here, we introduce...

(This article belongs to the Special Issue Novel MRI Techniques and Biomedical Image Processing)
  • Article
  • Open Access
6 Citations
3,421 Views
9 Pages

Ultrashort Echo Time and Fast Field Echo Imaging for Spine Bone Imaging with Application in Spondylolysis Evaluation

  • Diana Vucevic,
  • Vadim Malis,
  • Yuichi Yamashita,
  • Anya Mesa and ,
  • Tomosuke Yamaguchi,
  • Suraj Achar,
  • Mitsue Miyazaki and
  • Won C. Bae
  • + 3 authors+ 0 author

Isthmic spondylolysis is characterized by a stress injury to the pars interarticularis bones of the lumbar spines and is often missed by conventional magnetic resonance imaging (MRI), necessitating a computed tomography (CT) for accurate diagnosis. W...

(This article belongs to the Special Issue Computational Medical Image Analysis—2nd Edition)
  • Article
  • Open Access

Semiautomatic segmentation of glioblastoma for radiotherapy treatment plannin

  • Giorgio De Nunzio,
  • Benedetta Tafuri,
  • Marina Donativi,
  • Marta Vannini and ,
  • Lorenzo Mazzoni,
  • Giovanni Rubino,
  • Antonella Castellano and
  • Luigi Pirtoli
  • + 3 authors+ 0 author

During the radiation therapy (RT) process, the treatment is planned and simulated with a treatment planning system (TPS). Contouring identifies the Planning Treatment Volume (PTV), that is the physical RT treatment volume. PTV of Glioblastoma (GB) in...

  • Review
  • Open Access
1 Citations
6,768 Views
28 Pages

Pediatric Neuroimaging of Multiple Sclerosis and Neuroinflammatory Diseases

  • Chloe Dunseath,
  • Emma J. Bova,
  • Elizabeth Wilson,
  • Marguerite Care and
  • Kim M. Cecil

20 December 2024

Using a pediatric-focused lens, this review article briefly summarizes the presentation of several demyelinating and neuroinflammatory diseases using conventional magnetic resonance imaging (MRI) sequences, such as T1-weighted with and without an exo...

(This article belongs to the Section Neuroimaging)
  • Article
  • Open Access
5 Citations
5,096 Views
13 Pages

Shoulder Bone Segmentation with DeepLab and U-Net

  • Michael Carl,
  • Kaustubh Lall,
  • Darren Pai,
  • Eric Y. Chang and ,
  • Sheronda Statum,
  • Anja Brau,
  • Christine B. Chung,
  • Maggie Fung and
  • Won C. Bae
  • + 4 authors+ 0 author

11 June 2024

Evaluation of the 3D bone morphology of the glenohumeral joint is necessary for pre-surgical planning. Zero echo time (ZTE) magnetic resonance imaging (MRI) provides excellent bone contrast and can potentially be used in the place of computed tomogra...

  • Review
  • Open Access
41 Citations
15,607 Views
26 Pages

24 January 2024

Deep learning (DL) in magnetic resonance imaging (MRI) shows excellent performance in image reconstruction from undersampled k-space data. Artifact-free and high-quality MRI reconstruction is essential for ensuring accurate diagnosis, supporting clin...

(This article belongs to the Section Sensing and Imaging)
  • Systematic Review
  • Open Access
9 Citations
7,489 Views
20 Pages

The Use of Dixon Magnetic Resonance Imaging Methods for the Quantification of Rotator Cuff Fatty Infiltration: A Systematic Review

  • Andrew J. Nasr,
  • Joshua Harris,
  • Jijia Wang,
  • Michael Khazzam and ,
  • Nitin B. Jain,
  • Yi-Ting Tzen and
  • Yen-Sheng Lin
  • + 2 authors+ 0 author

19 May 2024

Fatty infiltration of the rotator cuff muscles is very common following rotator cuff tears and is one of the most important factors in determining treatment. Current clinical practice relies on subjective evaluation of fatty infiltration through cate...

  • Article
  • Open Access
3 Citations
2,869 Views
38 Pages

2 September 2025

Lately, deep learning methods have greatly improved the accuracy of brain-tumor segmentation, yet slice-wise inconsistencies still limit reliable use in clinical practice. While volume-aware 3D convolutional networks achieve high accuracy, their memo...

  • Article
  • Open Access
6 Citations
6,598 Views
17 Pages

Comprehensive Assessment of Medial Knee Joint Instability by Valgus Stress MRI

  • Malin Ciba,
  • Eva-Maria Winkelmeyer,
  • Justus Schock,
  • Philipp Schad and ,
  • Niklas Kotowski,
  • Teresa Nolte,
  • Lena Marie Wollschläger,
  • Matthias Knobe,
  • Andreas Prescher and
  • Sven Nebelung
  • + 7 authors+ 2 authors

Standard clinical MRI techniques provide morphologic insights into knee joint pathologies, yet do not allow evaluation of ligament functionality or joint instability. We aimed to study valgus stress MRI, combined with sophisticated image post-process...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Feature Paper
  • Article
  • Open Access
7 Citations
3,949 Views
11 Pages

31 October 2022

The aim of this study was to explore whether intravoxel incoherent motion (IVIM) combined with a dynamic contrast–enhanced magnetic resonance imaging (DCE–MRI) quantitative model can improve the ability to distinguish between benign and m...

(This article belongs to the Special Issue Quantitative Imaging in Oncology)
  • Article
  • Open Access
17 Citations
7,431 Views
12 Pages

Quantitative Synthetic Magnetic Resonance Imaging for Brain Metastases: A Feasibility Study

  • Amaresha Shridhar Konar,
  • Akash Deelip Shah,
  • Ramesh Paudyal,
  • Maggie Fung and ,
  • Suchandrima Banerjee,
  • Abhay Dave,
  • Vaios Hatzoglou and
  • Amita Shukla-Dave
  • + 3 authors+ 0 author

27 May 2022

The present preliminary study aims to characterize brain metastases (BM) using T1 and T2 maps generated from newer, rapid, synthetic MRI (MAGnetic resonance image Compilation; MAGiC) in a clinical setting. We acquired synthetic MRI data from 11 BM pa...

(This article belongs to the Special Issue Characterization of Tumor Physiology Using Magnetic Resonance Imaging (MRI))
  • Article
  • Open Access
12 Citations
8,644 Views
17 Pages

Radio Frequency Modeling of Receive Coil Arrays for Magnetic Resonance Imaging

  • Christopher Stumpf,
  • Matthias Malzacher and
  • Lorenz-Peter Schmidt

The numerical calculation of the signal-to-noise ratio (SNR) of magnetic resonance imaging (MRI) coil arrays is a powerful tool in the development of new coil arrays. The proposed method describes a complete model that allows the calculation of the a...

  • Article
  • Open Access
199 Citations
18,240 Views
30 Pages

A Survey of Brain Tumor Segmentation and Classification Algorithms

  • Erena Siyoum Biratu,
  • Friedhelm Schwenker,
  • Yehualashet Megersa Ayano and
  • Taye Girma Debelee

6 September 2021

A brain Magnetic resonance imaging (MRI) scan of a single individual consists of several slices across the 3D anatomical view. Therefore, manual segmentation of brain tumors from magnetic resonance (MR) images is a challenging and time-consuming task...

(This article belongs to the Special Issue Advanced Computational Methods for Oncological Image Analysis)
  • Systematic Review
  • Open Access
5 Citations
3,488 Views
23 Pages

The Value of Cerebral Blood Volume Derived from Dynamic Susceptibility Contrast Perfusion MRI in Predicting IDH Mutation Status of Brain Gliomas—A Systematic Review and Meta-Analysis

  • José Pablo Martínez Barbero,
  • Francisco Javier Pérez García,
  • Paula María Jiménez Gutiérrez,
  • Marta García Cerezo and ,
  • David López Cornejo,
  • Gonzalo Olivares Granados,
  • José Manuel Benítez and
  • Antonio Jesús Láinez Ramos-Bossini
  • + 3 authors+ 0 author

Background: Dynamic susceptibility contrast perfusion MRI (DSC-MRI) is a promising non-invasive examination to predict histological and molecular characteristics of brain gliomas. However, the diagnostic accuracy of relative cerebral blood volume (rC...

(This article belongs to the Special Issue New Advances in Neurosurgery: Clinical Diagnosis, Treatment and Prognosis)
  • Review
  • Open Access
8 Citations
3,134 Views
19 Pages

5 December 2025

Drug-resistant epilepsy affects nearly one-third of individuals with epilepsy and remains a major cause of neurological morbidity worldwide. Surgical intervention offers a potential cure, but its success critically depends on the precise identificati...

(This article belongs to the Section Personalized Therapy in Clinical Medicine)
  • Article
  • Open Access
31 Citations
2,067 Views
9 Pages

A Population-Based Digital Reference Object (DRO) for Optimizing Dynamic Susceptibility Contrast (DSC)-MRI Methods for Clinical Trials

  • Natenael B. Semmineh,
  • Ashley M. Stokes,
  • Laura C. Bell,
  • Jerrold L. Boxerman and
  • C. Chad Quarles

1 August 2017

The standardization and broad-scale integration of dynamic susceptibility contrast (DSC)-magnetic resonance imaging (MRI) have been confounded by a lack of consensus on DSC-MRI methodology for preventing potential relative cerebral blood volume inacc...

  • Article
  • Open Access
2 Citations
1,947 Views
11 Pages

Cardiac Magnetic Resonance Imaging with Myocardial Strain Assessment Correlates with Cardiopulmonary Exercise Testing in Patients with Pectus Excavatum

  • André Lollert,
  • Tariq Abu-Tair,
  • Tilman Emrich,
  • Karl-Friedrich Kreitner and ,
  • Alexander Sterlin,
  • Christoph Kampmann and
  • Gundula Staatz
  • + 2 authors+ 0 author

7 December 2024

Objectives: To evaluate correlations between cardiac magnetic resonance imaging (cMRI) at rest including strain imaging and variables derived from quantitative cardiopulmonary exercise testing using a treadmill in patients with pectus excavatum. Meth...

(This article belongs to the Special Issue Diagnosis of Valvular Heart Disease and Myocardial Function)
  • Review
  • Open Access
6 Citations
5,774 Views
14 Pages

3D Printing—A Cutting Edge Technology for Treating Post-Infarction Patients

  • Daniel Cernica,
  • Imre Benedek,
  • Stefania Polexa,
  • Cosmin Tolescu and
  • Theodora Benedek

1 September 2021

The increasing complexity of cardiovascular interventions requires advanced peri-procedural imaging and tailored treatment. Three-dimensional printing technology represents one of the most significant advances in the field of cardiac imaging, interve...

(This article belongs to the Section Medical Research)
  • Article
  • Open Access
5 Citations
2,610 Views
11 Pages

Predicting the Early Response to Neoadjuvant Therapy with Breast MR Morphological, Functional and Relaxometry Features—A Pilot Study

  • Roxana Pintican,
  • Radu Fechete,
  • Bianca Boca,
  • Madalina Cambrea and ,
  • Tiberiu Leonte,
  • Oana Camuescu,
  • Diana Gherman,
  • Ioana Bene,
  • Larisa Dorina Ciule and
  • Anca Ileana Ciurea
  • + 7 authors+ 2 authors

28 November 2022

Aim: To evaluate the role of MR relaxometry and derived proton density analysis in the prediction of early treatment response after two cycles of neoadjuvant therapy (NAT), in patients with breast cancer. Methods: This was a prospective study that in...

(This article belongs to the Collection The Molecular Predictive and Prognostic Biomarkers in Breast Cancer)
  • Article
  • Open Access
30 Citations
6,384 Views
22 Pages

Computational Detection of Extraprostatic Extension of Prostate Cancer on Multiparametric MRI Using Deep Learning

  • Ştefania L. Moroianu,
  • Indrani Bhattacharya,
  • Arun Seetharaman,
  • Wei Shao and ,
  • Christian A. Kunder,
  • Avishkar Sharma,
  • Pejman Ghanouni,
  • Richard E. Fan,
  • Geoffrey A. Sonn and
  • Mirabela Rusu
  • + 5 authors+ 0 author

7 June 2022

The localization of extraprostatic extension (EPE), i.e., local spread of prostate cancer beyond the prostate capsular boundary, is important for risk stratification and surgical planning. However, the sensitivity of EPE detection by radiologists on...

(This article belongs to the Special Issue Non-invasive Methods for Screening, Prognosis, and Prediction in Prostate Cancers)
  • Communication
  • Open Access
3 Citations
3,088 Views
12 Pages

High-Resolution Magnetic Resonance Neurography at 7T: A Pilot Study of Hand Innervation

  • Pauline C. Guillemin,
  • David Ferreira Branco,
  • Yacine M’Rad,
  • Loan Mattera and ,
  • Orane Lorton,
  • Gian Franco Piredda,
  • Antoine Klauser,
  • Roberto Martuzzi,
  • Pierre-Alexandre Poletti and
  • Sana Boudabbous
  • + 6 authors+ 1 author

The emergence of 7T clinical MRI technology has sparked our interest in its ability to discern the complex structures of the hand. Our primary objective was to assess the sensory and motor nerve structures of the hand, specifically nerves and Pacinia...

(This article belongs to the Special Issue Clinical Advances and Applications in Neuroradiology)
  • Systematic Review
  • Open Access
8 Citations
5,553 Views
15 Pages

The Role of CT Perfusion in the Evaluation and Management of Acute Ischemic Stroke—A Systematic Review

  • Rares C. Bobe,
  • Roxana E. Coroiu,
  • Adelina E. Cirstian,
  • Camelia I. Cristescu and ,
  • Diana A. Pepelea and
  • Rosana M. Manea
  • + 1 author+ 0 author

31 October 2025

Background: CT perfusion (CTP) is increasingly used in the evaluation of acute ischemic stroke (AIS) and may complement non-contrast CT (NCCT) and CT angiography (CTA). This review aimed to assess the role of CTP in patient selection for reperfusion...

(This article belongs to the Special Issue Advances in Endovascular Therapies and Acute Stroke Management)
  • Review
  • Open Access
5 Citations
3,156 Views
40 Pages

15 November 2025

Chemical Exchange Saturation Transfer (CEST) imaging has emerged as a promising non-invasive molecular MRI technique for investigating neuroinflammation. It offers unique insights into metabolic and molecular alterations in the brain. This review pre...

(This article belongs to the Section Molecular Neurobiology)
  • Article
  • Open Access
2 Citations
1,832 Views
11 Pages

Improved Visualization and Quantification of Net Water Uptake in Recent Small Subcortical Infarcts in the Thalamus Using Computed Tomography

  • Felix Schön,
  • Hannes Wahl,
  • Arne Grey,
  • Pawel Krukowski and ,
  • Angela Müller,
  • Volker Puetz,
  • Jennifer Linn and
  • Daniel P. O. Kaiser
  • + 3 authors+ 0 author

9 November 2023

Diagnosing recent small subcortical infarcts (RSSIs) via early computed tomography (CT) remains challenging. This study aimed to assess CT attenuation values (Hounsfield Units (HU)) and net water uptake (NWU) in RSSI and explore a postprocessing algo...

(This article belongs to the Special Issue Cerebrovascular Lesions: Diagnosis and Management)
  • Article
  • Open Access
1 Citations
2,826 Views
7 Pages

Variation in Diffusion Tensor Imaging Parameters in the Cervical and Thoracic Spinal Cord (C1-C5 and C6-T2) Segments of Normal Beagle Dogs

  • Kiyotaka Arai,
  • Takamasa Itoi,
  • Natsuki Akashi,
  • Masahiro Miyabe and ,
  • Keisuke Sugimoto,
  • Akira Matsuda,
  • Noritaka Maeta,
  • Teppei Kanda and
  • Kenji Kutara
  • + 4 authors+ 0 author

1 January 2023

This study aimed to determine the characteristics and reference values of each vertebra in the cervicothoracic region by performing diffusion tensor imaging (DTI) scans and analyzing DTI parameters in normal Beagle dogs. In five adult Beagles under a...

  • Article
  • Open Access
3 Citations
3,947 Views
16 Pages

Development and Validation of Four Different Methods to Improve MRI-CEST Tumor pH Mapping in Presence of Fat

  • Francesco Gammaraccio,
  • Daisy Villano,
  • Pietro Irrera,
  • Annasofia A. Anemone and ,
  • Antonella Carella,
  • Alessia Corrado and
  • Dario Livio Longo
  • + 2 authors+ 0 author

CEST-MRI is an emerging imaging technique suitable for various in vivo applications, including the quantification of tumor acidosis. Traditionally, CEST contrast is calculated by asymmetry analysis, but the presence of fat signals leads to wrong cont...

(This article belongs to the Section Medical Imaging)
  • Review
  • Open Access
102 Citations
6,994 Views
11 Pages

Deep Learning Applications in Magnetic Resonance Imaging: Has the Future Become Present?

  • Sebastian Gassenmaier,
  • Thomas Küstner,
  • Dominik Nickel,
  • Judith Herrmann and ,
  • Rüdiger Hoffmann,
  • Haidara Almansour,
  • Saif Afat,
  • Konstantin Nikolaou and
  • Ahmed E. Othman
  • + 4 authors+ 0 author

24 November 2021

Deep learning technologies and applications demonstrate one of the most important upcoming developments in radiology. The impact and influence of these technologies on image acquisition and reporting might change daily clinical practice. The aim of t...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
4 Citations
7,578 Views
22 Pages

Conformal-Based Surface Morphing and Multi-Scale Representation

  • Ka Chun Lam,
  • Chengfeng Wen and
  • Lok Ming Lui

20 May 2014

This paper presents two algorithms, based on conformal geometry, for the multi-scale representations of geometric shapes and surface morphing. A multi-scale surface representation aims to describe a 3D shape at different levels of geometric detail, w...

(This article belongs to the Special Issue Discrete Differential Geometry and Its Applications to Imaging and Graphics)
  • Article
  • Open Access
2 Citations
2,926 Views
14 Pages

Assessment of Intervertebral Lumbar Disk Herniation: Accuracy of Dual-Energy CT Compared to MRI

  • Giuseppe Ocello,
  • Gianluca Tripodi,
  • Flavio Spoto,
  • Leonardo Monterubbiano and ,
  • Gerardo Serra,
  • Giorgio Merci and
  • Giovanni Foti
  • + 2 authors+ 0 author

3 October 2025

Background: Lumbar disk herniation is a common cause of low back pain and radiculopathy, significantly impacting patients’ life quality and functional capacity. Magnetic Resonance Imaging (MRI) remains the gold standard for its assessment due t...

(This article belongs to the Section Nuclear Medicine & Radiology)

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