Skip to Content
You are currently on the new version of our website. Access the old version .

61 Results Found

  • Article
  • Open Access
189 Views
16 Pages

15 October 2026

This study comparatively evaluated the chemical fingerprints and oleuropein contents of commercially available olive leaf extracts on the Turkish dietary supplement market. Six independent commercial products, comprising three liquid and three powder...

(This article belongs to the Section Nutraceuticals, Functional Foods, and Novel Foods)
  • Article
  • Open Access
12 Citations
8,531 Views
19 Pages

Characterization of Flavonoids in the Ethomedicine Fordiae Cauliflorae Radix and Its Adulterant Millettiae Pulchrae Radix by HPLC-DAD-ESI-IT-TOF-MSn

  • Lan-Lan Fan,
  • Tao Yi,
  • Feng Xu,
  • Ya-Zhou Zhang and ,
  • Jian-Ye Zhang,
  • Dian-Peng Li,
  • Yang-Jiao Xie,
  • Shan-Ding Qin and
  • Hu-Biao Chen
  • + 4 authors+ 0 author

9 December 2013

Fordiae Cauliflorae Radix (FC, the root of Fordia cauliflora Hemsl) and Millettiae Pulchrae Radix [MP, the root of Millettia pulchra (Benth.) Kurz var. laxior (Dunn) Z. Wei], which go under the same local name of “Daluosan”, have long been used in So...

  • Article
  • Open Access
22 Citations
9,766 Views
24 Pages

Chemical Profile Analysis and Comparison of Two Versions of the Classic TCM Formula Danggui Buxue Tang by HPLC-DAD-ESI-IT-TOF-MSn

  • Ya-Zhou Zhang,
  • Feng Xu,
  • Tao Yi,
  • Jian-Ye Zhang and ,
  • Jun Xu,
  • Yi-Na Tang,
  • Xi-Chen He,
  • Jing Liu and
  • Hu-Biao Chen
  • + 4 authors+ 0 author

30 April 2014

Danggui Buxue Tang (DBT) is a Traditional Chinese Medicine (TCM) formula primarily used to treat symptoms associated with menopause in women. Usually, DBT is composed of one portion of Radix Angelicae Sinensis (RAS) and five portions of Radix Astraga...

(This article belongs to the Section Metabolites)
  • Article
  • Open Access
43 Citations
7,888 Views
19 Pages

15 February 2022

Helichrysum arenarium (L.) Moench (sandy everlasting) is the only species from genus Helichrysum Mill that grows spontaneously in Lithuania. The chemical composition of the essential oils (EOs) from inflorescences and leaves of H. arenarium wild plan...

(This article belongs to the Special Issue Chemical Composition and Biological Activity of Essential Oils and Other Extracts: From Extraction to Application)
  • Article
  • Open Access
19 Citations
7,441 Views
20 Pages

23 March 2023

Native to N. America, Canadian goldenrod (Solidago canadensis L.) was introduced to Europe as an ornamental plant and quickly spread here and in other parts of the world. The rapid spread of the plant is due to several reasons: phenotypic plasticity,...

(This article belongs to the Special Issue Structural and Functional Analysis of Extracts in Plants III)
  • Article
  • Open Access
3 Citations
2,107 Views
21 Pages

23 January 2026

Heracleum sosnowskyi is considered to be a dangerous invasive plant species that has successfully naturalized within a variety of plant communities across numerous countries. As a result of its superior competitiveness, the alien species is able to d...

(This article belongs to the Special Issue Extraction, Isolation and Characterization of Bioactive Compounds from Plants)
  • Article
  • Open Access
1 Citations
1,247 Views
20 Pages

Nowadays, the global demand for medicinal plants, including A. absinthium L. (wormwood), has increased considerably, leading to significant pressure on their wild populations and the biodiversity of ecosystems. Consequently, the rates of exploitation...

(This article belongs to the Special Issue Chemical Composition and Biological Activity of Essential Oils and Other Extracts: From Extraction to Application, Second Edition)
  • Article
  • Open Access
277 Views
19 Pages

18 September 2026

Erigeron sp. has been employed for medicinal purposes in the ethnopharmacology of numerous countries worldwide, as well as in modern-day herbal applications. Their healing capacity is determined by their bioactive compound content, with polyphenols p...

(This article belongs to the Special Issue Bioactive Natural Products from Plants: Extraction, Characterization and Application)
  • Article
  • Open Access
37 Citations
4,976 Views
17 Pages

11 April 2019

Background: Qianhu is a traditional Chinese medicine. It is thought that Qianhu roots will harden after bolting and not be suitable for medicinal purposes. Bolting Qianhu and unbolting Qianhu are referred to as “Xiong Qianhu” and “C...

  • Article
  • Open Access
3 Citations
3,163 Views
16 Pages

Evaluation of Chokeberry/Carboxymethylcellulose Hydrogels with the Addition of Disaccharides: DART-TOF/MS and HPLC-DAD Analysis

  • Ina Ćorković,
  • Aleš Rajchl,
  • Tereza Škorpilová,
  • Anita Pichler and ,
  • Josip Šimunović and
  • Mirela Kopjar
  • + 1 author+ 0 author

27 December 2022

With the growing awareness of the importance of a healthy diet, the need for the development of novel formulations is also on the rise. Chokeberry products are popular among consumers since they are a rich source of polyphenols that are responsible f...

(This article belongs to the Section Macromolecules)
  • Article
  • Open Access
15 Citations
4,975 Views
16 Pages

Analysis of Intact Glycosidic Aroma Precursors in Grapes by High-Performance Liquid Chromatography with a Diode Array Detector

  • Cristina Cebrián-Tarancón,
  • José Oliva,
  • Miguel Ángel Cámara,
  • Gonzalo L. Alonso and
  • M. Rosario Salinas

19 January 2021

Nowadays, the techniques for the analysis of glycosidic precursors in grapes involve changes in the glycoside structure or it is necessary the use of very expensive analytical techniques. In this study, we describe for the first time an approach to a...

(This article belongs to the Special Issue Recent Developments in Identification of Genuine Odor- and Taste-Active Compounds in Foods)
  • Article
  • Open Access
14 Citations
4,557 Views
12 Pages

HPLC-DAD-qTOF Compositional Analysis of the Phenolic Compounds Present in Crude Tomato Protein Extracts Derived from Food Processing

  • Ana Miklavčič Višnjevec,
  • Paul W. Baker,
  • Kelly Peeters,
  • Matthew Schwarzkopf and ,
  • Dominik Krienke and
  • Adam Charlton
  • + 1 author+ 0 author

23 October 2021

The conversion of raw fruits and vegetables, including tomatoes into processed food products creates side streams of residues that can place a burden on the environment. However, these processed residues are still rich in bioactive compounds and in a...

(This article belongs to the Special Issue Antioxidants from Natural Sources: Separation and Characterization)
  • Article
  • Open Access
17 Citations
3,669 Views
22 Pages

Exploring the In Vivo Existence Forms (23 Original Constituents and 147 Metabolites) of Astragali Radix Total Flavonoids and Their Distributions in Rats Using HPLC-DAD-ESI-IT-TOF-MSn

  • Li-Jia Liu,
  • Hong-Fu Li,
  • Feng Xu,
  • Hong-Yan Wang and ,
  • Yi-Fan Zhang,
  • Guang-Xue Liu,
  • Ming-Ying Shang,
  • Xuan Wang and
  • Shao-Qing Cai
  • + 4 authors+ 0 author

26 November 2020

Astragali Radix total flavonoids (ARTF) is one of the main bioactive components of Astragali Radix (AR), and has many pharmacological effects. However, its metabolism and effective forms remains unclear. The HPLC-DAD-ESI-IT-TOF-MSn technique was used...

  • Article
  • Open Access
19 Citations
5,300 Views
19 Pages

In Vitro Antioxidant and Prooxidant Activities of Red Raspberry (Rubus idaeus L.) Stem Extracts

  • Rasa Garjonyte,
  • Jurga Budiene,
  • Linas Labanauskas and
  • Asta Judzentiene

24 June 2022

Leaves and stems of red raspberry (Rubus idaeus) are used in Lithuanian folk medicine. Healing properties of raspberry are related to the content of bioactive compounds, mainly polyphenols. Extracts of raspberry leaves contained higher total phenolic...

(This article belongs to the Special Issue Chemical Composition and Biological Activity of Essential Oils and Other Extracts: From Extraction to Application)
  • Article
  • Open Access
6 Citations
4,466 Views
16 Pages

Tanacetum vulgare is a perennial plant growing wild along roadsides, pastures, and agricultural fields. Its prevalence is due to several factors: good climatic adaptability, high self-seeding potential, phenotypic plasticity, multiplying via undergro...

  • Article
  • Open Access
13 Citations
3,610 Views
19 Pages

6 November 2023

Astragalus membranaceus is a traditional Chinese medicine derived from the roots of Astragalus membranaceus (Fisch.) Bge., which has the same medicinal and edible uses in China. It is also widely used in daily food, and its pharmacological effects ma...

(This article belongs to the Section Natural Products Chemistry)
  • Article
  • Open Access
61 Citations
9,421 Views
14 Pages

18 January 2020

Onion is widely used worldwide in various forms for both food and medicinal applications, thanks to its high content of phytonutrients, such as flavonoids and volatile sulfur compounds. Fresh onion is very perishable and drying is widely applied for...

(This article belongs to the Special Issue Analysis of Volatile and Odor Compounds in Food)
  • Article
  • Open Access
19 Citations
2,662 Views
27 Pages

Optimization of Conventional and Ultrasound-Assisted Extraction to Maximize Recovery of Total Phenolic Content and In Vitro Antioxidant Activity from Crataegus almaatensis Leaves

  • Zhanar Nabiyeva,
  • Akerke Kulaipbekova,
  • Serena Carpentieri,
  • Yuliya Pronina and ,
  • Abdyssemat Samadun,
  • Elmira Assembayeva and
  • Giovanna Ferrari
  • + 2 authors+ 0 author

16 August 2025

Background: Crataegus almaatensis, an endemic hawthorn species from Kazakhstan, is known for its rich content of phenolic compounds and flavonoids with significant pharmacological potential. This study aimed to optimize and compare conventional solid...

(This article belongs to the Special Issue Antioxidants from Food and Food Wastes for Nutraceutical, Pharmaceutical and Cosmetic Fields)
  • Article
  • Open Access
21 Citations
5,095 Views
14 Pages

Developing an Olive Biorefinery in Slovenia: Analysis of Phenolic Compounds Found in Olive Mill Pomace and Wastewater

  • Ana Miklavčič Višnjevec,
  • Paul Baker,
  • Adam Charlton,
  • Dave Preskett and ,
  • Kelly Peeters,
  • Črtomir Tavzes,
  • Katja Kramberger and
  • Matthew Schwarzkopf
  • + 3 authors+ 0 author

22 December 2020

The valorization of olive pomace through the extraction of phenolic compounds at an industrial scale is influenced by several factors that can have a significant impact on the feasibility of this approach. These include the types and levels of phenol...

(This article belongs to the Special Issue Plant Natural Products: Isolation, Identification and Biological Activity)
  • Article
  • Open Access
28 Citations
5,344 Views
14 Pages

Glucosinolates and Isothiocyantes in Processed Rapeseed Determined by HPLC-DAD-qTOF

  • Ana Miklavčič Višnjevec,
  • Angelica Tamayo Tenorio,
  • Anne Christine Steenkjær Hastrup,
  • Natanya Majbritt Louie Hansen and ,
  • Kelly Peeters and
  • Matthew Schwarzkopf
  • + 1 author+ 0 author

22 November 2021

Glucosinolates are well known as natural antimicrobials and anticarcinogenic agents. However, these compounds can lose their properties and transform into antinutrients, depending on processing conditions. In addition, the bitterness of some glucosin...

(This article belongs to the Special Issue Chemical Profiling and Biological Activity of Plant Natural Compounds)
  • Article
  • Open Access
24 Citations
5,196 Views
19 Pages

Phytochemical Characterization and Bioactivity of Asparagus acutifolius: A Focus on Antioxidant, Cytotoxic, Lipase Inhibitory and Antimicrobial Activities

  • Amel Hamdi,
  • Sara Jaramillo-Carmona,
  • Rocío Rodríguez-Arcos,
  • Ana Jiménez-Araujo and ,
  • Mokhtar Lachaal,
  • Najoua Karray-Bouraoui and
  • Rafael Guillén-Bejarano
  • + 2 authors+ 0 author

The phytochemical composition of leaves, stems, pericarps and rhizomes ethanolic extracts of Asparagus acutifolius were characterized by HPLC-DAD-MS. A. acutifolius samples contain at least eleven simple phenolics, one flavonon, two flavonols and six...

(This article belongs to the Section Natural Products Chemistry)
  • Article
  • Open Access
7 Citations
3,803 Views
22 Pages

Phytochemical Profile and In Vitro Bioactivities of Wild Asparagus stipularis

  • Amel Hamdi,
  • Sara Jaramillo-Carmona,
  • Rocío Rodríguez-Arcos,
  • Ana Jiménez-Araujo and ,
  • Najoua Karray Bouraoui and
  • Rafael Guillén-Bejarano
  • + 1 author+ 0 author

10 February 2024

In this study, Asparagus stipularis was characterized concerning its phytochemical composition, antioxidant potential, cytotoxicity, and pancreatic lipase inhibitory activities. Twenty-seven compounds were identified and quantified by HPLC-DAD-MS in...

(This article belongs to the Special Issue Naturally Inspired Molecules as Inhibitors in Drug Discovery)
  • Article
  • Open Access
64 Citations
6,845 Views
11 Pages

Antiplatelet Activity of Natural Bioactive Extracts from Mango (Mangifera Indica L.) and its By-Products

  • María Elena Alañón,
  • Iván Palomo,
  • Lyanne Rodríguez,
  • Eduardo Fuentes and ,
  • David Arráez-Román and
  • Antonio Segura-Carretero
  • + 1 author+ 0 author

29 October 2019

The potential antiplatelet aggregation effects of mango pulp and its by-products (peel, husk seed, and seed) due to the presence of bioactive compounds were explored. Among them, mango seed exhibited a 72% percentage inhibition of platelet aggregatio...

(This article belongs to the Special Issue Polyphenolic Antioxidants from Agri-Food Waste Biomass)
  • Article
  • Open Access
114 Citations
7,580 Views
17 Pages

Obtaining an Extract Rich in Phenolic Compounds from Olive Pomace by Pressurized Liquid Extraction

  • Inés Cea Pavez,
  • Jesús Lozano-Sánchez,
  • Isabel Borrás-Linares,
  • Hugo Nuñez and ,
  • Paz Robert and
  • Antonio Segura-Carretero
  • + 1 author+ 0 author

27 August 2019

The olive oil industry produces large volumes of wastes, which are also potential sources of bioactive compounds by developing healthy and/or functional foods. Extraction of phenolic compounds from the residues of the olive oil is mainly carried out...

(This article belongs to the Special Issue Bioactives from Bioprocessing: Sources and Production)
  • Article
  • Open Access
58 Citations
4,565 Views
14 Pages

Antioxidant Activity and Polyphenols Characterization of Four Monovarietal Grape Pomaces from Salento (Apulia, Italy)

  • Carmine Negro,
  • Alessio Aprile,
  • Andrea Luvisi,
  • Luigi De Bellis and
  • Antonio Miceli

1 September 2021

The wine industry annually produces millions of tons of by-products rich in polyphenolic compounds that can be reused as secondary raw material in the food, cosmetic and pharmaceutical industries. The purpose of this work was to describe the presence...

  • Article
  • Open Access
39 Citations
6,963 Views
21 Pages

22 June 2023

The phytochemistry of fibre hemp (Cannabis sativa L., cv. Futura 75 and Felina 32) cultivated in Lithuania was investigated. The soil characteristics (conductivity, pH and major elements) of the cultivation field were determined. The chemical composi...

(This article belongs to the Special Issue Advances in Natural Products and Their Biological Activities)
  • Article
  • Open Access
21 Citations
6,611 Views
11 Pages

Mori Ramulus (Chin.Ph.)—the Dried Twigs of Morus alba L./Part 1: Discovery of Two Novel Coumarin Glycosides from the Anti-Hyperuricemic Ethanol Extract

  • Jianbiao Yao,
  • Houhong He,
  • Jin Xue,
  • Jianfang Wang and ,
  • Huihui Jin,
  • Jian Wu,
  • Jiangning Hu,
  • Ruwei Wang and
  • Kenny Kuchta
  • + 4 authors+ 0 author

11 February 2019

In Traditional Chinese Medicine (TCM), Mori ramulus (Chin.Ph.)—the dried twigs of Morus alba L.—is extensively used as an antirheumatic agent and also finds additional use in asthma therapy. As a pathological high xanthine oxidase (XO, EC...

(This article belongs to the Collection Herbal Medicine Research)
  • Article
  • Open Access
44 Citations
5,682 Views
17 Pages

Complementary Untargeted and Targeted Metabolomics for Differentiation of Extra Virgin Olive Oils of Different Origin of Purchase Based on Volatile and Phenolic Composition and Sensory Quality

  • Alessio Da Ros,
  • Domenico Masuero,
  • Samantha Riccadonna,
  • Karolina Brkić Bubola and ,
  • Nadia Mulinacci,
  • Fulvio Mattivi,
  • Igor Lukić and
  • Urska Vrhovsek
  • + 3 authors+ 0 author

9 August 2019

In order to differentiate the extra virgin olive oils (EVOO) of different origin of purchase, such as monovarietal Italian EVOO with protected denomination of origin (PDO) and commercial-blended EVOO purchased in supermarkets, a number of samples was...

(This article belongs to the Special Issue Olive Bioactives: From Molecules to Human Health)
  • Article
  • Open Access
59 Citations
8,899 Views
24 Pages

31 July 2015

Alismatis Rhizoma (AMR) is a well-known natural medicine with a long history in Chinese medicine and has been commonly used for treating a wide range of ailments related to dysuria, edema, nephropathy, hyperlipidaemia, diabetes, inflammation as well...

(This article belongs to the Section Natural Products Chemistry)
  • Article
  • Open Access
10 Citations
1,796 Views
22 Pages

Chemical Composition and In Vitro Biological Activity of the Polar and Non-Polar Fractions Obtained from the Roots of Eleutherococcus senticosus (Rupr. et Maxim.) Maxim

  • Jakub Gębalski,
  • Milena Małkowska,
  • Ewa Kiełkowska,
  • Filip Graczyk and ,
  • Sylwia Wnorowska,
  • Iga Hołyńska-Iwan,
  • Maciej Strzemski,
  • Magdalena Wójciak and
  • Daniel Załuski
  • + 4 authors+ 0 author

Eleutherococcus senticosus (ES) has been used in traditional medicine for immune-boosting, stress-reducing, and endurance-enhancing properties. In this study, the chemical composition and biological activity of polar and non-polar fractions obtained...

(This article belongs to the Section Molecular Pharmacology)
  • Article
  • Open Access
60 Citations
12,581 Views
14 Pages

Recovering Bioactive Compounds from Olive Oil Filter Cake by Advanced Extraction Techniques

  • Jesús Lozano-Sánchez,
  • María Castro-Puyana,
  • Jose A. Mendiola,
  • Antonio Segura-Carretero and ,
  • Alejandro Cifuentes and
  • Elena Ibáez
  • + 1 author+ 0 author

15 September 2014

The potential of by-products generated during extra-virgin olive oil (EVOO) filtration as a natural source of phenolic compounds (with demonstrated bioactivity) has been evaluated using pressurized liquid extraction (PLE) and considering mixtures of...

(This article belongs to the Special Issue Bioactive Phenolics and Polyphenols)
  • Article
  • Open Access
4 Citations
2,906 Views
14 Pages

Validation of an Analytical Method of 3′,4′,5-Trihydroxy-3-Methoxy-6,7-Methylenedioxyflavone 4′-Glucuronide for Standardization of Spinacia oleracea

  • Yun Gon Son,
  • Juyoung Jung,
  • Dong Kun Lee,
  • Sang Won Park and ,
  • Jeong Yoon Kim and
  • Hyun Joon Kim
  • + 1 author+ 0 author

Spinach (Spinacia oleracea) is one of the most famous vegetables worldwide, rich in essential metabolites for various health benefits. It is a valuable plant source that has the potential to be a nutraceutical. This study aimed to evaluate the single...

(This article belongs to the Special Issue Chromatographic Methods for Monitoring Food Safety and Quality)
  • Article
  • Open Access
23 Citations
6,791 Views
14 Pages

Rapid Characterization of Triterpene Saponins from Zornia brasiliensis by HPLC-ESI-MS/MS

  • Yuri Mangueira Nascimento,
  • Lucas Silva Abreu,
  • Ramon Leal Lima,
  • Vicente Carlos O. Costa and ,
  • José Iranildo Miranda de Melo,
  • Raimundo Braz-Filho,
  • Marcelo Sobral Silva and
  • Josean Fechine Tavares
  • + 3 authors+ 0 author

10 July 2019

Zornia brasiliensis Vogel (Leguminosae) is a species popularly known in Brazil as “urinária”, “urinana”, and “carrapicho”, it is popularly used as a diuretic and in the treatment of venereal diseases. A spec...

(This article belongs to the Special Issue Saponins)
  • Article
  • Open Access
60 Citations
9,516 Views
25 Pages

5 March 2015

Radix Astragali (RA) is one of the commonly-used traditional Chinese medicines (TCMs) with an immunomodulatory effect confirmed in the clinic. In order to better understand the material basis for the therapeutic effects, this study was to investigate...

(This article belongs to the Special Issue Bioactive Phytochemicals and Functional Food Ingredients in Fruits and Vegetables)
  • Article
  • Open Access
6 Citations
3,580 Views
15 Pages

24 February 2024

FLH 13-11 is an F1 interspecific hybrid muscadine grape genotype that was developed to produce new anthocyanins for pigment color stability. This hybrid resulted from a cross between ‘Marsh’ (Vitis munsoniana) and ‘Magoon’ (V....

(This article belongs to the Section Plant-Crop Biology and Biochemistry)
  • Article
  • Open Access
1 Citations
1,795 Views
23 Pages

Berries from Luzuriaga radicans Ruiz & Pav.: A Southern Chile Climbing Shrub as a Source of Antioxidants Against Chronic Diseases

  • Sebastian Scharf,
  • Javier Romero-Parra,
  • Peter Winterhalter,
  • Alfredo Torres-Benítez and ,
  • Recep Gök and
  • Mario J. Simirgiotis
  • + 1 author+ 0 author

17 August 2025

In recent years, numerous studies have emerged on the biological activities of endemic berries from the Valdivian Forest and their potential for therapeutic use. However, some species appear to have been relatively neglected. The objective of this st...

(This article belongs to the Section Phytochemistry)
  • Article
  • Open Access
20 Citations
7,192 Views
14 Pages

As a traditional Chinese medicinal herb, ginseng (Panax ginseng C. A. Mey.) is commonly used to treat common diseases, for example, esophageal cancer and myasthenia gravis. Furthermore, ginseng is also processed into a functional food additive that i...

(This article belongs to the Topic Application of Liquid Chromatography-Mass Spectrometry and Related Techniques)
  • Article
  • Open Access
10 Citations
4,219 Views
30 Pages

19 August 2022

Strawberry leaves are considered a valuable waste material; so far, mainly due to their antioxidant properties. Since the annual production of this crop is high, our study aimed to thoroughly examine the chemical composition and antidiabetes-related...

(This article belongs to the Special Issue Phytochemistry and Biological Properties of Medicinal Plants)
  • Article
  • Open Access
4 Citations
2,570 Views
24 Pages

Antibacterial, Antifungal, and Wound-Healing Activities and Chemical Characterization of Propolis from Apis mellifera in Michoacan, Mexico

  • Ana Bertha Hernandez-Hernandez,
  • Mario Rodriguez-Canales,
  • Pilar Dominguez-Verano,
  • Uriel Nava-Solis and ,
  • Marco Aurelio Rodriguez-Monroy and
  • María Margarita Canales-Martinez
  • + 1 author+ 0 author

25 September 2025

The aim of this study was to evaluate the antibacterial and antifungal activities, wound-healing efficacy, and chemical characteristics of hexanic, chloroformic, and methanolic extracts of propolis from Michoacan, Mexico. Antibacterial activity was d...

(This article belongs to the Special Issue Bee Products: Recent Progress in Health Benefits Studies, 2nd Edition)
  • Article
  • Open Access
8 Citations
3,304 Views
11 Pages

Identification of Bioactive Compounds of Asparagus officinalis L.: Permutation Test Allows Differentiation among “Triguero” and Hybrid Green Varieties

  • Cecilia Jiménez-Sánchez,
  • Fabián Pedregosa,
  • Isabel Borrás-Linares,
  • Jesús Lozano-Sánchez and
  • Antonio Segura-Carretero

15 March 2021

In this study, we determined the phytochemical profile of the Spanish “triguero” asparagus landrace “verde-morado” (Asparagus officinalis L.), a wild traditional landrace, and the improved “triguero” HT-801, together with two commercial green asparag...

(This article belongs to the Section Natural Products Chemistry)
  • Article
  • Open Access
549 Views
12 Pages

Time-Dependent Degradation of Imipenem in Aqueous Solution and Its Impact on Antibacterial Activity

  • Gu Hae Kim,
  • Na Rae Kang,
  • Jisoo Kang,
  • Seungjae Jang and ,
  • Seungyu Lee,
  • Dawon Kang and
  • Jeong Yoon Kim
  • + 2 authors+ 0 author

Background/Objectives: Imipenem, known as a carbapenem, is widely used in combination with Cilastatin to treat severe bacterial infections. Imipenem is a β-lactam antibiotic with potent antibacterial activity but a relatively unstable chemical s...

  • Article
  • Open Access
620 Views
28 Pages

Characterization of Phenolic Profiles Using UPLC-Q-TOF-MS/MS and NMR in the Biofunctional Fraction of Korean Winter Spinach (Spinacia oleracea L.) Leaves: Evaluation of Major Phenolics and Their Bioactivities Under Optimized Extraction Conditions

  • Eun Young Seo,
  • Eun Jeong Ko,
  • Du Yong Cho,
  • Ye Ri Jeong and ,
  • Se Hyeon Jeon,
  • Dong Hyun Park,
  • Mu Yeun Jang,
  • Jeong Yoon Kim,
  • Kye Man Cho and
  • Jin Hwan Lee
  • + 5 authors+ 0 author

This study is the first to demonstrate fluctuations in major phenolics and biofunctional properties under various extraction conditions of Korean winter spinach (Allseason cultivar) leaves. In contrast to earlier reports on summer- or greenhouse-cult...

(This article belongs to the Special Issue Innovative Processing Technologies and Their Effects on Antioxidant Activity in Plant-Derived Natural Products)
  • Feature Paper
  • Article
  • Open Access
14 Citations
6,599 Views
22 Pages

Cytotoxic Activity and Phytochemical Screening of Eco-Friendly Extracted Flavonoids from Pueraria montana var. lobata (Willd.) Sanjappa & Pradeep and Trifolium pratense L. Flowers Using HPLC-DAD-MS/HRMS

  • Saied A. Aboushanab,
  • Vadim A. Shevyrin,
  • Vsevolod V. Melekhin,
  • Elena I. Andreeva and ,
  • Oleg G. Makeev and
  • Elena G. Kovaleva
  • + 1 author+ 0 author

20 February 2023

Increasing prospective phytochemical investigations and biological activities on Pueraria lobata and Trifolium pratense flowers exhibited their nutritional (food industry) pharmaceutical (anticancer, anti-inflammatory, anti-microbial, etc.) potential...

(This article belongs to the Special Issue Bioactive Compounds from Food)
  • Article
  • Open Access
23 Citations
5,475 Views
16 Pages

In this study, eleven kinds of flavonoids were identified from F. tataricum bran (FTB) by UPLC-Q-TOF-MS, and HPLC-DAD analysis revealed that four compounds, including rutin, quercetin, kaempferol, and nicotiflorin, were the most significant component...

(This article belongs to the Special Issue Extraction and Analysis of Chemical Compositions of Natural Products and Plants)
  • Article
  • Open Access
27 Citations
5,984 Views
21 Pages

20 November 2020

Melon by-products, that currently lack high value-added applications, could be a sustainable source of bioactive compounds such as polysaccharides and antioxidants. In this work, melon peels were extracted with water to remove free sugars, and the wa...

(This article belongs to the Special Issue Recovery of High Value-Added Compounds from Food By-Product)
  • Article
  • Open Access
24 Citations
4,857 Views
22 Pages

Development of Analytical Strategies for the Determination of Olive Fruit Bioactive Compounds Using UPLC-HRMS and HPLC-DAD. Chemical Characterization of Kolovi Lesvos Variety as a Case Study

  • Ioannis Martakos,
  • Panagiota Katsianou,
  • Georgios Koulis,
  • Elvira Efstratiou and ,
  • Eleni Nastou,
  • Stylianos Nikas,
  • Marilena Dasenaki,
  • Michalis Pentogennis and
  • Nikolaos Thomaidis
  • + 4 authors+ 0 author

26 November 2021

In this study, an overall survey regarding the determination of several bioactive compounds in olive fruit is presented. Two methodologies were developed, one UPLC-Q-TOF-MS method for the determination of olive fruit phenolic compounds and one HPLC-D...

(This article belongs to the Special Issue Characterization of Olive Products from Greece)
  • Article
  • Open Access
9 Citations
2,910 Views
25 Pages

1 May 2025

Chronic alcohol consumption is a major contributor to gastric injury, yet current therapeutic strategies predominantly rely on chemical agents with limited efficacy and potential side effects. Natural products, with their multi-target biocompatibilit...

(This article belongs to the Section Nutraceuticals, Functional Foods, and Novel Foods)
  • Article
  • Open Access
5 Citations
4,695 Views
15 Pages

15 July 2025

Biogenic amines (BA) are simple organic bases of low molecular weight, formed during decarboxylation of amino acids. Ripened cheeses provide suitable conditions for the development of bacteria and production of BAs. The aim of the present study was t...

(This article belongs to the Section Food Toxicology)
  • Article
  • Open Access
52 Citations
12,972 Views
17 Pages

Chemical Composition and In Vitro Activity of Plant Extracts from Ferula communis and Dittrichia viscosa against Postharvest Fungi

  • Erjon Mamoci,
  • Ivana Cavoski,
  • Vito Simeone,
  • Donato Mondelli and ,
  • Lina Al-Bitar and
  • Pierluigi Caboni
  • + 1 author+ 0 author

22 March 2011

F. communis and D. viscosa are perennial Mediterranean weeds that have been used for different therapeutic purposes in traditional pharmacopeia. Plant extracts were obtained from air dried D. viscosa young shoots (DvA) and F. communis aerial part (Fc...

(This article belongs to the Section Natural Products Chemistry)
  • Article
  • Open Access
39 Citations
5,538 Views
15 Pages

In Vitro Antioxidant Activity Optimization of Nut Shell (Carya illinoinensis) by Extrusion Using Response Surface Methods

  • Juliana Villasante,
  • Esther Pérez-Carrillo,
  • Erick Heredia-Olea,
  • Isidoro Metón and
  • María Pilar Almajano

16 December 2019

The pecan (Carya illinoinensis) nut shell is an important byproduct of the food processing industry that has not been previously explored as an antioxidant compound. This work aims to study the effect of the extrusion temperature and screw speed on t...

(This article belongs to the Special Issue Application of Biotechnological Techniques Aimed to Obtain Bioactive Compounds from Food Industry By-Products)

of 2