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  • Article
  • Open Access
5 Citations
4,927 Views
17 Pages

Palmitic and Stearic Acids Inhibit Chaperone-Mediated Autophagy (CMA) in POMC-like Neurons In Vitro

  • Rodrigo Espinosa,
  • Karla Gutiérrez,
  • Javiera Rios,
  • Fernando Ormeño,
  • Liliana Yantén,
  • Pablo Galaz-Davison,
  • César A. Ramírez-Sarmiento,
  • Valentina Parra,
  • Amelina Albornoz and
  • Mauricio Budini
  • + 4 authors

8 March 2022

The intake of food with high levels of saturated fatty acids (SatFAs) is associated with the development of obesity and insulin resistance. SatFAs, such as palmitic (PA) and stearic (SA) acids, have been shown to accumulate in the hypothalamus, causi...

  • Article
  • Open Access
2 Citations
3,460 Views
17 Pages

The key role of the planetary boundary layer height (PBLH) in pollution, climate, and model forecasting has long been recognized. However, the observed PBLH has rarely been used to evaluate numerical weather prediction models in China. We compared th...

  • Article
  • Open Access
732 Views
19 Pages

23 October 2025

Atmospheric motion vector (AMV) products from EUMETSAT’s MetOp satellite series, including MetOp-B, MetOp-C, and the MetOp-B/C tandem (MetOp-Dual), have been assimilated at many numerical weather prediction centers worldwide. However, they have...

  • Article
  • Open Access
19 Citations
4,604 Views
12 Pages

Optimization of Properties for Alumina-Spinel Refractory Castables by CMA (CaO-MgO-Al2O3) Aggregates

  • Hai Tang,
  • Chunxue Li,
  • Jianying Gao,
  • Bruno Touzo,
  • Chunfeng Liu and
  • Wenjie Yuan

3 June 2021

Aiming at optimizing properties of alumina-spinel refractory castables, coarse corundum particles were replaced partially with the particles of a novel porous multi-component CMA (CaO-MgO-Al2O3) aggregate in the same size. Properties including the bu...

  • Feature Paper
  • Article
  • Open Access
3 Citations
3,867 Views
18 Pages

A CMA-Based Electronically Reconfigurable Dual-Mode and Dual-Band Antenna

  • Nicholas E. Russo,
  • Constantinos L. Zekios and
  • Stavros V. Georgakopoulos

17 September 2023

In this work, an electronically reconfigurable dual-band dual-mode microstrip ring antenna with high isolation is proposed. Using characteristic mode analysis (CMA), the physical characteristics of the ring antenna are revealed, and two modes are app...

  • Article
  • Open Access
1 Citations
2,113 Views
20 Pages

19 August 2024

This article aims to evaluate the performance of solar radiation forecasts produced by CMA-WSP v2.0 (version 2 of the China Meteorological Administration Wind and Solar Energy Prediction System) and to explore the application of machine learning algo...

  • Article
  • Open Access
2 Citations
3,202 Views
21 Pages

28 March 2023

Cartesian genetic programming is a popular version of classical genetic programming, and it has now demonstrated a very good performance in solving various use cases. Originally, programs evolved by using a centralized optimization approach. Recently...

  • Article
  • Open Access
3 Citations
2,120 Views
15 Pages

Wart-Treatment Efficacy Prediction Using a CMA-ES-Based Dendritic Neuron Model

  • Shuangbao Song,
  • Botao Zhang,
  • Xingqian Chen,
  • Qiang Xu and
  • Jia Qu

27 May 2023

Warts are a prevalent condition worldwide, affecting approximately 10% of the global population. In this study, a machine learning method based on a dendritic neuron model is proposed for wart-treatment efficacy prediction. To prevent premature conve...

  • Feature Paper
  • Article
  • Open Access
3 Citations
3,532 Views
22 Pages

5 January 2022

The hydrodynamic dispersion tensor (HDT) of a porous medium is a key parameter in engineering and environmental sciences. Its knowledge allows for example, to accurately predict the propagation of a pollution front induced by a surface (or subsurface...

  • Article
  • Open Access
1,397 Views
21 Pages

18 July 2025

High-resolution numerical weather prediction requires accurate cloud microphysical initial conditions to enhance forecasting capabilities for high-impact severe weather events such as convective storms. This study integrated Fengyun-2 (FY-2) geostati...

  • Article
  • Open Access
9 Citations
4,140 Views
19 Pages

Evaluation and Analysis of Absence of Homozygosity (AOH) Using Chromosome Analysis by Medium Coverage Whole Genome Sequencing (CMA-seq) in Prenatal Diagnosis

  • Yan Lü,
  • Yulin Jiang,
  • Xiya Zhou,
  • Na Hao,
  • Guizhen Lü,
  • Xiangxue Guo,
  • Ruidong Guo,
  • Wenjie Liu,
  • Chenlu Xu and
  • Qingwei Qi
  • + 5 authors

Objective: Absence of homozygosity (AOH) is a genetic characteristic known to cause human diseases mainly through autosomal recessive or imprinting mechanisms. The importance and necessity of accurate AOH detection has become more clinically signific...

  • Article
  • Open Access
773 Views
15 Pages

26 October 2025

Theoretical foundations are presented for the application of information–entropy methods from statistical physics to the determination of stellar evolutionary stages. A balance equation involving normalized conditional information and entropy i...

  • Feature Paper
  • Article
  • Open Access
2 Citations
2,147 Views
10 Pages

Hot Corrosion Behavior of Yttria-Stabilized Zirconia in the Presence of CMAS and CMAS + NaVO3 Mixture

  • Mourui Zhang,
  • Yang Feng,
  • Yong Shang,
  • Hui Peng,
  • Lei Guo,
  • Yanling Pei and
  • Shengkai Gong

20 January 2025

The aim of this paper is to study the corrosion mechanism of CaO-MgO-Al2O3-SiO2 (CMAS) powder and CMAS + NaVO3 (hereafter referred to as CN) mixed powder on a yttria-stabilized zirconia (YSZ) block at different temperatures. In this paper, the CMAS a...

  • Article
  • Open Access
1 Citations
1,509 Views
16 Pages

4 November 2024

Surface heat source (SHS) is a crucial factor affecting local weather systems. Particularly SHS on the Tibetan Plateau (TP) significantly influences East Asian atmospheric circulation and global climate. Accurate prediction of summer SHS on the TP is...

  • Article
  • Open Access
8 Citations
4,446 Views
16 Pages

16 March 2023

During the 2020/2021 winter season, three nationwide cold waves took place from 28 to 31 December 2020, as well as from 5 to 8 January and 14 to 17 January 2021. These cold waves resulted in extreme cold weather in northern and eastern China. In this...

  • Article
  • Open Access
9 Citations
2,850 Views
20 Pages

19 August 2022

In the Tropical Regional Atmospherical Model System of South China of the China Meteorological Administration (CMA-TRAMS), the skin sea surface temperature (Ts) remains fixed during the forecast time. This limits the model’s performance in desc...

  • Article
  • Open Access
1 Citations
1,375 Views
11 Pages

Unveiling the Evolution of MWC 728: Non-Conservative Mass Transfer in an FS CMa Binary

  • Nadezhda L. Vaidman,
  • Serik A. Khokhlov and
  • Aldiyar T. Agishev

We combine corrected Gaia DR3 astrometry with non-conservative MESA modelling to retrace the evolution of the FS-CMa binary MWC 728. The revised parallax sets the distance at d=1.2±0.1 kpc, leading—after Monte-Carlo error propagation&mda...

  • Article
  • Open Access
1 Citations
1,775 Views
20 Pages

Correcting Forecast Time Biases in CMA-MESO Using Himawari-9 and Time-Shift Method

  • Xingtao Song,
  • Wei Han,
  • Haofei Sun,
  • Hao Wang and
  • Xiaofeng Xu

11 February 2025

The accurate forecasting of time, intensity, and spatial distribution is fundamental to weather prediction. However, the limitations of numerical weather prediction (NWP) models, as well as uncertainties in inital conditions, often lead to temporal b...

  • Article
  • Open Access
2 Citations
2,039 Views
17 Pages

Efficient Optimization: Unveiling the Application of Ensemble Learning Combined with the CMA-ES Algorithm in Hydraulic Fracturing Design

  • Jianmin Fu,
  • Xiaofei Sun,
  • Zhengchao Ma,
  • Jiansheng Yu,
  • Qilong Zhang,
  • Bo Hao,
  • Qiang Wang,
  • Hao Hu and
  • Tianyu Wang

21 October 2024

Optimizing fracturing parameters is crucial for enhancing production and reducing costs in oil and gas exploration and development. Effectively integrating geological and engineering parameters for the automated optimization of fracturing design cont...

  • Article
  • Open Access
8 Citations
3,047 Views
13 Pages

Preparation and CMAS Wettability Investigation of CMAS Corrosion Resistant Protective Layer with Micro-Nano Double Scale Structure

  • Yihao Wang,
  • Zhenning Xu,
  • Weize Wang,
  • Chengcheng Zhang,
  • Zexin Yu,
  • Huanjie Fang and
  • Ting Yang

Solution precursor plasma spray (SPPS) can prepare thermal barrier coatings (TBCs) with nanostructures, which can modify the adhesion and wettability of molten silicate environmental deposits (CMAS) on the surface of TBCs, thereby improving the resis...

  • Article
  • Open Access
14 Citations
2,865 Views
21 Pages

9 October 2022

In this study, the polarization characteristics of the newly launched Fengyun-3E (FY-3E) microwave sounding instruments are discussed, and its data quality is also assessed using one month of observation by the double-difference method. By comparison...

  • Review
  • Open Access
8 Citations
4,863 Views
15 Pages

The Multifaceted Role of CMA in Glioma: Enemy or Ally?

  • Alessia Lo Dico,
  • Cristina Martelli,
  • Cecilia Diceglie and
  • Luisa Ottobrini

23 February 2021

Chaperone-mediated autophagy (CMA) is a catabolic pathway fundamental for cell homeostasis, by which specific damaged or non-essential proteins are degraded. CMA activity has three main levels of regulation. The first regulatory level is based on the...

  • Article
  • Open Access
3 Citations
1,572 Views
21 Pages

26 September 2023

In light of the 2020–2021 flood season in Guangdong, we conducted a comprehensive assessment of short-term precipitation forecasts generated by the ensemble prediction system (EPS) based on the China Meteorological Administration Tropical Regio...

  • Article
  • Open Access
8 Citations
2,910 Views
14 Pages

18 June 2023

Calcium–magnesium–alumina–silicate (CMAS) attack is a crucial issue for thermal–environmental barrier coatings (T/EBCs) with the ever-increasing operating temperature of turbine engines. In this study, CeO2 has been demonstrat...

  • Article
  • Open Access
5 Citations
2,443 Views
15 Pages

Damage Grading Evaluation of Thermal Barrier Coatings under CMAS Corrosion

  • Wei Liu,
  • Yangguang Liu,
  • Weize Wang,
  • Ting Yang,
  • Wenkang Zhang,
  • Chen Liu,
  • Chengcheng Zhang and
  • Shantung Tu

24 August 2023

Thermal barrier coatings (TBCs) material has excellent high-temperature resistance and heat insulation performance, which plays a vital role in improving the working efficiency and running life of the engine. During the flight, the engine will inhale...

  • Article
  • Open Access
21 Citations
5,416 Views
17 Pages

11 November 2022

A record-breaking extreme rainstorm occurred in Henan Province of China on 20 July 2021. To investigate the impacts of the Geostationary Interferometric Infrared Sounder (GIIRS) data assimilation on model analysis and forecasts of this rainfall event...

  • Article
  • Open Access
11 Citations
4,063 Views
23 Pages

Microstructure Refinement of EB-PVD Gadolinium Zirconate Thermal Barrier Coatings to Improve Their CMAS Resistance

  • Christoph Mikulla,
  • Lars Steinberg,
  • Philipp Niemeyer,
  • Uwe Schulz and
  • Ravisankar Naraparaju

Rare-earth zirconates are proven to be very effective in restricting the CMAS attack against thermal barrier coatings (TBCs) by forming quick crystalline reaction products that seal the porosity against infiltration. The microstructural effects on th...

  • Communication
  • Open Access
7 Citations
4,510 Views
8 Pages

6 December 2017

NiCr2O4 as a potential protection for thermal barrier coatings (TBCs) against the attack of molten calcium-magnesium-alumino-silicate (CMAS) was studied by a CMAS-contacting experiment. Atmospheric plasma sprayed coatings and sintered bulk materials...

  • Feature Paper
  • Article
  • Open Access
13 Citations
3,738 Views
17 Pages

10 February 2023

Thermal barrier coatings (TBCs) have been seriously threatened by calcium-magnesium-alumina-silicate (CMAS) corrosion. The search for novel ceramic coatings for TBCs with excellent resistance to CMAS corrosion is ongoing. Herein, CMAS corrosion resis...

  • Article
  • Open Access
9 Citations
3,577 Views
10 Pages

The Effect of Bond Coat Roughness on the CMAS Hot Corrosion Resistance of EB-PVD Thermal Barrier Coatings

  • Zhihang Xie,
  • Qing Liu,
  • Kuan-I. Lee,
  • Wang Zhu,
  • Liberty T. Wu and
  • Rudder T. Wu

27 April 2022

In a high-temperature, high-flame-velocity, and high-pressure gas corrosion environment, the intercolumnar pores and gaps of electron beam–physical vapor deposition (EB-PVD) thermal barrier coatings (TBCs) may serve as infiltration channels for...

  • Article
  • Open Access
14 Citations
3,240 Views
15 Pages

Interfacial Stresses of Thermal Barrier Coating with Film Cooling Holes Induced by CMAS Infiltration

  • Chenchun Chiu,
  • Shaochen Tseng,
  • Chingkong Chao,
  • Xueling Fan and
  • Weihung Cheng

1 March 2022

To obtain high gas turbine efficiency, a film cooling hole is introduced to prevent the destruction of thermal barrier coating systems (TBCs) due to hot gases. Furthermore, environmental calcium-magnesium-aluminum-silicate (CMAS) particulates plug th...

  • Article
  • Open Access
6 Citations
3,459 Views
14 Pages

21 October 2022

Environmental barrier coatings (EBCs) are used to protect ceramic-matrix composites from undesirable reactions with steam and calcia–magnesia–alumina–silicate (CMAS) particulates found in gas-turbine engine environments. Effective E...

  • Article
  • Open Access
10 Citations
3,516 Views
13 Pages

23 September 2021

The failure behavior of thermal barrier coatings (TBCs) involves multilayered systems infiltrated with calcium–magnesium–alumino-silicates (CMAS). The metastable tetragonal phase is mainly composed of 7YSZ (7 mol.% Y2O3-stabilized ZrO2), and it desta...

  • Article
  • Open Access
3 Citations
1,251 Views
15 Pages

The Growing Behavior of the Ca2Gd8(SiO4)6O2 Dense Reaction Layer in Molten CMAS at High Temperatures

  • Zijian Mo,
  • Zupeng Mo,
  • Kaisen Guo,
  • Zhiyun Yu,
  • Huan He and
  • Tianquan Liang

4 February 2025

Calcium–magnesium–alumina–silicate (CMAS), as an environmental deposit, deposits on engine components and causes serious damage to traditional thermal barrier coatings (TBCs) at high temperatures. The rare-earth silicate apatite den...

  • Article
  • Open Access
16 Citations
2,626 Views
12 Pages

16 January 2022

In this work, more than 70 wt % of ferromanganese slag (containing 40 wt % CaO) was used to synthesize high-calcium, CaO-MgO-Al2O3-SiO2 (CMAS) glass ceramics. The effect of SiO2/CaO on the structure, crystallization behavior and microstructure of hig...

  • Article
  • Open Access
16 Citations
4,542 Views
15 Pages

Influenza A viruses (IAVs) initiate infection by attaching Hemagglutinin (HA) on the viral envelope to sialic acid (SA) receptors on the cell surface. Importantly, HA of human IAVs has a higher affinity for α-2,6-linked SA receptors, and avian strain...

  • Article
  • Open Access
3 Citations
1,338 Views
13 Pages

1 December 2024

High-temperature CMAS corrosion has become a crucial factor inhibiting the further development of thermal barrier coatings (TBCs) because of the increasing service temperature of aero-engines. Herein, a novel mid-entropy rare-earth hafnate (Y0.3Gd0.3...

  • Feature Paper
  • Article
  • Open Access
3 Citations
1,254 Views
18 Pages

Integrated Microstructural and Chemical Approach for Improving CMAS Resistance in Thermal and Environmental Barrier Coatings

  • Andrew J. Wright,
  • Clara Mock,
  • Timothy Sharobem,
  • Nickolas Sotiropoulos,
  • Chris Dambra,
  • Brian Keyes and
  • Anindya Ghoshal

This study provides an investigation into the influence of surface roughness, porosity, and chemistry on the wettability and infiltration behavior of calcia-magnesia-alumino-silicates (CMASs) in thermal and environmental barrier coatings (T/EBCs) use...

  • Article
  • Open Access
1 Citations
1,015 Views
17 Pages

Study of Gd2O3-Doped La2(Zr0.7Ce0.3)2O7 Thermal Barriers for Coating Ceramic Materials for CMAS Resistance

  • Xiaowei Song,
  • Min Xie,
  • Xiaofu Qu,
  • Xiwen Song,
  • Yonghe Zhang and
  • Rende Mu

18 April 2025

The stability of thermal barrier coating (TBC) materials during service is a prerequisite for the normal operation of aircraft engines. The high-temperature corrosion of CaO–MgO–Al2O3–SiO2 (CMAS) is an important factor that affects...

  • Article
  • Open Access
1,038 Views
13 Pages

Interactions Between Sc2O3 Ceramics and Calcium–Magnesium–Alumina–Silicate (CMAS) at Elevated Temperature

  • Zupeng Mo,
  • Zijian Mo,
  • Zhiyun Yu,
  • Yifan Cheng,
  • Yiling Miao and
  • Tianquan Liang

19 February 2025

The thermochemical interactions of Sc2O3 ceramics with CMAS at 1250 °C and 1300 °C were investigated in this paper. A continuously dense reaction layer (DRL) forms on the surface of the ceramic at the beginning of the reaction within 15 min,...

  • Article
  • Open Access
6 Citations
3,447 Views
28 Pages

Unveiling the Evolutionary State of Three B Supergiant Stars: PU Gem, ϵ CMa, and η CMa

  • Julieta Paz Sánchez Arias,
  • Péter Németh,
  • Elisson Saldanha da Gama de Almeida,
  • Matias Agustin Ruiz Diaz,
  • Michaela Kraus and
  • Maximiliano Haucke

29 August 2023

We aim to combine asteroseismology, spectroscopy, and evolutionary models to establish a comprehensive picture of the evolution of Galactic blue supergiant stars (BSG). To start such an investigation, we selected three BSG candidates for our analysis...

  • Article
  • Open Access
3 Citations
3,029 Views
15 Pages

28 July 2020

Strontium zirconate (SrZrO3) commercial powder was plasma sprayed using a high-feedrate water-stabilized plasma system (WSP) torch. Coatings with a thickness of about 1 mm were produced. Now, we are concentrating on a topic never addressed for pure S...

  • Article
  • Open Access
1 Citations
2,173 Views
24 Pages

CMAS Corrosion Resistance of Plasma-Sprayed YSZ and Yb2O3-Y2O3-Co-Stabilized ZrO2 Coatings under 39–40 KW Spraying Power

  • Wenkang Zhang,
  • Wei Liu,
  • Yangguang Liu,
  • Weize Wang,
  • Ting Yang,
  • Kaibin Li,
  • Junhao Wang,
  • Xiaoqin Zhang,
  • Shilong Yang and
  • Chengcheng Zhang
  • + 1 author

24 July 2024

This study uses atmospheric plasma spraying (APS) technology to prepare thermal barrier coatings (TBCs) with yttrium-stabilized zirconia (YSZ) and Yb2O3-Y2O3-co-stabilized ZrO2 (YbYSZ) materials at different spraying powers. It analyzes the differenc...

  • Article
  • Open Access
6 Citations
3,078 Views
16 Pages

CMAS Corrosion Behavior of Nanostructured YSZ and Gd-Yb-Y-Stabilized Zirconia Coatings

  • Lanxin Zou,
  • Minghao Gao,
  • Na Xu,
  • Jia Zhang and
  • Xinchun Chang

15 September 2023

With the development of industry, the operating temperature of aero engines and gas turbines continues to increase; developing thermal barrier coatings (TBCs) with superior resistance to CaO-MgO-Al2O3-SiO2 (CMAS) corrosion has become a prominent rese...

  • Article
  • Open Access
907 Views
37 Pages

8 September 2025

Rapid urbanisation and population growth call for more Industrialised Construction (IC) as a swifter, safer, higher-quality and affordable means of delivering housing and infrastructure. Meanwhile, rising global temperatures and extreme weather patte...

  • Article
  • Open Access
6 Citations
4,101 Views
17 Pages

29 March 2022

Spiral-artery (SA) remodeling is a fundamental process during pregnancy that involves the action of cells of the initial vessel, such as vascular smooth-muscle cells (VSMCs) and endothelial cells, but also maternal immune cells and fetal extravillous...

  • Article
  • Open Access
2 Citations
2,185 Views
14 Pages

Large-Scale Ejecta of Z CMa—Proper Motion Study and New Features Discovered

  • Tiina Liimets,
  • Michaela Kraus,
  • Lydia Cidale,
  • Sergey Karpov and
  • Anthony Marston

Z Canis Majoris is a fascinating early-type binary with a Herbig Be primary and a FU Orionis-type secondary. Both of the stars exhibit sub-arcsecond jet-like ejecta. In addition, the primary is associated with the extended jet as well as with the lar...

  • Review
  • Open Access
1 Citations
1,346 Views
14 Pages

Intermediate-Mass Mergers: A New Scenario for Several FS CMa Stars

  • Daniela Korčáková,
  • Nela Dvořáková,
  • Iris Bermejo Lozano,
  • Gregg A. Wade,
  • Alicia Moranchel Basurto,
  • Pavel Kroupa,
  • Raul Ortega Chametla,
  • Colin Peter Folsom and
  • Ondrej Juhás

22 April 2025

We summarise the properties and nature of a peculiar group of B-type stars called FS CMa stars. These stars show the B[e] phenomenon, i.e., their spectra exhibit both forbidden emission lines and infrared excess. Such properties point to an extended...

  • Article
  • Open Access
15 Citations
3,735 Views
12 Pages

2 September 2022

Thermal barrier coatings (TBCs) suffer from the thermo-chemo-mechanical coupling action of thermal shock and calcium–magnesium–alumina–silicate (CMAS) corrosion. However, the failure mechanism of TBCs under the synergistic effect of...

  • Article
  • Open Access
11 Citations
4,340 Views
27 Pages

23 October 2024

Modular construction is emerging into the limelight in the construction industry as one of the front-running modern methods of construction, facilitating multiple benefits, including improved productivity. Meanwhile, Circular Economy (CE) principles...

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