- Article
Palmitic and Stearic Acids Inhibit Chaperone-Mediated Autophagy (CMA) in POMC-like Neurons In Vitro
- Rodrigo Espinosa,
- Karla Gutiérrez,
- Javiera Rios,
- Fernando Ormeño,
- Liliana Yantén,
- Pablo Galaz-Davison,
- César A. Ramírez-Sarmiento,
- Valentina Parra,
- Amelina Albornoz and
- Mauricio Budini
- + 4 authors
The intake of food with high levels of saturated fatty acids (SatFAs) is associated with the development of obesity and insulin resistance. SatFAs, such as palmitic (PA) and stearic (SA) acids, have been shown to accumulate in the hypothalamus, causi...