456,976 Results Found

(3S)-Acetoin and (2S,3S)-2,3-butanediol are important platform chemicals widely applied in the asymmetric synthesis of valuable chiral chemicals. However, their production by fermentative methods is difficult to perform. This study aimed to develop a...

Many linear diarylpentanoids and diarylheptanoids contain a β-hydroxy ketone or 1,3-diol functionality as the structural motif. Reported herein is the asymmetric synthesis of (S)-daphneolone, (S)-dihydroyashabushiketol, and formal synthesis of (...

Previous reviews have already explored the safety and bioavailability of astaxanthin, as well as its beneficial effects on human body. The great commercial potential in a variety of industries, such as the pharmaceutical and health supplement industr...

Recently, the National Oceanic and Atmospheric Administration (NOAA) performed sea surface temperature (SST) reanalysis (RAN1) from seven AVHRR/3s onboard NOAA-15 to -19 and Metop-A and -B, from 2002–present. Operational L1b data were used as input....

Hydropower plants (HPPs) create barriers across rivers and fragment aquatic ecosystems, river reaches and habitats. The reservoirs they create slow the flowing water and convert the riverine into lacustrine ecosystems. The barriers created by HPPs in...

In Mekong riparian countries, hydropower development provides energy, but also threatens biodiversity, ecosystems, food security, and an unparalleled freshwater fishery. The Sekong, Sesan, and Srepok Rivers (3S Basin) are major tributaries to the Low...

Compared with traditional cables, superconducting multi-stage cables have the natural advantages of greater transmission power and less energy loss, which have gradually attracted attention. However, conventional multi-stage cables are based on low t...

To a solution of [3S*,5S*,6S*]-1,7-dioxaspiro[5.5]undecane-3,5-diol (1) [1] (33 mg, 0.17 mmol) in dichloromethane (10 ml) was added triethylamine (54 mg, 0.53 mmol), acetic anhydride (34 mg, 0.34 mmol) and 4-dimethylaminopyridine (3 mg).[...]

A new methodology for the asymmetric synthesis of enantiomerically enriched 3-aroyl pyroglutamic acid derivatives has been developed through effective 5-exo-tet cyclization of N-chloroacetyl aroylalanines. The three-step sequence starts with the synt...

Acute myeloid leukemia (AML) frequently harbors mutations in isocitrate 1 (IDH1) and 2 (IDH2) genes, leading to the formation of the oncometabolite (2R)-hydroxyglutaric acid (2R-HG) with epigenetic consequences for AML proliferation and differentiati...

The isoflavone (3S)-vestitol, obtained from red propolis, has exhibited anti-inflammatory, antimicrobial, and anti-caries activity; however, few manuscripts deal with its anti-inflammatory mechanisms in macrophages. The objective is to elucidate the...

Cichorium endivia. L, consumed either cooked or eaten raw in salads, is a popular kind of vegetable cultivated all around the World. Its components have been widely used in folk medicine in anti-inflammatory therapy. However, the anti-cancer activity...

We recently reported that SF2312 ((1,5-dihydroxy-2-oxopyrrolidin-3-yl)phosphonic acid), a phosphonate antibiotic with a previously unknown mode of action, is a potent inhibitor of the glycolytic enzyme, Enolase. SF2312 can only be synthesized as a ra...

Carroll’s treatise on the structure of human cognitive abilities is a milestone in psychometric intelligence research. Thirty years later, Carroll’s work continues to influence research on intelligence theories and the development and int...

The reaction and the product ratio shown in the scheme was reported [1].[...]

This study focuses on the details of cascade repopulation of doubly excited triply open-shell C${}^{3+}\left(1s2s2p\right)$${}^{4}P$ and ${}^2{P}_{\pm }$ states produced in 2–18 MeV collisions of C${}^{4+}\left(1s2s{}^{3}S\right)$ with He. Such cascade calculations are necessary for the correct de...

Astaxanthin (AST) characteristics and pigment productivity of Adonis amurensis, one of the few AST-producing higher plants, have not yet been studied extensively. In this study, the geometrical and optical isomers of AST in different parts of the A. ...

A procedure to obtain relativistic expressions for photoionisation angular distribution parameters using the helicity formulation is discussed for open-shell atoms. Electric dipole and quadrupole transition matrix elements were considered in the pres...

Through choosing bread wheat genotypes that can be cultivated in less productive areas, one can increase the economic worth of those lands, and increase the area under cultivation for this strategic crop. As a result, more food sources will be availa...

A series of new organosiloxane ferroelectric liquid crystalline (FLC) materials have been synthesized, and their mesomorphic and physical properties have been characterized. Four new disiloxanes and trisiloxanes, containing biphenyl 4-hydroxybenzoat...

In order to determine the absolute configuration of naturally occurring alloxanthin, a HPLC analytical method for three stereoisomers 1a–c was established by using a chiral column. Two authentic samples, (3S,3′S)- and meso-stereoisomers 1b and 1c, we...

Iminosugars are sugar mimetics present in plants and microorganisms that were first reported in the 1960s. [...]

In this paper, we present a new concept of the generalized core orthogonality (called the C-S orthogonality) for two generalized core invertible matrices A and B. A is said to be C-S orthogonal to B if $A^{\overline{)\mathrm{S}}}B=0$ and $B{A}^{\overline{)\mathrm{S}}}=0$, where $A^{\overline{)\mathrm{S}}}$ is the generalized cor...

Most of the global population is deficient in long-chain marine omega-3s. In particular, docosahexaenoic acid (DHA), a long-chain omega-3 fatty acid, is important for brain and eye development. Additionally, DHA plays a significant role in mental hea...

Ornithine aminotransferase (OAT) is overexpressed in hepatocellular carcinoma (HCC), and we previously showed that inactivation of OAT inhibits the growth of HCC. Recently, we found that (3S,4S)-3-amino-4-fluorocyclopentenecarboxylic acid (5) was a p...

Phase transformations that take place in nanocrystalline Ag₂S silver sulfide have been systematically studied at temperatures from 298 to 893 K. The crystal structures of the polymorphic modifications α-Ag₂S, β-Ag₂S, and γ-Ag₂S of na...

The synthesis and characterization of ZnS/PMMA (poly(methyl methacrylate)), CdS/PMMA and HgS/PMMA nanocomposites are presented. Hexadecylamine (HDA)-capped ZnS, CdS and HgS nanoparticles were synthesized using dithiocarbamate single molecule precurs...

When 2-[(1S,2S)-1,2-diamino-2(2-hydroxyphenyl)ethyl]phenol (I) was reacted with 2 mole equivalents of trimethyl acetic (pivalic) anhydride in tetrahydrofuran at room temperature, 1-[(1S,2S)-1,2-bis(2-hydroxyphenyl)-2-pivaloylaminoethylamino]-2,2-dime...

The synthesis and design of low-cost visible-light-active catalysts for the photodegradation of organic dyes have been regarded as an efficient way to use solar energy in addressing environmental issues. We report the fabrication of MoS₂/CdS nanopart...

In inductive power transfer (IPT) systems, series–series (S-S) and double capacitances and inductances–series (LCCL-S) compensation topologies are widely utilized. In this study, the basic characteristics of S-S and LCCL-S are analyzed an...

Transition metal sulphide electrocatalytic materials possess the bright overall water-splitting performance of practical electrocatalytic technologies. In this study, an amethyst-like MoS₂@Ni₉S₈/Co₃S₄ rod electrocatalyst was constructed via a one-ste...

This entry first provides an overview of the historical, cultural and epistemological background that is key for Hamilton’s positions on mechanics. We consider the investigations on geometrical optics in the 17th and 18th centuries, Euler&rsquo...

Sea, Sun, and Sand (3S) are relevant and determining elements for choosing a tourist destination in Ecuador, a country with about 1200 km of coast along the Pacific Ocean. This study analyzed the market potential of the 3S in 64 beaches, 10 located i...

Starting from N-methyl-1-[(3S*,4S*)-4-(2-methylphenoxy)-3,4-dihydro-1H-isochromen-3-yl]methanamine (1) target compound 2 is prepared in a mild, direct alkylation approach with 2-fluoroethyl trifluoromethanesulfonate.

Metal sulfides-based nanomaterials have been used as a class of efficient solar driven photocatalysts. However, the H₂-production rate observed over these photocatalysts remains problematic. Here, the AgInS₂-xAg₂S-yZnS-zIn₆S₇ (x, y, z = 0 or 1) nanoc...

Wireless power transmission (WPT) has great potential for charging electric vehicles. Constant voltage (CV) and constant current (CC) are two major types of battery charging modes. In this paper, we analyze the output characteristics of series-series...

Human serum albumin (HSA) is a natural depot of amyloid-β peptide (Aβ), a key player in Alzheimer’s disease (AD). HSA and pro-inflammatory Ca²⁺-binding proteins S100A8 and S100A9 are involved in Aβ metabolism and its deposition i...

We present the synthesis and structural study of a new peptidomimetic of morphiceptin, which can formally be considered as the result of the replacement of the central proline residue of this natural analgesic drug with a subunit of (1S,2R,3S,4S,5R)-...

In a previous article we presented an argument to obtain (or rather infer) Born’s rule, based on a simple set of axioms named “Contexts, Systems and Modalities" (CSM). In this approach, there is no “emergence”, but the structu...

S100A8 and S100A9 are multifunctional proteins that can initiate various signaling pathways and modulate cell function both inside and outside immune cells, depending on their receptors, mediators, and molecular environment. They have been reported a...

Endothelial activation and cell adhesion molecules (CAMs) are exacerbated in the interaction of HIV infection and pre-eclampsia. This study compares the levels of soluble vascular cell adhesion molecule-1 (sVCAM-1), intercellular adhesion molecule-1...

New Steffensen-type inequalities are obtained by combining generalized Taylor expansions, Rabier and Pečarić extensions of Steffensen’s inequality and Faà di Bruno’s formula for higher order derivatives of the composition.

Redox post-translational modifications are derived from fluctuations in the redox potential and modulate protein function, localization, activity and structure. Amongst the oxidative reversible modifications, the S-glutathionylation of proteins was t...

Comon’s conjecture on the equality of the rank and the symmetric rank of a symmetric tensor, and Strassen’s conjecture on the additivity of the rank of tensors are two of the most challenging and guiding problems in the area of tensor dec...

In this contribution, we report on the possibility that cryptococcal protease(s) could activate the SARS-CoV-2 spike (S) protein. The S protein is documented to have a unique four-amino-acid sequence (underlined, SPRRAR↓S) at the interface betwe...

S-nitrosation has been recognized as an important mechanism of protein posttranslational regulations, based on the attachment of a nitroso group to cysteine thiols. Reversible S-nitrosation, similarly to other redox-base modifications of protein thio...

A comprehensive entomological survey was undertaken in Alipurduar District, West Bengal, from 2018 to 2020 and in 2022. This study was prompted by reported malaria cases and conducted across nine villages, seven Sub-Centres, and three Primary Health...

Introducing methodologies that promote innovation and continuous improvement in organizations is no longer optional; therefore, organizations are increasingly using methodologies based on Lean principles. Among them, the 6S tool stands out from the r...

Highly active and cost-efficient electrocatalysts for oxygen reduction reaction (ORR) are significant for developing renewable energy conversion devices. Herein, a nanocomposite Fe/ZnS-SNC electrocatalyst with an FeS and ZnS heterojunction on N,S-cod...

Most soft tissue sarcoma (STS) patients do not respond to traditional checkpoint inhibitor treatment, which may be due to infiltrating immunosuppressive tumour-associated macrophages. This study investigated the prognostic value of four serum macroph...