Announcements

We are pleased to announce that the 2024 Tu Youyou Award has been conferred upon Richard DiMarchi and Rolf Müller, in recognition of their significant contributions to natural products chemistry and medicinal chemistry.

Richard DiMarchi Indiana University, USA	Prof. Richard DiMarchi is a Distinguished Professor of Chemistry and Gill Chair in Biomolecular Sciences at Indiana University, USA. He is a member of the National Academy of Medicine and the National Inventors Hall of Fame. Dr. DiMarchi is a former Group Vice President at Eli Lilly and later at Novo Nordisk. He is recognized for his contributions to the discovery and development of rDNA-derived Humulin®, Humalog®, rGlucagon®, and Forteo®. His academic research has broadened the understanding of glucagon and incretin physiology and pioneered the discovery of single-molecule multi-mechanism agonists for the treatment of diabetes and obesity. The central element to success has been the chemical vision and technology to install within single molecules simultaneous agonism at related G-protein coupled receptors, coupled to the counter-intuitive discovery that glucagon and GIP agonism could synergize the therapeutic efficacy of GLP-1. These peptides and their conceptual approach have transformed the management of excessive body weight to a condition comparable to how hypertension, adult-onset diabetes, and excess cholesterol are medicinally managed.
“Professor DiMarchi was recognized by the 2024 Tu Youyou Award Committee members as being an exceptional leader in the medicinal chemistry of peptides and proteins of natural origin, and as a pioneer in the field of chemical biotechnology. His very important discoveries have led to breakthroughs in new drugs related to the therapy of diabetes and obesity. He has been named as an inventor on a very large number of patents, and he has had initially a highly successful scientific and administrative career in industry, which was followed by over two decades in academia as a distinguished professor.” —Prof. Dr. A. Douglas Kinghorn, Chair of the Award Committee
Rolf Müller Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Germany; Helmholtz Centre for Infections Research (HZI), Germany; Saarland University, Germany	Prof. Rolf Müller is the Founding and Managing Director of the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) and Professor of Pharmaceutical Biotechnology at Saarland University, Germany. Having received his training from the University of Bonn, he held research positions at the University of Washington, USA, and Braunschweig University of Technology, Germany, prior to his appointment as professor to Saarland University. His laboratory has dedicated itself to the exploration of bacterial natural-product biosynthetic pathways for more than 20 years and has extensive experience in working with myxobacteria and other microbial producer strains. Starting from the isolation and characterization of new microorganisms, the scope of work includes microbiology-, biotechnology-, bioinformatics-, and chemistry-based approaches to exploit these isolates as sources of new drugs with a special focus on novel anti-infectives. Müller and his team apply a variety of state-of-the-art analytical methods and biological assays to perform biological and chemical characterizations of the identified compounds. Prof. Müller has received several awards, including the prestigious Gottfried Wilhelm Leibniz Prize, the PHOENIX Pharmacy Research Award, the DECHEMA Prize, and the Inhoffen Medal, as well as being an elected member of acatech, Leopoldina, and the German Academy of Sciences and Literature.
“The 2024 Tu Youyou Award Committee members were highly impressed by the truly outstanding past and ongoing contributions of Professor Müller in both microbial natural products isolation chemistry and in biosynthesis, as well as in the development of lead compounds for their potential in treating human diseases, through his global connections with various major funding agencies. He is also a dedicated teacher who has trained numerous graduate students and postdoctoral fellows, and he has lectured on his research in countries all over the world.” —Prof. Dr. A. Douglas Kinghorn, Chair of the Award Committee

The achievements of Richard DiMarchi and Rolf Müller highlight the transformative impact of natural products chemistry and medicinal chemistry. We congratulate them and invite the global academic community and public to join us in celebrating their significant contributions.

2024 Award Committee
Committee Chair:

• Prof. Dr. A. Douglas Kinghorn, Ohio State University, USA.
  

Committee Members (listed in alphabetical order):

• Prof. Angelo Fontana, University of Naples “Federico II”, Italy;
• Prof. Binghe Wang, Georgia State University, USA;
• Dr. Diana Pinto, University of Aveiro, Portugal;
• Prof. Hideaki Kakeya, Kyoto University, Japan;
• Dr. RuAngelie Edrada-Ebel, University of Strathclyde, UK;
• Prof. Thomas Prisinzano, University of Kentucky, USA
• Prof. Wei Li, University of Tennessee Health Science Center, USA.

About the Tu Youyou Award:
The 2024 Tu Youyou Award includes a total monetary prize of 100,000 Swiss Francs and a medal for each recipient. Established in 2016 to honor the pioneering spirit of Nobel laureate Tu Youyou, the Tu Youyou Award is an international award honoring exceptional scholars dedicated to the fields of natural products chemistry and medicinal chemistry.

For further information about the award and the winners, please visit the Tu Youyou Award website.

In a time marked by rising health disparities, food insecurity, and growing inequities in access to essential resources, the need to explore how policy and research influence nutrition outcomes has never been greater.

We are delighted to welcome you to the webinar “Nutrition Policy and Programs in Educational Settings: Equitable Approaches to Food Security”. This webinar brings together distinguished academic minds, researchers, and practitioners. Through a series of concise presentations and moderated discussions, this event aims to bring together cross-disciplinary experts in nutrition policy and programs, advance dialogue on equitable food security solutions, and highlight innovative research from the Special Issue. Research shows us how good nutrition is directly linked to better academic performance, improved concentration, and long-term health outcomes. And schools are not just places of learning; they have profound influences on nutritional intake, access, and behaviors.

By studying and strengthening nutrition policies and programs in schools, we create opportunities to reduce health disparities and build the foundation for healthier families and communities. The research presented is innovative and spans multiple geographic contexts, policies, and grade levels.

Date: 22 May 2025 at 4:00 p.m. CEST | 10:00 a.m. EDT | 10:00 p.m. CST Asia
Webinar ID: 820 7490 7778
Website: https://sciforum.net/event/Nutrients-18

Register now for free!

Program:

After registering, you will receive a confirmation email containing information on how to join the webinar. Registrations with academic institutional email addresses will be prioritized.

Unable to attend? Register anyway, and we will let you know when the recording is available to watch.

Webinar Chairs and Keynote Speakers:

• Sarah Moreland-Russell, School of Public Health, Washington University in St. Louis, USA;
• Dan Ferris, Policy Education & Practice, Center for Social Development, Brown School at Washington University in St. Louis, USA;
• Gabriella Maria McLoughlin, Temple University, College of Public Health, Social and Behavioral Sciences, USA;
• Kylie Smith, Menzies Institute for Medical Research , University of Tasmania, Australia.

Relevant Special Issue:
“Nutrition Policy and Programs in Educational Settings: Equitable Approaches to Food Security”
Guest Editors: Dr. Sarah Moreland-Russell and Dr. Dan Ferris
Submission deadline: 25 August 2025

As all of the articles published in our journal are open access, you have free and unlimited access to the full texts. We welcome you to read our most highly cited papers published in 2023–2024, which are listed below:

1. “Interlinkages between Climate Change and Food Systems: The Impact on Child Malnutrition—Narrative Review”
by Carlo Agostoni, Mattia Baglioni, Adriano La Vecchia, Giulia Molari and Cristiana Berti
Nutrients 2023, 15(2), 416; https://doi.org/10.3390/nu15020416
Available online: https://www.mdpi.com/2072-6643/15/2/416

2. “Dietary Fibers in Healthy Children and in Pediatric Gastrointestinal Disorders: A Practical Guide”
by Silvia Salvatore, Maria Serena Battigaglia, Elena Murone, Eugenia Dozio, Licia Pensabene and Massimo Agosti
Nutrients 2023, 15(9), 2208; https://doi.org/10.3390/nu15092208
Available online: https://www.mdpi.com/2072-6643/15/9/2208

3. “Infantile Colic and Long-Term Outcomes in Childhood: A Narrative Synthesis of the Evidence”
by Flavia Indrio, Vanessa Nadia Dargenio, Ruggiero Francavilla, Hania Szajewska and Yvan Vandenplas
Nutrients 2023, 15(3), 615; https://doi.org/10.3390/nu15030615
Available online: https://www.mdpi.com/2072-6643/15/3/615

4. “Potential Epigenetic Effects of Human Milk on Infants’ Neurodevelopment”
by Giannoula Gialeli, Ourania Panagopoulou, Georgios Liosis and Tania Siahanidou
Nutrients 2023, 15(16), 3614; https://doi.org/10.3390/nu15163614
Available online: https://www.mdpi.com/2072-6643/15/16/3614

5. “The Ketogenic Diet in Children with Epilepsy: A Focus on Parental Stress and Family Compliance”
by Francesca Felicia Operto, Angelo Labate, Salvatore Aiello, Cristina Perillo, Valeria de Simone, Rosetta Rinaldi, Giangennaro Coppola and Grazia Maria Giovanna Pastorino
Nutrients 2023, 15(4), 1058; https://doi.org/10.3390/nu15041058
Available online: https://www.mdpi.com/2072-6643/15/4/1058

6. “Association between Food, Beverages and Overweight/Obesity in Children and Adolescents—A Systematic Review and Meta-Analysis of Observational Studies”
by Dorthe Dalstrup Jakobsen, Lea Brader and Jens Meldgaard Bruun
Nutrients 2023, 15(3), 764; https://doi.org/10.3390/nu15030764
Available online: https://www.mdpi.com/2072-6643/15/3/764

7. “Human Milk Oligosaccharides and Infant Neurodevelopment: A Narrative Review”
by Paige K. Berger, Margaret L. Ong, Lars Bode and Mandy B. Belfort
Nutrients 2023, 15(3), 719; https://doi.org/10.3390/nu15030719
Available online: https://www.mdpi.com/2072-6643/15/3/719

8. “Human Milk Microbiome—A Review of Scientific Reports”
by Agnieszka Dombrowska-Pali, Natalia Wiktorczyk-Kapischke, Agnieszka Chrustek, Dorota Olszewska-Słonina, Eugenia Gospodarek-Komkowska and Maciej W. Socha
Nutrients 2024, 16(10), 1420; https://doi.org/10.3390/nu16101420
Available online: https://www.mdpi.com/2072-6643/16/10/1420

9. “Lactose Intolerance versus Cow’s Milk Allergy in Infants: A Clinical Dilemma”
by Andy Darma, Khadijah Rizky Sumitro, Juandy Jo and Nova Sitorus
Nutrients 2024, 16(3), 414; https://doi.org/10.3390/nu16030414
Available online: https://www.mdpi.com/2072-6643/16/3/414

10. “Complementary Feeding: Tradition, Innovation and Pitfalls”
by Maria Elena Capra, Nicola Mattia Decarolis, Delia Monopoli, Serena Rosa Laudisio, Antonella Giudice, Brigida Stanyevic, Susanna Esposito and Giacomo Biasucci
Nutrients 2024, 16(5), 737; https://doi.org/10.3390/nu16050737
Available online: https://www.mdpi.com/2072-6643/16/5/737

As all of the articles published in our journal are open access, you have free and unlimited access to the full texts. We welcome you to read our most highly cited papers published in 2023–2024, which are listed below:

1. “Adipose Tissue Hyperplasia and Hypertrophy in Common and Syndromic Obesity—The Case of BBS Obesity”
by Avital Horwitz and Ruth Birk
Nutrients 2023, 15(15), 3445; https://doi.org/10.3390/nu15153445
Available online: https://www.mdpi.com/2072-6643/15/15/3445

2. “Indicaxanthin Induces Autophagy in Intestinal Epithelial Cancer Cells by Epigenetic Mechanisms Involving DNA Methylation”
by Maria Antonietta Ragusa, Flores Naselli, Ilenia Cruciata, Sara Volpes, Chiara Schimmenti, Graziella Serio, Maurizio Mauro, Mariangela Librizzi, Claudio Luparello, Roberto Chiarelli et al.
Nutrients 2023, 15(15), 3495; https://doi.org/10.3390/nu15153495
Available online: https://www.mdpi.com/2072-6643/15/15/3495

3. “Osteoarthritis in the Elderly Population: Preclinical Evidence of Nutrigenomic Activities of Flavonoids”
by Flores Naselli, Daniele Bellavia, Viviana Costa, Angela De Luca, Lavinia Raimondi, Gianluca Giavaresi and Fabio Caradonna
Nutrients 2024, 16(1), 112; https://doi.org/10.3390/nu16010112
Available online: https://www.mdpi.com/2072-6643/16/1/112

4. “Exploring the Anti-Inflammatory Effect of Inulin by Integrating Transcriptomic and Proteomic Analyses in a Murine Macrophage Cell Model”
by Federica Farabegoli, Francisco J. Santaclara, Daniel Costas, Mercedes Alonso, Ana G. Abril, Montserrat Espiñeira, Ignacio Ortea and Celina Costas
Nutrients 2023, 15(4), 859; https://doi.org/10.3390/nu15040859
Available online: https://www.mdpi.com/2072-6643/15/4/859

5. “Industrial and Ruminant Trans-Fatty Acids-Enriched Diets Differentially Modulate the Microbiome and Fecal Metabolites in C57BL/6 Mice”
by Farzad Mohammadi, Miranda Green, Emma Tolsdorf, Karine Greffard, Mickael Leclercq, Jean-François Bilodeau, Arnaud Droit, Jane Foster, Nicolas Bertrand and Iwona Rudkowska
Nutrients 2023, 15(6), 1433; https://doi.org/10.3390/nu15061433
Available online: https://www.mdpi.com/2072-6643/15/6/1433

6. “Tributyrin Mitigates Ethanol-Induced Lysine Acetylation of Histone-H3 and p65-NFκB Downregulating CCL2 Expression and Consequent Liver Inflammation and Injury”
by Smita S. Ghare, Benjamin T. Charpentier, Dushan T. Ghooray, Jingwen Zhang, Manicka V. Vadhanam, Sreelatha Reddy, Swati Joshi-Barve, Craig J. McClain and Shirish S. Barve
Nutrients 2023, 15(20), 4397; https://doi.org/10.3390/nu15204397
Available online: https://www.mdpi.com/2072-6643/15/20/4397

7. “Association of the DNA Methylation of Obesity-Related Genes with the Dietary Nutrient Intake in Children”
by Priyadarshni Patel, Vaithinathan Selvaraju, Jeganathan Ramesh Babu and Thangiah Geetha
Nutrients 2023, 15(13), 2840; https://doi.org/10.3390/nu15132840
Available online: https://www.mdpi.com/2072-6643/15/13/2840

8. “The Impact of Diet on miRNA Regulation and Its Implications for Health: A Systematic Review”
by María DeLucas, Juana Sánchez, Andreu Palou and Francisca Serra
Nutrients 2024, 16(6), 770; https://doi.org/10.3390/nu16060770
Available online: https://www.mdpi.com/2072-6643/16/6/770

9. “Personalized Nutrition: Tailoring Dietary Recommendations through Genetic Insights”
by Saiful Singar, Ravinder Nagpal, Bahram H. Arjmandi and Neda S. Akhavan
Nutrients 2024, 16(16), 2673; https://doi.org/10.3390/nu16162673
Available online: https://www.mdpi.com/2072-6643/16/16/2673

10. “Vitamin D and Aging: Central Role of Immunocompetence”
by Carsten Carlberg and Eunike Velleuer
Nutrients 2024, 16(3), 398; https://doi.org/10.3390/nu16030398
Available online: https://www.mdpi.com/2072-6643/16/3/398#

As all of the articles published in our journal are open access, you have free and unlimited access to the full texts. We welcome you to read our most highly cited papers published in 2023–2024, which are listed below:

1. “The Effects of the Mediterranean Diet on Health and Gut Microbiota”
by Thomas M. Barber, Stefan Kabisch, Andreas F. H. Pfeiffer and Martin O. Weickert
Nutrients 2023, 15(3), 500; https://doi.org/10.3390/nu15030500
Available online: https://www.mdpi.com/2072-6643/15/3/500

2. “Role of Vitamin D Deficiency in the Pathogenesis of Cardiovascular and Cerebrovascular Diseases”
by Éva Pál, Zoltán Ungvári, Zoltán Benyó and Szabolcs Várbíró
Nutrients 2023, 15(2), 334; https://doi.org/10.3390/nu15020334
Available online: https://www.mdpi.com/2072-6643/15/2/334

3. “Mediterranean Diet for Primary and Secondary Prevention of Cardiovascular Disease and Mortality: An Updated Systematic Review”
by Ana Laffond, Cristina Rivera-Picón, Pedro Manuel Rodríguez-Muñoz, Raúl Juárez-Vela, Regina Ruiz de Viñaspre-Hernández, Noelia Navas-Echazarreta and Juan Luis Sánchez-González
Nutrients 2023, 15(15), 3356; https://doi.org/10.3390/nu15153356
Available online: https://www.mdpi.com/2072-6643/15/15/3356

4. “Modern Diets and the Health of Our Planet: An Investigation into the Environmental Impacts of Food Choices”
by Kiera A. Dixon, Malia K. Michelsen and Catherine L. Carpenter
Nutrients 2023, 15(3), 692; https://doi.org/10.3390/nu15030692
Available online: https://www.mdpi.com/2072-6643/15/3/692

5. “Effect of the Ketogenic Diet on the Prophylaxis and Treatment of Diabetes Mellitus: A Review of the Meta-Analyses and Clinical Trials”
by Damian Dyńka, Katarzyna Kowalcze, Filip Ambrozkiewicz and Agnieszka Paziewska
Nutrients 2023, 15(3), 500; https://doi.org/10.3390/nu15030500
Available online: https://www.mdpi.com/2072-6643/15/3/500

6. “Is Extra Virgin Olive Oil the Critical Ingredient Driving the Health Benefits of a Mediterranean Diet? A Narrative Review”
by Mary M. Flynn, Audrey Tierney and Catherine Itsiopoulos
Nutrients 2023, 15(13), 2916; https://doi.org/10.3390/nu15132916
Available online: https://www.mdpi.com/2072-6643/15/13/2916

7. “Plant Sterols and Plant Stanols in Cholesterol Management and Cardiovascular Prevention”
by Fotios Barkas, Eirini Bathrellou, Tzortzis Nomikos, Demosthenes Panagiotakos, Evangelos Liberopoulos and Meropi D. Kontogianni
Nutrients 2023, 15(13), 2845; https://doi.org/10.3390/nu15132845
Available online: https://www.mdpi.com/2072-6643/15/13/2845

8. “Healthy Lifestyle and Cancer Risk: Modifiable Risk Factors to Prevent Cancer”
by Pasquale Marino, Mariangela Mininni, Giovanni Deiana, Graziella Marino, Rosa Divella, Ilaria Bochicchio, Alda Giuliano, Stefania Lapadula, Alessandro Rocco Lettini and Francesca Sanseverino
Nutrients 2024, 16(6), 800; https://doi.org/10.3390/nu16060800
Available online: https://www.mdpi.com/2072-6643/16/6/800

9. “Vitamin D and Dyslipidemia: Is There Really a Link? A Narrative Review”
by Antonella Al Refaie, Leonardo Baldassini, Caterina Mondillo, Michela De Vita, Elisa Giglio, Roberto Tarquini, Stefano Gonnelli and Carla Caffarelli
Nutrients 2024, 16(8), 1144; https://doi.org/10.3390/nu16081144
Available online: https://www.mdpi.com/2072-6643/16/8/1144

10. “Current Trends on the Involvement of Zinc, Copper, and Selenium in the Process of Hepatocarcinogenesis”
by Takashi Himoto and Tsutomu Masaki
Nutrients 2024, 16(4), 472; https://doi.org/10.3390/nu16040472
Available online: https://www.mdpi.com/2072-6643/16/4/472

MDPI is excited to collaborate with Toronto Metropolitan University to host an engaging Scientific Publishing Workshop aimed at empowering scholars with the knowledge and tools needed to succeed in academic publishing. This workshop will delve into the key aspects of MDPI’s open access publishing framework, offering an in-depth exploration of journal selection, the editorial workflow, and the essentials of publication ethics. Participants will also gain practical advice on improving their scientific writing and effectively addressing reviewer comments, with guidance from an experienced professional. This session promises to equip attendees with valuable skills to elevate their publishing journey.

Workshop Highlights:

• Learn How to Better Write and Structure a Research Article;
• How to Choose Where to Publish Academic Work;
• How to Respond to Reviewer Comments;
• Reasons for Rejection During Pre-Check;
• How to Navigate Through Ethics and AI Use.

Date: 15 May 2025
Time: 12:00–1:30 p.m.
Venue: Toronto Metropolitan University

Program:

As all of the articles published in our journal are open access, you have free and unlimited access to the full texts. We welcome you to read our most highly cited papers published in 2023 and 2024, which are listed below.

1. “Inverse Association between Oxidative Balance Score and Incident Type 2 Diabetes Mellitus”
by Yu-Jin Kwon, Hye-Min Park and Jun-Hyuk Lee
Nutrients 2023, 15(11), 2497; https://doi.org/10.3390/nu15112497
Available online: https://www.mdpi.com/2072-6643/15/11/2497

2. “Beta-Glucans of Cereals: Functional and Technological Properties”
by Anna Lante, Elisa Canazza and Paolo Tessari
Nutrients 2023, 15(9), 2124; https://doi.org/10.3390/nu15092124
Available online: https://www.mdpi.com/2072-6643/15/9/2124

3. “Sarcopenia and Diabetes: A Detrimental Liaison of Advancing Age”
by Giuseppe Lisco, Olga Eugenia Disoteo, Anna De Tullio, Vincenzo De Geronimo, Vito Angelo Giagulli, Fabio Monzani, Emilio Jirillo, Renato Cozzi, Edoardo Guastamacchia, Giovanni De Pergola et al.
Nutrients 2024, 16(1), 63; https://doi.org/10.3390/nu16010063
Available online: https://www.mdpi.com/2072-6643/16/1/63

4. “Visceral Adipose Tissue: The Hidden Culprit for Type 2 Diabetes”
by Sneha Dhokte and Krzysztof Czaja
Nutrients 2024, 16(7), 1015; https://doi.org/10.3390/nu16071015
Available online: https://www.mdpi.com/2072-6643/16/7/1015

5. “Efficacy of Fasting in Type 1 and Type 2 Diabetes Mellitus: A Narrative Review”
by Daniel Herz, Sandra Haupt, Rebecca Tanja Zimmer, Nadine Bianca Wachsmuth, Janis Schierbauer, Paul Zimmermann, Thomas Voit, Ulrike Thurm, Kayvan Khoramipour, Sian Rilstone et al.
Nutrients 2023, 15(16), 3525; https://doi.org/10.3390/nu15163525
Available online: https://www.mdpi.com/2072-6643/15/16/3525

6. “Impact of Dietary Fiber on Inflammation and Insulin Resistance in Older Patients: A Narrative Review”
by Michele Niero, Giulio Bartoli, Paolo De Colle, Marialaura Scarcella and Michela Zanetti
Nutrients 2023, 15(10), 2365; https://doi.org/10.3390/nu15102365
Available online: https://www.mdpi.com/2072-6643/15/10/2365

7. “Regulation of Macronutrients in Insulin Resistance and Glucose Homeostasis during Type 2 Diabetes Mellitus”
by Wanbao Yang, Wen Jiang and Shaodong Guo
Nutrients 2023, 15(21), 4671; https://doi.org/10.3390/nu15214671
Available online: https://www.mdpi.com/2072-6643/15/21/4671

8. “Effect of Aromatic Herbs and Spices Present in the Mediterranean Diet on the Glycemic Profile in Type 2 Diabetes Subjects: A Systematic Review and Meta-Analysis”
by María Carmen Garza, Sofía Pérez-Calahorra, Carmen Rodrigo-Carbó, María Antonia Sánchez-Calavera, Estíbaliz Jarauta, Rocío Mateo-Gallego, Irene Gracia-Rubio and Itziar Lamiquiz-Moneo
Nutrients 2024, 16(6), 756; https://doi.org/10.3390/nu16060756
Available online: https://www.mdpi.com/2072-6643/16/6/756

9. “Nutrition at the Intersection between Gut Microbiota Eubiosis and Effective Management of Type 2 Diabetes”
by Sevag Hamamah, Oana C. Iatcu and Mihai Covasa
Nutrients 2024, 16(2), 269; https://doi.org/10.3390/nu16020269
Available online: https://www.mdpi.com/2072-6643/16/2/269

10. “Determinants Related to Oxidative Stress Parameters in Pediatric Patients with Type 1 Diabetes Mellitus”
by Monika Grabia, Katarzyna Socha, Jolanta Soroczyńska, Artur Bossowski and Renata Markiewicz-Żukowska
Nutrients 2023, 15(9), 2084; https://doi.org/10.3390/nu15092084
Available online: https://www.mdpi.com/2072-6643/15/9/2084

As all of the articles published in our journal are open access, you have free and unlimited access to the full texts. We welcome you to read our most highly cited papers published in 2023 and 2024, which are listed below.

1. “Beyond BMI”
by George A. Bray
Nutrients 2023, 15(10), 2254; https://doi.org/10.3390/nu15102254
Available online: https://www.mdpi.com/2072-6643/15/10/2254

2. “The Genetic Basis of Childhood Obesity: A Systematic Review”
by Aikaterini Vourdoumpa, George Paltoglou and Evangelia Charmandari
Nutrients 2023, 15(6), 1416; https://doi.org/10.3390/nu15061416
Available online: https://www.mdpi.com/2072-6643/15/6/1416

3. “Browning of Adipocytes: A Potential Therapeutic Approach to Obesity”
by Vittoria Schirinzi, Carolina Poli, Chiara Berteotti and Alessandro Leone
Nutrients 2023, 15(9), 2229; https://doi.org/10.3390/nu15092229
Available online: https://www.mdpi.com/2072-6643/15/9/2229

4. “A Proposed Strategy against Obesity: How Government Policy Can Counter the Obesogenic Environment”
by Norman J. Temple
Nutrients 2023, 15(13), 2910; https://doi.org/10.3390/nu15132910
Available online: https://www.mdpi.com/2072-6643/15/13/2910

5. “Does NUCB2/Nesfatin-1 Influence Eating Behaviors in Obese Patients with Binge Eating Disorder? Toward a Neurobiological Pathway”
by Mariarita Caroleo, Elvira Anna Carbone, Biagio Arcidiacono, Marta Greco, Amedeo Primerano, Maria Mirabelli, Gilda Fazia, Marianna Rania, Marta Letizia Hribal, Luca Gallelli et al.
Nutrients 2023, 15(2), 348; https://doi.org/10.3390/nu15020348
Available online: https://www.mdpi.com/2072-6643/15/2/348

6. “The Crosstalk between Gut Microbiota and White Adipose Tissue Mitochondria in Obesity”
by Luca Colangeli, David Israel Escobar Marcillo, Valeria Simonelli, Egidio Iorio, Tommaso Rinaldi, Paolo Sbraccia, Paola Fortini and Valeria Guglielmi
Nutrients 2023, 15(7), 1723; https://doi.org/10.3390/nu15071723
Available online: https://www.mdpi.com/2072-6643/15/7/1723

7. “Depot-Dependent Impact of Time-Restricted Feeding on Adipose Tissue Metabolism in High Fat Diet-Induced Obese Male Mice”
by Theresa Bushman, Te-Yueh Lin and Xiaoli Chen
Nutrients 2023, 15(1), 238; https://doi.org/10.3390/nu15010238
Available online: https://www.mdpi.com/2072-6643/15/1/238

8. “Obesity, Dietary Patterns, and Hormonal Balance Modulation: Gender-Specific Impacts”
by Elisa Mazza, Ersilia Troiano, Yvelise Ferro, Fabrizia Lisso, Martina Tosi, Ettore Turco, Roberta Pujia and Tiziana Montalcini
Nutrients 2024, 16(11), 1629; https://doi.org/10.3390/nu16111629
Available online: https://www.mdpi.com/2072-6643/16/11/1629

9. “Influence of Bariatric Surgery on Gut Microbiota Composition and Its Implication on Brain and Peripheral Targets”
by Sevag Hamamah, Andras Hajnal and Mihai Covasa
Nutrients 2024, 16(7), 1071; https://doi.org/10.3390/nu16071071
Available online: https://www.mdpi.com/2072-6643/16/7/1071

10. “Gender Differences in Liver Steatosis and Fibrosis in Overweight and Obese Patients with Metabolic Dysfunction-Associated Steatotic Liver Disease before and after 8 Weeks of Very Low-Calorie Ketogenic Diet”
by Roberta Rinaldi, Sara De Nucci, Rossella Donghia, Rosanna Donvito, Nicole Cerabino, Martina Di Chito, Alice Penza, Francesco Pio Mongelli, Endrit Shahini, Marianna Zappimbulso et al.
Nutrients 2024, 16(10), 1408; https://doi.org/10.3390/nu16101408
Available online: https://www.mdpi.com/2072-6643/16/10/1408

World Asthma Day is held on the first Tuesday in May, aiming to improve asthma awareness and care around the world. World Asthma Day is organized by the Global Initiative for Asthma (GINA), a World Health Organization collaborative organization founded in 1993. In celebration of World Asthma Day 2025, GINA has chosen the theme “Make Inhaled Treatments Accessible for All”. GINA emphasizes the need to ensure that people with asthma can access inhaled medications that are essential both for controlling the underlying disease and treating attacks.

Asthma is one of the most common chronic non-communicable diseases that affects over 260 million people and is responsible for over 450,000 deaths each year worldwide. Most of these deaths are preventable. Inhaled corticosteroid-containing medications prevent asthma attacks by treating the underlying inflammation that causes asthma. Doctors and allied health care professionals are called upon to ensure that every person with asthma is prescribed evidence-based, essential, inhaled corticosteroid-containing medication in addition to (or in combination with) reliever medication, to prevent the continuing but avoidable morbidity and mortality from asthma.

In celebration of this day, we invite you to explore a curation of insightful articles, journals, and Special Issues across various fields, including human diseases and conditions, human nutrition, children’s health, and personalized medicine. By sharing these findings, we hope to call on everyone to increase our efforts in managing asthma to reduce and prevent attacks.

“Burden and Economic Impact of Respiratory Viral Infections in Adults Aged 60 and Older: A Focus on RSV”
by Adrián Peláez, Sara Jimeno Ruiz, Mercedes Villarreal, Manuel Gil, Inés Gutiérrez, Marta Sanz and Silvina Natalini Martínez
Diseases 2025, 13(2), 35; https://doi.org/10.3390/diseases13020035

“Long-Term Greenness Effects of Urban Forests to Reduce PM10 Concentration: Does the Impact Benefit the Population Vulnerable to Asthma?”
by Jinsuk Jeong, Chaewan Kim, Sumin Choi, Hong-Duck Sou and Chan-Ryul Park
Int. J. Environ. Res. Public Health 2025, 22(2), 167; https://doi.org/10.3390/ijerph22020167

“Sinonasal Outcomes Obtained after 2 Years of Treatment with Benralizumab in Patients with Severe Eosinophilic Asthma and CRSwNP: A “Real-Life” Observational Study”
by Eugenio De Corso, Dario Antonio Mele, Angela Rizzi, Camilla Spanu, Marco Corbò, Serena Pisciottano, Rodolfo Francesco Mastrapasqua, Silvia Baroni, Davide Paolo Porru, Gabriele De Maio et al.
J. Pers. Med. 2024, 14(9), 1014; https://doi.org/10.3390/jpm14091014

“Current Challenges in Pediatric Asthma”
by Andrija Miculinić, Iva Mrkić Kobal, Tin Kušan, Mirjana Turkalj and Davor Plavec
Children 2024, 11(6), 632; https://doi.org/10.3390/children11060632

“Prediction of Asthma Exacerbations in Children”
by Evangelia Sarikloglou, Sotirios Fouzas and Emmanouil Paraskakis
J. Pers. Med. 2024, 14(1), 20; https://doi.org/10.3390/jpm14010020

“Characterization and Factors Associated with Poor Asthma Control in Adults with Severe Eosinophilic Asthma”
by Clara Padró-Casas, María Basagaña, María Luisa Rivera-Ortún, Ignasi García-Olivé, Carlos Pollan-Guisasola, Aina Teniente-Serra, Eva Martínez-Cáceres, José-Tomás Navarro, Jorge Abad-Capa, Antoni Rosell et al.
J. Pers. Med. 2023, 13(7), 1173; https://doi.org/10.3390/jpm13071173

“Association between Single Nucleotide Polymorphisms Related to Vitamin D Metabolism and the Risk of Developing Asthma”
by Susana Rojo-Tolosa, Laura Elena Pineda-Lancheros, José María Gálvez-Navas, José Antonio Sánchez-Martínez, María Victoria González-Gutiérrez, Andrea Fernández-Alonso, Concepción Morales-García, Alberto Jiménez-Morales and Cristina Pérez-Ramírez
Nutrients 2023, 15(4), 823; https://doi.org/10.3390/nu15040823

“Racial Disparities and Common Respiratory Infectious Diseases in Children of the United States: A Systematic Review and Meta-Analysis”
by Elizabeth A. K. Jones, Amal K. Mitra and Shelia Malone
Diseases 2023, 11(1), 23; https://doi.org/10.3390/diseases11010023

“Microbiome and Asthma: Microbial Dysbiosis and the Origins, Phenotypes, Persistence, and Severity of Asthma”
by José Valverde-Molina and Luis García-Marcos
Nutrients 2023, 15(3), 486; https://doi.org/10.3390/nu15030486

“Effect of Disease Severity, Age of Child, and Clinic No-Shows on Unscheduled Healthcare Use for Childhood Asthma at an Academic Medical Center”
by Pavani Rangachari, Imran Parvez, Audrey-Ann LaFontaine, Christopher Mejias, Fahim Thawer, Jie Chen, Niharika Pathak and Renuka Mehta
Int. J. Environ. Res. Public Health 2023, 20(2), 1508; https://doi.org/10.3390/ijerph20021508

“Pulmonary Function in Children with Respiratory Symptoms” Guest Editors: Dr. Paraschiva Cherecheș-Panța and Prof. Dr. Sorin Claudiu Man Deadline for manuscript submissions: 5 August 2025	“Mechanisms of Airway Inflammation in Asthma” Guest Editor: Dr. Kathleen Haley Deadline for manuscript submissions: 20 November 2025

As all articles published in our journal are of an open access format, you have free and unlimited access to the full text. We welcome you to read our most highly cited papers published in 2023 and 2024, listed below.

1. “Sarcopenia and Cognitive Decline in Older Adults: Targeting the Muscle–Brain Axis”
by Beatrice Arosio, Riccardo Calvani, Evelyn Ferri, Hélio José Coelho-Junior, Angelica Carandina,
Federica Campanelli, Veronica Ghiglieri, Emanuele Marzetti and Anna Picca
Nutrients 2023, 15(8), 1853; https://doi.org/10.3390/nu15081853
Available online: https://www.mdpi.com/2072-6643/15/8/1853

2. “Prevalence of Malnutrition in People with Dementia in Long-Term Care: A Systematic Review and Meta-Analysis”
by Emma Perry, Karen Walton and Kelly Lambert
Nutrients 2023, 15(13), 2927; https://doi.org/10.3390/nu15132927
Available online: https://www.mdpi.com/2072-6643/15/13/2927

3. “The Integral Role of Magnesium in Muscle Integrity and Aging: A Comprehensive Review”
by Ana Carolina Remondi Souza, Andrea Rodrigues Vasconcelos, Denise Deo Dias, Geovana Komoni and José João Name
Nutrients 2023, 15(24), 5127; https://doi.org/10.3390/nu15245127
Available online: https://www.mdpi.com/2072-6643/15/24/5127

4. “A Comprehensive Review of Pathological Mechanisms and Natural Dietary Ingredients for the Management and Prevention of Sarcopenia”
by Juhae Kim, Joo-Yeon Lee and Choon Young Kim
Nutrients 2023, 15(11), 2625; https://doi.org/10.3390/nu15112625
Available online: https://www.mdpi.com/2072-6643/15/11/2625

5. “The Association of Adherence to the Mediterranean Diet with Depression in Older Adults Longitudinally Taking into Account Cognitive Status: Results from the HELIAD Study”
by Eirini Mamalaki, Eva Ntanasi, Alexandros Hatzimanolis, Maria Basta, Mary H. Kosmidis, Efthimios Dardiotis, Giorgos M. Hadjigeorgiou, Paraskevi Sakka, Nikolaos Scarmeas and Mary Yannakoulia
Nutrients 2023, 15(2), 359; https://doi.org/10.3390/nu15020359
Available online: https://www.mdpi.com/2072-6643/15/2/359

6. “The Impact of Whey Protein Supplementation on Sarcopenia Progression among the Elderly: A Systematic Review and Meta-Analysis”
by Magdalena Sylwia Kamińska, Kamila Rachubińska, Szymon Grochans, Karolina Skonieczna-Żydecka, Anna Maria Cybulska, Elżbieta Grochans and Beata Karakiewicz
Nutrients 2023, 15(9), 2039; https://doi.org/10.3390/nu15092039
Available online: https://www.mdpi.com/2072-6643/15/9/2039

7. “Photoprotective Effect of Fermented and Aged Mountain-Cultivated Ginseng Sprout (Panax ginseng) on Ultraviolet Radiation-Induced Skin Aging in a Hairless Mouse Model”
by Hee Yul Lee, Eun-Jin Kim, Du Yong Cho, Jea Gack Jung, Min Ju Kim, Jin Hwan Lee, Wanil Kim, Sang Soo Kang, Kye Man Cho and Dawon Kang
Nutrients 2023, 15(7), 1715; https://doi.org/10.3390/nu15071715
Available online: https://www.mdpi.com/2072-6643/15/7/1715

8. “Curcumin Mitigates the High-Fat High-Sugar Diet-Induced Impairment of Spatial Memory, Hepatic Metabolism, and the Alteration of the Gut Microbiome in Alzheimer’s Disease-Induced (3xTg-AD) Mice”
by Gopal Lamichhane, Jing Liu, Su-Jeong Lee, Da-Yeon Lee, Guolong Zhang and Yoo Kim
Nutrients 2024, 16(2), 240; https://doi.org/10.3390/nu16020240
Available online: https://www.mdpi.com/2072-6643/16/2/240

9. “Magnesium and the Hallmarks of Aging”
by Ligia J. Dominguez, Nicola Veronese and Mario Barbagallo
Nutrients 2024, 16(4), 496; https://doi.org/10.3390/nu16040496
Available online: https://www.mdpi.com/2072-6643/16/4/496

10. “Molecular Mechanisms of Healthy Aging: The Role of Caloric Restriction, Intermittent Fasting, Mediterranean Diet, and Ketogenic Diet—A Scoping Review”
by Roxana Surugiu, Mihaela Adela Iancu, Ștefănița Bianca Vintilescu, Mioara Desdemona Stepan, Daiana Burdusel, Amelia Valentina Genunche-Dumitrescu, Carmen-Adriana Dogaru and Gheorghe Gindrovel Dumitra
Nutrients 2024, 16(17), 2878; https://doi.org/10.3390/nu16172878
Available online: https://www.mdpi.com/2072-6643/16/17/2878