Announcements

We are pleased to announce that the article, “Exploring Gender Differences in the Effects of Diet and Physical Activity on Metabolic Parameters”, has been selected as an Editors’ Choice article. To commemorate this, we have invited one of the article's main authors, Prof. Dr. Mauro Lombardo, for an interview. You are welcome to take a read.

1. Please briefly introduce the core contributions of your paper and its academic or applied value.
The core contribution of this paper is to show that men and women do not respond in the same way to a six‑month Mediterranean, hypocaloric diet combined with regular physical activity, even when weight loss and fat mass reduction are comparable. Men achieved larger reductions in total and LDL cholesterol and in ALT, whereas women mainly increased HDL cholesterol and improved some liver markers, with fasting glucose improving similarly in both sexes. By stratifying results by gender and by type of sport (aerobic, anaerobic, combined, or no activity), we highlight that anaerobic activity is particularly effective on lipid metabolism in men, while aerobic activity yields the greatest benefits in women, especially for HDL and liver enzymes. These findings support a more personalised and gender‑sensitive prescription of diet and exercise to optimise cardiometabolic risk management in overweight patients.

2. What strategies or tools do you use during the data collection and literature review stage? Do you have any specific methods you would recommend to young scholars?
In this work, clinical data were collected in a structured obesity clinic setting, using standardised protocols for anthropometry, BIA, and biochemistry, and complemented with detailed food diaries and physical activity logs to monitor adherence over six months. For the literature review, we combined targeted searches on sex‑specific metabolism, Mediterranean diet trials, and exercise physiology, prioritising high‑quality systematic reviews and large trials and then integrating more mechanistic or niche studies. To young scholars, I would recommend: (a) defining a very narrow set of core questions before starting the search, (b) building a small “reference library” of landmark studies to anchor your reasoning, and (c) documenting inclusion/exclusion choices and search strings from the beginning, as you would for a mini‑systematic review.

3. Do you rely on any particular software, tools, or platforms during your research or writing process? (Have you used the Scilit literature platform developed by MDPI?)
For data management and analysis in this study we used SPSS for statistics, particularly for ANOVA, non‑parametric tests, and correlations, and G*Power for a priori sample size calculation. In parallel work I also routinely use Python or R for more flexible modelling and visualisation, and reference managers to keep the bibliography coherent across projects. I have explored several literature platforms, but for this specific article we mainly relied on traditional databases (PubMed, major publishers’ platforms) and standard search engines rather than Scilit; however, tools that integrate citation metrics and full‑text search, such as Scilit, can be very helpful for quickly mapping a field and identifying both seminal and very recent papers. 

4. Has your current research direction seen any new expansions? What cutting-edge directions or potential hotspots do you think are worth paying attention to in this field in the future?
Building on this study, our research is expanding in three main directions: first, deeper characterisation of body composition and fat distribution (e.g., visceral vs subcutaneous) to better explain gender differences in metabolic response; second, integration of behavioural and adherence metrics to understand why some individuals exceed weight‑loss predictions from dynamic models like CALERIE and POUNDS Lost; and third, exploration of interactions between lifestyle interventions and emerging pharmacological treatments for obesity and diabetes. Looking ahead, I see at least three hotspots: (a) precision lifestyle medicine, with diet and exercise prescriptions tailored by sex, age, and metabolic phenotype; (b) combinations of Mediterranean‑style patterns with other novel plant-based dietary frameworks; and (c) the use of digital tools and wearables to continuously monitor lifestyle and metabolic responses in real life.

5. What factors do you usually consider when choosing a journal to submit to? What suggestions or expectations do you have for journals like ours?
When choosing a journal, I usually consider scope alignment, methodological rigour, transparency of the peer‑review process, indexing/visibility, and reasonable publication timelines, as well as the journal’s openness to nuanced topics such as sex differences and personalised interventions. For journals like Nutrients, my main expectations are: clear and consistent standards for study design and reporting, a strong stance on open science (data and methods), and careful handling of conflicts of interest and industry‑linked content. I would also welcome continued attention to statistical robustness and encouragement of registered protocols and trial registration, as we did with ClinicalTrials.

6. We are also actively participating in conferences or inviting scholars to organise webinars. Do you have any conference recommendations related to Nutrients, or would you like to host a webinar?
In recent years I had the opportunity to serve as Conference Chair for two events strongly aligned with the scope of Nutrients: the 5th International Online Conference on Nutrients (2025), focused on sport nutrition, and the 4th International Electronic Conference on Nutrients (2024) on plant‑based nutrition, innovation, health, and sustainable food systems. Both conferences were very successful, with more than 1000 registered participants and around 100 abstracts submitted, and they confirmed the strong interest of the scientific community in lifestyle‑based prevention and personalised nutrition. These experiences were extremely positive from both the scientific and organisational perspectives, and I would be pleased to consider further collaborations of this kind, including webinars or future online conferences in areas related to sport nutrition, the Mediterranean diet, and gender‑specific cardiometabolic prevention.

7. Many scholars are concerned about how to balance research output and personal life. Do you have any special experience in time management or energy allocation that you could share? Finally, could you please share your recent submission or publication plans? Have you considered submitting your future research to Nutrients?
Balancing research and personal life is always challenging, so I try to work on a few simple principles rather than a perfect system. I protect blocks of uninterrupted time for “deep work” (data analysis, writing, reviewing) and cluster more routine tasks—emails, administrative work, short meetings—into specific slots so they do not fragment the day. I also plan the week rather than the day, with 2–3 realistic priorities, accepting that some days are clinically heavy and leaving research tasks for other windows. Finally, I deliberately schedule non‑academic time with family and personal interests as “fixed appointments”, and I also play bass in a rock band!  And I keep 2 hours on alternate days for running and bodyweight exercises, which helps me to disconnect mentally and maintain energy over the long term.
Regarding current and future publications, we have a manuscript in Nutrients that has received positive reviews and is now awaiting the Academic Editor’s decision: “Dietary Behavior Clustering and Cardiovascular Risk Markers in a Large Population Cohort”, submitted to Nutrients. In this study, we used principal component analysis on eating behaviour variables in 2,461 adults to identify four profiles—structured, social, irregular, and disordered eaters—and showed that more disorganised eating is associated with higher BMI and fat mass and with lower adherence to cardioprotective food choices. This work continues the same line of research on lifestyle, behaviour, and cardiometabolic risk and fits very well with the aims of Nutrients, so I certainly plan to consider Nutrients as a preferred venue for future studies arising from these projects.

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1. “Bioactive Components of Human Milk and Their Impact on Child’s Health and Development, Literature Review”
by Hubert Szyller, Katarzyna Antosz, Joanna Batko, Agata Mytych, Marta Dziedziak, Martyna Wrześniewska, Joanna Braksator and Tomasz Pytrus
Nutrients 2024, 16(10), 1487; https://doi.org/10.3390/nu16101487
Available online: https://www.mdpi.com/2072-6643/16/10/1487

2. “Selected Flavonols Targeting Cell Death Pathways in Cancer Therapy: The Latest Achievements in Research on Apoptosis, Autophagy, Necroptosis, Pyroptosis, Ferroptosis, and Cuproptosis”
by Dominika Wendlocha, Robert Kubina, Kamil Krzykawski and Aleksandra Mielczarek-Palacz
Nutrients 2024, 16(8), 1201; https://doi.org/10.3390/nu16081201
Available online: https://www.mdpi.com/2072-6643/16/8/1201

3. “Bioavailability of Anthocyanins: Whole Foods versus Extracts”
by Ravish Kumkum, Kathryn Aston-Mourney, Bryony A. McNeill, Damián Hernández and Leni R. Rivera
Nutrients 2024, 16(10), 1403; https://doi.org/10.3390/nu16101403
Available online: https://www.mdpi.com/2072-6643/16/10/1403

4. “Beneficial Effects of Spirulina Supplementation in the Management of Cardiovascular Diseases”
by Valeria Prete, Angela Carmelita Abate, Paola Di Pietro, Massimiliano De Lucia, Carmine Vecchione and Albino Carrizzo
Nutrients 2024, 16(5), 642; https://doi.org/10.3390/nu16050642
Available online: https://www.mdpi.com/2072-6643/16/5/642

5. “The Anticancer Effects and Therapeutic Potential of Kaempferol in Triple-Negative Breast Cancer”
by Sukhmandeep Kaur, Patricia Mendonca and Karam F. A. Soliman
Nutrients 2024, 16(15), 2392; https://doi.org/10.3390/nu16152392
Available online: https://www.mdpi.com/2072-6643/16/15/2392

6. “Potential Strategies for Overcoming Drug Resistance Pathways Using Propolis and Its Polyphenolic/Flavonoid Compounds in Combination with Chemotherapy and Radiotherapy”
by Nada Oršolić and Maja Jazvinšćak Jembrek
Nutrients 2024, 16(21), 3741; https://doi.org/10.3390/nu16213741
Available online: https://www.mdpi.com/2072-6643/16/21/3741

7. “Improving the Effect of Ferulic Acid on Inflammation and Insulin Resistance by Regulating the JNK/ERK and NF-κB Pathways in TNF-α-Treated 3T3-L1 Adipocytes”
by Jae Eun Park and Ji Sook Han
Nutrients 2024, 16(2), 294; https://doi.org/10.3390/nu16020294
Available online: https://www.mdpi.com/2072-6643/16/2/294

8. “Clinical Insights into Non-Alcoholic Fatty Liver Disease and the Therapeutic Potential of Flavonoids: An Update”
by Aleksandra Kozłowska
Nutrients 2025, 17(6), 956; https://doi.org/10.3390/nu17060956
Available online: https://www.mdpi.com/2072-6643/17/6/956

9. “The Neuroprotective Role of Curcumin: From Molecular Pathways to Clinical Translation—A Narrative Review”
by Andrea Lehoczki, Mónika Fekete, Tamás Jarecsny, Virág Zábó, Ágnes Szappanos, Tamás Csípő, Ágnes Lipécz, Dávid Major, Vince Fazekas-Pongor, Péter Varga et al.
Nutrients 2025, 17(17), 2884; https://doi.org/10.3390/nu17172884
Available online: https://www.mdpi.com/2072-6643/17/17/2884

10. “Nutritional Status of Vitamin E and Its Association with Metabolic Health in Adults”
by Kacper Szewczyk, Joanna Bryś, Rita Brzezińska and Magdalena Górnicka
Nutrients 2025, 17(3), 408; https://doi.org/10.3390/nu17030408
Available online: https://www.mdpi.com/2072-6643/17/3/408

1. “Gender-Specific Bile Acid Profiles in Non-Alcoholic Fatty Liver Disease”
by Julia Fitzinger, Giovanny Rodriguez-Blanco, Markus Herrmann, Andrea Borenich, Rudolf Stauber, Elmar Aigner and Harald Mangge
Nutrients 2024, 16(2), 250; https://doi.org/10.3390/nu16020250
Available online: https://www.mdpi.com/2072-6643/16/2/250

2. “High-Density Lipoprotein Metabolism and Function in Cardiovascular Diseases: What about Aging and Diet Effects?”
by Mojgan Morvaridzadeh, Nada Zoubdane, Javad Heshmati, Mehdi Alami, Hicham Berrougui and Abdelouahed Khalil
Nutrients 2024, 16(5), 653; https://doi.org/10.3390/nu16050653
Available online: https://www.mdpi.com/2072-6643/16/5/653

3. “The Cardioprotective Effects of Polyunsaturated Fatty Acids Depends on the Balance Between Their Anti- and Pro-Oxidative Properties”
by Malgorzata Sidorkiewicz
Nutrients 2024, 16(22), 3937; https://doi.org/10.3390/nu16223937
Available online: https://www.mdpi.com/2072-6643/16/22/3937

4. “4-Hydroxynonenal from Mitochondrial and Dietary Sources Causes Lysosomal Cell Death for Lifestyle-Related Diseases”
by Tetsumori Yamashima
Nutrients 2024, 16(23), 4171; https://doi.org/10.3390/nu16234171
Available online: https://www.mdpi.com/2072-6643/16/23/4171

5. “Nutritional Status and Recurrent Major Cardiovascular Events Following Acute Myocardial Infarction—A Follow-Up Study in a Primary Percutaneous Coronary Intervention Center”
by Maria Czinege, Vasile-Bogdan Halațiu, Victoria Nyulas, Liliana-Oana Cojocariu, Bianca Ion, Violeta Mașca, Constantin Țolescu and Theodora Benedek
Nutrients 2024, 16(7), 1088; https://doi.org/10.3390/nu16071088
Available online: https://www.mdpi.com/2072-6643/16/7/1088

6. “Effects of Xanthine Oxidase Inhibition by Febuxostat on Lipid Profiles of Patients with Hyperuricemia: Insights from Randomized PRIZE Study”
by Yuichi Saito, Atsushi Tanaka, Hisako Yoshida, Hitoshi Nakashima, Noriko Ban, Munehide Matsuhisa, Yoshio Kobayashi, Koichi Node and on behalf of the PRIZE Study Investigators.
Nutrients 2024, 16(14), 2324; https://doi.org/10.3390/nu16142324
Available online: https://www.mdpi.com/2072-6643/16/14/2324

7. “Characteristics, Physiopathology and Management of Dyslipidemias in Pregnancy: A Narrative Review”
by Elena Formisano, Elisa Proietti, Giuseppina Perrone, Valentina Demarco, Paola Galoppi, Claudia Stefanutti and Livia Pisciotta
Nutrients 2024, 16(17), 2927; https://doi.org/10.3390/nu16172927
Available online: https://www.mdpi.com/2072-6643/16/17/2927

8. “Body Mass Index and Cardiovascular Risk Markers: A Large Population Analysis”
by Bela F. Asztalos, Giuseppina Russo, Lihong He and Margaret R. Diffenderfer
Nutrients 2025, 17(5), 740; https://doi.org/10.3390/nu17050740
Available online: https://www.mdpi.com/2072-6643/17/5/740

9. “Dietary Lipids, Gut Microbiota, and Their Metabolites: Insights from Recent Studies”
by Farzad Mohammadi and Iwona Rudkowska
Nutrients 2025, 17(4), 639; https://doi.org/10.3390/nu17040639
Available online: https://www.mdpi.com/2072-6643/17/4/639

10. “Changes in Oxidative Stress, Inflammatory Markers, and Lipid Profile After a 6-Week High-Antioxidant-Capacity Dietary Intervention in CVD Patients”
by Magdalena Czlapka-Matyasik, Lidia Wadolowska, Paweł Gut and Anna Gramza-Michałowska
Nutrients 2025, 17(5), 806; https://doi.org/10.3390/nu17050806
Available online: https://www.mdpi.com/2072-6643/17/5/806

1. “Diagnostic Criteria and Measurement Techniques of Sarcopenia: A Critical Evaluation of the Up-to-Date Evidence”
by Gavriela Voulgaridou, Stefanos Tyrovolas, Paraskevi Detopoulou, Despoina Tsoumana, Mariella Drakaki, Thomas Apostolou, Ioanna P. Chatziprodromidou, Dimitrios Papandreou, Constantinos Giaginis and Sousana K. Papadopoulou
Nutrients 2024, 16(3), 436; https://doi.org/10.3390/nu16030436
Available online: https://www.mdpi.com/2072-6643/16/3/436

2. “Emerging Targets and Treatments for Sarcopenia: A Narrative Review”
by Stefano Cacciatore, Riccardo Calvani, Ilaria Esposito, Claudia Massaro, Giordana Gava, Anna Picca, Matteo Tosato, Emanuele Marzetti and Francesco Landi
Nutrients 2024, 16(19), 3271; https://doi.org/10.3390/nu16193271
Available online: https://www.mdpi.com/2072-6643/16/19/3271

3. “Advancing the Understanding of Malnutrition in the Elderly Population: Current Insights and Future Directions”
by Anna Tomasiewicz, Jacek Polański and Wojciech Tański
Nutrients 2024, 16(15), 2502; https://doi.org/10.3390/nu16152502
Available online: https://www.mdpi.com/2072-6643/16/15/2502

4. “Adherence to a Mediterranean Diet Is Inversely Associated with Anxiety and Stress but Not Depression: A Cross-Sectional Analysis of Community-Dwelling Older Australians”
by Lisa Allcock, Evangeline Mantzioris and Anthony Villani
Nutrients 2024, 16(3), 366; https://doi.org/10.3390/nu16030366
Available online: https://www.mdpi.com/2072-6643/16/3/366

5. “The Relationship between Mushroom Intake and Cognitive Performance: An Epidemiological Study in the European Investigation of Cancer—Norfolk Cohort (EPIC-Norfolk)”
by Sara Cha, Lynne Bell and Claire M. Williams
Nutrients 2024, 16(3), 353; https://doi.org/10.3390/nu16030353
Available online: https://www.mdpi.com/2072-6643/16/3/353

6. “The Relationship Between Gut Microbiota, Muscle Mass and Physical Function in Older Individuals: A Systematic Review”
by David J. Barry, Sam S. X. Wu and Matthew B. Cooke
Nutrients 2025, 17(1), 81; https://doi.org/10.3390/nu17010081
Available online: https://www.mdpi.com/2072-6643/17/1/81

7. “Prevention, Assessment, and Management of Malnutrition in Older Adults with Early Stages of Cognitive Disorders”
by Irene Loda, Emanuela D’Angelo, Emanuele Marzetti and Hanna Kerminen
Nutrients 2024, 16(11), 1566; https://doi.org/10.3390/nu16111566
Available online: https://www.mdpi.com/2072-6643/16/11/1566

8. “The Antiaging Potential of Dietary Plant-Based Polyphenols: A Review on Their Role in Cellular Senescence Modulation”
by Matteo Centonze, Emanuela Aloisio Caruso, Valentina De Nunzio, Miriam Cofano, Ilenia Saponara, Giuliano Pinto and Maria Notarnicola
Nutrients 2025, 17(10), 1716; https://doi.org/10.3390/nu17101716
Available online: https://www.mdpi.com/2072-6643/17/10/1716

9. “Associations Between MASLD, Ultra-Processed Food and a Mediterranean Dietary Pattern in Older Adults”
by Isabella Commins, Daniel Clayton-Chubb, Jessica A. Fitzpatrick, Elena S. George, Hans G. Schneider, Aung Zaw Zaw Phyo , Ammar Majeed, Natasha Janko, Nicole Vaughan, Robyn L. Woods et al.
Nutrients 2025, 17(9), 1415; https://doi.org/10.3390/nu17091415
Available online: https://www.mdpi.com/2072-6643/17/9/1415

1. “The Role of Nutrition on Thyroid Function”
by Anna-Mariia Shulhai, Roberta Rotondo, Maddalena Petraroli, Viviana Patianna, Barbara Predieri, Lorenzo Iughetti, Susanna Esposito and Maria Elisabeth Street
Nutrients 2024, 16(15), 2496; https://doi.org/10.3390/nu16152496
Available online: https://www.mdpi.com/2072-6643/16/15/2496

2. “The Immunomodulatory Effects of Selenium: A Journey from the Environment to the Human Immune System”
by Rebecka A. Sadler, Bonnie A. Mallard, Umesh K. Shandilya, Mohammed A. Hachemi and Niel A. Karrow
Nutrients 2024, 16(19), 3324; https://doi.org/10.3390/nu16193324
Available online: https://www.mdpi.com/2072-6643/16/19/3324

3. “The Efficacy of Multivitamin, Vitamin A, Vitamin B, Vitamin C, and Vitamin D Supplements in the Prevention and Management of COVID-19 and Long-COVID: An Updated Systematic Review and Meta-Analysis of Randomized Clinical Trials”
by Alessandra Sinopoli, Antonio Sciurti, Claudia Isonne, Maria Mercedes Santoro and Valentina Baccolini
Nutrients 2024, 16(9), 1345; https://doi.org/10.3390/nu16091345
Available online: https://www.mdpi.com/2072-6643/16/9/1345

4. “Relationship of Low Vitamin B6 Status with Sarcopenia, Frailty, and Mortality: A Narrative Review”
by Norihisa Kato, Akiko Kimoto, Peipei Zhang, Chanikan Bumrungkit, Sajith Karunaratne, Noriyuki Yanaka and Thanutchaporn Kumrungsee
Nutrients 2024, 16(1), 177; https://doi.org/10.3390/nu16010177
Available online: https://www.mdpi.com/2072-6643/16/1/177

5. “Nutrition, Vitamin D, and Calcium in Elderly Patients before and after a Hip Fracture and Their Impact on the Musculoskeletal System: A Narrative Review”
by Luisella Cianferotti, Giuseppe Bifolco, Carla Caffarelli, Gherardo Mazziotti, Silvia Migliaccio,
Nicola Napoli, Carmelinda Ruggiero and Cristiana Cipriani
Nutrients 2024, 16(11), 1773; https://doi.org/10.3390/nu16111773
Available online: https://www.mdpi.com/2072-6643/16/11/1773

6. “Multifaceted Roles of Vitamin D for Diabetes: From Immunomodulatory Functions to Metabolic Regulations”
by Chan Yoon Park, Sunhye Shin and Sung Nim Han
Nutrients 2024, 16(18), 3185; https://doi.org/10.3390/nu16183185
Available online: https://www.mdpi.com/2072-6643/16/18/3185

7. “The Antioxidant Potential of Vitamins and Their Implication in Metabolic Abnormalities”
by Panagiotis Theodosis-Nobelos and Eleni A. Rekka
Nutrients 2024, 16(16), 2740; https://doi.org/10.3390/nu16162740
Available online: https://www.mdpi.com/2072-6643/16/16/2740

8. “Vitamins K2 and D3 Improve Long COVID, Fungal Translocation, and Inflammation: Randomized Controlled Trial”
by Ornina Atieh, Joviane Daher, Jared C. Durieux, Marc Abboud, Danielle Labbato, Jhony Baissary,
Ziad Koberssy, Kate Ailstock, Morgan Cummings, Nicholas T. Funderburg et al.
Nutrients 2025, 17(2), 304; https://doi.org/10.3390/nu17020304
Available online: https://www.mdpi.com/2072-6643/17/2/304

9. ”Vitamin D and Colorectal Cancer Prevention: Immunological Mechanisms, Inflammatory Pathways, and Nutritional Implications”
by Mónika Fekete, Andrea Lehoczki, Ágnes Szappanos, Virág Zábó, Csilla Kaposvári, Alpár Horváth, Árpád Farkas, Vince Fazekas-Pongor, Dávid Major, Ágnes Lipécz et al.
Nutrients 2025, 17(8), 1351; https://doi.org/10.3390/nu17081351
Available online: https://www.mdpi.com/2072-6643/17/8/1351

1. “Importance of Energy, Dietary Protein Sources, and Amino Acid Composition in the Regulation of Metabolism: An Indissoluble Dynamic Combination for Life”
by Giovanni Corsetti, Evasio Pasini, Tiziano M. Scarabelli, Claudia Romano, Arashpreet Singh, Carol C. Scarabelli and Francesco S. Dioguardi
Nutrients 2024, 16(15), 2417; https://doi.org/10.3390/nu16152417
Available online: https://www.mdpi.com/2072-6643/16/15/2417

2. “Exploring the Role of Lactoferrin in Managing Allergic Airway Diseases among Children: Unrevealing a Potential Breakthrough”
by Alessandra Gori, Giulia Brindisi, Maria Daglia, Michele Miraglia del Giudice, Giulio Dinardo, Alessandro Di Minno, Lorenzo Drago, Cristiana Indolfi, Matteo Naso , Chiara Trincianti et al.
Nutrients 2024, 16(12), 1906; https://doi.org/10.3390/nu16121906
Available online: https://www.mdpi.com/2072-6643/16/12/1906

3. “Hyperhomocysteinemia: Underlying Links to Stroke and Hydrocephalus, with a Focus on Polyphenol-Based Therapeutic Approaches”
by Carmen Ortiz-Salguero, Marina Romero-Bernal, Ángela González-Díaz, Elaheh Sobh Doush, Carmen del Río, Miriam Echevarría and Joan Montaner
Nutrients 2025, 17(1), 40; https://doi.org/10.3390/nu17010040
Available online: https://www.mdpi.com/2072-6643/17/1/40

4. “The Role of S-Glutathionylation in Health and Disease: A Bird’s Eye View”
by Luca Federici, Michele Masulli, Vincenzo De Laurenzi and Nerino Allocati
Nutrients 2024, 16(16), 2753; https://doi.org/10.3390/nu16162753
Available online: https://www.mdpi.com/2072-6643/16/16/2753

5. “Effectiveness of High-Protein Energy-Dense Oral Supplements on Patients with Malnutrition Using Morphofunctional Assessment with AI-Assisted Muscle Ultrasonography: A Real-World One-Arm Study”
by Juan José López-Gómez, David Primo-Martín, Angela Cebria, Olatz Izaola-Jauregui, Eduardo Jorge Godoy, Paloma Pérez-López, Rebeca Jiménez Sahagún, Beatriz Ramos Bachiller, Jaime González Gutiérrez and Daniel A. De Luis Román
Nutrients 2024, 16(18), 3136; https://doi.org/10.3390/nu16183136
Available online: https://www.mdpi.com/2072-6643/16/18/3136

6. “The Potential of the Adzuki Bean (Vigna angularis) and Its Bioactive Compounds in Managing Type 2 Diabetes and Glucose Metabolism: A Narrative Review”
by Shu Hang Kwan and Elvira Gonzalez de Mejia
Nutrients 2024, 16(2), 329; https://doi.org/10.3390/nu16020329
Available online: https://www.mdpi.com/2072-6643/16/2/329

7. “Olive (Olea europaea L.) Seed as New Source of Cholesterol-Lowering Bioactive Peptides: Elucidation of Their Mechanism of Action in HepG2 Cells and Their Trans-Epithelial Transport in Differentiated Caco-2 Cells”
by Martina Bartolomei, Jianqiang Li, Anna Laura Capriotti, Melissa Fanzaga, Lorenza d’Adduzio,
Aldo Laganà, Andrea Cerrato, Nadia Mulinacci, Lorenzo Cecchi, Carlotta Bollati et al.
Nutrients 2024, 16(3), 371; https://doi.org/10.3390/nu16030371
Available online: https://www.mdpi.com/2072-6643/16/3/371

8. “L-Arginine and Nitric Oxide in Vascular Regulation—Experimental Findings in the Context of Blood Donation”
by Natalia Kurhaluk and Halina Tkaczenko
Nutrients 2025, 17(4), 665; https://doi.org/10.3390/nu17040665
Available online: https://www.mdpi.com/2072-6643/17/4/665

9. ”Proteins and Amino Acids from Edible Insects for the Human Diet—A Narrative Review Considering Environmental Sustainability and Regulatory Challenges”
by Lukas Nachtigall, Tilman Grune and Daniela Weber
Nutrients 2025, 17(7), 1245; https://doi.org/10.3390/nu17071245
Available online: https://www.mdpi.com/2072-6643/17/7/1245

As all the articles published in Nutrients (ISSN: 2072-6643) use an open access format, you have free and unlimited access to the full text. We welcome you to read our most highly cited papers published in 2024 and 2025, listed below:

1. “Chlorogenic Acid: A Systematic Review on the Biological Functions, Mechanistic Actions, and Therapeutic Potentials”
by Vi Nguyen, Elaine G. Taine, Dehao Meng, Taixing Cui and Wenbin Tan
Nutrients 2024, 16(7), 924; https://doi.org/10.3390/nu16070924
Available online: https://www.mdpi.com/2072-6643/16/7/924

2. “Gluten-Free Diet and Other Celiac Disease Therapies: Current Understanding and Emerging Strategies”
by Anna Maria Mazzola, Irene Zammarchi, Maria Chiara Valerii, Enzo Spisni, Ilaria Maria Saracino, Francesco Lanzarotto and Chiara Ricci
Nutrients 2024, 16(7), 1006; https://doi.org/10.3390/nu16071006
Available online: https://www.mdpi.com/2072-6643/16/7/1006

3. “Histamine Intolerance: Symptoms, Diagnosis, and Beyond”
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Available online: https://www.mdpi.com/2072-6643/16/8/1219

4. “Cow’s Milk: A Benefit for Human Health? Omics Tools and Precision Nutrition for Lactose Intolerance Management”
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Nutrients 2024, 16(2), 320; https://doi.org/10.3390/nu16020320
Available online: https://www.mdpi.com/2072-6643/16/2/320

5. “Exploring the Link between Lifestyle, Inflammation, and Insulin Resistance through an Improved Healthy Living Index”
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Nutrients 2024, 16(3), 388; https://doi.org/10.3390/nu16030388
Available online: https://www.mdpi.com/2072-6643/16/3/388

6. “Zingiber Officinale Roscoe: The Antiarthritic Potential of a Popular Spice—Preclinical and Clinical Evidence”
by Joanna Szymczak, Bogna Grygiel-Górniak and Judyta Cielecka-Piontek
Nutrients 2024, 16(5), 741; https://doi.org/10.3390/nu16050741
Available online: https://www.mdpi.com/2072-6643/16/5/741

7. “Efficacy of Dietary Therapy for Eosinophilic Esophagitis in Children and Adults: An Updated Systematic Review and Meta-Analysis”
by Ángel Arias, Antonio Tejera-Muñoz, Lucía Gutiérrez-Ramírez, Javier Molina-Infante and Alfredo J. Lucendo, on behalf of the EUREOS Guidelines Committee
Nutrients 2024, 16(5), 741; https://doi.org/10.3390/nu16050741
Available online: https://www.mdpi.com/2072-6643/16/14/2231

8. “Non-Celiac Gluten/Wheat Sensitivity—State of the Art: A Five-Year Narrative Review”
by Francesca Manza, Lisa Lungaro, Anna Costanzini, Fabio Caputo, Antonio Carroccio, Pasquale Mansueto, Aurelio Seidita, Suneil A. Raju, Umberto Volta, Roberto De Giorgio et al.
Nutrients 2025, 17(2), 220; https://doi.org/10.3390/nu17020220
Available online: https://www.mdpi.com/2072-6643/17/2/220

9. “The Epithelial Barrier Hypothesis in Food Allergies: The State of the Art”
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Available online: https://www.mdpi.com/2072-6643/17/6/1014

10. “Unlocking the Power of the Mediterranean Diet: Two in One—Dual Benefits for Rheumatic and Thyroid Autoimmune Diseases”
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“Personalized Nutrition: Tailoring Dietary Recommendations through Genetic Insights”
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“The Impact of Diet on miRNA Regulation and Its Implications for Health: A Systematic Review”
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“Exploring the Interplay of Genetics and Nutrition in the Rising Epidemic of Obesity and Metabolic Diseases”
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Nutrients 2024, 16(20), 3562; https://doi.org/10.3390/nu16203562
Available online: https://www.mdpi.com/2072-6643/16/20/3562

“Synergistic Effects of Fructose and Food Preservatives on Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): From Gut Microbiome Alterations to Hepatic Gene Expression”
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Nutrients 2024, 16(21), 3722; https://doi.org/10.3390/nu16213722
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“Deciphering the Interplay between Genetic Risk Scores and Lifestyle Factors on Individual Obesity Predisposition”
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Nutrients 2024, 16(9), 1296; https://doi.org/10.3390/nu1691296
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“A Systematic Review of the Gene–Lifestyle Interactions on Metabolic Disease-Related Outcomes in Arab Populations”
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Nutrients 2024, 16(15), 2519; https://doi.org/10.3390/nu16152519
Available online: https://www.mdpi.com/2072-6643/16/15/2519

“A Nutrigenomic View on the Premature-Aging Disease Fanconi Anemia”
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Nutrients 2024, 16(14), 2271; https://doi.org/10.3390/nu16142271
Available online: https://www.mdpi.com/2072-6643/16/14/2271

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by Huixin Wu, Brittany L. Witt, William J. van der Pol, Casey D. Morrow, Lennard W. Duck and Trygve O. Tollefsbol
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“The Impact of Tartrazine on DNA Methylation, Histone Deacetylation and Genomic Stability in Human Cell Lines”
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Nutrients 2025, 17(5), 913; https://doi.org/10.3390/nu175913
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“Circadian Regulation of Vitamin D Target Genes Reveals a Network Shaped by Individual Responsiveness”
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Nutrients 2025, 17(7), 1204; https://doi.org/10.3390/nu1771204
Available online: https://www.mdpi.com/2072-6643/17/7/1204

“Applications of Artificial Intelligence, Machine Learning and Deep Learning in Nutrition: A Systematic Review”
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Nutrients 2024, 16(7), 1073; https://doi.org/10.3390/nu1671073
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Nutrients 2024, 16(13), 2066; https://doi.org/10.3390/nu16132066
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Nutrients 2024, 16(9), 1258; https://doi.org/10.3390/nu1691258
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Nutrients 2024, 16(6), 823; https://doi.org/10.3390/nu166823
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“Ultra-Processed Foods: A Narrative Review of the Impact on the Human Gut Microbiome and Variations in Classification Methods”
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Nutrients 2024, 16(11), 1738; https://doi.org/10.3390/nu16111738
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Nutrients 2024, 16(9), 1278; https://doi.org/10.3390/nu1691278
Available online: https://www.mdpi.com/2072-6643/16/9/1278

“Acute and Repeated Ashwagandha Supplementation Improves Markers of Cognitive Function and Mood”
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Nutrients 2024, 16(12), 1813; https://doi.org/10.3390/nu16121813
Available online: https://www.mdpi.com/2072-6643/16/12/1813

“Functional Foods in Modern Nutrition Science: Mechanisms, Evidence and Public Health Implications”
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Nutrients 2025, 17(13), 2153; https://doi.org/10.3390/nu17132153
Available online: https://www.mdpi.com/2072-6643/17/13/2153

“Impact of Polyphenol-Rich Nutraceuticals on Cognitive Function and Neuroprotective Biomarkers: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial”
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Nutrients 2025, 17(4), 601; https://doi.org/10.3390/nu17040601
Available online: https://www.mdpi.com/2072-6643/17/4/601

“Barriers and Enablers of Healthy Eating Among University Students in Oaxaca de Juarez: A Mixed-Methods Study”
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Nutrients 2025, 17(7), 1263; https://doi.org/10.3390/nu17071263
Available online: https://www.mdpi.com/2072-6643/17/7/1263