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  • Review
  • Open Access
2 Citations
2,592 Views
13 Pages

Integrative Analysis of Rhythmicity: From Biology to Urban Environments and Sustainability

  • Miha Moškon,
  • Tadeja Režen,
  • Matevž Juvančič and
  • Špela Verovšek

From biological to socio-technical systems, rhythmic processes are pervasive in our environment. However, methods for their comprehensive analysis are prevalent only in specific fields that limit the transfer of knowledge across scientific discipline...

  • Review
  • Open Access
29 Citations
8,341 Views
13 Pages

29 June 2022

Unlike the strictly hierarchical organization in the circadian clock system, the gut microbiota rhythmicity has a more complex multilayer network of all taxonomic levels of microbial taxa and their metabolites. However, it is worth noting that the fu...

  • Article
  • Open Access
3 Citations
3,709 Views
26 Pages

Hundreds of LncRNAs Display Circadian Rhythmicity in Zebrafish Larvae

  • Shital Kumar Mishra,
  • Zhaomin Zhong and
  • Han Wang

15 November 2021

Long noncoding RNAs (lncRNAs) have been shown to play crucial roles in various life processes, including circadian rhythms. Although next generation sequencing technologies have facilitated faster profiling of lncRNAs, the resulting datasets require...

  • Article
  • Open Access
18 Citations
8,421 Views
17 Pages

Circadian Rhythmicity of Antioxidant Markers in Rats Exposed to 1.8 GHz Radiofrequency Fields

  • Honglong Cao,
  • Fenju Qin,
  • Xueguan Liu,
  • Jiajun Wang,
  • Yi Cao,
  • Jian Tong and
  • Heming Zhao

Background: The potential health risks of exposure to Radiofrequency Fields (RF) emitted by mobile phones are currently of considerable public interest, such as the adverse effects on the circadian rhythmicities of biological systems. To determine wh...

  • Review
  • Open Access
21 Citations
9,834 Views
18 Pages

The Importance of Rhythmic Stimulation for Preterm Infants in the NICU

  • Joëlle Provasi,
  • Loreline Blanc and
  • Isabelle Carchon

The fetal environment provides the fetus with multiple potential sources of rhythmic stimulation that are not present in the NICU. Maternal breathing, heartbeats, walking, dancing, running, speaking, singing, etc., all bathe the fetus in an environme...

  • Article
  • Open Access
5 Citations
2,399 Views
15 Pages

Altered Rhythmicity, Depressive Ruminative Thinking and Suicidal Ideation as Possible Correlates of an Unrecognized Autism Spectrum in Patients with Borderline Personality Disorder

  • Ivan Mirko Cremone,
  • Liliana Dell’Osso,
  • Benedetta Nardi,
  • Federico Giovannoni,
  • Francesca Parri,
  • Cristiana Pronestì,
  • Chiara Bonelli,
  • Gabriele Massimetti,
  • Stefano Pini and
  • Barbara Carpita

23 December 2024

Background/Objectives: Recent research has explored the presence of subthreshold autistic traits (ATs) in individuals with borderline personality disorder (BPD), suggesting that these traits may contribute to the severity of BPD symptoms and increase...

  • Article
  • Open Access
1,066 Views
30 Pages

Phrase-Oriented Generative Rhythmic Patterns for Jazz Solos

  • Adriano N. Raposo and
  • Vasco N. G. J. Soares

15 October 2025

This study introduces a novel generative approach for crafting phrase-oriented rhythmic patterns in jazz solos, leveraging statistical analyses of a comprehensive corpus, the Weimar Jazz Database. Jazz solos, celebrated for their improvisational comp...

  • Article
  • Open Access
2,836 Views
15 Pages

Formulation of Pruning Maps with Rhythmic Neural Firing

  • Feng-Sheng Tsai,
  • Yi-Li Shih,
  • Chin-Tzong Pang and
  • Sheng-Yi Hsu

17 December 2019

Rhythmic neural firing is thought to underlie the operation of neural function. This triggers the construction of dynamical network models to investigate how the rhythms interact with each other. Recently, an approach concerning neural path pruning h...

  • Article
  • Open Access
2 Citations
3,092 Views
16 Pages

Effect of Short-Term Metro-Rhythmic Stimulations on Gait Variability

  • Katarzyna Nowakowska-Lipiec,
  • Robert Michnik,
  • Sandra Niedzwiedź,
  • Anna Mańka,
  • Patrycja Twardawa,
  • Bruce Turner,
  • Patrycja Romaniszyn-Kania,
  • Aneta Danecka and
  • Andrzej W. Mitas

6 February 2021

The aim of the study was to define the effect of different short-term metro-rhythmic stimulations on the time and spatial parameters of gait. The secondary goal was to test whether prior instructions on how to respond to stimulations played a signifi...

  • Article
  • Open Access
19 Citations
4,038 Views
17 Pages

14 January 2022

Patients with stroke suffer from impaired locomotion, exhibiting unstable walking with increased gait variability. Effects of rhythmic sensory stimulation on unstable gait of patients with chronic stroke are unclear. This study aims to determine the...

  • Article
  • Open Access
20 Citations
9,579 Views
20 Pages

The Effects of an Eight-Week Integrated Functional Core and Plyometric Training Program on Young Rhythmic Gymnasts’ Explosive Strength

  • Cristina Cabrejas,
  • Mónica Solana-Tramunt,
  • Jose Morales,
  • Ainhoa Nieto,
  • Ana Bofill,
  • Eduardo Carballeira and
  • Emanuela Pierantozzi

Background: Explosive strength is essential for rhythmic gymnasts’ performance. It has been suggested that core stability (CS) and plyometric training can enhance athletes’ explosive strength. Nevertheless, there is some uncertainty about...

  • Review
  • Open Access
7 Citations
10,062 Views
30 Pages

The Importance of Physical Fitness Parameters in Rhythmic Gymnastics: A Scoping Review

  • Vasiliki Gaspari,
  • Gregory C. Bogdanis,
  • Ioli Panidi,
  • Andreas Konrad,
  • Gerasimos Terzis,
  • Anastasia Donti and
  • Olyvia Donti

7 September 2024

This scoping review presents an overview of physical fitness parameters in rhythmic gymnastics as well as the association of fitness with gymnasts’ performance, competitive level, and age. PubMed, Scopus, and Sport Discus databases were searche...

  • Article
  • Open Access
1 Citations
1,901 Views
15 Pages

20 April 2023

Overall, this paper provides a comprehensive approach for designing structures subject to rhythmic crowd loading. By considering the randomness of the load model and structural response, the design method provides a more realistic evaluation of the s...

  • Article
  • Open Access
14 Citations
5,513 Views
19 Pages

Motivating Students for Ear-Training with a Rhythmic Dictation Application

  • Matevž Pesek,
  • Lovro Suhadolnik,
  • Peter Šavli and
  • Matija Marolt

27 September 2020

We present the development and evaluation of a gamified rhythmic dictation application for music theory learning. The application was developed as a web application in the existing Troubadour platform for music ear training. The focus of the develope...

  • Article
  • Open Access
10 Citations
3,267 Views
20 Pages

Noncoding RNAs have been known to contribute to a variety of fundamental life processes, such as development, metabolism, and circadian rhythms. However, much remains unrevealed in the huge noncoding RNA datasets, which require further bioinformatic...

  • Article
  • Open Access
13 Citations
4,039 Views
16 Pages

14 December 2020

Authentication has three basic factors—knowledge, ownership, and inherence. Biometrics is considered as the inherence factor and is widely used for authentication due to its conveniences. Biometrics consists of static biometrics (physical chara...

  • Review
  • Open Access
15 Citations
5,564 Views
16 Pages

Rhythmic Physical Activity and Global Cognition in Older Adults with and without Mild Cognitive Impairment: A Systematic Review

  • Gloria Cecilia Vega-Ávila,
  • Diego Fernando Afanador-Restrepo,
  • Yulieth Rivas-Campo,
  • Patricia Alexandra García-Garro,
  • Fidel Hita-Contreras,
  • María del Carmen Carcelén-Fraile,
  • Yolanda Castellote-Caballero and
  • Agustín Aibar-Almazán

Growing evidence suggests that rhythmic physical activity (PA) improves cognitive function in both persons with normal brain aging and with cognitive impairment. This study aims to conduct a systematic review of randomized controlled trials assessing...

  • Article
  • Open Access
5 Citations
3,119 Views
14 Pages

The Effect of Rhythmic Audio-Visual Stimulation on Inhibitory Control: An ERP Study

  • Yifan Wang,
  • Di Wu,
  • Kewei Sun,
  • Yan Zhu,
  • Xianglong Chen and
  • Wei Xiao

Inhibitory control, as an essential cognitive ability, affects the development of higher cognitive functions. Rhythmic perceptual stimulation has been used to improve cognitive abilities. It is unclear, however, whether it can be used to improve inhi...

  • Article
  • Open Access
46 Citations
4,511 Views
17 Pages

Diurnal Rhythmicity of Autophagy Is Impaired in the Diabetic Retina

  • Xiaoping Qi,
  • Sayak K. Mitter,
  • Yuanqing Yan,
  • Julia V Busik,
  • Maria B Grant and
  • Michael E Boulton

7 April 2020

Retinal homeostasis is under both diurnal and circadian regulation. We sought to investigate the diurnal expression of autophagy proteins in normal rodent retina and to determine if this is impaired in diabetic retinopathy. C57BL/6J mice and Bio-Bree...

  • Article
  • Open Access
12 Citations
4,799 Views
9 Pages

Latitudinal Variation in Circadian Rhythmicity in Nasonia vitripennis

  • Silvia Paolucci,
  • Elena Dalla Benetta,
  • Lucia Salis,
  • David Doležel,
  • Louis van de Zande and
  • Leo W. Beukeboom

15 November 2019

Many physiological processes of living organisms show circadian rhythms, governed by an endogenous clock. This clock has a genetic basis and is entrained by external cues, such as light and temperature. Other physiological processes exhibit seasonal...

  • Review
  • Open Access
2 Citations
587 Views
12 Pages

30 December 2025

Background: Rhythmic sensory stimulation, including structured musical interventions, has gained renewed interest as a non-pharmacological strategy that may modulate cortical excitability and network stability in focal epilepsy. Although several smal...

  • Article
  • Open Access
1 Citations
2,553 Views
14 Pages

Rhythmic Analysis in Animal Communication, Speech, and Music: The Normalized Pairwise Variability Index Is a Summary Statistic of Rhythm Ratios

  • Yannick Jadoul,
  • Francesca D’Orazio,
  • Vesta Eleuteri,
  • Jelle van der Werff,
  • Tommaso Tufarelli,
  • Marco Gamba,
  • Teresa Raimondi and
  • Andrea Ravignani

Rhythm is fundamental in many physical and biological systems. Rhythm is relevant to a broad range of phenomena across different fields, including animal bioacoustics, speech sciences, and music cognition. As a result, the interest in developing cons...

  • Article
  • Open Access
4 Citations
9,858 Views
15 Pages

8 November 2022

Pulmonary gas exchanges are vital to human health, and disruptions to this process have been associated with many respiratory diseases. Previous gas exchange studies have predominately relied on whole-body testing and theoretical analysis with 1D or...

  • Article
  • Open Access
17 Citations
6,600 Views
19 Pages

Entrainment of Breast Cell Lines Results in Rhythmic Fluctuations of MicroRNAs

  • Rafael Chacolla-Huaringa,
  • Jorge Moreno-Cuevas,
  • Victor Trevino and
  • Sean-Patrick Scott

Circadian rhythms are essential for temporal (~24 h) regulation of molecular processes in diverse species. Dysregulation of circadian gene expression has been implicated in the pathogenesis of various disorders, including hypertension, diabetes, depr...

  • Article
  • Open Access
16 Citations
3,245 Views
9 Pages

The Association between Maternal Stress and Glucocorticoid Rhythmicity in Human Milk

  • Michelle Romijn,
  • Luca J. L. van Tilburg,
  • Jonneke J. Hollanders,
  • Bibian van der Voorn,
  • Paul de Goede,
  • Koert M. Dolman,
  • Annemieke C. Heijboer,
  • Birit F. P. Broekman,
  • Joost Rotteveel and
  • Martijn J. J. Finken

11 May 2021

Background: Chronic stress is often accompanied by alterations in the diurnal rhythm of hypothalamus–pituitary–adrenal activity. However, there are limited data on the diurnal rhythmicity of breast milk glucocorticoids (GCs) among women with psycholo...

  • Article
  • Open Access
6 Citations
3,049 Views
12 Pages

10 September 2020

A previous study indicated that the swallowing reflex is inhibited during rhythmic jaw movements induced by electrical stimulation of the anterior cortical masticatory area. Rhythmic jaw movements were induced by electrical stimulation of the central...

  • Review
  • Open Access
10 Citations
4,498 Views
15 Pages

The Impact of Rhythmic Physical Activity on Mental Health and Quality of Life in Older Adults with and without Cognitive Impairment: A Systematic Review and Meta-Analysis

  • Marcelina Sánchez-Alcalá,
  • Agustín Aibar-Almazán,
  • Diego Fernando Afanador-Restrepo,
  • María del Carmen Carcelén-Fraile,
  • Alexander Achalandabaso-Ochoa,
  • Yolanda Castellote-Caballero and
  • Fidel Hita-Contreras

14 November 2023

(1) Background: Nowadays, it is essential to implement new non-pharmacological strategies, such as rhythmic physical activity, to improve mental health and quality of life in both individuals experiencing normal brain aging and those with cognitive i...

  • Article
  • Open Access
2,929 Views
12 Pages

The Effects of Rhythm Jump Training on the Rhythmic Reproduction Ability in Jumping and Agility in Elementary School Soccer Players

  • Yudai Kato,
  • Hiroyuki Watanabe,
  • Masashi Kawabata,
  • Noritaka Mamorita,
  • Ryota Muroi,
  • Yukiyasu Tsuda,
  • Yuto Uchida,
  • Yusuke Tsuihiji,
  • Koharu Mogi and
  • Naonobu Takahira
  • + 2 authors

26 January 2025

 Background/Objectives: This study aimed to elucidate the effect of rhythm jump training on the rhythm and motor abilities of elementary school students to provide insights into its potential benefits for their physical performance and coordinat...

  • Article
  • Open Access
1 Citations
2,272 Views
24 Pages

Coupled and Synchronization Models of Rhythmic Arm Movement in Planar Plane

  • Affiani Machmudah,
  • Denys Dutykh and
  • Setyamartana Parman

Nonlinear dynamics have become a new perspective on model human movement variability; however, it is still a debate whether chaotic behavior is indeed possible to present during a rhythmic movement. This paper reports on the nonlinear dynamical behav...

  • Article
  • Open Access
584 Views
13 Pages

Validation of a Rhythmic Jumping Task for the Assessment of Upper–Lower Limb Coordination: Evidence from High-Level Athletes

  • Runjie Li,
  • Hitoshi Koda,
  • Megumi Gonno,
  • Toru Morihara,
  • Tetsuya Miyazaki,
  • Tomoyuki Matsui,
  • Teruo Nomura,
  • Kohei Okado,
  • Chisato Yamamoto and
  • Noriyuki Kida

Background: A rhythmic jumping task that does not require specialized equipment may represent a simple method to assess upper–lower-limb coordination in athletes. Previous studies have been limited to groups with relatively low coordination abi...

  • Article
  • Open Access
649 Views
15 Pages

Sport-Specific Muscle Architectural Adaptations and Jump Performance in Preadolescent Rhythmic Gymnasts

  • Vasiliki Gaspari,
  • Gregory C. Bogdanis,
  • Ioli Panidi,
  • Dimitra A. Kanna,
  • Andreas Salagas,
  • Anastasia Donti,
  • Gerasimos Terzis and
  • Olyvia Donti

28 February 2026

Objective: We examined vastus lateralis (VL), gastrocnemius medialis (GM), gastrocnemius lateralis (GL), and biceps femoris (BF) muscle architecture and force–time parameters recorded during a countermovement jump (CMJ). Methods: Eighty-nine 9...

  • Article
  • Open Access
1 Citations
5,175 Views
10 Pages

Rhythmic synchrony among different individuals has often been observed in various religious rituals and it has been known to bring various psychological effects in human minds. This study investigated the effects of induced rhythmic synchrony with ar...

  • Article
  • Open Access
24 Citations
7,825 Views
15 Pages

The Effect of Eight-Week Functional Core Training on Core Stability in Young Rhythmic Gymnasts: A Randomized Clinical Trial

  • Cristina Cabrejas,
  • Mónica Solana-Tramunt,
  • Jose Morales,
  • Josep Campos-Rius,
  • Alberto Ortegón,
  • Ainhoa Nieto-Guisado and
  • Eduardo Carballeira

It is suggested that core stability (CS) might improve rhythmic gymnasts’ performance. Nevertheless, the effect of core stability training (CST) in CS performance is not clear. Purpose: Evaluating the effect of an eight-week functional CST on y...

  • Article
  • Open Access
11 Citations
3,351 Views
24 Pages

Various types of cells demonstrate ubiquitous rhythmicity registered as simple and complex Ca2+-oscillations, spikes, waves, and triggering phenomena mediated by G-protein and tyrosine kinase coupled receptors. Phospholipase C/IP3-receptors (PLC/IP3R...

  • Review
  • Open Access
3,459 Views
14 Pages

Chikungunya Virus, Metabolism, and Circadian Rhythmicity Interplay in Phagocytic Cells

  • Linamary Alvarez-García,
  • F. Javier Sánchez-García,
  • Mauricio Vázquez-Pichardo and
  • M. Maximina Moreno-Altamirano

11 November 2023

Chikungunya virus (CHIKV) is transmitted to humans by mosquitoes of the genus Aedes, causing the chikungunya fever disease, associated with inflammation and severe articular incapacitating pain. There has been a worldwide reemergence of chikungunya a...

  • Article
  • Open Access
1,345 Views
19 Pages

12 November 2025

Physical inactivity contributes to oxidative stress, hypertension, and progressive kidney dysfunction in individuals with chronic kidney disease (CKD). Rhythmic walking, a low-intensity and easily implemented form of exercise, may offer renal and car...

  • Article
  • Open Access
1 Citations
3,603 Views
19 Pages

Characterization of Mechanical and Cellular Effects of Rhythmic Vertical Vibrations on Adherent Cell Cultures

  • Dongho Kwak,
  • Thomas Combriat,
  • Alexander Refsum Jensenius and
  • Petter Angell Olsen

This paper presents an innovative experimental setup that employs the principles of audio technology to subject adherent cells to rhythmic vertical vibrations. We employ a novel approach that combines three-axis acceleration measurements and particle...

  • Article
  • Open Access
3 Citations
3,159 Views
17 Pages

20 March 2021

Unusual shore-normal and barred-like rhythmic features were found in Camposoto Beach (Bay of Cádiz, SW Spain) during a monitoring program using unmanned aerial systems (UAS). They appeared in the backshore and persisted for 6 months (October 2017–Mar...

  • Article
  • Open Access
34 Citations
4,800 Views
12 Pages

Although there have been increasing reports regarding the effectiveness of dual-task interventions in rehabilitation, the scope of this research is limited to gross motor movement, such as gait among patients with Parkinson’s disease (PD). To expand...

  • Article
  • Open Access
1,371 Views
12 Pages

Functional Verification of the Soybean Pseudo-Response Factor GmPRR7b and Regulation of Its Rhythmic Expression

  • Ziye Song,
  • Jia Liu,
  • Xueyan Qian,
  • Zhengjun Xia,
  • Bo Wang,
  • Nianxi Liu,
  • Zhigang Yi,
  • Zhi Li,
  • Zhimin Dong and
  • Yuqiu Li
  • + 4 authors

The pseudo response regulator (PRR) gene is an important component of the core oscillator involved in plant circadian rhythms and plays an important role in regulating plant growth and development and stress responses. In this study, we investigated...

  • Article
  • Open Access
7 Citations
4,914 Views
14 Pages

Sleep-Related Rhythmic Movement Disorder in Young Children with Down Syndrome: Prevalence and Clinical Features

  • Ceren Kose,
  • Izabelle Wood,
  • Amy Gwyther,
  • Susiksha Basnet,
  • Chloe Gaskell,
  • Paul Gringras,
  • Heather Elphick,
  • Hazel Evans and
  • Catherine M. Hill

6 October 2021

Sleep-related Rhythmic Movement Disorder (RMD) affects around 1% of UK pre-school children. Little is known about RMD in Down syndrome (DS). We aimed to determine: (a) the prevalence of RMD in children with DS aged 1.5–8 years; (b) phenotypic and sle...

  • Article
  • Open Access
1,233 Views
21 Pages

AI-Based Prediction of Visual Performance in Rhythmic Gymnasts Using Eye-Tracking Data and Decision Tree Models

  • Ricardo Bernardez-Vilaboa,
  • F. Javier Povedano-Montero,
  • José Ramon Trillo,
  • Alicia Ruiz-Pomeda,
  • Gema Martínez-Florentín and
  • Juan E. Cedrún-Sánchez

Background/Objective: This study aims to evaluate the predictive performance of three supervised machine learning algorithms—decision tree (DT), support vector machine (SVM), and k-nearest neighbors (KNN) in forecasting key visual skills releva...

  • Article
  • Open Access
1 Citations
1,186 Views
19 Pages

Effects of ZnFe2O4 Nanoparticles on Development and Rhythmic Behavior of Drosophila melanogaster

  • Wenhao Yan,
  • Yunfan Guo,
  • Penghui Li,
  • Ziyan Zhang,
  • Jinjun Yang and
  • Yongyan Sun

14 September 2025

Objectives: This study planned to determine the biological effects associated with ZnFe2O4-NPs exposure using Drosophila melanogaster as an in vivo model. Methods: ZnFe2O4-NPs were hydrothermally synthesized, and the development of offspring flies we...

  • Article
  • Open Access
35 Citations
8,028 Views
11 Pages

31 August 2018

The aim of this study was to investigate the effect of gait training with bilateral rhythmic auditory stimulation (RAS) on lower extremity rehabilitation in stroke patients. Forty-four participants (<6 months after stroke) were randomly allocated...

  • Article
  • Open Access
1,140 Views
19 Pages

Regulation of Synaptic Plasticity and Adaptive Convergence Under Rhythmic Stimulation of an In Vitro Hippocampal Neuronal Network of Cultured Cells

  • Shutong Sun,
  • Longhui Jiang,
  • Yaoyao Liu,
  • Li Shang,
  • Chengji Lu,
  • Shangchen Li,
  • Kui Zhang,
  • Mixia Wang,
  • Xinxia Cai and
  • Jinping Luo

19 January 2026

Synaptic plasticity constitutes a fundamental mechanism of neural systems. Rhythmic activities (e.g., θ and γ oscillations) play a critical role in modulating network plasticity efficiency in biological neural systems. However, the rules...

  • Systematic Review
  • Open Access
3 Citations
9,373 Views
17 Pages

11 December 2024

Background: Cranial Rhythmic Impulse (CRI) or Primary Respiratory Mechanism (PRM), movement felt on the scalp or the rest of the body, respectively, is a fundamental concept used by osteopaths in their practice for their diagnosis and treatment. Howe...

  • Article
  • Open Access
2 Citations
2,453 Views
23 Pages

20 June 2023

The discharge from most karst springs exhibits a consistent and reasonably predictable response to recharge but a few exhibit short-term (‘rhythmic’) changes in flow that are commonly attributed to the geometry of feeder conduits and the...

  • Article
  • Open Access
4 Citations
3,735 Views
12 Pages

How Does the Jumping Performance Differs between Acrobatic and Rhythmic Gymnasts?

  • Isaura Leite,
  • Márcio Goethel,
  • Filipe Conceição and
  • Lurdes Ávila-Carvalho

3 October 2023

An increased jumping performance is key for gymnastics competition routines. Rhythmic gymnasts (RGs) use the jump as one of the main body elements. In Acrobatic Gymnastics (ACRO), top gymnasts must coordinate their jumps with the impulse provided by...

  • Article
  • Open Access
3 Citations
2,030 Views
12 Pages

Physical Education Students’ Opinion on Rhythmic Gymnastics and Its Relation to Gender

  • Alda Reyno-Freundt,
  • Nicolás Meirone-Matus,
  • Mariana Durán Fontecilla and
  • Lilyan Vega-Ramírez

10 January 2025

The gender perspective (GP) aims to generate social change by questioning the stereotypes and roles assigned to individuals and addressing biases and related issues. In Chile, it has been promoted through public policies (Law No.21.369). For this rea...

  • Article
  • Open Access
3,774 Views
22 Pages

Musical Distractions: Music-Based Rhythmic Auditory Stimulation Fails to Improve Gait in Huntington’s Disease

  • Sidney T. Baudendistel,
  • Lauren E. Tueth,
  • Allison M. Haussler and
  • Gammon M. Earhart

Background/Objectives: Huntington’s disease (HD) is a neurodegenerative disorder involving the basal ganglia and is characterized by psychiatric, cognitive, and movement dysfunction, including gait and balance impairment. Given the limited effi...

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