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102 Results Found

  • Review
  • Open Access
14 Citations
4,680 Views
19 Pages

In pharmaceutical research and development, pursuing novel therapeutics and optimizing existing drugs have been revolutionized by the fusion of cutting-edge technologies and computational methodologies. Over the past few decades, the field of drug de...

  • Case Report
  • Open Access
2 Citations
4,544 Views
12 Pages

A Digital Approach for a Complete Rehabilitation with Fixed and Removable Prostheses: A Technical Procedure

  • Etienne Lefrançois,
  • Victor Delanoue,
  • Samuel Morice,
  • Xavier Ravalec and
  • Marie Desclos-Theveniau

25 December 2024

Background: The present article describes a step-by-step maximally digitalized workflow protocol with computer-aided design and computer-aided manufacturing (CAD/CAM) in partial-arch edentulous patients rehabilitated with fixed dental prostheses and...

  • Review
  • Open Access
20 Citations
15,395 Views
64 Pages

Lung cancer is a leading cause of cancer-related deaths worldwide, emphasizing the significance of early detection. Computer-aided diagnostic systems have emerged as valuable tools for aiding radiologists in the analysis of medical images, particular...

  • Article
  • Open Access
11 Citations
3,298 Views
9 Pages

Analysis of Stresses in a Tapered Roller Bearing Using Three-Dimensional Photoelasticity and Stereolithography

  • Filipe Gomes Vieira,
  • Alexandre S. Scari,
  • Pedro Américo Almeida Magalhães Júnior,
  • Jordana S. R. Martins and
  • Cristina Almeida Magalhães

20 October 2019

Digital photoelasticity is an important segment of optical metrology for stress analysis by digital photographic images. Advances in digital image processing, data acquisition, standard recognition and data storage allow the utilization of computer-a...

  • Review
  • Open Access
17 Citations
4,607 Views
35 Pages

Titanium Alloy Implants with Lattice Structures for Mandibular Reconstruction

  • Khaled M. Hijazi,
  • S. Jeffrey Dixon,
  • Jerrold E. Armstrong and
  • Amin S. Rizkalla

27 December 2023

In recent years, the field of mandibular reconstruction has made great strides in terms of hardware innovations and their clinical applications. There has been considerable interest in using computer-aided design, finite element modelling, and additi...

  • Article
  • Open Access
98 Citations
11,231 Views
13 Pages

Early detection of skin cancer through improved techniques and innovative technologies has the greatest potential for significantly reducing both morbidity and mortality associated with this disease. In this paper, an effective framework of a CAD (Co...

  • Review
  • Open Access
125 Citations
12,239 Views
16 Pages

Review on Computer Aided Weld Defect Detection from Radiography Images

  • Wenhui Hou,
  • Dashan Zhang,
  • Ye Wei,
  • Jie Guo and
  • Xiaolong Zhang

10 March 2020

The weld defects inspection from radiography films is critical for assuring the serviceability and safety of weld joints. The various limitations of human interpretation made the development of innovative computer-aided techniques for automatic detec...

  • Article
  • Open Access
4 Citations
1,581 Views
21 Pages

Study Design: This study presents a review of the evolutionary development in reconstructive orbital surgery over the past 3 decades. Additionally, it proposes the Orbital Assessment Algorithm (OA2) to enhance decision-making for intraorbital reconst...

  • Article
  • Open Access
4 Citations
4,198 Views
19 Pages

Knowledge-Driven Manufacturing Process Innovation: A Case Study on Problem Solving in Micro-Turbine Machining

  • Dong Zhang,
  • Gangfeng Wang,
  • Yupeng Xin,
  • Xiaolin Shi,
  • Richard Evans,
  • Biao Guo and
  • Pu Huang

3 November 2021

Micromachining techniques have been applied widely to many industrial sectors, including aerospace, automotive, and precision instruments. However, due to their high-precision machining requirements, and the knowledge-intensive characteristics of min...

  • Article
  • Open Access
35 Citations
4,255 Views
21 Pages

13 December 2021

Computer-aided design has been widely used in structural calculation and analysis, but there are still challenges in generating innovative structures intelligently. Aiming at this issue, a new method was proposed to realize the intelligent generation...

  • Article
  • Open Access
6 Citations
3,009 Views
12 Pages

A Measurement-Aided Control System for Stabilization of the Real-Life Stewart Platform

  • Wojciech P. Hunek,
  • Paweł Majewski,
  • Jarosław Zygarlicki,
  • Łukasz Nagi,
  • Dariusz Zmarzły,
  • Roman Wiench,
  • Paweł Młotek and
  • Piotr Warmuzek

26 September 2022

In the paper, an innovative control system devoted to the stabilization of the parallel manipulator-type Hexapod is presented. The device consists of three main parts, allowing us to reach the desired location during various external disturbances. In...

  • Review
  • Open Access
22 Citations
5,391 Views
26 Pages

State of the Art on Biomaterials for Soft Tissue Augmentation in the Oral Cavity. Part II: Synthetic Polymers-Based Biomaterials

  • Manuel Toledano,
  • Manuel Toledano-Osorio,
  • Álvaro Carrasco-Carmona,
  • Cristina Vallecillo,
  • Raquel Toledano,
  • Antonio Luis Medina-Castillo and
  • Raquel Osorio

17 August 2020

Most of the polymers used as biomaterials for scaffolds are naturally occurring, synthetic biodegradable, and synthetic non-biodegradable polymers. Since synthetic polymers can be adapted for obtaining singular desired characteristics by applying var...

  • Article
  • Open Access
15 Citations
6,228 Views
21 Pages

27 February 2018

Process innovation plays a vital role in the manufacture realization of increasingly complex new products, especially in the context of sustainable development and cleaner production. Knowledge-based innovation design can inspire designers’ creative...

  • Article
  • Open Access
8 Citations
2,971 Views
15 Pages

Multi-Conditional Constraint Generative Adversarial Network-Based MR Imaging from CT Scan Data

  • Mingjie Liu,
  • Wei Zou,
  • Wentao Wang,
  • Cheng-Bin Jin,
  • Junsheng Chen and
  • Changhao Piao

26 May 2022

Magnetic resonance (MR) imaging is an important computer-aided diagnosis technique with rich pathological information. The factor of physical and physiological constraint seriously affects the applicability of that technique. Thus, computed tomograph...

  • Review
  • Open Access
66 Citations
10,680 Views
17 Pages

Review of Deep Learning-Based Atrial Fibrillation Detection Studies

  • Fatma Murat,
  • Ferhat Sadak,
  • Ozal Yildirim,
  • Muhammed Talo,
  • Ender Murat,
  • Murat Karabatak,
  • Yakup Demir,
  • Ru-San Tan and
  • U. Rajendra Acharya

Atrial fibrillation (AF) is a common arrhythmia that can lead to stroke, heart failure, and premature death. Manual screening of AF on electrocardiography (ECG) is time-consuming and prone to errors. To overcome these limitations, computer-aided diag...

  • Article
  • Open Access
2 Citations
1,544 Views
39 Pages

19 April 2025

Addressing the insufficient identification of key consumer requirements in refrigerator design and the current limitations in understanding the impacts and underlying mechanisms of product design on sustainability, this study develops an interdiscipl...

  • Review
  • Open Access
1 Citations
3,835 Views
26 Pages

Exploring Opportunities for Advancements in Lower Limb Socket Fabrication and Testing: A Review

  • Juan Sebastián Salgado Manrique and
  • Christian Cifuentes-De la Portilla

Limb amputation causes significant challenges for patients in achieving effective mobility and functionality through prosthetic limbs. The prosthetic socket plays a pivotal role in the success of rehabilitation. This review explores the current advan...

  • Review
  • Open Access
22 Citations
7,468 Views
35 Pages

17 January 2024

Three-dimensional printing (3DP) technologies are characterized as a set of innovative manufacturing techniques that allow for the creation of complex and/or personalized three-dimensional physical objects on the work surface of a 3D printing machine...

  • Review
  • Open Access
4 Citations
3,983 Views
29 Pages

Biomimetic Tissue Engineering Strategies for Craniofacial Applications

  • Isis Fatima Balderrama,
  • Sogand Schafer,
  • Muhammad El Shatanofy,
  • Edmara T. P. Bergamo,
  • Nicholas A. Mirsky,
  • Vasudev Vivekanand Nayak,
  • Elcio Marcantonio Junior,
  • Adham M. Alifarag,
  • Paulo G. Coelho and
  • Lukasz Witek

Biomimetics is the science of imitating nature’s designs and processes to create innovative solutions for various fields, including dentistry and craniofacial reconstruction. In these areas, biomimetics involves drawing inspiration from living...

  • Article
  • Open Access
4 Citations
2,565 Views
19 Pages

Selective Phenolics Recovery from Aqueous Residues of Pyrolysis Oil through Computationally Designed Green Solvent

  • Amna Qaisar,
  • Lorenzo Bartolucci,
  • Rocco Cancelliere,
  • Nishanth G. Chemmangattuvalappil,
  • Pietro Mele,
  • Laura Micheli and
  • Elisa Paialunga

29 August 2024

Leveraging advanced computational techniques, this study introduces an innovative hybrid computational-experimental approach for the recovery of hydroquinone and p-benzoquinone from the aqueous residue of pyrolysis oil derived from spent coffee groun...

  • Article
  • Open Access
11 Citations
3,368 Views
21 Pages

28 January 2022

A new platform for three-dimensional simulation of Additive Layer Manufacturing (ALM) processes is presented in the paper. The platform is based on homogeneous methods—the Lattice Boltzmann Method (LBM) with elements of Cellular Automata (CA)....

  • Review
  • Open Access
13 Citations
2,948 Views
38 Pages

31 October 2024

The emerging paradigm of personalised bone repair embodies a transformative triad comprising bio-inspired design, digital fabrication, and the exploration of innovative materials. The increasing average age of the population, alongside the rising inc...

  • Protocol
  • Open Access
21 Citations
6,252 Views
10 Pages

Stainless steel crowns are the most popular restoration technique for young permanent first molars treated endodontically. However, these restorations are not aesthetically appealing and need to be replaced. Endocrowns constitute a reliable approach...

  • Article
  • Open Access
2 Citations
5,217 Views
16 Pages

7 September 2024

Our study develops a computer-aided diagnosis (CAD) system for breast ultrasound by presenting an innovative frequency domain technique for extracting mass irregularity features, thereby significantly boosting tumor classification accuracy. The exper...

  • Review
  • Open Access
121 Citations
14,036 Views
31 Pages

Retinal Vessels Segmentation Techniques and Algorithms: A Survey

  • Jasem Almotiri,
  • Khaled Elleithy and
  • Abdelrahman Elleithy

23 January 2018

Retinal vessels identification and localization aim to separate the different retinal vasculature structure tissues, either wide or narrow ones, from the fundus image background and other retinal anatomical structures such as optic disc, macula, and...

  • Article
  • Open Access
2 Citations
3,212 Views
26 Pages

5 August 2024

Shape modeling is a dynamic area in computer graphics with significant applications in computer-aided design, animation, architecture, and entertainment. Virtual sculpting, a key paradigm in free-form modeling, has traditionally been performed on des...

  • Article
  • Open Access
10 Citations
3,687 Views
14 Pages

17 February 2022

In this study, we fabricated a three-dimensional (3D) scaffold using industrial polylactic acid (PLA), which promoted the proliferation and differentiation of human neural stem cells. An industrial PLA 3D scaffold (IPTS) cell chip with a square-shape...

  • Review
  • Open Access
25 Citations
9,954 Views
18 Pages

Artificial Intelligence Advancements in Oncology: A Review of Current Trends and Future Directions

  • Ellen N. Huhulea,
  • Lillian Huang,
  • Shirley Eng,
  • Bushra Sumawi,
  • Audrey Huang,
  • Esewi Aifuwa,
  • Rahim Hirani,
  • Raj K. Tiwari and
  • Mill Etienne

Cancer remains one of the leading causes of mortality worldwide, driving the need for innovative approaches in research and treatment. Artificial intelligence (AI) has emerged as a powerful tool in oncology, with the potential to revolutionize cancer...

  • Article
  • Open Access
5 Citations
5,247 Views
11 Pages

20 November 2021

This study presents an innovative, low-cost, mass-manufacturable ion implantation technique for converting thin film normally on AlGaN/GaN devices into normally off ones. Through TCAD (Technology Computer-Aided Design) simulations, we converted a cal...

  • Article
  • Open Access
19 Citations
3,979 Views
25 Pages

Polyhydroxyalkanoates are biopolyesters whose biocompatibility, biodegradability, environmental sustainability, processing versatility, and mechanical properties make them unique scaffolding polymer candidates for tissue engineering. The development...

  • Article
  • Open Access
11 Citations
4,260 Views
14 Pages

Deep Learning Based Breast Cancer Detection Using Decision Fusion

  • Doğu Manalı,
  • Hasan Demirel and
  • Alaa Eleyan

14 November 2024

Breast cancer, which has the highest mortality and morbidity rates among diseases affecting women, poses a significant threat to their lives and health. Early diagnosis is crucial for effective treatment. Recent advancements in artificial intelligenc...

  • Article
  • Open Access
15 Citations
3,769 Views
17 Pages

HIV and HBV infection are both serious public health challenges. There are more than approximately 4 million patients coinfected with HIV and HBV worldwide, and approximately 5% to 15% of those infected with HIV are coinfected with HBV. Disease progr...

  • Article
  • Open Access
12 Citations
3,129 Views
13 Pages

Model Development for Identifying Aromatic Herbs Using Object Detection Algorithm

  • Samira Nascimento Antunes,
  • Marcelo Tsuguio Okano,
  • Irenilza de Alencar Nääs,
  • William Aparecido Celestino Lopes,
  • Fernanda Pereira Leite Aguiar,
  • Oduvaldo Vendrametto,
  • João Carlos Lopes Fernandes and
  • Marcelo Eloy Fernandes

The rapid evolution of digital technology and the increasing integration of artificial intelligence in agriculture have paved the way for groundbreaking solutions in plant identification. This research pioneers the development and training of a deep...

  • Article
  • Open Access
4 Citations
3,750 Views
26 Pages

Finite Element Modelling of a Parabolic Trough Collector for Concentrated Solar Power

  • Andrea Gilioli,
  • Francesco Cadini,
  • Luca Abbiati,
  • Giulio Angelo Guido Solero,
  • Massimo Fossati,
  • Andrea Manes,
  • Lino Carnelli,
  • Carla Lazzari,
  • Stefano Cardamone and
  • Marco Giglio

3 January 2021

Nowadays the design of large-scale structures can be effectively improved by the adoption of numerical models. Even if experimental tests still play a fundamental role, a methodological approach that combines experimental testing and modelling techni...

  • Article
  • Open Access
3 Citations
2,341 Views
22 Pages

29 December 2022

COVID-19 has led to a severe impact on the society and healthcare system, with early diagnosis and effective treatment becoming critical. The Chest X-ray (CXR) is the most time-saving and cost-effective tool for diagnosing COVID-19. However, manual d...

  • Article
  • Open Access
3 Citations
2,816 Views
17 Pages

16 August 2024

Research on computer-aided arrhythmia classification is actively conducted, but the limited generalization capacity constrains its applicability in practical clinical settings. One of the primary challenges in deploying such techniques in real-world...

  • Review
  • Open Access
8 Citations
9,860 Views
21 Pages

Revolutionizing Sperm Analysis with AI: A Review of Computer-Aided Sperm Analysis Systems

  • Francisco J. Baldán,
  • Diego García-Gil and
  • Carlos Fernandez-Basso

Advances in artificial intelligence (AI) are transforming assisted reproductive technologies by significantly enhancing fertility diagnostics. This review focuses on integrating AI with Computer-Aided Sperm Analysis (CASA) systems to improve assessme...

  • Review
  • Open Access
1 Citations
1,628 Views
22 Pages

2 October 2025

Molecular networking (MN) is a novel mass spectrometry data analysis method that has advanced significantly in recent years and has rapidly emerged as a popular technique. By visualizing the connections between structurally similar compounds in mass...

  • Article
  • Open Access
2,018 Views
24 Pages

Accuracy of Dynamic Computer-Aided Implant Surgery for Biconometric Implant Positioning: A Retrospective Case Series Analysis

  • Luca Comuzzi,
  • Tea Romasco,
  • Massimo Del Fabbro,
  • Margherita Tumedei,
  • Luca Signorini,
  • Francesco Inchingolo,
  • Lorenzo Montesani,
  • Giulia Marchioli,
  • Carlos Fernando Mourão and
  • Natalia Di Pietro
  • + 1 author

Background/Objectives: This retrospective study assessed the accuracy of implant positioning with dynamic computer-aided implant surgery (dCAIS) for Toronto Bridge fabrication, using a conometric prosthetic concept and a new intraoral splinting techn...

  • Review
  • Open Access
2,832 Views
16 Pages

Concept and Design of Cutting Tools for Osseodensification in Implant Dentistry

  • Alexander Isaev,
  • Maria Isaeva,
  • Oleg Yanushevich,
  • Natella Krikheli,
  • Olga Kramar,
  • Aleksandr Tsitsiashvili,
  • Sergey Grigoriev,
  • Catherine Sotova and
  • Pavel Peretyagin

2 December 2024

Osseodensification is an innovative surgical instrumentation technique based on additive (non-cutting) drilling using special burs. It is known from the literature, that the osseodensification burs should operate in a clockwise direction to drill hol...

  • Article
  • Open Access
4 Citations
2,522 Views
18 Pages

ViT-Based Face Diagnosis Images Analysis for Schizophrenia Detection

  • Huilin Liu,
  • Runmin Cao,
  • Songze Li,
  • Yifan Wang,
  • Xiaohan Zhang,
  • Hua Xu,
  • Xirong Sun,
  • Lijuan Wang,
  • Peng Qian and
  • Fufeng Li
  • + 2 authors

29 December 2024

Objectives: Computer-aided schizophrenia (SZ) detection methods mainly depend on electroencephalogram and brain magnetic resonance images, which both capture physical signals from patients’ brains. These inspection techniques take too much time...

  • Article
  • Open Access
52 Citations
3,774 Views
25 Pages

SkinNet-INIO: Multiclass Skin Lesion Localization and Classification Using Fusion-Assisted Deep Neural Networks and Improved Nature-Inspired Optimization Algorithm

  • Muneezah Hussain,
  • Muhammad Attique Khan,
  • Robertas Damaševičius,
  • Areej Alasiry,
  • Mehrez Marzougui,
  • Majed Alhaisoni and
  • Anum Masood

6 September 2023

Background: Using artificial intelligence (AI) with the concept of a deep learning-based automated computer-aided diagnosis (CAD) system has shown improved performance for skin lesion classification. Although deep convolutional neural networks (DCNNs...

  • Review
  • Open Access
5 Citations
8,566 Views
28 Pages

Current Progress in the Development of Resin Materials with Nanofillers for 3D Printing of Denture Base

  • Ahmed Altarazi,
  • Julfikar Haider,
  • Abdulaziz Alhotan,
  • Nikolaos Silikas and
  • Hugh Devlin

16 July 2024

Background: Advanced manufacturing techniques, such as three-dimensional (3D) printing, use digital models from computer-aided design to produce 3D objects. They are frequently employed in different areas of dentistry, such as orthodontics, oral impl...

  • Review
  • Open Access
21 Citations
12,422 Views
17 Pages

Towards Accurate Point-of-Care Tests for Tuberculosis in Children

  • Nina Vaezipour,
  • Nora Fritschi,
  • Noé Brasier,
  • Sabine Bélard,
  • José Domínguez,
  • Marc Tebruegge,
  • Damien Portevin and
  • Nicole Ritz

In childhood tuberculosis (TB), with an estimated 69% of missed cases in children under 5 years of age, the case detection gap is larger than in other age groups, mainly due to its paucibacillary nature and children’s difficulties in delivering...

  • Article
  • Open Access
4 Citations
2,337 Views
29 Pages

Design and Experiment of a Film-Drilling Potato Seeder with Eccentric Coupling

  • Liangqi Pei,
  • Wei Sun,
  • Juanling Wang and
  • Petru A. Simionescu

The new technique of filming in autumn and planting directly through the plastic film in spring is an effective method for water-saving and drought-resistant commercial potato production. However, there are currently no supporting film-drilling seede...

  • Article
  • Open Access
23 Citations
4,082 Views
24 Pages

Colorectal cancer is the third most common and second most lethal tumor globally, causing 900,000 deaths annually. In this research, a computer aided diagnosis system was designed that detects colorectal cancer, using an innovative dataset composing...

  • Article
  • Open Access
3 Citations
1,769 Views
31 Pages

A Hybrid Model of Feature Extraction and Dimensionality Reduction Using ViT, PCA, and Random Forest for Multi-Classification of Brain Cancer

  • Hisham Allahem,
  • Sameh Abd El-Ghany,
  • A. A. Abd El-Aziz,
  • Bader Aldughayfiq,
  • Menwa Alshammeri and
  • Malak Alamri

Background/Objectives: The brain serves as the central command center for the nervous system in the human body and is made up of nerve cells known as neurons. When these nerve cells grow rapidly and abnormally, it can lead to the development of a bra...

  • Article
  • Open Access
15 Citations
2,505 Views
16 Pages

Colon Cancer Disease Diagnosis Based on Convolutional Neural Network and Fishier Mantis Optimizer

  • Amna Ali A. Mohamed,
  • Aybaba Hançerlioğullari,
  • Javad Rahebi,
  • Rezvan Rezaeizadeh and
  • Jose Manuel Lopez-Guede

Colon cancer is a prevalent and potentially fatal disease that demands early and accurate diagnosis for effective treatment. Traditional diagnostic approaches for colon cancer often face limitations in accuracy and efficiency, leading to challenges i...

  • Review
  • Open Access
27 Citations
10,250 Views
25 Pages

Cervical Cancer Detection Techniques: A Chronological Review

  • Wan Azani Mustafa,
  • Shahrina Ismail,
  • Fahirah Syaliza Mokhtar,
  • Hiam Alquran and
  • Yazan Al-Issa

Cervical cancer is known as a major health problem globally, with high mortality as well as incidence rates. Over the years, there have been significant advancements in cervical cancer detection techniques, leading to improved accuracy, sensitivity,...

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