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48 Results Found

  • Article
  • Open Access
2 Citations
2,772 Views
18 Pages

6 June 2023

The castle on Kozlov Rob above Tolmin is one of the most important historical sites in western Slovenia. Over the years, large quantities of finds dating from the late medieval and early modern periods have been recovered from the castle ruins in the...

  • Article
  • Open Access
615 Views
11 Pages

Sex Estimation from Fragmented Thai Femora: Developing Segment-Specific Models Using Discriminant Function Analysis

  • Chanasorn Poodendaen,
  • Narawadee Choompoo,
  • Kaemisa Srisen,
  • Supapit Linlad,
  • Jetniphat Chalermrerm,
  • Worrawit Boonthai,
  • Sitthichai Iamsaard,
  • Nareelak Tangsrisakda,
  • Supatcharee Arun and
  • Suthat Duangchit

Background: Sex estimation from skeletal remains is important for forensic identification, but many methodologies focus on complete elements despite high fragmentation rates in operational contexts. The aim of this study was to develop and validate d...

  • Article
  • Open Access
11 Citations
3,821 Views
15 Pages

Exploring the Functionality of Mesh-to-Mesh Value Comparison in Pair-Matching and Its Application to Fragmentary Remains

  • Zoe McWhirter,
  • Mara A. Karell,
  • Ali Er,
  • Mustafa Bozdag,
  • Oguzhan Ekizoglu and
  • Elena F. Kranioti

9 December 2021

Many cases encountered by forensic anthropologists involve commingled remains or isolated elements. Common methods for analysing these contexts are characterised by limitations such as high degrees of subjectivity, high cost of application, or low pr...

  • Review
  • Open Access
7 Citations
4,666 Views
14 Pages

Systematic Review on Diversity and Distribution of Anopheles Species in Gabon: A Fresh Look at the Potential Malaria Vectors and Perspectives

  • Neil Michel Longo-Pendy,
  • Larson Boundenga,
  • Pyazzi Obame Ondo Kutomy,
  • Clark Mbou-Boutambe,
  • Boris Makanga,
  • Nancy Moukodoum,
  • Judicaël Obame-Nkoghe,
  • Patrice Nzassi Makouloutou,
  • Franck Mounioko and
  • Pierre Kengne
  • + 4 authors

Gabon is located in the malaria hyper-endemic zone, where data concerning malaria vector distribution remains fragmentary, making it difficult to implement an effective vector control strategy. Thus, it becomes crucial and urgent to undertake entomol...

  • Review
  • Open Access
33 Citations
4,991 Views
13 Pages

Cell Wall Proteins Play Critical Roles in Plant Adaptation to Phosphorus Deficiency

  • Weiwei Wu,
  • Shengnan Zhu,
  • Qianqian Chen,
  • Yan Lin,
  • Jiang Tian and
  • Cuiyue Liang

23 October 2019

Phosphorus is one of the mineral nutrient elements essential for plant growth and development. Low phosphate (Pi) availability in soils adversely affects crop production. To cope with low P stress, remodeling of root morphology and architecture is ge...

  • Article
  • Open Access
1 Citations
2,320 Views
8 Pages

The Application of Bony Labyrinth Methods for Forensic Affinity Estimation

  • Alexandra Uhl,
  • Fotios Alexandros Karakostis and
  • Katerina Harvati

21 July 2022

Population affinity identification is important for reconstructing the biological profile of human skeletal remains. Most anthropological methods for predicting population affinity rely on complete crania or cranial parts. However, complete parts are...

  • Review
  • Open Access
19 Citations
6,406 Views
18 Pages

Ovarian cancer represents one of the most challenging gynecologic cancers which still has numerous unknowns on the underlying pathogenesis. In addition to the verified contributors such as genomic predisposition and medical history in the carcinogene...

  • Article
  • Open Access
1,586 Views
27 Pages

15 July 2025

The Laogulou Yashu Archaeological Site in Chongqing represented a significant discovery in the study of medieval Chinese urban heritage. Among its remains, the 13th century terraced building F1 stood out for its scale and function as a governmental q...

  • Review
  • Open Access
68 Citations
12,763 Views
41 Pages

Genetic and Non-Genetic Mechanisms Underlying Cancer Evolution

  • Yelyzaveta Shlyakhtina,
  • Katherine L. Moran and
  • Maximiliano M. Portal

18 March 2021

Cancer development can be defined as a process of cellular and tissular microevolution ultimately leading to malignancy. Strikingly, though this concept has prevailed in the field for more than a century, the precise mechanisms underlying evolutionar...

  • Review
  • Open Access
178 Citations
14,146 Views
15 Pages

Metabolic Responses of Bacterial Cells to Immobilization

  • Joanna Żur,
  • Danuta Wojcieszyńska and
  • Urszula Guzik

In recent years immobilized cells have commonly been used for various biotechnological applications, e.g., antibiotic production, soil bioremediation, biodegradation and biotransformation of xenobiotics in wastewater treatment plants. Although the li...

  • Review
  • Open Access
1 Citations
1,658 Views
15 Pages

Haemosporidian parasites (Apicomplexa, Haemosporida) are diverse obligatory heteroxenous protists, which infect all major groups of terrestrial vertebrates and use dipterous blood-sucking insects as vectors. These pathogens are responsible for variou...

  • Study Protocol
  • Open Access
3 Citations
7,609 Views
10 Pages

Measuring Interprofessional Collaboration’s Impact on Healthcare Services Using the Quadruple Aim Framework: A Protocol Paper

  • Yang Yann Foo,
  • Xiaohui Xin,
  • Jai Rao,
  • Nigel C. K. Tan,
  • Qianhui Cheng,
  • Elaine Lum,
  • Hwee Kuan Ong,
  • Sok Mui Lim,
  • Kirsty J. Freeman and
  • Kevin Tan

Despite decades of research on the impact of interprofessional collaboration (IPC), we still lack definitive proof that team-based care can lead to a tangible effect on healthcare outcomes. Without return on investment (ROI) evidence, healthcare lead...

  • Article
  • Open Access
28 Citations
11,323 Views
62 Pages

18 March 2020

Several aspects of the fascinating evolutionary history of toothed and baleen whales (Cetacea) are still to be clarified due to the fragmentation and discontinuity (in space and time) of the fossil record. Here we open a window on the past, describin...

  • Review
  • Open Access
11 Citations
4,254 Views
20 Pages

30 April 2022

Despite therapeutical advancements, and in contrast to other malignancies, esophageal adenocarcinoma (EAC) prognosis remains dismal while the incidence has markedly increased worldwide over the past decades. EAC is a malignancy of the distal esophage...

  • Article
  • Open Access
1,520 Views
26 Pages

Taxonomic Notes on Lerniana Delicado et Hauffe, 2022, Trichonia Schütt, 1980 (Truncatelloidea: Hydrobiidae: Horatiinae) and Allied Taxa

  • Aleksandra Jaszczyńska,
  • Jozef Grego,
  • Sebastian Hofman,
  • Artur Osikowski and
  • Andrzej Falniowski

26 August 2025

The genera: Lerniana Delicado et Hauffe, 2022, Trichonia Schütt, 1980, and two clades (“Radomaniolaelongata Radoman, 1973, and an unnamed clade referred to as “Radomaniola” sp. 1, sp. 2) whose assignment to any genus re...

  • Article
  • Open Access
1 Citations
3,772 Views
14 Pages

The Fox from Bajiazui (Qingyang, Central China) and an Update on Early Pleistocene Foxes from China

  • Saverio Bartolini-Lucenti,
  • Qigao Jiangzuo,
  • Hao Jiang,
  • Zhaoyu Li,
  • Kun Xie and
  • Joan Madurell-Malapeira

20 November 2023

(1) Background: despite the fact that nowadays the genus Vulpes Frisch, 1775, is the most diverse among extant Canidae, its fossil record is utterly scarce, especially in the Asian Pliocene. The sparse nature of this record further complicates the re...

  • Article
  • Open Access
5 Citations
3,764 Views
13 Pages

Prevalence and Clinical Characteristics of Hearing Loss Caused by MYH14 Variants

  • Ken Hiramatsu,
  • Shin-ya Nishio,
  • Shin-ichiro Kitajiri,
  • Tomohiro Kitano,
  • Hideaki Moteki,
  • Shin-ichi Usami and
  • on behalf of the Deafness Gene Study Consortium

15 October 2021

Variants in MYH14 are reported to cause autosomal dominant nonsyndromic hereditary hearing loss (ADNSHL), with 34 variants reported to cause hearing loss in various ethnic groups. However, the available information on prevalence, as well as with rega...

  • Article
  • Open Access
22 Citations
4,753 Views
14 Pages

Characterization of Differences in the Composition and Content of Volatile Compounds in Cucumber Fruit

  • Jie Zhang,
  • Xiuchao Gu,
  • Wenjing Yan,
  • Lina Lou,
  • Xuewen Xu and
  • Xuehao Chen

12 April 2022

The cucumber is characterized by the presence of a wide range of volatile organic compounds (VOCs), which are recognized as the main responsible for its unique flavor. However, research on the types and contents of VOCs in different cucumber cultivar...

  • Article
  • Open Access
2 Citations
1,990 Views
18 Pages

Short Standing and Propagating Internal Waves in an Ice-Covered Shallow Lake

  • Sergey Bogdanov,
  • Roman Zdorovennov,
  • Nikolai Palshin,
  • Tatiana Efremova and
  • Galina Zdorovennova

19 July 2023

The intensity of vertical heat and mass transfer remains among the challenging topics in the study of ice-covered lakes. Presumably, internal waves (IWs) make a significant contribution to the heat transfer in the water column. However, the mechanism...

  • Review
  • Open Access
53 Citations
10,061 Views
11 Pages

Pathogenomics of Endometriosis Development

  • Vladislav Baranov,
  • Olga Malysheva and
  • Maria Yarmolinskaya

For over 100 years, endometriosis, as a chronic, estrogen-dependent, inflammatory, heritable disease affecting approximately 5–10% of women in reproductive age has been the focus of clinicians and scientists. In spite of numerous environmental,...

  • Article
  • Open Access
12 Citations
4,966 Views
19 Pages

Focus on the Role of Klotho Protein in Neuro-Immune Interactions in HT-22 Cells Upon LPS Stimulation

  • Kinga Rusinek,
  • Przemysław Sołek,
  • Anna Tabęcka-Łonczyńska,
  • Marek Koziorowski and
  • Jennifer Mytych

16 May 2020

Neuroinflammation is defined as the activation of the brain’s innate immune system in response to an inflammatory challenge and is considered to be a prominent feature of neurodegenerative diseases. The contribution of overactivated neuroglial...

  • Article
  • Open Access
6 Citations
7,735 Views
27 Pages

Exploring New Ways to Reconstruct the Forma Urbis Romae: An Archaeometric Approach (CL Color and Stable Isotope Analyses)

  • Lluís Casas,
  • Roberta Di Febo,
  • Mauro Brilli,
  • Francesca Giustini,
  • Marco Gozzi,
  • Francesca De Caprariis,
  • Juan Diego Martín-Martín and
  • Claudio Parisi Presicce

11 December 2021

The Forma Urbis Romae (F.U.) was a 3rd-century-AD monumental map of ancient Rome consisting of 151 rectangular marble slabs. Several efforts have been made to reconstruct it from its current incomplete and fragmentary condition. In this paper, we exp...

  • Article
  • Open Access
3 Citations
6,535 Views
21 Pages

New Lizard Specimens from the Campanian Wapiti Formation of Alberta, Canada

  • Samantha M. Hamilton,
  • Ilaria Paparella,
  • Phil R. Bell,
  • Nicolás E. Campione,
  • Federico Fanti,
  • Derek W. Larson,
  • Robin L. Sissons,
  • Matthew J. Vavrek,
  • Michael J. Balsai and
  • Corwin Sullivan

3 November 2023

Reported lizard material from the Wapiti Formation (central-western Alberta, Canada) is limited to fragmentary remains of Kleskunsaurus grandeprairiensis and Socognathus unicuspis, a partial dentary attributed to Chamops cf. C. segnis, and a vertebra...

  • Review
  • Open Access
18 Citations
6,497 Views
35 Pages

In recent years, the evaluation of many plant-derived compounds as potential new drugs or functional foods has become an active research topic. The morphological characteristics of quinces of the genera Cydonia sp., Chaenomeles sp., and Pseuocydonia...

  • Article
  • Open Access
438 Views
19 Pages

12 December 2025

Coordinate measuring techniques are essential for determining the diameter and roundness of circular features, yet measurements based on short arc segments remain highly sensitive to form deviations, sampling strategy, and instrument error. With the...

  • Article
  • Open Access
1,493 Views
21 Pages

30 October 2025

The Song 宋, Yuan 元, and Ming 明 dynasties (960–1644) witnessed the flourishing development of the Chinese Buddhist Canon (CBC), with about fifteen editions of the CBC constructed in this period. This was also an important pe...

  • Article
  • Open Access
2 Citations
1,570 Views
15 Pages

The Stylo Cysteine-Rich Peptide SgSnakin1 Is Involved in Aluminum Tolerance through Enhancing Reactive Oxygen Species Scavenging

  • Xueqiong Guo,
  • Shengnan Zhu,
  • Yingbin Xue,
  • Yan Lin,
  • Jingying Mao,
  • Shuyue Li,
  • Cuiyue Liang,
  • Xing Lu and
  • Jiang Tian

Stylo (Stylosanthes spp.) is an important pasture legume with strong aluminum (Al) resistance. However, the molecular mechanisms underlying its Al tolerance remain fragmentary. Due to the incomplete genome sequence information of stylo, we first cond...

  • Article
  • Open Access
2,190 Views
24 Pages

7 February 2025

The restoration of medieval wall paintings often involves the combination of heterogeneous techniques and materials considering their nature and period. One of the many obstacles in the study of the restoration of these types of artifacts is the pauc...

  • Article
  • Open Access
2 Citations
943 Views
14 Pages

Lignification of juice sacs is a primary contributor to reductions in fruit quality, with impacts on taste and economic value of pomelo (Citrus grandis). To date, information on the regulation of fruit lignification remains fragmentary. In this study...

  • Article
  • Open Access
6 Citations
5,305 Views
20 Pages

Karyotypic Evolution of Sauropsid Vertebrates Illuminated by Optical and Physical Mapping of the Painted Turtle and Slider Turtle Genomes

  • Ling Sze Lee,
  • Beatriz M. Navarro-Domínguez,
  • Zhiqiang Wu,
  • Eugenia E. Montiel,
  • Daleen Badenhorst,
  • Basanta Bista,
  • Thea B. Gessler and
  • Nicole Valenzuela

12 August 2020

Recent sequencing and software enhancements have advanced our understanding of the evolution of genomic structure and function, especially addressing novel evolutionary biology questions. Yet fragmentary turtle genome assemblies remain a challenge to...

  • Article
  • Open Access
1 Citations
2,191 Views
19 Pages

27 August 2022

The increasing number of HIV-infected people who are receiving ART, including those with low adherence, is causing the spread of HIV drug resistance (DR). A total of 1396 plasma samples obtained from treatment-experienced patients from the Volga fede...

  • Article
  • Open Access
593 Views
21 Pages

1 October 2025

The Lower Cretaceous Jiufotang Formation in the Fuxin Basin contains a proven petroleum system. However, its southern part remains underexplored due to limited drilling and fragmentary sedimentary studies. To address this issue, we conducted detailed...

  • Interesting Images
  • Open Access
391 Views
7 Pages

Expanding Insular Presence of the Giant Water Bug Lethocerus patruelis (Stål, 1854) Across the Aegean Islands: New Evidence of an Emerging Archipelagic Distribution

  • Giorgos Stavrianakis,
  • Linne Sykora,
  • Edwin van der Veldt,
  • Alexandros D. Kouris,
  • Apostolos Christopoulos and
  • Yiannis G. Zevgolis

7 January 2026

Lethocerus patruelis (Stål, 1854), the sole European belostomatid, is an apex invertebrate predator in Mediterranean freshwater systems and a species known for its strong flight capacity and growing range expansion record. While its continental...

  • Article
  • Open Access
909 Views
34 Pages

The Orchidaceae family in Calabria has been scarcely investigated during the 21st century, and available knowledge remains fragmentary, particularly for the rarer taxa. The last comprehensive study dates back to 2002, whereas subsequent checklists, l...

  • Review
  • Open Access
13 Citations
4,510 Views
43 Pages

16 October 2023

Liver diseases, characterized by high morbidity and mortality, represent a substantial medical problem globally. The current therapeutic approaches are mainly aimed at reducing symptoms and slowing down the progression of the diseases. Organ transpla...

  • Review
  • Open Access
269 Views
11 Pages

Autopsy-Proven Snakebite Envenoming Deaths: A Review of Forensic and Pathological Evidence

  • Matteo Antonio Sacco,
  • Saverio Gualtieri,
  • Aurora Princi and
  • Isabella Aquila

Background/Objectives: Snakebite envenoming remains a critical yet frequently under-recognized cause of mortality in many parts of the world, particularly in tropical and rural areas where access to timely medical care and accurate post-mortem invest...

  • Article
  • Open Access
2,746 Views
30 Pages

Forecasting Channel Morphodynamics in the Ulken Almaty River (Ile Alatau, Kazakhstan)

  • Ainur Mussina,
  • Marzhan Tursyngali,
  • Kassym Duskayev,
  • Javier Rodrigo-Ilarri,
  • María-Elena Rodrigo-Clavero and
  • Assel Abdullayeva

6 July 2025

This article focuses on forecasting morphological changes in small rivers, using the Ulken Almaty River, located on the northern slope of the Ile Alatau range in the Tien Shan mountain system, as a case study. One of the key components of river morph...

  • Feature Paper
  • Article
  • Open Access
1 Citations
5,057 Views
22 Pages

13 September 2024

Uruguayan ammonoids are preserved in phosphate and siderite nodules found at the basalmost tillite-like conglomerates of the San Gregorio Formation. This lithostratigraphic unit was deposited under glacial conditions and its age (as well as that of t...

  • Article
  • Open Access
1,162 Views
16 Pages

Age Estimation Through Osteon Histomorphometry: Analysis of Femoral Cross-Sections from Historical Autopsy Samples

  • Raffaella Minella,
  • Giada Sciâdi Steiger,
  • Aldo Di Fazio,
  • Francesco Introna and
  • Enrica Macorano

Background/Objectives: Age estimation is of fundamental importance in forensic investigations. When traditional methods based on gross bone morphology or morphometric analysis cannot be applied, forensic experts must rely on multidisciplinary approac...

  • Article
  • Open Access
1 Citations
3,744 Views
17 Pages

Information System for Selection of Conditions and Equipment for Mammalian Cell Cultivation

  • Natalia Menshutina,
  • Elena Guseva,
  • Diana Batyrgazieva and
  • Igor Mitrofanov

25 February 2021

Over the past few decades, animal cell culture technology has advanced significantly. It is now considered a reliable, functional, and relatively well-developed technology. At present, biotherapeutic drugs are synthesized using cell culture technique...

  • Article
  • Open Access
7 Citations
4,114 Views
22 Pages

6 July 2022

The alpine treeline ecotones are an early indicator of vegetation’s response to changes in climate, and the advancement of diffuse treeline ecotones has been associated with mean annual warming temperatures. However, the knowledge of how tree d...

  • Perspective
  • Open Access
7 Citations
3,553 Views
25 Pages

Position Paper Introducing a Sustainable, Universal Approach to Retrofitting Residential Buildings

  • Małgorzata Fedorczak-Cisak,
  • Mark Bomberg,
  • David W. Yarbrough,
  • Lowell E. Lingo and
  • Anna Romanska-Zapala

Protests during the 2021 Climate Conference in Glasgow exemplified our dilemma. The establishment perpetuates old thinking, while young people demand a new approach to mitigate the impact of climate change. The authors agree with the young people, an...

  • Article
  • Open Access
7 Citations
5,184 Views
18 Pages

Molecular Effects of Auto-Antibodies on Angiotensin II Type 1 Receptor Signaling and Cell Proliferation

  • Aurélie Philippe,
  • Gunnar Kleinau,
  • Jason Jannis Gruner,
  • Sumin Wu,
  • Daniel Postpieszala,
  • David Speck,
  • Harald Heidecke,
  • Simon J. Dowell,
  • Gabriela Riemekasten and
  • Patrick Scheerer
  • + 5 authors

The angiotensin II (Ang II) type 1 receptor (AT1R) is involved in the regulation of blood pressure (through vasoconstriction) and water and ion homeostasis (mediated by interaction with the endogenous agonist). AT1R can also be activated by auto-anti...

  • Article
  • Open Access
14 Citations
9,054 Views
21 Pages

23 June 2023

The textile and fashion industry is the second industry (after aviation) that pollutes the planet the most, and it uses natural and human resources excessively and irresponsibly. Fast fashion harms the environment. Fast fashion stands for low quality...

  • Article
  • Open Access
357 Views
11 Pages

The Role of Preoperative Antibiotics in Osteosynthesis of the Hand and Wrist: A Retrospective Analysis

  • Anja Hunziker,
  • Ilja Kaech,
  • Brigitta Gahl,
  • Konrad Mende,
  • Dirk J. Schaefer and
  • Alexandre Kaempfen

15 December 2025

Background: Preventing postoperative infections in hand surgery is an important factor for achieving sustainable results of surgical procedures. To prevent infections, especially when implants are used, preoperative prophylactic antibiotics are appli...

  • Article
  • Open Access
36 Citations
4,928 Views
21 Pages

8 February 2019

The issue of monitoring surface motions in post-mining areas in Europe is important due to the fact that a significant number of post-mining areas lie in highly-urbanized and densely-populated regions. Examples can be found in: Belgium, the Czech Rep...

  • Review
  • Open Access
4 Citations
2,658 Views
19 Pages

Long Intergenic Non-Coding RNAs of Human Chromosome 18: Focus on Cancers

  • Pavel V. Ershov,
  • Evgeniy O. Yablokov,
  • Yuri V. Mezentsev and
  • Alexis S. Ivanov

Malignant neoplasms are characterized by high molecular heterogeneity due to multilevel deregulation of gene expression and cellular functions. It is known that non-coding RNAs, including long intergenic non-coding RNAs (lincRNAs), can play significa...