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31,134 Results Found

  • Review
  • Open Access
130 Citations
5,238 Views
26 Pages

Exercise for People with Cancer: A Systematic Review

  • R. Segal,
  • C. Zwaal,
  • E. Green,
  • J.R. Tomasone and ,
  • A. Loblaw,
  • T. Petrella and
  • the Exercise for People with Cancer Guideline Development Group
  • + 2 authors+ 0 author

1 August 2017

Background: This systematic review was completed by the Exercise for People with Cancer Guideline Development Group, a group organized by Cancer Care Ontario’s Program in Evidence-Based Care (PEBC). It provides background and guidance for clinicians...

  • Article
  • Open Access
251 Citations
7,511 Views
7 Pages

Exercise for People with Cancer: A Clinical Practice Guideline

  • R. Segal,
  • C. Zwaal,
  • E. Green,
  • J.R. Tomasone and ,
  • A. Loblaw,
  • T. Petrella and
  • the Exercise for People with Cancer Guideline Development Group
  • + 2 authors+ 0 author

1 February 2017

Background: Development of this guideline was undertaken by the Exercise for People with Cancer Guideline Development Group, a group organized by Cancer Care Ontario’s Program in Evidence-Based Care (pebc). The purpose of the guideline was to provide...

  • Review
  • Open Access
  • Best Paper Award
45 Citations
17,082 Views
21 Pages

31 January 2018

There is ample evidence that regular moderate to vigorous aerobic physical activity is related to a reduced risk for various forms of cancer to suggest a causal relationship. Exercise is associated with positive changes in fitness, body composition,...

(This article belongs to the Special Issue Exercise and Chronic Disease)
  • Article
  • Open Access
6 Citations
3,636 Views
8 Pages

Functional Translation of Exercise Responses from Exercise Testing to Exercise Training: The Test of a Model

  • Tristan Tyrrell,
  • Jessica Pavlock,
  • Susan Bramwell,
  • Cristina Cortis and ,
  • Scott T. Doberstein,
  • Andrea Fusco,
  • John P. Porcari and
  • Carl Foster
  • + 3 authors+ 0 author

Exercise prescription based on exercise test results is complicated by the need to downregulate the absolute training intensity to account for cardiovascular drift in order to achieve a desired internal training load. We tested a recently developed g...

(This article belongs to the Special Issue Exercise Evaluation and Prescription—2nd Edition)
  • Article
  • Open Access
7 Citations
73,032 Views
11 Pages

29 September 2021

This study aimed to compare the physiologic effects of regular water consumption to those of electrolyte drink consumption in exercise capacity and recovery after exhaustive exercise. The participants were 10 healthy young men who exercised on a trea...

  • Review
  • Open Access
58 Citations
11,566 Views
15 Pages

15 April 2020

A large number of studies have described a positive relationship between physical exercise and cognition. Physical exercise can be divided into closed-skill exercise (CSE) and open-skill exercise (OSE) based on the predictability of the performance e...

(This article belongs to the Special Issue Human Skeletal Muscle and Tendon Characteristics in Sport and Rehabilitation)
  • Article
  • Open Access
4 Citations
6,433 Views
11 Pages

Resistance exercise with devices offering mechanisms to isolate the lumbar spine is effective to improve muscle strength and clinical outcomes. However, previously assessed devices with these mechanisms are not conducive for home exercise programs. T...

(This article belongs to the Special Issue Exercise Evaluation and Prescription—2nd Edition)
  • Article
  • Open Access
76 Citations
8,308 Views
12 Pages

This study was intended to determine the applicability of an augmented-reality-based muscle reduction prevention exercise program for elderly Korean women by observing changes in exercise self-efficacy and verifying the effectiveness of the program i...

(This article belongs to the Special Issue Rehabilitation and Healthcare Systems that Work)
  • Article
  • Open Access
27 Citations
7,033 Views
11 Pages

We aimed to investigate the effect of different intensities of aerobic exercise (VO2max: 50% vs. 80%) on body weight, body fat percentage, lipid profiles, and adipokines in obese middle-aged women after 8 weeks of combined aerobic and resistance exer...

(This article belongs to the Special Issue Exercise for Health)
  • Review
  • Open Access
122 Citations
11,300 Views
21 Pages

The Role of SIRT3 in Exercise and Aging

  • Lei Zhou,
  • Ricardo Pinho,
  • Yaodong Gu and
  • Zsolt Radak

20 August 2022

The health benefits of regular exercise are well established. Nonetheless, the molecular mechanism(s) responsible for exercise-induced health benefits remain a topic of debate. One of the key cell-signaling candidates proposed to provide exercise-ind...

(This article belongs to the Topic Skeletal Muscle Structure and Function in Health and Disease)
  • Review
  • Open Access
35 Citations
11,840 Views
14 Pages

Exercise as a Therapeutic Intervention in Gestational Diabetes Mellitus

  • Konstantina Dipla,
  • Andreas Zafeiridis,
  • Gesthimani Mintziori,
  • Afroditi K. Boutou and ,
  • Dimitrios G. Goulis and
  • Anthony C. Hackney
  • + 1 author+ 0 author

26 March 2021

Gestational Diabetes Mellitus (GDM) is defined as any degree of glucose intolerance with onset or first recognition during pregnancy. Regular exercise is important for a healthy pregnancy and can lower the risk of developing GDM. For women with GDM,...

(This article belongs to the Special Issue Exercise Endocrinology)
  • Review
  • Open Access
518 Views
6 Pages

Peripheral arterial disease (PAD) is a chronic, progressive atherosclerotic process limiting the blood flow to the lower limbs which causes an imbalance between oxygen supply and metabolic needs during physical activity with typical claudication symp...

  • Review
  • Open Access
43 Citations
26,053 Views
29 Pages

Effects of Different Types of Exercise on Kidney Diseases

  • Hamid Arazi,
  • Majid Mohabbat,
  • Payam Saidie,
  • Akram Falahati and
  • Katsuhiko Suzuki

10 March 2022

The effects of exercise on kidney function have been studied for more than three decades. One of the most common health issues among patients with chronic kidney disease (CKD) is a lack of physical activity, which leads to a low exercise capacity in...

  • Review
  • Open Access
55 Citations
48,067 Views
32 Pages

Nutritional Compounds to Improve Post-Exercise Recovery

  • Emma O’Connor,
  • Toby Mündel and
  • Matthew J. Barnes

29 November 2022

The metabolic and mechanical stresses associated with muscle-fatiguing exercise result in perturbations to bodily tissues that lead to exercise-induced muscle damage (EIMD), a state of fatigue involving oxidative stress and inflammation that is accom...

(This article belongs to the Special Issue Nutrition-Based Strategies to Reduce Exercise-Induced Muscle Damage and Soreness)
  • Article
  • Open Access
3 Citations

The effect of a short-term ketogenic diet on exercise efficiency during graded exercise in healthy adults

  • Wonhee Cho,
  • Hwaebong Jung,
  • Sunghyun Hong,
  • Hyuk In Yang and ,
  • Dong-Hyuk Park,
  • Sang-Hoon Suh,
  • Dong Hoon Lee,
  • Yong-Sahm Choe,
  • Joon Young Kim and
  • Justin Y. Jeon
  • + 6 authors+ 1 author

Objective: We examined the effects of short-term KD on exercise efficiency and hormonal response during and after the graded exercise testing. Methods: Fourteen untrained healthy adults (8 males, 6 females, age 26.4 ± 3.1 [SD] years; BMI 24.8 ± 4.6 k...

  • Article
  • Open Access
2 Citations
2,764 Views
12 Pages

The purpose of this study was to analyze and understand the mechanisms of physical activity obstructions in hospitalized cancer patients by investigating their physical activity levels, previous exercise experience levels, and exercise recognition. A...

(This article belongs to the Section Global Health)
  • Review
  • Open Access
59 Citations
16,113 Views
15 Pages

30 October 2023

Accelerated biological vascular ageing is still a major driver of the increasing burden of cardiovascular disease and mortality. Exercise training delays this process, known as early vascular ageing, but often lacks effectiveness due to a lack of und...

(This article belongs to the Collection Molecular Mechanisms of Exercise and Healthspan)
  • Review
  • Open Access
46 Citations
16,485 Views
19 Pages

10 August 2020

As exercise intensity exceeds 65% of maximal oxygen uptake carbohydrate energy sources predominate. However, relative to the meager 4–5 g blood glucose pool size in a postabsorptive individual (0.9–1.0 g·L−1 × 5 L blood...

(This article belongs to the Special Issue Progress in Glucose Metabolism)
  • Article
  • Open Access
9 Citations
4,757 Views
19 Pages

Effects of Acute Exercise and Learning Strategy Implementation on Memory Function

  • Paul D. Loprinzi,
  • Faith Harris,
  • Kyle McRaney,
  • Morgan Chism and ,
  • Raymond Deming,
  • Timothy Jones,
  • Liye Zou and
  • Miaoqing Tan
  • + 3 authors+ 0 author

5 September 2019

Background and Objectives: Long-term potentiation (LTP), the functional connectivity among neurons, is considered a mechanism of episodic memory. Both acute exercise and learning are thought to influence memory via an LTP-related mechanism. Limited r...

  • Review
  • Open Access
20 Citations
7,806 Views
15 Pages

Mitigating Sarcopenia with Diet and Exercise

  • Alex Shefflette,
  • Neel Patel and
  • John Caruso

Sarcopenia is the loss of muscle mass and function from aging, inactivity, or disuse. It is a comorbidity to numerous conditions that exacerbates their severity and adversely impacts activities of daily living. While sarcopenia now receives more atte...

(This article belongs to the Section Exercise and Health)
  • Article
  • Open Access
2 Citations
1,839 Views
10 Pages

Physical exercise programs are useful and necessary for the treatment of schizophrenia. The aim of this study was to assess the experiences of participants with schizophrenia in an out-of-hospital exercise program designed and supervised by qualified...

(This article belongs to the Special Issue Physical Education, Physical Activity and Human Health)
  • Review
  • Open Access
4 Citations
8,623 Views
10 Pages

Physical inactivity is a major risk factor for public health. Due to the decline in physical demands of daily living exercise becomes an increasingly important contributor to an active lifestyle. The evidence on health benefits of exercise, particula...

(This article belongs to the Special Issue Tailored Exercise in Patients with Chronic Diseases)
  • Article
  • Open Access
26 Citations
12,649 Views
13 Pages

6 January 2015

The aim of this study was to evaluate the effects of skimmed milk as a recovery drink following moderate–vigorous cycling exercise on subsequent appetite and energy intake in healthy, female recreational exercisers. Utilising a randomised cross-over...

(This article belongs to the Special Issue Energy Balance)
  • Review
  • Open Access
23 Citations
8,474 Views
23 Pages

Diabetic nephropathy (DN) is a serious complication of diabetes, and its progression is influenced by factors like oxidative stress, inflammation, cell death, and fibrosis. Compared to drug treatment, exercise offers a cost-effective and low-risk app...

(This article belongs to the Section Molecular Biology)
  • Article
  • Open Access
405 Views
20 Pages

Energy Substrate Utilization and Body Composition Following Exercise Preconditioning During Alternate-Day Fasting and Concurrent Exercise in Mice

  • Jungyong Lee,
  • Taeho Kim,
  • Deunsol Hwang,
  • Sunghwan Kyun and ,
  • Inkwon Jang,
  • Nayeon Kim,
  • Kiwon Lim,
  • Hun-Young Park,
  • Insu Kwon and
  • Jisu Kim
  • + 6 authors+ 1 author

27 August 2026

Background/Objectives: Alternate-day fasting (ADF) combined with exercise has been suggested as an effective lifestyle strategy for reducing fat mass while preserving lean mass. However, whether exercise preconditioning before ADF plus concurrent exe...

(This article belongs to the Special Issue Metabolic Adaptations to Exercise: Mechanisms, Modulators, and Health Impacts)
  • Review
  • Open Access
37 Citations
33,696 Views
17 Pages

Premenstrual Syndrome and Exercise: A Narrative Review

  • Barbara N. Sanchez,
  • William J. Kraemer and
  • Carl M. Maresh

20 June 2023

Premenstrual Syndrome (PMS) is a complex physiological and psychological condition that affects a significant number of women during their reproductive years. Although the exact etiology of PMS remains unclear, its symptoms, including mood swings, bl...

  • Article
  • Open Access
1,979 Views
22 Pages

The Effect of Muscle Blood Flow Restriction During Dynamic Exercise on Carotid Baroreflex Sensitivity

  • Evgenia D. Cherouveim,
  • Panagiotis G. Miliotis,
  • Anastasios Makris,
  • Maria D. Koskolou and ,
  • Konstantina Dipla,
  • Ioannis S. Vrabas and
  • Nickos D. Geladas
  • + 2 authors+ 0 author

Background/Objectives: This study evaluated carotid baroreflex sensitivity (cBRS) during graded exercise tests to exhaustion in healthy individuals. It aimed to elucidate whether the augmented blood pressure response during heavy- and maximal-intensi...

(This article belongs to the Special Issue Exercise Physiology and Biochemistry: 3rd Edition)
  • Article
  • Open Access
11 Citations
5,607 Views
22 Pages

The Effect of Skeletal Muscle Oxygenation on Hemodynamics, Cerebral Oxygenation and Activation, and Exercise Performance during Incremental Exercise to Exhaustion in Male Cyclists

  • Evgenia D. Cherouveim,
  • Panagiotis G. Miliotis,
  • Maria D. Koskolou,
  • Konstantina Dipla and ,
  • Ioannis S. Vrabas and
  • Nickos D. Geladas
  • + 1 author+ 0 author

10 July 2023

This study aimed to elucidate whether muscle blood flow restriction during maximal exercise is associated with alterations in hemodynamics, cerebral oxygenation, cerebral activation, and deterioration of exercise performance in male participants. Thi...

(This article belongs to the Special Issue Effects of Physical Exercise on Human Physiology and Pathology)
  • Article
  • Open Access
1 Citations
840 Views
15 Pages

Attentional Bias in Exercise Dependence: An ERP Study of Enhanced Early Attentional Allocation to Exercise Cues

  • Yutong Li,
  • Shiyi Ma,
  • Jiangang Li,
  • Xinning Zhou and ,
  • Jierong Xu,
  • Qianyi Zhang and
  • Hongying Fan
  • + 2 authors+ 0 author

28 January 2026

Exercise dependence is a maladaptive pattern of excessive exercise characterized by psychological and cognitive symptoms. The existence and nature of attentional bias in individuals with exercise dependence remain unclear. This study combined behavio...

(This article belongs to the Section Experimental and Clinical Neurosciences)
  • Article
  • Open Access
15 Citations

Silk peptide treatment can improve the exercise performance of mice

  • Jisu Kim,
  • Hyejung Hwang,
  • Jonghoon Park,
  • Hea-Yeon Yun and ,
  • Heajung Suh and
  • Kiwon Lim
  • + 1 author+ 0 author

Background: We previously reported that silk peptide (SP) treatment led to increased resting fat oxidation in exercised mice. However, it was not known whether SP treatment could effectively increase exercise capacity. Accordingly, this study aimed t...

  • Article
  • Open Access
4 Citations
1,474 Views
11 Pages

10 February 2026

Background and Objectives: Regular exercise improves pain, fatigue, and overall function in individuals with fibromyalgia (FM), yet adherence remains low, especially among employed adults. This study examined symptom and workplace-related factors ass...

(This article belongs to the Section Epidemiology & Public Health)
  • Article
  • Open Access
21 Citations
4,131 Views
15 Pages

Purpose: To explore the influencing factors that restrict the exercise behavior of children and adolescents, investigate the effect of subjective exercise experience on exercise behavior, and reveal the mediating effect of exercise commitment between...

  • Review
  • Open Access
35 Citations
18,784 Views
22 Pages

7 June 2021

Adequate dietary protein is important for many aspects of health with current evidence suggesting that exercising individuals need greater amounts of protein. When assessing protein quality, animal sources of protein routinely rank amongst the highes...

(This article belongs to the Special Issue Sports Nutrition)
  • Article
  • Open Access
3 Citations
4,760 Views
25 Pages

14 November 2022

Exercise products based on universal design, which reduce restrictions on the exercise environment and ensure convenience and safe use, are beneficial for people with a disability; however, the current universal design only considers the preferences...

  • Review
  • Open Access
10 Citations
5,529 Views
32 Pages

10 February 2025

Diabetic cardiomyopathy (DCM) is one of the cardiovascular complications of diabetes, characterized by the development of ventricular systolic and diastolic dysfunction due to factors such as inflammation, oxidative stress, fibrosis, and disordered g...

(This article belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
  • Review
  • Open Access
103 Citations
16,165 Views
11 Pages

There is evidence to suggest that biological sex plays a critical role in memory function, with sex differentially influencing memory type. In this review, we detail the current evidence evaluating sex-specific effects on various memory types. We als...

(This article belongs to the Special Issue The Effects of Exercise on Cognitive Function)
  • Review
  • Open Access
10 Citations
5,036 Views
17 Pages

Exercise Alleviates Aging of Adipose Tissue through Adipokine Regulation

  • Dandan Jia,
  • Huijie Zhang,
  • Tiemin Liu and
  • Ru Wang

22 February 2024

Adipose tissue undergoes changes with aging, leading to increased adiposity, inflammatory cell infiltration, reduced angiogenesis, heightened oxidative stress, and alterations in its metabolic function. Regular exercise has been recognized as a power...

(This article belongs to the Section Endocrinology and Clinical Metabolic Research)
  • Perspective
  • Open Access
9 Citations
5,484 Views
15 Pages

Hypothesized Mechanisms Through Which Exercise May Attenuate Memory Interference

  • Lindsay K. Crawford,
  • Hong Li,
  • Liye Zou,
  • Gao-Xia Wei and
  • Paul D. Loprinzi

14 March 2020

In this paper we introduce a mechanistic model through which exercise may enhance episodic memory, specifically via attenuating proactive and retroactive memory interference. We discuss the various types of memory, different stages of memory function...

  • Article
  • Open Access
56 Citations
12,534 Views
13 Pages

No Effect of Exercise Intensity on Appetite in Highly-Trained Endurance Women

  • Stephanie M. Howe,
  • Taryn M. Hand,
  • D. Enette Larson-Meyer,
  • Kathleen J. Austin and ,
  • Brenda M. Alexander and
  • Melinda M. Manore
  • + 1 author+ 0 author

18 April 2016

In endurance-trained men, an acute bout of exercise is shown to suppress post-exercise appetite, yet limited research has examined this response in women. The purpose of this study was to investigate the effect of exercise intensity on appetite and g...

  • Viewpoint
  • Open Access
15 Citations
6,100 Views
9 Pages

Generalized Approach to Translating Exercise Tests and Prescribing Exercise

  • Carl Foster,
  • James D. Anholm,
  • Daniel Bok,
  • Daniel Boullosa and ,
  • Giancarlo Condello,
  • Cristina Cortis,
  • Andrea Fusco,
  • Salvador J. Jaime,
  • Jos J. de Koning and
  • Jose A. Rodriguez-Marroyo
  • + 8 authors+ 3 authors

Although there is evidence supporting the benefit of regular exercise, and recommendations about exercise and physical activity, the process of individually prescribing exercise following exercise testing is more difficult. Guidelines like % heart ra...

(This article belongs to the Special Issue Exercise Evaluation and Prescription)
  • Review
  • Open Access
17 Citations
4,690 Views
19 Pages

Mitochondrial DNA in Exercise-Mediated Innate Immune Responses

  • Xin Wen,
  • Jingcheng Fan,
  • Xuemei Duan,
  • Xinyi Zhu and ,
  • Jianzheng Bai and
  • Tan Zhang
  • + 1 author+ 0 author

Mitochondria are considered as “the plant of power” with cells for a long time. However, recent researches suggest that mitochondria also take part in innate immune response to a great extent. Remarkably, mtDNA was reported to have immunn...

(This article belongs to the Special Issue Innovative Strategies to Target Metabolism, Inflammation, and Oxidative Stress in Human Diseases)
  • Article
  • Open Access
1 Citations
4,124 Views
16 Pages

Mucosal-Associated Invariant T Cell Response to Acute Exercise and Exercise Training in Older Obese Women

  • Lauren C. Bates,
  • Erik D. Hanson,
  • Michael M. Levitt,
  • Bryan Richie and ,
  • Elise Erickson,
  • David B. Bartlett and
  • Melody D. Phillips
  • + 2 authors+ 0 author

24 September 2021

(1) Background: Obesity is a major global public health concern as it is associated with many of the leading causes of preventable deaths. Exercise reduces obesity-induced inflammation; however, it is unknown how exercise training may impact mucosal...

  • Article
  • Open Access
10 Citations
4,770 Views
12 Pages

6 March 2023

Post-exercise hypotension (PEH) is typically reported as mean values, but a great inter-individual variation in blood pressure (BP) response after a single exercise session is expected, especially when comparing different modalities of exercise. The...

  • Discussion
  • Open Access
72 Citations
46,226 Views
16 Pages

Ketogenic Diets and Exercise Performance

  • Kristin L. Harvey,
  • Lola E. Holcomb and
  • Stephen C. Kolwicz

26 September 2019

The ketogenic diet (KD) has gained a resurgence in popularity due to its purported reputation for fighting obesity. The KD has also acquired attention as an alternative and/or supplemental method for producing energy in the form of ketone bodies. Rec...

(This article belongs to the Special Issue Nutrition and Exercise Metabolism)
  • Article
  • Open Access
6 Citations
3,085 Views
9 Pages

Effects of Acute Exercise on Cutaneous Thermal Sensation

  • Samuel D. Thomas,
  • Howard H. Carter,
  • Helen Jones,
  • Dick H.J. Thijssen and
  • David A. Low

The aim of this study was to assess the effect of exercise intensity on the thermal sensory function of active and inactive limbs. In a randomised and counterbalanced manner, 13 healthy young male participants (25 ± 6 years, 1.8 ± 0.1 m...

(This article belongs to the Special Issue Exercise and Human Temperature Regulation)
  • Article
  • Open Access
21 Citations
24,938 Views
18 Pages

Protein-Pacing and Multi-Component Exercise Training Improves Physical Performance Outcomes in Exercise-Trained Women: The PRISE 3 Study

  • Paul J. Arciero,
  • Stephen J. Ives,
  • Chelsea Norton,
  • Daniela Escudero and ,
  • Olivia Minicucci,
  • Gabe O’Brien,
  • Maia Paul,
  • Michael J. Ormsbee,
  • Vincent Miller and
  • Feng He
  • + 6 authors+ 1 author

1 June 2016

The beneficial cardiometabolic and body composition effects of combined protein-pacing (P; 5–6 meals/day at 2.0 g/kg BW/day) and multi-mode exercise (resistance, interval, stretching, endurance; RISE) training (PRISE) in obese adults has previously b...

(This article belongs to the Special Issue Nutrition, Health and Athletic Performance)
  • Review
  • Open Access
10 Citations
5,805 Views
9 Pages

Lifestyle Modification for Enhancing Autonomic Cardiac Regulation in Children: The Role of Exercise

  • Kathryn E Speer,
  • Nenad Naumovski,
  • Stuart Semple and
  • Andrew J McKune

16 November 2019

Decreased physical activity (PA) is a global concern contributing to the rise in cardiometabolic diseases. One potential mechanism linking insufficient PA and poor health is dysregulated autonomic nervous system (ANS) activity. This relationship is e...

  • Article
  • Open Access
7 Citations

Effect of HX108-CS supplementation on exercise capacity and lactate accumulation after high-intensity exercise

  • Seung-Lyul Oh,
  • Hyukki Chang,
  • Hee-Jae Kim,
  • Yong-An Kim and ,
  • Dong-Sik Kim,
  • Seong-Hyun Ho,
  • Seon-Hee Kim and
  • Wook Song
  • + 3 authors+ 0 author

Background: In the present study, we determined the effects of HX108-CS (mixed extract of Schisandra chinensis and Chaenomeles sinensis) supplementation on lactate accumulation and endurance capacity. Furthermore, we examined CK (creatine kinase), LD...

  • Article
  • Open Access
29 Citations
12 Views

The exercise metabolome: acute aerobic and anaerobic signatures

  • Joseph K. Pellegrino,
  • Tracy G Anthony,
  • Peter Gillies and
  • Shawn M. Arent

Background: Exercise modality differentially alters body composition and physical performance. Metabolic changes underlying these outcomes can be tracked through assessment of circulating metabolites. Here, global responses to an acute bout of aerobi...

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