Special Issue "Progress in Glucose Metabolism"
Deadline for manuscript submissions: 15 February 2021.
Interests: Glucose metabolism; Schizophrenia; moleculare mechanisms of learning; consititutive activity of G Protein-coupled Receptors; trafficking of GPCRs
The concept of glucose metabolism (GM) is well established. Unrecognized didactics rule the established concept. This Special Issue focuses on whether cytosolic-generated NADH-H+ is actually NADH and is directly recovered to NAD+ in the mitochondria or whether more complicated metabolic steps must be considered. Many researchers have different, well-established concepts of GM in mind. In addition to recovery of ATP, glucose and glucose metabolites have been shown to directly trigger the release of interleukins, growth factors, insulin, or TNFa. GAPDH participates in the repair of DNA damage as well as in redox regulation of transcription factors. ATP-driven Ca2+/H+ antiporter and metabolic adenylyl cyclase link GM to Ca2+ and cAMP signaling pathways. The expression of constitutively active G protein-coupled receptors can permanently change GM. Inverse agonists, such as olanzapine, change slowly into muscle fiber, reduce free fatty acid in the blood, and increase the risk of obesity and hyperglycemia. The aim of this Special Issue is to collect a wide range of topics relating to the field of GM. Reviews and experimental manuscripts are welcome. Contrary points of view are welcome and necessary. Please keep in mind colleagues working on enzyme complexes or metabolon; respect their work and do not integrate your data into the well-known line of randomly distributed glycolytic enzymes.
Dr. Dirk Roosterman
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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- glucose metabolism
- monocarboxylic acids
- metabolite channeling
- metabolic signaling pathways
- enzyme complexes
- lactate shuttle