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  • Article
  • Open Access
554 Views
30 Pages

Dental Anxiety Prevalence, Correlates, and Patient-Preferred Management Strategies in Romanian Adults: A Cross-Sectional Survey

  • Laurențiu Drăguș,
  • Magdalena Rusu-Negraia,
  • Simona-Dana Mitincu-Caramfil,
  • Cătălina-Andreea Florea,
  • Ionela-Violeta Ragea,
  • Valeriu Ardeleanu,
  • Ramona-Oana Roșca,
  • Rares Nicolae Vadana and
  • Marius Moroianu

14 July 2026

Background: Dental anxiety constitutes a prevalent barrier to oral healthcare utilization, yet patient-centered data on its prevalence, symptom profile, and preferred management strategies remain scarce in Romanian adult populations. Objectives: This...

  • Article
  • Open Access
1 Citations
2,377 Views
19 Pages

8 April 2025

Background: Dental anxiety is a significant barrier to dental care, leading to avoidance behaviors and compromised oral health. This study aimed to analyze fear and anxiety during dental hygiene visits with Guided Biofilm Therapy (GBT), focusing on g...

(This article belongs to the Section Personalized Therapy and Drug Delivery)
  • Article
  • Open Access
4 Citations
5,587 Views
31 Pages

11 September 2024

Fear and anxiety during dental visits are common issues that can lead to avoidance of appointments and deterioration of oral health. Effectively managing patients’ emotions during dental treatments is crucial to improving their experiences, inc...

(This article belongs to the Special Issue State-of-the-Art Operative Dentistry)
  • Article
  • Open Access
44 Citations
7,856 Views
11 Pages

Portuguese Nurses’ Stress, Anxiety, and Depression Reduction Strategies during the COVID-19 Outbreak

  • Lara Guedes de Pinho,
  • Francisco Sampaio,
  • Carlos Sequeira,
  • Laetitia Teixeira,
  • César Fonseca and
  • Manuel José Lopes

The COVID-19 pandemic has contributed to mental health problems worldwide. Nurses are particularly prone to stress because they directly care for individuals with suspected or confirmed cases of COVID-19. The aims of this study were (a) to explore th...

(This article belongs to the Special Issue Socioeconomic Status and Lifestyles as Determinants of Mental Health during the COVID-19 Outbreak)
  • Article
  • Open Access
15 Citations
6,569 Views
25 Pages

Background: Respiratory sinus arrhythmia (RSA) denotes decrease of cardiac beat-to-beat intervals (RRI) during inspiration and RRI increase during expiration, but an inverse pattern (termed negative RSA) was also found in healthy humans with elevated...

(This article belongs to the Special Issue Genetic, Epigenetic, Environmental, and Pharmacological Models for Neuroscience, Neurologic Diseases, and Psychiatric Disorders: Advancement in Bench-to-Bedside Translational Research)
  • Article
  • Open Access
9 Citations
4,667 Views
10 Pages

Effectiveness of Compassion Training on Stress and Anxiety: A Pre-Experimental Study on Nursing Students

  • Andrés Gutiérrez-Carmona,
  • Marta González-Pérez,
  • María Dolores Ruiz-Fernández,
  • Angela María Ortega-Galán and
  • Diego Henríquez

27 November 2024

Background: Stress and anxiety are common problems among nursing students, affecting their mental health and academic performance. Compassion training has been shown to be effective in reducing these states. Objectives: This study evaluated the effec...

  • Article
  • Open Access
1 Citations
3,173 Views
12 Pages

Anxiety and Bodily Pain in Older Women Participants in a Physical Education Program. A Multiple Moderated Mediation Analysis

  • Óscar Chiva-Bartoll,
  • Honorato Morente-Oria,
  • Francisco Tomás González-Fernández and
  • Pedro Jesús Ruiz-Montero

15 May 2020

(1) Background: Bodily pain is normally associated with the consequences of ageing, whereas anxiety shows a high prevalence in elderly people, decreasing the health-related quality of life (HRQoL). Pain coping strategies are used to reduce the conseq...

(This article belongs to the Special Issue Active Aging: Educational Innovations in the Elderly)
  • Communication
  • Open Access
17 Citations
4,201 Views
11 Pages

An Intervention on Anxiety Symptoms in Moderate Alzheimer’s Disease through Virtual Reality: A Feasibility Study and Lessons Learned

  • Desirée Sánchez-Nieto,
  • Sergio Castaño-Castaño,
  • Remedios Navarro-Martos,
  • Esteban Obrero-Gaitán,
  • Irene Cortés-Pérez and
  • Francisco Nieto-Escamez

(1) Background: Although cognitive impairment is considered the core deficit of dementia, anxiety disorders also have a negative influence on the social and daily life of the affected population. We have explored the exposure of relaxing scenarios in...

  • Article
  • Open Access
13 Citations
6,428 Views
17 Pages

This study aimed to investigate how psychological anxiety caused by COVID-19 has influenced airline cabin crew job self-esteem and job satisfaction. A questionnaire based on prior research was developed to identify factors of psychological anxiety am...

(This article belongs to the Special Issue Satisfaction, Stress, and Mental Health in the Tourism/Hospitality Industry)
  • Article
  • Open Access
102 Citations
15,463 Views
15 Pages

Religious Coping, Depression and Anxiety among Healthcare Workers during the COVID-19 Pandemic: A Malaysian Perspective

  • Soon Ken Chow,
  • Benedict Francis,
  • Yit Han Ng,
  • Najmi Naim,
  • Hooi Chin Beh,
  • Mohammad Aizuddin Azizah Ariffin,
  • Mohd Hafyzuddin Md Yusuf,
  • Jia Wen Lee and
  • Ahmad Hatim Sulaiman

Anxiety and depression have been prevalent among Healthcare Workers (HCWs) amidst the COVID-19 pandemic. This study aims to evaluate the prevalence of anxiety and depression among HCWs amid the pandemic and their association with religious coping. A...

(This article belongs to the Special Issue COVID-19 Pandemic: Challenges Facing the Health System)
  • Article
  • Open Access
7 Citations
3,286 Views
18 Pages

Effects of Active Gamification on Sleep and Anxiety Reduction in Spanish Primary School Children

  • María del Carmen Carcelén-Fraile,
  • Alberto Ruiz-Ariza,
  • Alba Rusillo-Magdaleno and
  • Agustín Aibar-Almazán

Background/Objectives: Active gamification, which incorporates game elements with physical interaction, is presented as an innovative strategy to address anxiety problems and sleep quality in children. This study aimed to evaluate the impact of an ac...

(This article belongs to the Special Issue Physical Activity, Sleep, and Nutrition for Health in Children and Adolescents)
  • Article
  • Open Access
41 Citations
10,482 Views
15 Pages

Virtual Reality Nature Exposure and Test Anxiety

  • Alison O’Meara,
  • Marica Cassarino,
  • Aaron Bolger and
  • Annalisa Setti

The number of students affected by exam anxiety continues to rise. Therefore, it is becoming progressively relevant to explore innovative remediation strategies that will help mitigate the debilitating effects of exam anxiety. The study aimed to inve...

(This article belongs to the Special Issue 3D Human–Computer Interaction)
  • Article
  • Open Access
1 Citations
2,864 Views
8 Pages

Impact of Inquiry-Based Stress Reduction Intervention on Pharmacy Students’ Test Anxiety

  • Martha Ndung’u,
  • Suzanne Galal,
  • Emily Tran,
  • Matissa Peng,
  • Jeffrey Chang,
  • Deepti Vyas,
  • John Mayberry and
  • Avneet Kaur Chima

23 December 2024

Test anxiety is a significant issue among pharmacy students, potentially affecting their academic performance and well-being. This study aimed to evaluate the effectiveness of an Inquiry-Based Stress Reduction (IBSR) intervention in reducing test anx...

  • Article
  • Open Access
1 Citations
12,724 Views
10 Pages

The Effects of Vagus Nerve Stimulation on Stress, Competitive Anxiety, and Depression in Elite Shooters: Randomized Controlled Trial

  • Sang-Hyuk Park,
  • Changhoon Seong,
  • Nyeonju Kang,
  • Kyoungkyu Jeon,
  • Sekee Kil,
  • Hyosung Ahn and
  • Seung-Taek Lim

19 August 2025

This study aimed to determine whether vagus nerve stimulation is effective in modulating psychological states such as anxiety, depression, and stress in elite shooters. A total of 18 female elite shooters (aged 18–19 years) were randomly assign...

(This article belongs to the Special Issue Human Performance in Sports and Training)
  • Article
  • Open Access
11 Citations
4,704 Views
8 Pages

Non-Pharmacological Interventions for Reducing Anxiety in Patients with Potentially Malignant Oral Disorders

  • Elia Lopez-Yufera,
  • Pia López-Jornet,
  • Oscar Toralla and
  • Eduardo Pons-Fuster López

26 February 2020

Objective: To evaluate the effect of a music intervention upon anxiety, blood pressure, and heart rate in adult patients with potentially malignant oral disorders. Methods: Eighty consecutive adults (mean age: 68.3 years) consulting a Unit of Oral Me...

(This article belongs to the Section Mental Health)
  • Article
  • Open Access
24 Citations
11,177 Views
24 Pages

6 December 2022

Psychosocial working conditions such as long work hours, low job control, and work–life imbalance faced by construction professionals in site management positions subject them to elevated work stress and poor mental health. This study explored...

(This article belongs to the Special Issue Occupational Health and Diseases in Built Environment)
  • Article
  • Open Access
5 Citations
6,633 Views
30 Pages

The COVID-19 pandemic brought significant challenges to university students in China, including the Hong Kong Special Administrative Region. To understand the stress and coping strategies of university students during the pandemic, we conducted focus...

(This article belongs to the Section Behavioral and Mental Health)
  • Article
  • Open Access
16 Citations
3,928 Views
18 Pages

22 May 2025

Technological development in artificial intelligence (AI) has significantly transformed the learning context, and university-level students are now required to possess AI literacy. Effective research, however, has not been conducted to study factors...

(This article belongs to the Section Sustainable Education and Approaches)
  • Article
  • Open Access
1,085 Views
33 Pages

International students at English-medium universities in Australia whose first language is not English often struggle with language learning due to challenges sustaining motivation and managing anxiety, while simultaneously needing to strengthen thei...

  • Study Protocol
  • Open Access
13 Citations
6,998 Views
11 Pages

Pharmacogenetically Guided Escitalopram Treatment for Pediatric Anxiety Disorders: Protocol for a Double-Blind Randomized Trial

  • Jeffrey R. Strawn,
  • Ethan A. Poweleit,
  • Jeffrey A. Mills,
  • Heidi K. Schroeder,
  • Zoe A. Neptune,
  • Ashley M. Specht,
  • Jenni E. Farrow,
  • Xue Zhang,
  • Lisa J. Martin and
  • Laura B. Ramsey

12 November 2021

Current pharmacologic treatments for pediatric anxiety disorders (e.g., selective serotonin reuptake inhibitors (SSRIs)) frequently use “one size fits all” dosing strategies based on average responses in clinical trials. However, for some SSRIs, incl...

(This article belongs to the Special Issue Pharmacogenetics of Treating Anxiety & Depression)
  • Brief Report
  • Open Access
13 Citations
5,520 Views
8 Pages

Brief COPE Short Version (Mini-COPE): A Proposal of Item and Factorial Reduction in Mexican Population

  • Aniel Jessica Leticia Brambila-Tapia,
  • Reyna Jazmin Martínez-Arriaga,
  • Joel Omar González-Cantero,
  • Victor Hugo González-Becerra,
  • Yesica Arlae Reyes-Domínguez,
  • María Luisa Ramírez-García and
  • Fabiola Macías-Espinoza

The factorial reduction of Brief COPE has not been successfully replicated by independent studies, and few have been performed in Spanish-speaking populations; therefore, the objective of this study was to perform a factorial reduction of the instrum...

(This article belongs to the Special Issue Mental Health Matters: From Cross-Cultural Perspectives)
  • Article
  • Open Access
12 Citations
5,009 Views
23 Pages

This study examined the use of virtual reality (VR) scaffolding in English as a Foreign Language (EFL) instruction, focusing on its effects on speaking anxiety and learner perceptions and the need for tailored assessment methods. The study involved 3...

  • Article
  • Open Access
2,102 Views
14 Pages

Focused Attention Meditation as a Pre-Exercise Strategy for Reducing Anxiety in Speed Skaters

  • Yosuke Tomita,
  • Mari Yokoo,
  • Kaori Shimoda,
  • Tomoki Iizuka,
  • Eikichi Sakamoto,
  • Koichi Irisawa,
  • Fusae Tozato and
  • Kenji Tsuchiya

11 January 2026

Anxiety is a common psychological challenge among athletes, particularly in response to intense training sessions. This randomized crossover study investigated the immediate effects of a single session of focused attention meditation on anxiety, auto...

(This article belongs to the Collection Sensor Technology for Sports Science)
  • Article
  • Open Access
11 Citations
6,463 Views
25 Pages

31 December 2024

Background: Dentistry and nursing students experience significant anxiety, negatively impacting their well-being and academic performance. Objectives: This study aims to assess the prevalence and relationships of stress, anxiety, depression, resilien...

(This article belongs to the Special Issue Towards Holistic Healthcare: Advancing Nursing and Medical Education)
  • Article
  • Open Access
1,496 Views
18 Pages

Climate Change Anxiety: Drivers, Impact, and Mitigation Interventions—A Multi-Country Survey

  • Opeyemi O. Deji-Oloruntoba,
  • Adefarati Oloruntoba,
  • Helen B. Binang and
  • Olusanya Olaseinde

Climate change is increasingly recognized as a source of psychological distress, yet the prevalence, predictors, and behavioral implications of climate anxiety remain unevenly understood. This study examines climate anxiety, its key drivers, and asso...

(This article belongs to the Section Psychology of Sustainability and Sustainable Development)
  • Article
  • Open Access
7 Citations
4,971 Views
19 Pages

Repetitive and Inflexible Active Coping and Addiction-like Neuroplasticity in Stressed Mice of a Helplessness–Resistant Inbred Strain

  • Simona Cabib,
  • Paolo Campus,
  • Emanuele Claudio Latagliata,
  • Cristina Orsini and
  • Valeria Tarmati

10 December 2021

Dysfunctional coping styles are involved in the development, persistence, and relapse of psychiatric diseases. Passive coping with stress challenges (helplessness) is most commonly used in animal models of dysfunctional coping, although active coping...

(This article belongs to the Section Biological Psychiatry)
  • Commentary
  • Open Access
58 Citations
12,887 Views
7 Pages

12 September 2020

The raging COVID-19 pandemic has been a great source of anxiety, distress, and stress among the population. Along with mandates for social distancing and infection control measures, the growing importance of managing and cultivating good mental well-...

(This article belongs to the Special Issue COVID-19 Pandemic: Challenges Facing the Health System)
  • Article
  • Open Access
4 Citations
3,508 Views
11 Pages

1 February 2024

Examination stress is the most common stressor reported by adolescents across the globe. Exam stress involves mental distress related to anticipated academic challenges or fear of failure in the examinations, test anxiety, or fear of being unable to...

(This article belongs to the Special Issue Depression, Anxiety and Stress in Children and Adolescents: 2nd Edition)
  • Article
  • Open Access
341 Views
14 Pages

11 August 2026

Background/Objectives: Depression and anxiety are common among individuals with type 2 diabetes mellitus (T2DM) and are associated with poorer clinical outcomes. Although diabetes stigma and perceived social support have been linked to psychological...

  • Article
  • Open Access
900 Views
20 Pages

Effects of Simulated Video Consultation Training on Nursing Students’ Clinical Decision Making, Self-Confidence, and Anxiety: A Quasi-Experimental Study

  • Glòria Tort-Nasarre,
  • Alícia Baltasar-Bagué,
  • Maria del Carmen Malagón-Aguilera,
  • Mariona Vilar-Pont,
  • Carla Camí and
  • Glòria Reig-Garcia

Background: The expansion of telenursing in primary care requires undergraduate nursing programmes to prepare students for clinical decision making in virtual care. However, evidence on educational interventions integrating clinical reasoning with ma...

  • Article
  • Open Access
2 Citations
4,835 Views
23 Pages

Improving Anxiety Related to Chronic Pain Through a Sleep Circadian Intervention Program: A Pilot Study

  • Sonia López-Monzoni,
  • Gloria Hernando Benito,
  • Sofía Romero-Peralta,
  • Laura Silgado-Martínez,
  • Maria Esther Viejo-Ayuso,
  • Leticia Álvarez-Balado,
  • Enrique Rodríguez Matarranz,
  • Carles Forné Izquierdo,
  • Manuel Sánchez-de-la-Torre and
  • Olga Mediano
  • + 6 authors

3 January 2025

The limitations of pharmacological treatments for chronic pain have become increasingly evident: dependency, side effects, resistance, and diminishing efficacy. The urgent need for innovative solutions has become a compelling focus for improving pati...

  • Brief Report
  • Open Access
17 Citations
11,046 Views
8 Pages

COVID-19 Pandemic and the Burden of Internet Addiction in the United States

  • Jagdish Khubchandani,
  • Sushil Sharma and
  • James H. Price

Despite the extensive usage of the internet, little is known about internet addiction among Americans during the pandemic. A valid and reliable questionnaire was deployed online via MTurk to recruit a national sample of adult Americans to understand...

  • Article
  • Open Access
5 Citations
2,626 Views
10 Pages

19 September 2025

Background: This cross-sectional study investigated the associations between medication-induced xerostomia (perceived oral dryness) and intraoral painful aching in 141 middle-aged adults (45–64 years) with self-reported xerostomia resulting fro...

(This article belongs to the Special Issue Innovative Clinical Approaches in Oral Health Prevention and Management)
  • Article
  • Open Access
45 Citations
19,141 Views
12 Pages

Mental health conditions in childhood and adolescence are increasing in the U.S. population and require early intervention, as highlighted by a recent Surgeon General’s Advisory on Protecting Youth Mental Health. These health issues, which have...

(This article belongs to the Special Issue Maternal, Newborn, Child and Family Health: Past, Present, and Future)
  • Systematic Review
  • Open Access
1 Citations
1,988 Views
12 Pages

Systematic Review and Meta-Analysis of Milk Fat Globule Membrane Supplementation for Mental Well-Being

  • Charlotte Mawson,
  • Andrew M. Carroll,
  • Stefanie Evas,
  • Sarah J. Spies and
  • Maher Fuad

21 January 2026

Background/Objectives: The milk fat globule membrane (MFGM) is a complex structure of polar lipids, gangliosides, and glycoproteins that has demonstrated anti-inflammatory, neuroprotective, and gut-modulatory effects in preclinical and human studies,...

(This article belongs to the Topic Bioactive Compounds with Application Potentials in Nutraceuticals and Nutricosmetics: Focus on Mechanism of Action and Application Science—2nd Edition)
  • Review
  • Open Access
8 Citations
9,895 Views
19 Pages

Efficacy and Safety of Agomelatine in Depressed Patients with Diabetes: A Systematic Review and Meta-Analysis

  • Adam Gędek,
  • Szymon Modrzejewski,
  • Michał Materna,
  • Zofia Szular,
  • Adam Wichniak,
  • Paweł Mierzejewski and
  • Monika Dominiak

25 November 2024

Major depressive disorder (MDD) and diabetes mellitus (DM) remain among the most prevalent diseases and the most significant challenges faced by medicine in the 21st century. The frequent co-occurrence and bidirectional relationship between the two c...

(This article belongs to the Special Issue Molecular Pharmacology of Human Metabolism Diseases)
  • Article
  • Open Access
31 Citations
15,587 Views
18 Pages

Nature Tourism and Mental Well-Being: Insights from a Controlled Context on Reducing Depression, Anxiety, and Stress

  • Imelda Avecillas-Torres,
  • Sebastián Herrera-Puente,
  • Miguel Galarza-Cordero,
  • Fernanda Coello-Nieto,
  • Karina Farfán-Pacheco,
  • Byron Alvarado-Vanegas,
  • Stephany Ordóñez-Ordóñez and
  • Freddy Espinoza-Figueroa

16 January 2025

Recent studies have underscored the importance of tourism in enhancing individuals’ mental well-being through engagement with nature. This article examines the impact of nature-based tourism on alleviating symptoms of depression, anxiety, and s...

(This article belongs to the Section Health, Well-Being and Sustainability)
  • Article
  • Open Access
13 Citations
7,111 Views
23 Pages

Substance Use and Mental Health in Emerging Adult University Students Before, During, and After the COVID-19 Pandemic in Mexico: A Comparative Study

  • Gustavo A. Hernandez-Fuentes,
  • Jessica C. Romero-Michel,
  • Veronica M. Guzmán-Sandoval,
  • Janet Diaz-Martinez,
  • Osiris G. Delgado-Enciso,
  • Ruth R. Garcia-Perez,
  • Monserrat Godínez-Medina,
  • Vicente Zamora-Barajas,
  • Angel G. Hilerio-Lopez and
  • Ivan Delgado-Enciso
  • + 7 authors

27 November 2024

Background: The COVID-19 pandemic significantly impacted mental health and substance use patterns, particularly among young adults. Objective: This study aimed to assess changes in anxiety, depression, self-esteem, and substance use among university...

  • Systematic Review
  • Open Access
3 Citations
4,657 Views
18 Pages

Animal-Assisted Therapy for Reducing Anxiety in Vulnerable Clinical Populations: A Systematic Review

  • Nazaret Hernández-Espeso,
  • Laura Durbán Bronchud and
  • Gloria Bernabé-Valero

21 January 2026

Background: Anxiety is highly prevalent among individuals living with disability, chronic illness, or hospitalisation, yet it often remains insufficiently addressed in healthcare settings. Animal-assisted therapy (AAT) has been proposed as a compleme...

(This article belongs to the Special Issue Human–Animal Interaction: Animal Behaviour and Whole-Person Health in Animal-Assisted Interventions)
  • Article
  • Open Access
11 Citations
5,149 Views
16 Pages

Preventive Effect of a 7-Week App-Based Passive Psychoeducational Stress Management Program on Students

  • Elisabeth M. Weiss,
  • Siegmund Staggl,
  • Bernhard Holzner,
  • Gerhard Rumpold,
  • Verena Dresen and
  • Markus Canazei

25 February 2024

Passive psychoeducation is an easily accessible and cost-effective self-guided intervention that does not use elements of active psychotherapies or require homework. The present study aimed to investigate the acceptability and efficacy of a 7-week ap...

(This article belongs to the Special Issue Psychoeducation and Early Intervention)
  • Review
  • Open Access

Die Behandlung der generalisierten Angststörung. Ein bio-psychosozialer Therapieschulen-übergreifender Ansatz

  • Ulrich T. Egle,
  • Tobias Ballweg,
  • Isabelle Bättig,
  • Joel Neufeld and
  • Katja Cattapan

The treatment of generalised anxiety disorder. A biopsychosocial approach across therapeutic schools. The coronavirus pandemic has led many people to experience an existential threat and triggered different forms of coping with this persistent stress...

  • Review
  • Open Access
4 Citations
6,635 Views
17 Pages

29 January 2025

Background: Children with special needs often need tailored approaches to oral healthcare to address their unique needs effectively. It is essential to analyze the effectiveness of non-pharmacological management in reducing dental anxiety among speci...

(This article belongs to the Section Pediatric Dentistry & Oral Medicine)
  • Article
  • Open Access
7 Citations
6,867 Views
15 Pages

Virtual Reality and Relaxation for the Treatment of Generalized Anxiety Disorder: A Randomized Comparative Study with Standard Intervention

  • Eric Malbos,
  • Nadège Chichery,
  • Baptiste Borwell,
  • Gabriel Weindel,
  • Jordan Molitor,
  • Mélodie Einig-Iscain,
  • Julien Seimandi and
  • Christophe Lançon

18 February 2025

Background/Objectives: Modern therapeutic strategies incorporating virtual reality (VR) have emerged as potential treatments for generalized anxiety disorder (GAD), a prevalent and debilitating condition that is challenging to cure. This study aimed...

(This article belongs to the Section Mental Health)
  • Article
  • Open Access
823 Views
18 Pages

Personalised Nutraceutical Treatment Guided by MTHFR Genotype in Mental Health: A Retrospective Cohort Study

  • Cristina Beer,
  • Fiona Rae,
  • Mikayla Watt,
  • Maciej Trzaskowski,
  • Clarissa Yates,
  • Annalese Semmler and
  • Joanne Voisey

26 August 2026

Background & Aims: One-carbon metabolism plays a central role in neurotransmitter synthesis, methylation capacity, and neurobiological resilience. Variants in the methylenetetrahydrofolate reductase (MTHFR) gene can reduce enzymatic activity, aff...

(This article belongs to the Special Issue Nutritional Psychiatry: Nutrition, Neurobiological Function, and Mental Well-Being)
  • Article
  • Open Access
9 Citations
4,238 Views
24 Pages

Effects of NADPH Oxidase Isoform-2 (NOX2) Inhibition on Behavioral Responses and Neuroinflammation in a Mouse Model of Neuropathic Pain

  • Luísa Teixeira-Santos,
  • Eduardo Veríssimo,
  • Sandra Martins,
  • Teresa Sousa,
  • António Albino-Teixeira and
  • Dora Pinho

NADPH oxidase isoform-2 (NOX2) has been implicated in the pathophysiology of neuropathic pain (NP), mostly through the modulation of neuroinflammation. Since it is also accepted that some neuroimmune mechanisms underlying NP are sex-dependent, we aim...

(This article belongs to the Special Issue Molecular Mechanisms of Chronic Pain and New Therapeutic Strategies)
  • Article
  • Open Access
372 Views
16 Pages

A Pilot Study of a Video Cognitive Behavioral Intervention in Spanish and English for Chronic Kidney Disease Patients

  • Olivia B. Friedman,
  • Jairo N. Fuertes,
  • Michael T. Moore,
  • Sofia Rubinstein and
  • Theudia Chambers

This study presents a slide-based video cognitive behavioral therapy (CBT)-informed psychoeducational intervention for chronic kidney disease (CKD) and end-stage kidney disease (ESKD) patients. The intervention addresses the lack of mental healthcare...

  • Article
  • Open Access
23 Citations
9,691 Views
11 Pages

The aim of the present pilot study was to assess the effect of a brief work-related self-affirming implementation intention (WS-AII) on the well-being of primary school teachers. Participants were randomly allocated to one of two conditions: one in w...

(This article belongs to the Special Issue Occupational Stress, Human Health and Wellbeing)
  • Article
  • Open Access
3 Citations
2,855 Views
24 Pages

Early Rehabilitation Versus Conventional Approaches in Post-Traumatic Hand Injuries with Multiple Lesions: Clinical Outcomes and Future Directions

  • Adriana Serban,
  • Andreea Grosu-Bularda,
  • Eliza-Maria Bordeanu-Diaconescu,
  • Georgiana-Ozana Tache and
  • Marius Stoica

19 November 2025

Background and Objectives: Complex hand injuries often lead to long-term functional impairment and require structured rehabilitation following surgery. While early rehabilitation may improve outcomes by preventing stiffness and adhesions, it can also...

(This article belongs to the Special Issue Recent Research and Trends in Plastic, Aesthetic and Regenerative Surgery)
  • Article
  • Open Access
962 Views
18 Pages

Topical Pregabalin in Burning Mouth Syndrome: A Real-World Study of Peripheral Neuromodulation

  • Federica Canfora,
  • Antonietta Argiuolo,
  • Simona Salerno,
  • Claudia Castellucci,
  • Roberta Evangelista,
  • Salvatore Ferrara,
  • Rosa Valletta,
  • Alfredo De Rosa,
  • Lucia Memè and
  • Daniela Adamo
  • + 1 author

5 July 2026

Background and Objectives: Burning Mouth Syndrome (BMS) remains a challenging condition to manage, as current treatments show variable efficacy and are often limited by tolerability, particularly in older and medically complex patients. This has prom...

(This article belongs to the Special Issue New Advances in Oral Care)
  • Article
  • Open Access
16 Citations
4,767 Views
18 Pages

Predictors of Psychological Distress in Women with Endometriosis during the COVID-19 Pandemic

  • Roxana Schwab,
  • Kathrin Stewen,
  • Laura Ost,
  • Tanja Kottmann,
  • Susanne Theis,
  • Tania Elger,
  • Mona Wanda Schmidt,
  • Katharina Anic,
  • Stefanie Roxana Kalb and
  • Annette Hasenburg
  • + 1 author

Background: Endometriosis is a multifaceted chronic pain condition that can have a negative impact on mental health. Patients suffering from chronic pain may face an additional psychological burden during adversity, such as the COVID-19 pandemic. The...

(This article belongs to the Section Health Behavior, Chronic Disease and Health Promotion)

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