Innovative Clinical Approaches in Oral Health Prevention and Management

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Dentistry, Oral Surgery and Oral Medicine".

Deadline for manuscript submissions: 25 July 2025 | Viewed by 1368

Special Issue Editors


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Guest Editor
Department of Clinical Sciences and Stomatology (DISCO), Università Politecnica delle Marche, 60126 Ancona, Italy
Interests: dental materials; pediatric dentistry; restorative dentistry; vibrational spectroscopy; biomaterials; high-resolution analytical techniques; remineralizing agents

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Guest Editor
Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, 56126 Pisa, Italy
Interests: oral medicine; oral surgery; clinical dentistry; intraoral ultrasonography; diagnostic imaging
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Special Issue Information

Dear Colleagues,

I invite you to submit a contribution for a Special Issue on “Innovative Clinical Approaches in Oral Health Prevention and Management” in the Journal of Clinical Medicine.

Oral health plays a crucial role in sustaining overall health, well-being, and quality of life. Despite significant advances in dental care, oral diseases remain among the most prevalent health conditions globally, affecting individuals across all age groups and socioeconomic backgrounds.

The focus of this Special Issue involves oral health, preventive strategies, innovative approaches, and their implications for current clinical practices, as well as the state of oral health literacy and policy. It aims to encourage contributions from researchers, clinicians, and policymakers to expand knowledge, improving both preventive and therapeutic approaches in oral health.

In this Special Issue, we welcome authors to submit papers on oral health prevention and management, clinical application of innovative biomaterials and clinical procedures used in preventive dentistry, and multidisciplinary and translational collaboration in oral healthcare. Original articles and reviews are all welcome for submission. 

Dr. Giulia Orilisi
Dr. Rossana Izzetti
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • oral health
  • oral prevention
  • teeth remineralization
  • oral pathology
  • oral health management
  • preventive dentistry
  • translational dentistry

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Published Papers (2 papers)

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Research

11 pages, 222 KiB  
Article
Clinical Features and Patient-Reported Outcomes in a Cohort of Patients with Sjögren’s Disease
by Rossana Izzetti, Chiara Cinquini, Giovanni Fulvio, Marco Nisi, Chiara Baldini and Antonio Barone
J. Clin. Med. 2025, 14(6), 2027; https://doi.org/10.3390/jcm14062027 - 17 Mar 2025
Viewed by 329
Abstract
Background: Sjögren’s disease (SD) is an autoimmune condition causing progressive salivary and lacrimal glands dysfunction following lymphocytic infiltration in the glandular tissue. SD patients are more prone to oral health impairment due to a reduction in salivary flow. This study evaluated the [...] Read more.
Background: Sjögren’s disease (SD) is an autoimmune condition causing progressive salivary and lacrimal glands dysfunction following lymphocytic infiltration in the glandular tissue. SD patients are more prone to oral health impairment due to a reduction in salivary flow. This study evaluated the relationship between oral health, functional tests, and patient reported outcomes in a cohort of SD patients. Methods: Patients diagnosed with SD underwent complete dental examination, with the recording of the decayed–missing–filled teeth index (DMFT), probing pocket depth (PPD), full mouth bleeding score (FMBS), and full mouth plaque score (FMPS). Hyposalivation was assessed using the unstimulated whole saliva flow rate (UWS). Patients were administered the European League Against Rheumatism (EULAR) Sjögren’s Syndrome Patient Reported Index, EULAR Sjögren’s syndrome disease activity index, Oral Health Impact Profile-14 (OHIP-14), Patient Acceptable Symptom State questionnaires, and a visual analog scale for xerostomia (VASx). Results: Fifty patients in total were enrolled. Reduced UWS was associated with higher DMFT, FMBS, and FMPS. Significant correlation was observed for UWS with VASx and OHIP-14 (p < 0.05). Conclusions: Quality of life and oral health appear mildly impaired in SD patients as an effect of reduced salivary flow, with higher DMFT and tendency towards gingival inflammation and plaque accumulation. Full article
13 pages, 1237 KiB  
Article
Leveraging Dental Visits for Systemic Health: Diabetes Screening and Referral Compliance in Periodontitis Patients in Malaysia
by Nur Adila Mohd Norwir, Shahida Mohd-Said, Aznida Firzah Abdul Aziz and Tuti Ningseh Mohd-Dom
J. Clin. Med. 2025, 14(3), 739; https://doi.org/10.3390/jcm14030739 - 23 Jan 2025
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Abstract
Background/Objectives: Opportunistic diabetes screening in dental clinics is an innovative strategy with significant public health implications. Methods: This prospective observational study assessed diabetes risk and referral compliance among periodontitis patients using the Finnish Diabetes Risk Score (FINDRISC) and capillary fasting blood [...] Read more.
Background/Objectives: Opportunistic diabetes screening in dental clinics is an innovative strategy with significant public health implications. Methods: This prospective observational study assessed diabetes risk and referral compliance among periodontitis patients using the Finnish Diabetes Risk Score (FINDRISC) and capillary fasting blood glucose (cFBG). Patients with FINDRISC ≥ 11 and/or cFBG ≥ 5.6 mmol/L were classified as high-risk and referred for further medical evaluation, with compliance tracked through medical practitioner feedback. Results: A total of 142 participants were recruited by 20 general dental practitioners (GDPs). Of these, 36.4% (n = 47) had a FINDRISC ≥ 11, with a mean score of 7.7 ± 4.5, and 26.3% (n = 34/129) had cFBG levels ≥ 5.6 mmol/L. There was no significant difference between periodontal status and FINDRISC (p = 0.291) or between periodontal status and cFBG (p = 0.129). Overall, 54 patients (41.8%) were referred for follow-up, with 33 (61.1%) completing the process. Among those who completed referrals, 10 (30.3%) were diagnosed with prediabetes and seven (21.2%) with diabetes. Non-compliance was more common among patients from lower socioeconomic backgrounds. Conclusions: This study shows the feasibility of integrating diabetes risk screening into private dental practice and its potential to identify high-risk individuals. Shared care models and policy adaptations are essential to improve interdisciplinary collaboration and overcome referral compliance barriers. Full article
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