In this study, the crystallization of scandium from ammonium fluoride strip liquor, obtained by solvent extraction, was investigated using an anti-solvent crystallization technique. Acetone, ethanol, methanol and isopropanol were added individually t...
Clopidogrel bisulfate (CLP) form-I crystals are irregular, rectangular-shaped crystals. Because of their poor compressibility, flowability and their strong surface tension, manufacturers apply spherical crystallization methods to produce CLP form-I s...
Potassium-containing feldspars provide a high potential for producing potash, a product with widespread use in agriculture. The present work assesses applying the anti-solvent crystallization method for the purification and recovery of high-purity mu...
The reverse addition process in anti-solvent crystallization is safer and more efficient than sieving when dealing with energetic compounds. A new mathematical model has been developed to understand the crystal size mechanism during the reverse addit...
The increasing demand for lithium-ion batteries (LIBs) has intensified the need for efficient lithium (Li) recovery from secondary sources. This study focuses on anti-solvent crystallization for the recovery of high-purity lithium hydroxide monohydra...
Background: The therapeutic efficiency of cefquinome is currently limited by the low solubility and short half-life of its commercial sulfate form (SCFQ). This study aimed to improve these properties by preparing a novel crystalline cefquinome free a...
A facile and low-cost strategy to fabricate CsPbBr3 single crystals is essential for developing perovskite optoelectronic devices. Herein, we have presented a room temperature anti-solvent precipitate method for growing sub-centimeter-sized CsPbBr3 s...
Solution-processed organic-inorganic halide perovskites are currently established as the hottest area of interest in the world of photovoltaics, ensuring low manufacturing cost and high conversion efficiencies. Even though various fabrication/deposit...
Anti-solvent crystallization is frequently applied in pharmaceutical processes for the separation and purification of intermediate compounds and active ingredients. The selection of optimal solvent types is important to improve the economic performan...
Regulating the crystallization dynamics of perovskite films is key to improving the efficiency and operational stability of (FA0.83MA0.17Cs0.05)Pb(I0.85Br0.15)3 perovskite solar cells (PSCs). However, precise regulation of the crystallization process...
Currently, one of the key challenges in the pharmaceutical industry is the transformation of traditional batch production methods into robust continuous processes with the intention of reducing manufacturing costs and time and improving product quali...
Protein crystallization plays a crucial role in the food and pharmaceutical industries, enhancing product quality and efficiency by improving purity and controlled particle characteristics. This study focused on the crystallization of the versatile p...
Coal resources still occupy a dominant position in the energy consumption structure, and the prevention and control of coal dust explosion has become an important measure to ensure the safe production of coal. To this end, a new type of environmental...
Antisolvent crystallization is commonly used in the formation of heat-sensitive compounds as it is the case for most active pharmaceutical ingredients. Membranes have the ability to control the antisolvent mass transfer to the reaction medium, provid...
Metal halide perovskite both in the form of nanocrystal and thin films recently emerged as the most promising semiconductor material covering a huge range of potential applications from display technologies to photovoltaics. Colloidal inorganic and o...
The development of an antisolvent crystallization process requires the construction of an accurate phase diagram for this ternary system of compound, solvent and antisolvent, preferably as a function of temperature. This study gives an efficient meth...
Recovering scandium from hydrometallurgical residue bears the potential of a better supply of an industry depending on imports from countries with more mineral resources than Europe. To recover scandium from unused metal production residue, strip liq...
Crystallization is one of the most important methods in the crystal habit control of explosive products. For this study, the antisolvent crystallization experiments were carried out to tune the crystal habits of 2,6-dimaino-3,5-dinitropyrazine-1-oxid...
Solid multicomponent systems (SMS) are gaining an increasingly important role in the pharmaceutical industry, to improve the physicochemical properties of active pharmaceutical ingredients (APIs). In recent years, various processes have been employed...
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Aprepitant (APT), an antiemetic drug used for chemotherapy-induced nausea and vomiting (CINV), exhibits poor compressibility, solubility, and micromeritic properties. Crystal habit modification was studied using solvent evaporation, conventional anti...
The emergence of artificial neural networks and the widespread application of process analytical technology (PAT) have founded a robust foundation for neural network applications in crystallization research. This study investigated benzophenone antis...
Rare earth elements (REEs) are essential for permanent magnets that are vital for wind turbines and electric vehicles motors (EV), and are also used in a range of high-tech devices such as smartphones, digital cameras, and electronic displays. Nickel...
Scandium is a rare earth element that has been declared a critical raw material by the EU. Its availability is low but the demand for it is increasing. Bauxite residue presents a possible European source. A novel process to extract scandium from the...
In this work, the synthesis of zinc oxide (ZnO) photocatalyst from thermal decomposition of zinc acetate (ZnAc) nanoparticles obtained by supercritical antisolvent (SAS) precipitation was investigated. The optimization of calcination conditions of th...
Industrial process monitoring is an important field of research where different chemical processes are monitored and controlled. In this work, electrical impedance spectroscopy (EIS) was used to analyze antisolvent based crystallization of sucrose so...
Continuous crystallizations have promising potential for effectively controlling and modifying the crystal properties of active pharmaceutical ingredients (APIs). In this study, a continuous antisolvent sonocrystallization process was developed to re...
The crystal morphology of glucosamine hydrochloride (GAH) during antisolvent crystallization was investigated in this work. Particles of different shapes, such as plate-like crystals, leaflike clusters, fan-like dendrites, flower-like aggregates, and...
Antisolvent crystallization is a separation technology that separates the solute from the solvent by the addition of another solvent, in which the solute is sparingly soluble. High yields are achieved by using higher antisolvent-to-aqueous ratios, bu...
The crystallization quality of a perovskite active layer is highly sensitive to processing conditions and plays a decisive role in determining the performance of perovskite solar cells (PSCs). Herein, we systematically investigate the synergistic eff...
Paclitaxel (PTX) is a poor water-soluble antineoplastic drug with significant antitumor activity. However, its low bioavailability is a major obstacle for its biomedical applications. Thus, this experiment is designed to prepare PTX crystal powders t...
The viscosity values of CO2–dimethylphormamide, chloroform, methanol, isopropanol, ethyl acetate, acetone, and dimethyl sulfoxide mixtures were measured at a pressure of 150 bar and a temperature of 313 K. The correlation of the mean size of le...
Phosphogypsum is a solid waste with great environmental stockpile pressure produced by the wet production of phosphoric acid. Although there are various methods to purify and utilize phosphogypsum, the means for environmentally friendly, low energy c...
Solvent engineering is one of the most widely applied preparation methods for the high- quality perovskite films. In this method, the choice of anti-solvent plays a very important role to improve the perovskite crystal quality. Here, we report a faci...
All-inorganic CsPbX3 perovskites have significant potential for applications in the photovoltaic field. However, during their preparation, the slow evaporation rate of the precursor solution limits the extent of solution supersaturation, leading to p...
A bottom-up approach was investigated to produce long-acting injectable (LAI) suspension-based formulations to overcome specific limitations of top-down manufacturing methods by tailoring drug characteristics while making the methods more sustainable...
Perovskite Solar Cells are a promising solar energy harvesting technology due to their low cost and high-power conversion efficiency. A high-quality perovskite layer is fundamental for a highly efficient perovskite Solar Cell. Utilizing a gas quenchi...
In this contribution, crystallization was performed to assess the kinetics of nucleation and crystal growth of L-lactide. In most common solvents, this compound shows very high solubility even at low temperatures, which could be challenging for cryst...
The present work aims to investigate the applicability of ionic liquids (ILs) for natural ingredient crystallization. First, the medicinal plant, namely Angelica gigas Nakai, was extracted using methanol (MeOH) as a solvent. Afterwards, ILs 1-butyl-3...
In recent years, all-inorganic cesium lead bromide (CsPbBr3) perovskites have garnered considerable attention for their prospective applications in green photonics and optoelectronic devices. However, the development of efficient and economical metho...
Amorphous solids exhibit enhanced solubility and dissolution rates relative to their crystalline counterparts. However, attaining optimal bioavailability presents a challenge, primarily due to the need to maintain the physical stability of amorphous...
Bottom-up approaches to producing aqueous crystal suspensions of active pharmaceutical ingredients (APIs), such as anti-solvent crystallisation, are gaining interest as they offer better control over surface properties compared to top-down approaches...
High absorption ability and direct bandgap makes lead-based perovskite to acquire high photovoltaic performance. However, lead content in perovskite becomes a double-blade for counterbalancing photovoltaic performance and sustainability. Herein, we d...
The enhancement of the crystallization process through high pressures was studied by using ribavirin (RVB) as a model compound. The effects of high pressure on crystallization thermodynamics, nucleation kinetics, and process yield were evaluated and...
Crystallization-based separation of curcumin from ternary mixtures of curcuminoids having compositions comparable to commercial extracts was studied experimentally. Based on solubility and supersolubility data of both, pure curcumin and curcumin in p...
Solubility, bioavailability, permeation, polymorphism, and stability concerns associated to solid-state pharmaceuticals demand for effective solutions. To overcome some of these drawbacks, ionic liquids (ILs) have been investigated as solvents, reage...
Auricularia auricula-judae polysaccharide (AAP)-based nanoparticles (NPs) prepared via an anti-solvent precipitation approach were studied. Response surface methodology (RSM) design was carried out on the basis of single factor experiments, using ave...
Hierarchical organic structures have gained vast attention in the past decade owing to their great potential in chemical and medical applications in industries such as the food and pharmaceutical industries. In this paper, the crystallization of L-gl...
As a biopharmaceutics classification system (BCS) class IV drug, breviscapine (Bre) has low solubility in water, poor chemical stability, a short biological half-life and rapid removal from plasma. This paper prepared a Bre nanosuspension (Bre-NS) by...
The molecular structure of esomeprazole magnesium derivative in the solid-state is reported for the first time, along with a simplified crystallization pathway. The structure was determined using the single crystal X-ray diffraction technique to reve...
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