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6,071 Results Found

  • Article
  • Open Access
5 Citations
3,160 Views
13 Pages

The morphology of the brain undergoes changes throughout the aging process, and accurately predicting a person’s brain age and gender using brain morphology features can aid in detecting atypical brain patterns. Neuroimaging-based estimation of...

  • Article
  • Open Access
35 Citations
7,589 Views
14 Pages

Quantitative Variation of Flavonoids and Diterpenes in Leaves and Stems of Cistus ladanifer L. at Different Ages

  • Cristina Valares Masa,
  • Teresa Sosa Díaz,
  • Juan Carlos Alías Gallego and
  • Natividad Chaves Lobón

27 February 2016

The compounds derived from secondary metabolism in plants perform a variety of ecological functions, providing the plant with resistance to biotic and abiotic factors. The basal levels of these metabolites for each organ, tissue or cell type depend o...

  • Article
  • Open Access
1 Citations
1,175 Views
22 Pages

Age-Related Variations and Seasonal Influences: A Network Analysis of Comorbidities in Asthma Hospitalizations (2013–2023)

  • Ana Adriana Trusculescu,
  • Versavia Maria Ancusa,
  • Alexandra Burducescu,
  • Camelia Corina Pescaru,
  • Daniel Trăilă,
  • Norbert Wellmann,
  • Ovidiu Fira-Mladinescu and
  • Cristian Iulian Oancea

29 March 2025

Background: Asthma, a chronic respiratory disease characterized by airway inflammation and hyperresponsiveness, exhibits significant heterogeneity in its presentation. This study aimed to investigate age-related comorbidity patterns, seasonal variati...

  • Article
  • Open Access
5 Citations
2,684 Views
17 Pages

Age-Dependent Growth-Related QTL Variations in Pacific Abalone, Haliotis discus hannai

  • Kang Hee Kho,
  • Zahid Parvez Sukhan,
  • Shaharior Hossen,
  • Yusin Cho,
  • Won-Kyo Lee and
  • Ill-Sup Nou

29 August 2023

Pacific abalone is a high-value, commercially important marine invertebrate. It shows low growth as well as individual and yearly growth variation in aquaculture. Marker-assisted selection breeding could potentially resolve the problem of low and var...

  • Article
  • Open Access
8 Citations
4,109 Views
25 Pages

Intraday Variation Mapping of Population Age Structure via Urban-Functional-Region-Based Scaling

  • Yuncong Zhao,
  • Yuan Zhang,
  • Hongyan Wang,
  • Xin Du,
  • Qiangzi Li and
  • Jiong Zhu

22 February 2021

The spatial distribution of the population is uneven for various reasons, such as urban-rural differences and geographical conditions differences. As the basic element of the natural structure of the population, the age structure composition of popul...

  • Article
  • Open Access
3 Citations
3,840 Views
18 Pages

14 December 2022

South Korea’s successful reforestation efforts over the past 50 years have led to abundant forest resources. However, intensive reforestation during the 1970s and 1980s skewed the forests’ age distribution towards forest stands aged 30 ye...

  • Article
  • Open Access
1 Citations
2,949 Views
16 Pages

Background: Tongue anatomy plays a critical role in airway-related disorders such as obstructive sleep apnea (OSA). Understanding variations in tongue volume across age and gender is essential for refining diagnostic and therapeutic strategies. This...

  • Review
  • Open Access
15 Citations
4,278 Views
18 Pages

28 September 2021

The pericentric satellite III (SatIII or Sat3) and II tandem repeats recently appeared to be transcribed under stress conditions, and the transcripts were shown to play an essential role in the universal stress response. In this paper, we review the...

  • Article
  • Open Access
446 Views
25 Pages

CRHR1 Gene Copy Number Variations, Chronic Viral Infections, and Age as Correlates of Cognitive Impairment in Adults After SARS-CoV-2 Infection

  • Yekaterina Hovhannisyan,
  • Hermine Yeritsyan,
  • Hayk Harutyunyan,
  • Allen Azizian and
  • Konstantin Yenkoyan

Cognitive impairment is a frequent but heterogeneous consequence of SARS-CoV-2 infection, with objective cognitive deficits not always aligning with subjective cognitive complaints. Age, nutritional status, and stress-related biological pathways may...

  • Article
  • Open Access
8 Citations
3,343 Views
14 Pages

6 December 2022

Environmental variation likely modifies the life-history traits of vertebrates. As ectothermic vertebrates, it is possible that the body size of amphibians is impacted by environmental conditions. Here, we firstly quantified age and body size variati...

  • Article
  • Open Access
4 Citations
3,598 Views
9 Pages

24 August 2018

Aluminum profiles—for instance, profiles made of precipitation-hardenable alloys—are increasingly used for decorative details in the automotive industry. Typically, after hot extrusion and at least two to three days of natural aging (NA),...

  • Article
  • Open Access
14 Citations
4,697 Views
16 Pages

Effect of Barrel-to-Barrel Variation on Color and Phenolic Composition of a Red Wine

  • Leonard Pfahl,
  • Sofia Catarino,
  • Natacha Fontes,
  • António Graça and
  • Jorge Ricardo-da-Silva

20 July 2021

Tangible variation of sensory characteristics is often observed in wine aged in similar barrels. Barrel-to-barrel variation in barrel-aged wines was investigated in respect of the most important phenolic compounds of oenological interest. A red wine...

  • Article
  • Open Access
1 Citations
1,212 Views
19 Pages

Age-Related Variations in the Clinical Presentation and Treatment Outcomes of New-Onset GPA: A Longitudinal Study

  • Malgorzata Potentas-Policewicz,
  • Dariusz Gawryluk,
  • Elzbieta Wiatr and
  • Justyna Fijolek

25 February 2025

Background/Objectives: This study compares the clinical features and treatment outcomes of granulomatosis with polyangiitis (GPA) based on age at onset. Methods: A retrospective longitudinal cohort of patients with GPA diagnosed between January 1978...

  • Article
  • Open Access
24 Citations
3,393 Views
14 Pages

15 January 2021

At present, the filling mining method is widely used. To study strength evolution laws of cemented tailings backfill (CTB) under different curing ages, in the experiment, mine tailings were used as aggregates, ordinary Portland cement (PC32.5) was us...

  • Article
  • Open Access
1 Citations
2,797 Views
10 Pages

Geographical Variation in Body Size in the Asian Common Toad (Duttaphrynus melanostictus)

  • Kunhao Zhang,
  • Duojing Qiu,
  • Li Zhao,
  • Chengzhi Yan,
  • Long Jin and
  • Wenbo Liao

17 November 2023

The geographic variation in life-history traits of organisms and the mechanisms underlying adaptation are interesting ideas in evolutionary biology. This study investigated age and body size of the Asian common toad (Duttaphrynus melanostictus) among...

  • Review
  • Open Access
17 Citations
5,472 Views
14 Pages

Replicative Aging in Pathogenic Fungi

  • Somanon Bhattacharya,
  • Tejas Bouklas and
  • Bettina C. Fries

25 December 2020

Candida albicans, Candida auris, Candida glabrata, and Cryptococcus neoformans are pathogenic yeasts which can cause systemic infections in immune-compromised as well as immune-competent individuals. These yeasts undergo replicative aging analogous t...

  • Article
  • Open Access
1,028 Views
21 Pages

Comparison of Bacterial Community in the Jejunum, Ileum and Cecum of Suckling Lambs During Different Growth Stages

  • Mengrong Su,
  • Chunmei Du,
  • Wenjie Zhang,
  • Jie Liao,
  • Tao Li,
  • Shangquan Gan and
  • Jian Ma

Given that suckling lambs with immature rumen development rely on intestinal microbiota for nutrient utilization, investigating the composition and functional characteristics of their intestinal microbiota is therefore of paramount importance. In thi...

  • Article
  • Open Access
2 Citations
1,736 Views
17 Pages

11 July 2025

This study aims to analyse the effect of selected variation factors on the ejaculate characteristics of boars and to characterise changes in ejaculate characteristics in Landrace, Large White, Duroc, and Pietrain boars during their use for artificial...

  • Article
  • Open Access
1,569 Views
17 Pages

Immunophenotypic Profile of Normal Hematopoietic Populations in Human Bone Marrow: Influence of Gender and Aging as a Basis for Reference Value Establishment

  • Flavia Arandas de Sousa,
  • Rodolfo Patussi Correa,
  • Laiz Cameirão Bento,
  • Luiz Fabiano Presente Taniguchi,
  • Nydia Strachman Bacal and
  • Luciana Cavalheiro Marti

6 September 2025

The purpose of this study was to evaluate normal values of healthy human bone marrow (n = 56) and identify gender- and age-related variations using cell lineage markers and maturational curves. Using 10-color quantitative flow cytometry, various cell...

  • Article
  • Open Access
1 Citations
3,408 Views
12 Pages

Shifting Sands: Examining and Mapping the Population Structure of Greece Through the Last Three Censuses

  • Kleomenis Kalogeropoulos,
  • Dionysios Fragkopoulos,
  • Panagiotis Andreopoulos and
  • Alexandra Tragaki

29 October 2024

This paper aims to facilitate a more nuanced understanding of regional disparities in the population age structure at a local scale by applying a recent method for visualizing these disparities. Utilizing data from the three most recent population ce...

  • Article
  • Open Access
58 Citations
7,157 Views
15 Pages

17 January 2017

We currently have a poor understanding of how different soil sampling methods (pedogenetic horizon versus fixed-depth) influence the evaluation of soil properties. Here, 159 soil profiles were sampled from larch (Larix gmelinii) plantations in northe...

  • Article
  • Open Access
7 Citations
3,695 Views
16 Pages

Aging Determination of Series-Connected Lithium-Ion Cells Independent of Module Design

  • Thiemo Hein,
  • David Oeser,
  • Andreas Ziegler,
  • Daniel Montesinos-Miracle and
  • Ansgar Ackva

In this work, a battery consisting of eight commercial NMC/graphite cells connected in series was cycled to 60% of its initial capacity. During the test, special care was taken to ensure that the results were not influenced by either the module assem...

  • Article
  • Open Access
7 Citations
3,672 Views
18 Pages

Factors Affecting the Efficiency of In Vitro Embryo Production in Prepubertal Mediterranean Water Buffalo

  • Luke Currin,
  • Hernan Baldassarre,
  • Mariana Priotto de Macedo,
  • Werner Giehl Glanzner,
  • Karina Gutierrez,
  • Katerina Lazaris,
  • Vanessa Guay,
  • María Elena Carrillo Herrera,
  • Zigomar da Silva and
  • Vilceu Bordignon
  • + 3 authors

15 December 2022

Embryos from prepubertal water buffalo can be produced using laparoscopic ovum pickup (LOPU) and in vitro embryo production (IVEP). However, to date, it is unclear what factors and environmental conditions can affect LOPU-IVEP efficiency in prepubert...

  • Article
  • Open Access
1,371 Views
12 Pages

The Hainan gibbon (Nomascus hainanus) is one of the most endangered primates globally, threatened by habitat destruction, genetic diversity loss, and ecological competition. In this study, given the critical role of the gut microbiota in host immune...

  • Article
  • Open Access
12 Citations
4,248 Views
21 Pages

Neural Network Robustness Analysis Using Sensor Simulations for a Graphene-Based Semiconductor Gas Sensor

  • Sebastian A. Schober,
  • Yosra Bahri,
  • Cecilia Carbonelli and
  • Robert Wille

Despite their advantages regarding production costs and flexibility, chemiresistive gas sensors often show drawbacks in reproducibility, signal drift and ageing. As pattern recognition algorithms, such as neural networks, are operating on top of raw...

  • Article
  • Open Access
3 Citations
3,596 Views
19 Pages

18 December 2021

Due to its unique natural conditions and agricultural tradition, northeast China (NEC) has formed a distinctive open biomass burning habit with local-specific biomass burning aerosol features. In this research, with the help of a newly optimized biom...

  • Article
  • Open Access
1 Citations
1,082 Views
21 Pages

Genetic Variations in Bitter Taste Receptors and COVID-19 in the Canadian Longitudinal Study on Aging

  • Marziyeh Shafizadeh,
  • Mohd Wasif Khan,
  • Britt Drögemöller,
  • Chrysi Stavropoulou,
  • Philip St. John,
  • Rajinder P. Bhullar,
  • Prashen Chelikani and
  • Carol A. Hitchon

Background/Objectives: Bitter Taste Receptors (encoded by TAS2R genes) are expressed in mucosal and bronchial epithelia, as well as in immune cells, contributing to defense against airborne pathogens such as SARS-CoV-2. Data on single-nucleotide poly...

  • Article
  • Open Access
5 Citations
10,611 Views
22 Pages

Determinants of Spatial Heterogeneity of Functional Illiteracy among School-Aged Children in the Philippines: An Ecological Study

  • Kei Owada,
  • Mark Nielsen,
  • Colleen L. Lau,
  • Laith Yakob,
  • Archie C.A. Clements,
  • Lydia Leonardo and
  • Ricardo J. Soares Magalhães

Functional literacy is one of the targets of the Sustainable Development Goals (SDGs) of the United Nations. Functional literacy indicators are likely to vary between locations given the geographical variability of its major determinants. This proper...

  • Article
  • Open Access
1,312 Views
15 Pages

Introduction: The aim of this study was to investigate the spatial relationship between the incisive canal (IC) and apical region of the maxillary central incisors in the Korean population, using cone-beam computed tomography (CBCT) imaging. The find...

  • Article
  • Open Access
328 Views
15 Pages

12 January 2026

Background: Multimorbidity (the co-occurrence of two or more chronic conditions) is increasingly common among older adults and contributes to diminished well-being and greater healthcare use. While national data highlight regional variation, few stud...

  • Article
  • Open Access
1,376 Views
12 Pages

BPath-RO: A Performance- and Area-Efficient In Situ Delay Measurement Scheme for Digital IC

  • Danqing Li,
  • Huaguo Liang,
  • Hong Zhang,
  • Yue Wang,
  • Maoxiang Yi,
  • Yingchun Lu and
  • Zhengfeng Huang

30 November 2023

Circuit delays are increasingly sensitive to process, voltage, temperature, and aging (PVTA) variations, severely impacting circuit performance. Accurate measurement of circuit delay is essential. However, the additional hardware structures for measu...

  • Article
  • Open Access
27 Citations
6,001 Views
12 Pages

The purpose of the present study was to examine the effects of height-adjustable standing desks on time-series variation in sedentary behavior (SB) among primary school children. Thirty-eight children aged 11–12 years (22 boys and 16 girls) fro...

  • Article
  • Open Access
26 Citations
3,790 Views
13 Pages

The Cytogenomic “Theory of Everything”: Chromohelkosis May Underlie Chromosomal Instability and Mosaicism in Disease and Aging

  • Ivan Y. Iourov,
  • Svetlana G. Vorsanova,
  • Yuri B. Yurov,
  • Maria A. Zelenova,
  • Oxana S. Kurinnaia,
  • Kirill S. Vasin and
  • Sergei I. Kutsev

6 November 2020

Mechanisms for somatic chromosomal mosaicism (SCM) and chromosomal instability (CIN) are not completely understood. During molecular karyotyping and bioinformatic analyses of children with neurodevelopmental disorders and congenital malformations (n...

  • Article
  • Open Access
1 Citations
3,067 Views
23 Pages

Lifetime Variations of Prolactin Receptor Isoforms mRNA in the Hippocampus and Dentate Gyrus of the Rat—Effects of Aging

  • Marta Carretero-Hernández,
  • Elisa Herráez,
  • David Hernández-González,
  • David Díez-Castro,
  • Leonardo Catalano-Iniesta,
  • Josefa García-Barrado,
  • Enrique J. Blanco and
  • José Carretero

Prolactin is a hormone for which actions on the central nervous system such as neurogenesis and neuroprotection have been described by acting on specific receptors. The presence of prolactin receptors in the brain, including the hippocampus, is well...

  • Article
  • Open Access
192 Views
11 Pages

14 February 2026

Background: Acute tubulointerstitial nephritis (ATIN) is a significant yet under-monitored cause of U.S. mortality, particularly among the elderly. This study anrackalyzed national trends and demographic disparities in age-adjusted mortality rates (A...

  • Article
  • Open Access
20 Citations
4,665 Views
14 Pages

Understanding Variations in the Tracking and Erosion Performance of HTV-SR-Based Composites due to AC-Stressed Aging

  • Rahmat Ullah,
  • Muhammad Akbar,
  • Nasim Ullah,
  • Sattam Al Otaibi and
  • Ahmed Althobaiti

21 October 2021

Among the polymeric family, high-temperature-vulcanized silicone rubber (HTV-SR) is the most deployed material for high voltage insulation applications. However, in an outdoor environment, due to contamination and wetting-induced dry band arcing, con...

  • Hypothesis
  • Open Access
3 Citations
8,282 Views
14 Pages

Large Intra-Age Group Variation in Chromosome Abnormalities in Human Blastocysts

  • Sarthak Sawarkar,
  • Darren K. Griffin,
  • Lia Ribustello and
  • Santiago Munné

6 December 2021

Research Question: Is maternal age only a gross predictor of chromosome abnormalities in human embryos? Design: Here, we evaluated the less-studied variation in chromosome abnormality rates in embryos of patients within the same age group. Patients u...

  • Article
  • Open Access
1,132 Views
15 Pages

27 August 2025

Intra-specific variation in functional traits and their inter-relationships reflect how plants allocate resources, adapt, and evolve in response to environmental changes. This study investigated eight functional traits—leaf area (LA), specific...

  • Article
  • Open Access
1 Citations
1,908 Views
11 Pages

Urothelial Bladder Carcinoma in Young and Elderly Patients: Pathological Insights and Age-Related Variations

  • Andrada-Claudia Tătar,
  • Andrada Loghin,
  • Adela Nechifor-Boilă,
  • Andrada Raicea,
  • Maria-Cătălina Popelea,
  • Călin Chibelean,
  • Raul-Dumitru Gherasim and
  • Angela Borda

28 February 2025

Background/Objectives: UBC demonstrates a relatively low prevalence in patients under 50 years old. Our study aimed to compare the pathological characteristics of UBC in young and elderly patients and to assess the age-related variations in these cha...

  • Article
  • Open Access
15 Citations
5,060 Views
25 Pages

Multi-Dimensional Variation in Adult Speech as a Function of Age

  • Cécile Fougeron,
  • Fanny Guitard-Ivent and
  • Véronique Delvaux

25 October 2021

We present a multidimensional acoustic report describing variation in speech productions on data collected from 500 francophone adult speakers (20 to 93 y.o.a.) as a function of age. In this cross-sectional study, chronological age is considered as a...

  • Article
  • Open Access
20 Citations
3,784 Views
12 Pages

AGEs and sRAGE Variations at Different Timepoints in Patients with Chronic Kidney Disease

  • Paolo Molinari,
  • Lara Caldiroli,
  • Elena Dozio,
  • Roberta Rigolini,
  • Paola Giubbilini,
  • Massimiliano M. Corsi Romanelli,
  • Piergiorgio Messa and
  • Simone Vettoretti

15 December 2021

Patients with chronic kidney disease (CKD) are affected by enhanced oxidative stress and chronic inflammation, and these factors may contribute to increase advanced glycation end-products (AGEs). In this study we quantified AGEs and soluble receptors...

  • Article
  • Open Access
5 Citations
2,669 Views
12 Pages

Second derivative of photoplethysmogram (SDPTG) indices correlate with aging and vascular health. The trend of SDPTG indices with age has not yet been studied in the Korean population. Various SDPTG indices were measured in 300 healthy Koreans (150 m...

  • Article
  • Open Access
21 Citations
7,393 Views
12 Pages

Gender and Age Variations in Pharmacists’ Job Satisfaction in the United States

  • Manuel J. Carvajal,
  • Ioana Popovici and
  • Patrick C. Hardigan

While several studies have attested the presence of systematic gender and age variations in pharmacists’ satisfaction with their jobs, only a few of them have considered both classifications simultaneously. None have done so while systematicall...

  • Review
  • Open Access
23 Citations
8,581 Views
27 Pages

14 July 2021

Over the past 20 years, analyses of single brain cell genomes have revealed that the brain is composed of cells with myriad distinct genomes: the brain is a genomic mosaic, generated by a host of DNA sequence-altering processes that occur somatically...

  • Article
  • Open Access
3 Citations
3,207 Views
13 Pages

Age-Related Variation in the Provision of Primary Care Services and Medication Prescriptions for Patients with Cardiovascular Disease

  • Qiang Tu,
  • Karice Hyun,
  • Nashid Hafiz,
  • Andrew Knight,
  • Charlotte Hespe,
  • Clara K. Chow,
  • Tom Briffa,
  • Robyn Gallagher,
  • Christopher M. Reid and
  • Julie Redfern
  • + 9 authors

As population aging progresses, demands of patients with cardiovascular diseases (CVD) on the primary care services is inevitably increased. However, the utilisation of primary care services across varying age groups is unknown. The study aims to exp...

  • Article
  • Open Access
3 Citations
2,514 Views
14 Pages

Rectified Latent Variable Model-Based EMG Factorization of Inhibitory Muscle Synergy Components Related to Aging, Expertise and Force–Tempo Variations

  • Subing Huang,
  • Xiaoyu Guo,
  • Jodie J. Xie,
  • Kelvin Y. S. Lau,
  • Richard Liu,
  • Arthur D. P. Mak,
  • Vincent C. K. Cheung and
  • Rosa H. M. Chan

28 April 2024

Muscle synergy has been widely acknowledged as a possible strategy of neuromotor control, but current research has ignored the potential inhibitory components in muscle synergies. Our study aims to identify and characterize the inhibitory components...

  • Article
  • Open Access
7 Citations
5,187 Views
9 Pages

Sex and Age Effects on Monk Parakeet Home-Range Variation in the Urban Habitat

  • Juan Carlos Senar,
  • Aura Moyà,
  • Jorge Pujol,
  • Xavier Tomas and
  • Ben J. Hatchwell

6 December 2021

Home-range size is a key aspect of space-use, and variation in home-range size and structure may have profound consequences for the potential impact of damage and control strategies for invasive species. However, knowledge on home-range structure of...

  • Article
  • Open Access
629 Views
16 Pages

Age- and Sex-Dependent Variation in the Type I Interferon Signature of Healthy Individuals

  • Ilaria Galliano,
  • Matteo Volpe,
  • Cristina Calvi,
  • Marzia Pavan,
  • Anna Massobrio,
  • Stefano Gambarino,
  • Roberto Albiani,
  • Claudia Linari,
  • Anna Clemente and
  • Massimiliano Bergallo
  • + 2 authors

17 December 2025

Background and Objectives: Type I interferon (IFN-I) transcriptional signatures are widely utilised as readouts of innate immunity. We evaluated whether age and sex affect single interferon-stimulated genes (ISGs) and the composite IFN-I score, with...

  • Article
  • Open Access
2 Citations
1,834 Views
13 Pages

Age-Related Variations in Clinical Profiles for Children with Sports- and Recreation-Related Concussions

  • Sicong Ren,
  • Daniel J. Corwin,
  • Catherine C. McDonald,
  • Daniele Fedonni,
  • Christina L. Master and
  • Kristy B. Arbogast

14 September 2024

Objective: The purpose was to examine clinical profiles in concussed children aged 5–9 and 10–12 years and compare them with those of adolescents >12 years. Methods: This study included patients aged 5–18 years presenting to a sp...

  • Article
  • Open Access
12 Citations
3,232 Views
9 Pages

Interpopulation Similarity of Sex and Age-Related Body Composition Variations Among Older Adults

  • Elisabetta Marini,
  • Roberto Buffa,
  • Luis Alberto Gobbo,
  • Guillermo Salinas-Escudero,
  • Silvia Stagi,
  • Carmen García-Peña,
  • Sergio Sánchez-García and
  • María Fernanda Carrillo-Vega

The aim of the study was to analyze sex and age-related body composition variations among older adults from the Brazilian, Italian, and Mexican population. A cross-sectional analysis was conducted in 1103 community-dwelling older adults (634 women an...

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