333 Results Found

Background/Objectives: Host cell protein (HCP) content is a major attribute for biological and vaccine products that must be extensively characterized prior to product licensure. Enzyme Linked Immunosorbent Assay (ELISA) and Mass Spectrometry (MS) ar...

Background: Dystrophin Dp71 is one of the isoforms produced by the DMD gene which is mutated in patients with Duchenne muscular dystrophy (DMD). Although Dp71 is expressed ubiquitously, it has not been detected in normal skeletal muscle. This study w...

Traditional Western blotting is one of the most used analytical techniques in biological research. However, it can be time-consuming and suffer from a lack of reproducibility. Consequently, devices with different degrees of automation have been devel...

Due to the rapid developments in the aquaculture industry, Artemia franciscana, originally an American species, has been introduced to Eurasia, Africa and Australia. In the present study, we used a partial sequence of the mitochondrial DNA Cytochrome...

Background: The actin-binding protein Flightless-I (Flii) has not been quantified in the human serum yet. We aimed to determine serum Flii levels in healthy individuals and to investigate Flii as a potential marker in patients with sepsis focusing on...

Lipedema is a multifaceted chronic fat disorder characterized by the bilateral and disproportionate accumulation of fat predominantly in the lower body regions of females. Research strongly supports that estrogen factors likely contribute to the path...

Canine osteosarcoma (OSA) is an aggressive bone neoplasia with high metastatic potential. Metastasis is the main cause of death associated with OSA, and there is no current treatment available for metastatic disease. Proteomic analyses, including mat...

The Western lifestyle is a complex concept that includes the diet as the main axis of different factors which contribute to a detrimental effect on health, lower life expectancy and low quality-of-life. This type of diet is characterized by being hig...

Osteosarcoma (OSA) is the most common primary bone malignancy in dogs, characterized by aggressive growth and high metastatic potential. Despite advances in treatment, the prognosis for affected animals remains poor, mainly due to metastatic disease....

The Mediterranean coast is known for its great tourist attractions, concentration of population, and economic activities. Specifically, in the autonomous regions like Catalonia and Valencia, more than half of the population lives in coastal counties,...

This study aimed to accurately map burned forest areas and analyze the spatial distribution of forest fires under complex terrain conditions. This study integrates Landsat 8, Sentinel-2, and MODIS data to map burned forest areas in the complex terrai...

A warm ocean feature (WOF) is a blob of the ocean’s surface where the sea-surface temperature (SST) is anomalously warmer than its adjacent ambient SST. Examples are warm coastal seas in summer, western boundary currents, and warm eddies. Several stu...

We performed an animal study to identify the techniques associated with the best muscle healing outcomes in cleft lip/palate surgery. The right triceps of thirty adult male Sprague–Dawley rats were cut and repaired by three different suture technique...

Regional- and biome-scale paleoecological analyses and archaeological syntheses in the mountain landscapes of the western Pyrenees suggest that the Long Anthropocene began with agropastoral land use at the onset of the Neolithic. Historical and geogr...

Given the cost-effective nature of promoting desirable behaviors among individuals and societies, national and local governments have widely applied the nudge concept in various public policy fields. This viewpoint briefly explains the concept of nud...

We describe our approach to the Western Power Distribution (WPD) Presumed Open Data (POD) 6 MWh battery storage capacity forecasting competition, in which we finished second. The competition entails two distinct forecasting aims to maximise the daily...

Mesoscale eddy process with at least one splitting and/or merging event can be defined as either a complex process or a simple process. Investigation of the difference between these two categories could provide new insights into how different factors...

Oxygen deficiency and coldness are the main challenges for highway tunnel construction in high-altitude areas such as western Sichuan plateau. The artificial oxygen supply and anti-freezing structure in the tunnel construction process has a significa...

This study investigates the emotional tone in international news coverage of Saudi women’s empowerment, with a focus on their recruitment into the military as a milestone reform. The analysis is based on 22 news articles published between 2018...

A high consumption of fat and simple sugars, especially fructose, has been related to the development of insulin resistance, but the mechanisms involved in the effects of these nutrients are not fully understood. This study investigates the effects o...

Aircraft atmospheric profiling is a valuable technique for determining greenhouse gas fluxes at regional scales (10⁴–10⁶ km²). Here, we describe a new, simple method for estimating the surface influence of air samples that uses backward traject...

The increasing consumption of highly processed foods with high amounts of saturated fatty acids and simple carbohydrates is a major contributor to the burden of overweight and obesity. Additionally, an unhealthy diet in combination with chronic stres...

Non-alcoholic fatty liver disease (NAFLD) is one of the most frequent causes of chronic liver disease in the Western world, probably due to the growing prevalence of obesity, metabolic diseases, and exposure to some environmental agents. In certain p...

The present study focuses on finding potential sites for ecotourism development using GIS and remote-sensing-based weightage sum overlay techniques in Western Rajasthan, India. Ecotourism is one of the fastest growing and revenue-making sectors incor...

A convergent synthesis of four stereoisomers of the sex pheromone of the western corn rootworm (8-methyldecan-2-yl propionate, 1) from commercially available chiral starting materials is reported. The key step was Julia–Kocienski olefination between...

Allometric equations are useful tools for calculating tree and stand-level attributes, such as above-ground biomass or stem volume, using simple measurements that can be obtained from stand inventory data. These equations tend to be species-specific...

Detection of erythropoietin (Epo) was difficult until a method was developed by the World Anti-Doping Agency (WADA). WADA recommended the Western blot technique using isoelectric focusing (IEF)-PAGE to show that natural Epo and injected erythropoiesi...

To understand oxidative stress, antioxidant defense, and redox signaling in health and disease it is essential to assess protein thiol redox state. Protein thiol redox state is seldom assessed immunologically because of the inability to distinguish r...

Non-alcoholic fatty liver disease is one of the most common chronic liver diseases, ranging from simple steatosis to steatohepatitis, fibrosis, and cirrhosis. Its prevalence is rapidly increasing and presently affects around 25% of the general popula...

Gastrointestinal signals present a major challenge in magnetic particle imaging (MPI) because of their strong background interference. This study aimed to evaluate and compare the gut MPI signal in mice fed six commercially available diets in Austral...

Megacrystalline uraninite (up to one centimeter in size) represents one of the most important discoveries in uranium mineralogy in the western margin of the Yangtze Block and even in China in recent years. However, the genesis of megacrystalline uran...

G protein-coupled receptors (GPCRs) are regulated by GPCR kinases (GRKs) which phosphorylate intracellular domains of the active receptor. This results in the recruitment of arrestins, leading to desensitization and internalization of the GPCR. Aside...

(1) Background: Sub-Saharan Africa is experiencing the fastest urbanization worldwide. People in rural areas still have a traditional and rural lifestyle, whereas the Westernization of diet and lifestyle is already evident in urban areas. This study...

A fast and simple biotech method is presented for the simultaneous isolation and purification of transferrin (Tf) and immunoglobulin G (IgG) from the same pool-sample of human serum, yielding >98% pure proteins. Serum sample preparation was achiev...

Several parts of rose myrtle, Rhodomyrtus tomentosa, exhibited profound antibacterial and anti-inflammatory activities, suggesting its potential in healthcare and cosmetics applications. During the past few years, the demand for biologically active c...

We aimed to reveal the dispersal and gene flow of the local wild boar (Sus scrofa) population and find their genetic boundary in Fukushima Prefecture. After the nuclear incident in 2011, the land was considered a difficult-to-return zone, and the inc...

We investigated the spatial characteristics of heat extremes in South Korea from the climatological mean perspective. A heat extreme was defined as a day when the daily maximum temperature was higher than 33 °C. According to our analyses, the eas...

This article aims to offer Yi Kwangsu’s The Heartless (Mujŏng, 1917), the first modern Korean novel, as an emblem of hybrid religiosity in colonial modernity that sheds light on an ambivalent alterity in the problem of hell in non-Western...

A traditional Japanese diet (JD) has been widely regarded as healthy, contributing to longevity. The modern Japanese lifestyle has become markedly westernized, and it is speculated that the number of people who eat JD is decreasing. A simple evaluati...

This study investigates how listeners perceive consonance and dissonance in dyads composed of simple (sine) tones, focusing on the effects of frequency ratio (R) and mean frequency (F). Seventy adult participants—categorized by musical training...

The performance of empirical band ratio models were evaluated for the estimation of Coloured Dissolved Organic Matter (CDOM) using MODIS ocean colour sensor images and data collected on the North-Central Western Adriatic Sea (Mediterranean Sea). Rela...

Persimmon germplasm in the Western Caucasus represent one of the most northerly collections. In our study, 51 commercial cultivars of D. kaki, 3 accessions of D. virginiana and 57 D. lotus accessions from six geographically distant populations were i...

Projects to reduce emissions from deforestation and degradation (REDD) are designed to reduce carbon emissions through avoided deforestation and degradation, and in many cases, to produce additional community and biodiversity conservation co-benefits...

The objective of this study is to characterize and compare the relationships between dendrometric variables in Dipteryx spp. stands in the Western Amazon by fitting linear regression equations for total height (ht) and crown diameter (dc). Six forest...

Prolonged uninterrupted sitting and a typical Western meal, high in fat and refined sugar, can additively impair cognitive and cerebrovascular functions. However, it is unknown whether interrupting these behaviours, with a simple desk-based activity,...

Sea surface salinity (SSS) is a critical climate variable influencing ocean circulation, deep water formation, and the global hydrological cycle. This study evaluates a broad suite of satellite-derived SSS products against in situ measurements collec...

The apparel industry is changing dynamically and quickly to manufacturing sustainable fashion products and the development of sustainable design strategies that minimize material consumption at the source. This study addresses a critical research gap...

Non-alcoholic fatty liver disease (NAFLD) is considered the hepatic manifestation of metabolic syndrome and has become the major cause of chronic liver disease, especially in western countries. NAFLD encompasses a wide spectrum of hepatic histologica...

Goat may represent a valid large animal model for human pathogens and new vaccines testing. Appropriate vaccine administration is a critical component of a successful immunization program. The wrong route of administration may reduce the efficacy of...

Currently, several ocean data assimilation methods have been adopted to increase the performance of air–sea coupled models, but inconsistent adjustments between the sea temperature with other oceanic fields can be introduced. In the coupled model CAS...